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All Journal Pharmaciana: Jurnal Kefarmasian Pharmacon Jurnal Pemberdayaan Masyarakat Madani (JPMM) AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Community Empowerment Jurnal Abdi Masyarakat Indonesia Prosiding University Research Colloquium Nanggroe: Journal Of Scholarly Service Batik-Mu : Jurnal Pengabdian Masyarakat Jurnal Ilmiah Kesehatan Nanggroe: Journal of Scholarly Service Parapemikir Jurnal Ilmiah Farmasi CERATA Prosiding Seminar Kesehatan Masyarakat Jurnal Pengabdian Masyarakat Inovasi Indonesia
Ainun Muthoharoh, Ainun
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Penapisan Fitokimia, Penetapan Kadar Naftokuinon Total, Dan Aktivitas Antifungi Fraksi Tidak Larut Etil Asetat Ekstrak Etanol Daun Pacar Kuku (Lawsonia inermis L.) Terhadap Candida albicans ATCC 10231 zainab, zainab; Muthoharoh, Ainun
Pharmaciana Vol 5, No 2 (2015): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (372.048 KB) | DOI: 10.12928/pharmaciana.v5i2.2371

Abstract

Candidiasisis aninfection caused by Candida albicans. Synthetic treatment against Candida albicans have been developed, but reports of resistance to antifungal agents that there continue to emerge, and cause a lot of side effects. Pacar kuku (Lawsonia inermis L.) is one of the plants that have antifungal activity. Chemical contentof polyphenols inhibit candidiasis is a form of naphthoquinone. This study aimed to test the antifungal activity of insoluble ethyl acetate fraction of ethanolic extract of pacar kuku leaves against Candida albicans. Insoluble fraction obtained from the ethyl acetate extraction of previously fractionated with ethyl acetate. Identification of chemical compounds made with phytochemical screening. Test antifungal activity against Candida albicans using microdilution method. Drugs used for comparison is amphoterisin B infusion in doses 250 µg/ml with the concentration of 1,5 µg/ml, 0,75 µg/ml, 0,375 µg/ml, 0,187 µg/ml, 0,0937 µg/ml, dan 0,0469 µg/ml,. The parameters in this study are the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC). The concentration of the fraction used in the MIC and MFC test is the concentration of 80%, 40%, 20%, 10%, 5%, 2,5% w/v. Identification of chemical compounds made with test tubes and assay on anthraquinone compounds. The results showed that the MFC of ethyl acetate insoluble fraction of ethanol extract of leaves pacar kuku is 40% w/v. MIC and MFC amphoterisin B respectively 0,0937 µg/ml and 0,187 µg/ml. Test tubes showed that the ethyl acetate insoluble fraction of ethanol extract of leaves pacar kuku containing polyphenols, saponins, and quinone. The naphtoquinone total content in insoluble ethyl acetate fraction of ethanolic extract of pacar kuku leaves consecutively 7,97±0,14%. The conclusion showed that insoluble ethyl acetate fraction of ethanolic extract of pacar kuku leaves have antifungal activity. Keywords: Lawsonia inermis L., Candida albicans, microdilution, MIC, MFC, naphtoquinone content
Pola Pengobatan Antidiabetik Oral pada Pasien Diabetes Mellitus Tipe 2 Rawat Jalan di RSUD Kajen Pekalongan Muthoharoh, Ainun; Safitri, Wiga Arum; Pambudi, Dwi Bagus; Rahman, Fadila
Pharmacon: Jurnal Farmasi Indonesia Edisi Khusus: RAKERDA, SEMINAR, PID IAI
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v0i0.10841

Abstract

Diabetes mellitus is a chronic disease with long-term and routine treatment therapy. Combined or single oral antidiabetic therapy is given to be able to get normal and controlled blood sugar levels every month. The purpose of this study was to determine the treatment patterns in patients with type 2 diabetes mellitus outpatient at Kajen Regional Hospital in Pekalongan Regency. This study used an observational cross sectional approach which was conducted retrospectively. A total of 97 samples were taken from the medical records of type 2 diabetes mellitus patients who received oral antidiabetic drug therapy, who had routine medical treatment for 3 consecutive months in the Outpatient Installation of Kajen Regional Hospital in Pekalongan Regency for the period January-December 2017. Data analysis was conducted descriptively. The results of this study that patients with uncomplicated diabetes mellitus receive the most oral antidiabetic drugs with metformin, patients with diabetes mellitus with the most complications receive oral antidiabetic drugs pioglitazone and acarbose, and the type of drugs other than oral antidiabetics is aspilet. The need for special assessment of individual doses in patients with diabetes mellitus without or with pharmacokinetic and pharmacogenomic perspective complications
Communication, information, and education (CIE) on food safety issues in Kalimojosari Village, Pekalongan Muthoharoh, Ainun; Waznah, Urmatul; Slamet, Slamet; Rahmasari, Khusna Santika; Nur, Achmad Vandian
Community Empowerment Vol 6 No 7 (2021)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.769 KB) | DOI: 10.31603/ce.4933

Abstract

Food safety issues in Indonesia are still a common concern. Lack of knowledge causes the number of food safety cases is increasing, such as snack poisoning and diarrhea. This community service was carried out to form the PKK Food Safety Cadre in Kalimojosari Village which is expected to provide information and education to local residents regarding food safety. The implementation method applied was communication, information, and education counseling through the lecture method. The result of this community service activity is an increase in knowledge about food safety issues by 6.08%.
Pemanfatan Tanaman Obat Herbal Untuk Penyakit Degeneratif Pada Kelompok Ibu-Ibu Pca Kabupaten Pekalongan Slamet, Slamet; Muthoharoh, Ainun; Pambudi, Dwi Bagus; Fuad, Asfal; Setianto, Gigih
Nanggroe: Jurnal Pengabdian Cendikia Vol 2, No 10 (2024): Januari
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.10562528

Abstract

Degenerative disease is a disease that usually occurs in old people. This disease accompanies the age of a person who has decreased organ function due to old age. Sick humans will try to treat minimal illnesses by utilizing plants that grow around them. The aim of this PkM is to introduce plants that are around us for the treatment of these degenerative diseases. The method used is lecture accompanied by questions and answers. The results obtained from this PkM are additional knowledge and understanding about herbal plants that can be used for the treatment of degenerative diseases such as hypertension, cholesterol, arthritis, gout and diabetes and how to make medicinal preparations. The results of understanding the material presented are measured by the results of the pre-test and post-test.
Food Safety Education for Pregnant and Breastfeeding Mothers, Toddlers, Adolescents, and the Elderly Muthoharoh, Ainun; Rejeki, Herni; Pambudi, Dwi Bagus; Khuzaiyah, Siti; B., Mahdanya Puteri A.
Jurnal Pemberdayaan Masyarakat Madani (JPMM) Vol. 7 No. 1 (2023): Jurnal Pemberdayaan Masyarakat Madani (JPMM) (DOAJ & SINTA 3 Indexed)
Publisher : Fakultas Ekonomi dan Bisnis Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JPMM.007.1.02

Abstract

Quality food products, halal, free from microbial and chemical contamination, and containing harmless ingredients are the criteria for food products that are suitable for consumption. Especially the use of food products for pregnant and lactating mothers, toddlers, and the elderly must be products that should not be careless. This food safety information can be obtained through education provided in community service activities. Community service activities are carried out by religious leaders and influential community leaders, namely PKK cadres in Ketitang Lor Village, Bojong District, PKK cadres in Sabarwangi Village, Kajen District, Aisyiyah Regional Leaders (PDA) Pekalongan Regency, Nasyiatul Aisyiyah Regional Leaders (PDNA) Pekalongan Regency. This activity is expected to provide an overview and knowledge about the safety of food products for pregnant and lactating mothers, toddlers, children, adolescents and the elderly. The implementation method used is to conduct Communication, Information, and Education (KIE) counseling with the lecture method and discussion. Assessment of knowledge improvement by giving pretest and posttest questionnaires. This activity provides an overview for participants to be able to inform pregnant, lactating mothers, foster parents of infants and adolescents, and the elderly to consume safe and healthy food. Participants are interested and cooperative in participating in the activities. The results of the activity showed an increase in knowledge of 3.21%.
Peningkatan Pengetahuan Masyarakat Terhadap Aromaterapi Sebagai Alternatif Pengobatan TBC Paru-Paru Rahmatullah, St.; Irnawati, Irnawati; Wahyu Permadi, Yulian; Muthoharoh, Ainun; Rahmadhani, Aulia; Saadatina, Nilna
Jurnal Pengabdian Masyarakat Sains Indonesia Vol. 6 No. 1 (2024): Juni
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmsi.v6i1.282

Abstract

Indonesia merupakan salah satu diantara beberapa negara dengan kasus penyakit Tuberkolosis tertinggi untuk saat ini. Tuberkolosis merupakan suatu penyakit yang disebabkan oleh Mycobacterium tuberculosis yang ditularkan melalaui droplet (cairan yang keluar dari hidung ataupun mulut) seseorang yang menderita penyakit ini, baik pada saat batuk, bersin, bahkan berbicara. Salah satu terapi alami untuk dapat mengurangi gejala respiratorik pada pasien TBC PARU yaitu dengan menggunakan aromaterapi. Intervensi aromaterapi yang menggunakan bahan-bahan alam ini, dapat dijadikan terapi pendamping pengobatan farmakologis pada pasien TBC PARU Paru dengan gejala utama sesak napas. Pelaksanaan kegiatan dilakukan dengan cara pemberian edukasi menggunakan metode talkshow. Pemberian pretest dan postest dilakukan kemudian uji statistik menggunakan paired t-test. Hasil kegiatan pengabdian menunjukkan bahwa ada peningkatan pengetahuan tentang TBC PARU serta signifikan secara statistic terdapat pengaruh edukasi terhadap peningkatan pengetahuan.
Identifikasi DRPs Penggunaan Insulin Pada Pasien DM Tipe 2 Komplikasi Gagal Ginjal kronis Wijayanti, Tika Yusnia; Muthoharoh, Ainun; Permadi, Yulian Wahyu; Ningrum, Wulan Agustin
CERATA Jurnal Ilmu Farmasi Vol 14 No 2 (2023): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v14i2.874

Abstract

DM tipe 2 adalah penyakit yang ditandai dengan hiperglikemia karena mengalami penurunan sekresi insulin dan gaya hidup yang tidak teratur yang merupakan penyebab utama komplikasi gagal ginjal kronis. Penyakit berkomplikasi dapat mengakibatkan timbulnya terjadinya masalah yang berkaitan dengan obat. Penelitian ini bertujuan untuk mengetahui adanya DRPs penggunaan insulin pada pasien DM tipe 2 komplikasi gagal ginjal kronis di instalasi rawat inap RSUD Kajen Kabupaten Pekalongan periode 6 Mei-6 Juni 2023. Penelitian ini merupakan jenis penelitian dengan rancangan metode deskriptif dengan menggunakan implementasi prospektif. Data didapatkan dengan mengidentifikasi rekam medis dan melakukan wawancara selama rawat inap pada pasien DM tipe 2 komplikasi gagal ginjal kronis. Terdapat 2 pasien yang memenuhi kriteria inklusi dalam penelitian ini. Hasil penelitian DRPs menurut PCNE V9.01 yang terdiri dari efektivitas pengobatan, keamanan terapi, pemilihan obat dan pemilihan dosis, yaitu terdapat 2 kejadian DRPs penggunaan insulin pada pasien DM tipe 2 komplikasi gagal ginjal kronis yaitu pemilihan obat dengan kategori obat tidak tepat menurut pedoman dan DRPs pemilihan dosis dengan kategori dosis obat terlalu tinggi.
SURVEY GEJALA dan PENGOBATAN yang DILAKUKAN MASYARAKAT JAWA TENGAH PASCA VAKSIN COVID-19 Muthoharoh, Ainun; Waznah, Urmatul
Parapemikir : Jurnal Ilmiah Farmasi Vol 13, No 3 (2024): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v13i3.5224

Abstract

Vaksin covid-19 dapat menyebabkan gejala efek samping. Gejala efek samping akibat vaksin covid-19 yang ringan dikenal dengan istilah Kejadian Ikutan Pasca Imunisasi (KIPI) atau Adverse Events Following Immunization (AEFI). yang dirasakan dapat ditangani oleh masyarakat sendiri melalui pengobatan mandiri obat kimia maupun herbal. Penelitian ini bertujuan untuk mengetahui gejala dan menganalisis pengobatan mandiri yang dilakukan oleh masyarakat Jawa Tengah pasca vaksin covid-19. Metode penelitian yang digunakan adalah survey. Data penelitian diambil dengan teknik random sampling pada tahun 2021. Sampel diperoleh sebanyak 56 responden yang memenuhi kriteria inklusi. Analisis data yang digunakan adalah analisis dekriptif. Hasil penelitian menunjukkan gejala yang dialami masyarakat adalah nyeri/pegal, demam, mual, muntah, dan mengantuk. Obat yang dikonsumsi meliputi Parasetamol, Demacoline®, Pamol®, Panadol®, Sanmol®, dan Imboost®, sedangkan herbal yang dikonsumsi yaitu air kelapa, jahe, madu, dan spirulina. Berdasarkan gejala KIPI pasca vaksin covid-19, dapat disimpulkan bahwa Demacoline® bukanlah obat yang tepat yang dikonsumsi oleh masyarakat karena tidak menunjukkan gejala seperti pilek
Edukasi Swamedikasi kepada Masyarakat tentang Gejala Penyakit Degeneratif di Klinik PKU Muhammadiyah Comal, Pemalang Handayani, Widyastuti; Muthoharoh, Ainun; Kusuma, Nur Intan; Tina, Nilna Saada; Nabiilah, Alya
Jurnal Abdi Masyarakat Indonesia Vol 5 No 1 (2025): JAMSI - Januari 2025
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jamsi.1418

Abstract

Dalam Kehidupan ini yang dialami semua orang adalah penuaan, Pada tingkat usia tertentu terjadi perubahan tubuh yang biasanya bersifat degeneratif cenderung mengakumulasi perubahan. Pengabdian Masyarakat ini bertujuan untuk Melakukan edukasi swamediakasi sesuai dengan gejala penyakitnya. Populasi yang digunakan adalah Pasien Prolanis di Klinik Pratama Rawat Inap PKU Muhammadiyah Comal Pemalang dan sekitarnya. Permasalahan yang dihadapi Pasien Prolanis di Klinik PKU adalah kurangnya pemantauan dari keluarga sehingga terapi tidak tercapai. Sehingga perlu dilakukan edukasi ini untuk meningkatkan pengetahuan Pasien prolanis tentang swamedikasi ini. Metode yang digunakan adalah studi prospektif yang melibatkan analisis data hasil prosentase pretest dan post test peserta yang mengikuti edukasi. Metode ini dapat dilakukan dalam praktek klinis untuk memberikan edukasi untuk meningkatkan pengetahuan dari peserta Pasien prolanis. Data yang dikumpulkan meliputi hasil pre test dan hasil post test dan prosentase peningkatan pengetahuan dari peserta. Hasil edukasi swamedikasi diharapkan dapat menunjukkan gambaran tingkat pengetahuan peserta dan dapat membantu mitra dalam mengurangi swamedikasi yang tidak rasional. Hasil dari pengambilan sampel sejumlah 14 orang, prosentase rata pretest sebesar 95,71 % dan post test sebesar 99,29%. Setelah dilakukan Edukasi peningkatan pengetahuan sampel sebesar 3,57%. Kesimpulan dari Edukasi ini adalah meningkatnya pengetahuan masyarakat setelah mendapatkan Edukasi swamedikasi kepada masyarakat tentang gejala penyakit degenerative.
Efektivitas Penggunaan Antibiotik Golongan Sefalosporin Pada Terapi Demam Tifoid Pediatri Rawat Inap Zalfa, Saniyyah; Muthoharoh, Ainun; Rahmatullah, St.; Ningrum, Wulan Agustin
Jurnal Ilmiah Kesehatan Vol. 17 No. 2 (2024): Jurnal Ilmiah Kesehatan
Publisher : Universitas Muhammadiyah Pekajangan Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48144/jiks.v17i2.1944

Abstract

Typhoid fever is caused by an infection with the bacterium Salmonella typhi. Typhoid fever remains a public health issue around the world, particularly in developing countries with inadequate sanitation and high population density. The achievement of the desired treatment regimen is indicated by treatment efficacy. Irrational drug use can make treatment ineffective. The antibiotics used are third generation cephalosporins. The purpose of this study was to determine the risk factors and effectiveness of thirdgeneration cephalosporin antibiotics in pediatric typhoid fever patients based on the type of antibiotic used, length of treatment, and fever-free time. This study is designed as prospective cross-sectional research with total sampling, where interviews are conducted with patients and medical record data is reviewed. Data analysis was conducted using both univariate and bivariate methods, employing the Independent T-test and MannWhitney statistical tests with SPSS version 16. Typhoid fever patients were male (67.6%) and female (32.4%). The majority of patients (67.6%) were aged 5 to 13 years. A habit of random snacking poses the highest risk, accounting for 91.1%. Mann-Whitney test showed a significant result for length of treatment days (p-value < 0.001). Similarly, independent t-test for Fever-free time showed p-value = 0.01 (< 0.05). In conclusion, ceftriaxon antibiotics are more effective than cefixime with a significant difference
Co-Authors Abdullah, Dede Agung Achmad Vandian Nur, Achmad Vandian Asqiya, Aurisna Isma B., Mahdanya Puteri A. Bahrie, M Syaeful Eka Budiarto, Eka Fachry Abda El Rahman Febriyani, Widya Fuad, Asfal Handayani, Widyastuti Herni Rejeki iana, Nur D Irnawati Irnawati Isfaki, Baiti Islamy, Shavira Novita Jaka Panuntun, Eko Kholifatu Balqis, Nurmalia Khusna Santika Rahmasari Khusna, Nabilatul Kusuma, Nur Intan LIA AMALIA Listiana, Tia Melinia, Devi Nabiilah, Alya Nabila, Yustiana Nina Zuhana Ningrum, Wulan Agustin Nisa, Rahma Dian Nizmah Fajriyah, Nuniek Noviawati, Sabila Nuniek Nizmah Fajriyah Nur Diana Pambudi, Dwi Bagus Rahayuningtyas, Wanda Rahman, Fadila Rahmatullah, St Rahmatullah, ST. Rosmalinda, Diana S Slamet, S Saadatina, Nilna Safabela, Vania Safitri, Wiga Arum Sandi Ari Susiatmi, Sandi Ari Sari, Vera Kartika Sa’diyah, Aminatus Septyarini, Diyas Setianto, Gigih Siti Helmyati Siti Khuzaiyah, Siti Slamet . Slamet Riyadi Syarifah, Nailati Tina, Nilna Saada Urmatul Waznah Wahyu Permadi, Yulian Widiyastuti, Windha Wijayanti, Tika Yusnia Wirasti, W Yulian Wahyu Permadi Zainab Zainab Zalfa, Saniyyah Zulvania, Alda