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All Journal LINK Pharmacon Jurnal Pemberdayaan Masyarakat Madani (JPMM) Prosiding University Research Colloquium Nanggroe: Journal Of Scholarly Service Journal of Pharmacy Science and Technology Nanggroe: Journal of Scholarly Service Benzena Pharmaceutical Scientific Journal Kartika : Jurnal Ilmiah Farmasi Baktimu : Jurnal Pengabdian Kepada Masyarakat Journal of Nutraceuticals and Herbal Medicine
Pambudi, Dwi Bagus
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Pola Pengobatan Antidiabetik Oral pada Pasien Diabetes Mellitus Tipe 2 Rawat Jalan di RSUD Kajen Pekalongan Muthoharoh, Ainun; Safitri, Wiga Arum; Pambudi, Dwi Bagus; Rahman, Fadila
Pharmacon: Jurnal Farmasi Indonesia Edisi Khusus: RAKERDA, SEMINAR, PID IAI
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v0i0.10841

Abstract

Diabetes mellitus is a chronic disease with long-term and routine treatment therapy. Combined or single oral antidiabetic therapy is given to be able to get normal and controlled blood sugar levels every month. The purpose of this study was to determine the treatment patterns in patients with type 2 diabetes mellitus outpatient at Kajen Regional Hospital in Pekalongan Regency. This study used an observational cross sectional approach which was conducted retrospectively. A total of 97 samples were taken from the medical records of type 2 diabetes mellitus patients who received oral antidiabetic drug therapy, who had routine medical treatment for 3 consecutive months in the Outpatient Installation of Kajen Regional Hospital in Pekalongan Regency for the period January-December 2017. Data analysis was conducted descriptively. The results of this study that patients with uncomplicated diabetes mellitus receive the most oral antidiabetic drugs with metformin, patients with diabetes mellitus with the most complications receive oral antidiabetic drugs pioglitazone and acarbose, and the type of drugs other than oral antidiabetics is aspilet. The need for special assessment of individual doses in patients with diabetes mellitus without or with pharmacokinetic and pharmacogenomic perspective complications
Pemanfatan Tanaman Obat Herbal Untuk Penyakit Degeneratif Pada Kelompok Ibu-Ibu Pca Kabupaten Pekalongan Slamet, Slamet; Muthoharoh, Ainun; Pambudi, Dwi Bagus; Fuad, Asfal; Setianto, Gigih
Nanggroe: Jurnal Pengabdian Cendikia Vol 2, No 10 (2024): Januari
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.10562528

Abstract

Degenerative disease is a disease that usually occurs in old people. This disease accompanies the age of a person who has decreased organ function due to old age. Sick humans will try to treat minimal illnesses by utilizing plants that grow around them. The aim of this PkM is to introduce plants that are around us for the treatment of these degenerative diseases. The method used is lecture accompanied by questions and answers. The results obtained from this PkM are additional knowledge and understanding about herbal plants that can be used for the treatment of degenerative diseases such as hypertension, cholesterol, arthritis, gout and diabetes and how to make medicinal preparations. The results of understanding the material presented are measured by the results of the pre-test and post-test.
Food Safety Education for Pregnant and Breastfeeding Mothers, Toddlers, Adolescents, and the Elderly Muthoharoh, Ainun; Rejeki, Herni; Pambudi, Dwi Bagus; Khuzaiyah, Siti; B., Mahdanya Puteri A.
Jurnal Pemberdayaan Masyarakat Madani (JPMM) Vol. 7 No. 1 (2023): Jurnal Pemberdayaan Masyarakat Madani (JPMM) (DOAJ & SINTA 3 Indexed)
Publisher : Fakultas Ekonomi dan Bisnis Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JPMM.007.1.02

Abstract

Quality food products, halal, free from microbial and chemical contamination, and containing harmless ingredients are the criteria for food products that are suitable for consumption. Especially the use of food products for pregnant and lactating mothers, toddlers, and the elderly must be products that should not be careless. This food safety information can be obtained through education provided in community service activities. Community service activities are carried out by religious leaders and influential community leaders, namely PKK cadres in Ketitang Lor Village, Bojong District, PKK cadres in Sabarwangi Village, Kajen District, Aisyiyah Regional Leaders (PDA) Pekalongan Regency, Nasyiatul Aisyiyah Regional Leaders (PDNA) Pekalongan Regency. This activity is expected to provide an overview and knowledge about the safety of food products for pregnant and lactating mothers, toddlers, children, adolescents and the elderly. The implementation method used is to conduct Communication, Information, and Education (KIE) counseling with the lecture method and discussion. Assessment of knowledge improvement by giving pretest and posttest questionnaires. This activity provides an overview for participants to be able to inform pregnant, lactating mothers, foster parents of infants and adolescents, and the elderly to consume safe and healthy food. Participants are interested and cooperative in participating in the activities. The results of the activity showed an increase in knowledge of 3.21%.
PEMBERDAYAAN IBU-IBU AISYIAH DALAM PEMBUATAN SEDIAAN OBAT TRADISIONAL DARI TANAMAN HERBAL DI RUMAH LANSIA KABUPATEN PEKALONGAN Obat Tradisional dari Tanaman Herbal di Rumah Lansia Kabupaten Pekalongan Pambudi, Dwi Bagus; Ainun Muthoharoh; Slamet , Slamet
BAKTIMU : Jurnal Pengabdian Kepada Masyarakat Vol 4 No 3 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/bm.v4i3.1308

Abstract

Obat tradisional merupakan obat-obatan yang diolah secara tradisional, turun temurun, berdasarkan resep nenek moyang, adat-istiadat, kepercayaan, atau kebiasaan setempat, baik bersifat magic maupun pengetahuan tradisional. Menurut penelitian masa kini, obat-obatan tradisional memang bermanfaat bagi kesehatan dan saat ini penggunaannya cukup gencar dilakukan karena lebih mudah dijangkau masyarakat, baik harga maupun ketersediaannya. Obat tradisional pada saat ini banyak digunakan karena menurut beberapa penelitian tidak terlalu menyebabkan efek samping, karena masih bisa dicerna oleh tubuh. Bagian dari obat tradisional yang banyak digunakan atau dimanfaatkan masyarakat diantaranya akar, rimpang, batang, buah, daun dan bunga. Pada hakikatnya, masyarakat dalam kehidupannya menempatkan tanaman sebagai salah satu komponen penting dalam pemenuhan kebutuhan hidupnya sehari-hari. Kebutuhan tersebut meliputi peran tanaman sebagai tanaman obat. Sehingga pemanfaatan tanaman sebagai obat masih dipertahankan oleh masyarakat. Prodi Sarjana Farmasi Fakultas Ilmu Kesehatan Universitas Muhammadiyah Pekajangan Pekalongan bersama mitra pengabdian masyarakat yakni Pimpinan Daerah Aisyiyah Kab. Pekalongan bekerja sama untuk meningkatkan kesehatan para anggota Aisyiyah untuk beberapa keluhan kesehatan yang timbul di masyarakat. Upaya dalam peningkatkan kesehatan tersebut dilakukan dengan pemberian obat herbal yang tumbuh di daerah sekitar. Kata kunci: Pemberdayaan, sediaan obat tradisional, tanaman herbal
Determination Of Total Phenolic, Flavonoid Contents, And Antioxidant Activity Evaluation of Ethanolic Extract From Plumeria Alba Attasih, Monicia; Muhtadi; Pambudi, Dwi Bagus; Saad, Muhammad
Journal of Nutraceuticals and Herbal Medicine Vol 5, No 1 (2024): JNHM 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v5i1.3700

Abstract

A polluted environment and an unhealthy lifestyle can result in an increase in the number of free radicals in the body. This condition can be reduced by consuming antioxidant-rich plants. This study aims to determine the antioxidant activity of the ethanol extract of the Cambodian plant (Plumeria alba L.) and its correlation with phenolic and flavonoid levels. Sample extraction was carried out using the maceration method, antioxidant activity was measured using the DPPH and CUPRAC methods, and total flavonoid and phenolic levels were measured using the spectrophotometer method. The results showed that the ethanol extract of P. alba L stems had inactive antioxidant activity, while the ethanol extract of P. alba L flowers and leaves had weak antioxidant activity with IC50 values of 266.72 ppm and 312.96 ppm. The ethanol extract of P. alba L flowers and leaves has an antioxidant capacity of 208.82 and 207.81 mg trolox equivalent/g extract. The total phenolic content measured from the ethanol extract of P alba L flowers and leaves was 2.28 and 48.43 mg gallic acid equivalent/g extract, while the flavonoid content was 29.73 and 31.26 mg quercetin equivalent/g extract. The antioxidant activity of the extract was positively correlated with phenolic and flavonoid levels.
White Mangrove Pidada (Sonneratia Alba) Leaves Extract in Handbody Lotions: A Qualitative Evaluation and Alignment With Indonesian National Standards Nisa, Husna Idza Auziadzatun; Pambudi, Dwi Bagus; Mugiyanto, Eko
Journal of Nutraceuticals and Herbal Medicine Vol 5, No 1 (2024): JNHM 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v5i1.4409

Abstract

The White Mangrove Pidada Leaves (Sonneratia alba) serve as a source of secondary metabolites, including phenols, tannins, steroids, and flavonoids, known for their high antioxidant content, making them effective in countering free radicals. The choice of a handbody lotion formulation is based on its easy skin absorption, non-sticky nature, and absence of residue upon application. The focus of this study is to evaluate the handbody lotion formulation enriched with White Mangrove Pidada Leaves extract. Utilizing a qualitative approach, this study employed a cycling test conducted over three cycles for the evaluation of handbody lotion formulations. After three cycles, Formula A demonstrated a semi-solid consistency, light green color with a grape scent, pH 6, and homogeneity. Notably, it showcased a spreadability of 4.925 cm, adhesiveness of 1.76 seconds, and viscosity of 6.791 mPa.S. In the case of Formula B, a semi-solid with a light green color and grape scent, despite having pH 6, exhibited a lack of homogeneity, with a spreadability of 5.175 cm, adhesiveness of 1.37 seconds, and viscosity of 6.592 mPa.S. Formula C, characterized as a semi-solid with a dark green color and grape scent, displayed homogeneity, pH 6, a spreadability of 5.25 cm, adhesiveness of 2 seconds, and viscosity of 7.568 mPa.S. The findings lead to the conclusion that, following three cycles, the handbody lotion formulations align with the criteria established by the Indonesian National Standard (SNI).
AKTIVITAS PENGHAMBATAN α-AMILASE OLEH EKSTRAK DAUN BAKAU MERAH (Rhizophora stylosa) Ayu Dyah Purwati; Pambudi, Dwi Bagus; Wirasti; Khusna Santika Rahmasari
BENZENA Pharmaceutical Scientific Journal Vol 3 No 02 (2024): BENZENA PHARMACEUTICAL SCIENTIFIC JOURNAL
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/benzena.v3i02.5101

Abstract

Diabetes melitus merupakan salah satu penyakit degeneratif yang prevalensinya terus meningkat di Indonesia. Penelitian ini bertujuan untuk mengevaluasi potensi daun bakau merah (Rhizophora stylosa) sebagai agen antidiabetes alami melalui penghambatan enzim α-amilase. Ekstrak etanol daun bakau merah diperoleh melalui metode maserasi. Skrining fitokimia dilakukan untuk mengidentifikasi senyawa bioaktif. Aktivitas penghambatan α-amilase diuji menggunakan metode spektrofotometri dengan acarbose sebagai kontrol positif. Hasil penelitian menunjukkan bahwa ekstrak etanol memiliki aktivitas penghambatan α-amilase yang sangat aktif dengan nilai IC50 16,074 μg/mL lebih rendah dibandingkan acarbose (20,607 μg/mL). Skrining fitokimia mengungkapkan keberadaan alkaloid, flavonoid, fenol, saponin, steroid, dan tanin yang berpotensi berkontribusi terhadap aktivitas penghambatan α-amilase.Kata kunci: Rhizophora stylosa, penghambatan α-amilase, antidiabetes. 
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BUAH BAKAU MINYAK (Rhizophora apiculata) Silvia Rizkiani; Pambudi, Dwi Bagus; Urmatul Waznah; Achmad Vandian Nur
BENZENA Pharmaceutical Scientific Journal Vol 3 No 02 (2024): BENZENA PHARMACEUTICAL SCIENTIFIC JOURNAL
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/benzena.v3i02.5102

Abstract

Radikal bebas merupakan suatu senyawa reaktif baik atomik maupun molekuler yang memiliki satu bahkan lebih elektron yang tidak berpasangan. Radikal bebas akan mencari pasangan baru agar mudah bergabung dengan zat lain seperti lemak, protein dan DNA di dalam tubuh, hal ini dapat memicu kerusakan sel dan berbagai jenis penyakit degeneratif. Cara untuk mencegah radikal bebas yaitu dengan senyawa antioksidan. Senyawa Fenol dan flavonoid yang terdapat pada buah bakau minyak (Rhizophora apiculata) dapat digunakan sebagai penangkal radikal bebas. Tumbuhan ini memiliki kandungan metabolit sekunder berupa alkaloid, tanin, flavonoid, triterpenoid, steroid dan saponin. Tujuan penelitian adalah untuk mengetahui aktivitas antioksidan buah bakau minyak menggunakan metode FRAP. Untuk pengukuran aktivitas antioksidan menggunakan spektrofotometer UV-Vis Metode ekstraksi yang digunakan dalam penelitian ini adalah metode maserasi. Pelarut yang digunakan pada proses maseraasi adalah etanol 96%. Buah bakau minyak mempunyai aktivitas antioksidan Karenna memiliki kandungan metabolit sekunder fenol dan flavonoid. Berdasarkan hasil penelitian yang sudah dilakukan ekstrak buah bakau minyak mengandung kadar total fenol sebesar 139 mg GAE/g ekstrak, sedangkan kadar total flavonoid sebesar 19,6 mg QE/g ekstrak. Aktivitas antioksidan ekstrak buah bakau minyak diukur melalui spektrofotometer UV-Vis dengan panjang gelombang sebesar 596,5 nm. Hasil aktivitas antioksidan buah bakau minyak diperoleh sebesar 200,72 µmol/ Fe2+/g yang terdapat pada konsentrasi 100 µg/mL. Kata Kunci: Buah bakau minyak, Fenol, Flavonoid, Antioksidan
Optimalisasi Pemanfaatan Terapi Komplementer dalam Kehamilan Suparni, Suparni Bagus; Aisyah, Risqi Dewi; Pambudi, Dwi Bagus
Jurnal LINK Vol 21, No 1 (2025): MEI 2025
Publisher : Pusat Penelitian dan Pengabdian kepada Masyarakat, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/link.v21i1.12507

Abstract

Terapi komplementer adalah metode pengobatan yang tidak menggunakan obat-obatan konvensional dan dapat bermanfaat dalam mengatasi masalah kesehatan ibu hamil, seperti emesis gravidarum. Tinjauan literatur menunjukkan bahwa terapi komplementer dapat meningkatkan kesehatan fisik, psikologis, sosial, dan spiritual ibu hamil. Namun, perlu dipertimbangkan pula keamanan dan risiko penggunaan terapi komplementer pada ibu hamil. Kelas ibu hamil merupakan sarana yang penting untuk meningkatkan pengetahuan dan keterampilan ibu hamil tentang kehamilan, persalinan, dan perawatan bayi. Tujuan PKM ini adalah untuk mengoptimalkan pemanfaatan terapi komplementer dalam kehamilan di kelas ibu hamil di wilayah kerja Puskesmas Buaran Kabupaten Pekalongan. PKM dilakukan melalui penyuluhan kesehatan tentang terapi komplementer, demonstrasi praktik senam dan peregangan khusus untuk ibu hamil. Kegiatan dilaksanakan selama 3 bulan dengan melibatkan 51 ibu hamil di Posyandu. Hasil pengabdian menunjukkan adanya peningkatan yang signifikan dalam pengetahuan ibu hamil, dari nilai rata-rata 60,43 sebelum penyuluhan menjadi 81,54 setelah penyuluhan. Hal ini mengindikasikan bahwa metode penyuluhan yang digunakan efektif dalam meningkatkan pemahaman ibu hamil mengenai materi yang disampaikan. PKM ini berhasil meningkatkan pengetahuan ibu hamil tentang terapi komplementer dalam kehamilan, yang dapat membantu mereka mengatasi ketidaknyamanan selama masa kehamilan dengan lebih baik.
ANALISIS CEMARAN Escherichia coli DAN Salmonella typhi PADA JAMU GENDONG DENGAN METODE MOST PROBABLE NUMBER (MPN) Salsabila, Salma Fi; Rahmasari, Khusna Santika; Nur, Achmad Vandian; Pambudi, Dwi Bagus
Kartika : Jurnal Ilmiah Farmasi Vol 9 No 3 (2024)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v9i3.809

Abstract

The consumption of jamu kunyit asam and beras kencur is an integral part of Indonesian culture. Jamu kunyit asam, a mixture of turmeric and tamarind, is believed to enhance the immune system and aid digestion. Jamu beras kencur, made from rice and aromatic ginger, is known for boosting stamina and alleviating fatigue. However, the traditional production of jamu, often lacking strict hygiene standards, can lead to contamination by pathogenic microorganisms such as Escherichia coli and Salmonella typhi. This study aims to detect the presence of E. coli and S. typhi in jamu kunyit asam and beras kencur, and to analyze whether these traditional herbal drinks sold across districts in Pekalongan City comply with the established quality standards for traditional medicine. The analysis of pathogenic microorganisms using the Most Probable Number (MPN) method revealed that MPN values in the presumptive test using Lactose Broth and the confirmatory test using Brilliant Green Lactose Broth ranged from 0 to 18.98 MPN/mL. Out of four samples of jamu kunyit asam, one did not meet the permissible contamination limits, and three out of four samples of jamu beras kencur were non-compliant. The complementary tests showed that seven samples were positive for E. coli (samples coded A1, A2, B1, B2, C2, D1, and D2) and four samples were positive for S. typhi (samples coded A1, D1, C2, and D2).
Co-Authors Achmad Vandian Nur, Achmad Vandian Ainun Muthoharoh Ainun Muthoharoh, Ainun Attasih, Monicia Ayu Dyah Purwati Ayu, Roro B., Mahdanya Puteri A. Cahyaningrum, Galuh Surya Danang Raharjo Eko Mugiyanto, Eko Fika, Irma Firman Faradisi Fuad, Asfal Herni Rejeki Huda, Muhammad Syahrian Khoiriyah, Nisa'ul Kholidah, Nur Khusna Santika Rahmasari Maulidah, Lia Khusnul Mufidah, Nur Muhammad Sa'ad Muhtadi Ningrum, Wulan Agustin Nisa, Husna Idza Auziadzatun Novita, Helfi Nuniek Nizmah Fajriyah Nurul Aktifah, Nurul Qulub, Muhammad Syifaul Raharjo, Setyo Tri Rahman, Fadila Rahmatullah, ST. Risqi Dewi Aisyah Rosyada, Jihan Amrina S Slamet, S Safitri, Wiga Arum Safitri, Yuliana Nurul Salsabila, Salma Fi Sa’diyah, Aminatus Setianto, Gigih Silvia Rizkiani Siti Khuzaiyah, Siti Slamet , Slamet Slamet . Sulaiman, Naila Iva Amalina Putri Suparni, Suparni Bagus Sya'bania, Muti' Ulfa, Nadia Salsabila Urmatul Waznah Wirasti Wirasti, W Wirasti, Wirasti Yulian Wahyu Permadi