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All Journal Majalah Kedokteran Bandung ASPIRATOR Althea Medical Journal Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Global Medical and Health Communication Molecular and Cellular Biomedical Sciences (MCBS) Chimica et Natura Acta Jurnal Endurance: Kajian Ilmiah Problema Kesehatan BALABA (JURNAL LITBANG PENGENDALIAN PENYAKIT BERSUMBER BINATANG BANJARNEGARA) Jurnal Pengabdian Masyarakat (ABDIRA) Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)

Lia Faridah

Fakultas Kedokteran Universitas Padjadjaran

Author-ID : 532476

Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Mosquito Survey in the Campus Area of Universitas Padjadjaran Jatinangor in September to November 2016 Lia Faridah; Radiah Baizura; Sri Yusnita Irda Sari
Global Medical & Health Communication (GMHC) Vol 5, No 3 (2017)
Publisher : Universitas Islam Bandung

Sumedang regency reported being one of dengue endemic areas in West Java. The number of dengue fever patients in Sumedang District General Hospital increased in the last quarter of 2015. Universitas Padjadjaran (Unpad) is one of most significant areas in Jatinangor Sumedang where many people are doing their activity day and night. The purpose of the study was to identify what types of mosquito genera exist in Unpad campus according to the time and location. A field survey was conducted at 22 locations in Unpad campus using modified electric light trap placed indoor and outdoor at each site from September to November 2016. The modified electrical trap was turned on for 24 hours, and samples collected every 12 hours. Mosquitoes trapped were put into the plastic cup, labeled according to time collected, and brought to Parasitology Laboratory of Unpad for identification. The study result identified four types of mosquito genera which were Culex spp. (405), Armigeres spp. (70), Aedes spp. (33), and Anopheles spp. (10). Prevention toward potential breeding sites and protection using window net should be considered to reduce the risk of vector-borne diseases. In conclusion, Aedes spp. is the most active mosquito during the day while Culex spp. and Armigeres spp. are the most active mosquito during the night.SURVEI NYAMUK DI KAWASAN KAMPUS UNIVERSITAS PADJADJARAN JATINANGOR PADA BULAN SEPTEMBER–NOVEMBER 2016Kabupaten Sumedang dilaporkan sebagai salah satu daerah endemik demam berdarah di Jawa Barat. Jumlah pasien demam berdarah yang datang ke Rumah Sakit Umum Daerah Sumedang meningkat dalam tiga bulan terakhir pada tahun 2015. Universitas Padjadjaran (Unpad) merupakan salah satu wilayah yang terluas di Jatinangor Sumedang sebagai tempat banyak orang melakukan aktivitas pada siang dan malam hari. Tujuan penelitian ini adalah mengidentifikasi jenis genera nyamuk yang ada di kampus Unpad Jatinangor berdasar atas waktu dan lokasi. Survei lapangan dilakukan pada 22 lokasi di kampus Unpad Jatinangor pada bulan September–November 2016 menggunakan perangkap nyamuk cahaya yang dimodifikasi. Perangkap nyamuk ditempatkan di dalam dan luar ruangan untuk setiap lokasi. Perangkap nyamuk dipasang selama 24 jam, kemudian nyamuk dikumpulkan setiap 12 jam. Nyamuk yang terperangkap dikumpulkan dan dimasukkan ke dalam cangkir plastik, diberi label sesuai dengan waktu pengambilan, kemudian dibawa ke Laboratorium Parasitologi Unpad untuk diidentifikasi. Hasil penelitian menunjukkan 4 genera nyamuk ditemukan di kampus Unpad Jatinangor, yaitu Culex spp. (405), Armigeres spp. (70), Aedes spp. (33), dan Anopheles spp. (10). Pencegahan pada tempat yang berpotensi menjadi sarang nyamuk dan perlindungan menggunakan kawat nyamuk pada jendela harus dipertimbangkan untuk menurunkan risiko penyakit tular vektor. Simpulan penelitian ini, Aedes spp. merupakan nyamuk yang paling aktif pada siang hari serta Culex spp. dan Armigeres spp. yang paling aktif pada malam hari.

Upaya Pengendalian Aedes aegypti di Desa Cibeusi dan Cikeruh Kecamatan Jatinangor berdasar atas Populasi Nyamuk Lia Faridah; Cica Lavemita; Uun Sumardi; Nisa Fauziah; Dwi Agustian
Global Medical & Health Communication (GMHC) Vol 6, No 1 (2018)
Publisher : Universitas Islam Bandung

Masalah kesehatan masyarakat di Indonesia yang umum terjadi dalam beberapa tahun terakhir adalah penyakit demam berdarah dengue (DBD) yang ditularkan melalui gigitan nyamuk Aedes spp. Salah satu daerah endemis DBD adalah Kecamatan Jatinangor, kasus DBD tertinggi terjadi di Desa Cibeusi dan kasus terendah di Desa Cikeruh pada tahun 2014. Penelitian ini menggunakan rancangan potong lintang (cross sectional) dilaksanakan dari bulan September hingga November 2016. Teknik pengambilan sampel diambil secara sengaja (purposive sampling) dari dalam rumah di Desa Cibeusi dan Cikeruh. Setiap desa dipasang 10 perangkap nyamuk untuk 10 rumah meliputi luas wilayah 100×100 m2. Evaluasi hasil tangkapan dilakukan setiap 3 hari untuk setiap minggu selama 3 bulan. Data yang dicari adalah perbedaan jumlah nyamuk rata-rata dan upaya pengendalian Aedes aegypti di kedua desa. Data yang diperoleh dianalisis dengan uji t tidak berpasangan. Pada equal variance assumed, Sig. (2-tailed) sebesar 0,711 (p<0,05), hal tersebut menunjukkan bahwa jumlah nyamuk rata-rata di kedua desa tidak berbeda bermakna secara statistik pada probabilitas 0,05. Upaya pengendalian Aedes aegypti yang telah dilaksanakan di Desa Cibeusi pada tahun 2016 adalah larvasidasi, sementara Desa Cikeruh melaksanakan fogging. Simpulan, upaya pengendalian vektor yang dilaksanakan Puskesmas Jatinangor dalam menurunkan angka kejadian DBD masih kurang. ASSESSMENT OF AEDES AEGYPTI CONTROL EFFORT IN CIBEUSI AND CIKERUH VILLAGES JATINANGOR SUB-DISTRICT BASED ON THE POPULATION OF MOSQUITOThe dengue hemorrhagic fever (DHF) is a common public health problem in Indonesia over the past few years which is transmitted by the bite of Aedes spp. One of the DHF endemic area is the Jatinangor sub-district, in 2014 Cibeusi village that had the highest number of DHF cases whereas the lowest number was recorded in Cikeruh village. This study used cross sectional design and it was conducted from September until November 2016. The sampling technique was purposive sampling from the residencies in Cibeusi and Cikeruh village. Each village was set up 10 mosquito traps for 10 houses covering an area 100×100 m2. Evaluation of the catches was done every 3 days per week for 3 months. Data to be found is the difference in mean number of mosquitoes and Aedes aegypti control efforts in both villages. The data collected was analyzed with unpaired t-test. Sig. (2-tailed) value at equal variance assumed was 0.711 (p<0.05), this showed that there was no statistically significant difference in the mean number of Aedes aegypti or it is not significant at 0.05 probability in both villages. Aedes aegypti control efforts on 2016 which have been held in Cibeusi village was larvaciding, while fogging activities in Cikeruh village as a control efforts. In conclusion, there is still lacking of vector control efforts undertaken by Jatinangor Public Health Center in reducing DHF incidence.

Effectiveness of Various Mosquito Attractant Solutions to Control Mosquito Population Faridah, Lia; Albert, Christian; Fauziah, Nisa
Global Medical & Health Communication (GMHC) Vol 7, No 1 (2019)
Publisher : Universitas Islam Bandung

The vector-borne disease is a disease caused by an organism that can transmit disease between human or animal to human. In Indonesia, several vector-borne diseases are a burden of the government including dengue fever, chikungunya, filariasis, and malaria. The attractive baited lethal ovitrap (ALOT) is a novel strategy to alleviate mosquito populations in three main actions: attraction, an adulticide, and larvacide. Research using plant infusion can attract mosquitoes to lay their eggs is needed. This study aims to compare the effectiveness of the mosquito repellent solution using materials from organic waste in Bandung. This study was a quantitative analytic study with a quasi-experimental design conducted in the Faculty of Medicine Universitas Padjadjaran area in October 2016–July 2017. Research subjects are mosquito eggs in a solution which placed at 25 different places for every solution. The analysis was performed using Kruskal-Wallis test followed by the Dunn test. The result of the Kruskal-Wallis test indicates the difference of effectiveness of each solution (p<0.05). Based on the results of the Dunn test, the most significant difference found in the solution of wood shavings with the vegetable waste solution and the solution of wood shavings with corn straw (p<0.05). In conclusion, there is a difference in the effectiveness of the mosquito repellent solutions and the most attractive solution for mosquitoes to oviposit is the corn straw solution. EFEKTIVITAS BERBAGAI LARUTAN PENARIK NYAMUK UNTUK MENGONTROL POPULASI NYAMUKPenyakit tular vektor adalah penyakit yang disebabkan oleh organisme yang dapat mentransmisikan penyakit antarmanusia atau hewan ke manusia. Di Indonesia, terdapat beberapa penyakit tular vektor yang masih menjadi beban pemerintah, di antaranya demam berdarah, chikungunya, penyakit kaki gajah, dan malaria. Attractive baited lethal ovitrap (ALOT) merupakan strategi baru untuk menurunkan populasi nyamuk dalam tiga aksi utama, yaitu attraction, adulticide, dan larvacide. Penelitian terkait larutan dari tanaman yang dapat menarik nyamuk sangat diperlukan. Penelitian ini bertujuan membandingkan efektivitas larutan penarik nyamuk dengan menggunakan bahan dari limbah organik yang ada di Kota Bandung. Penelitian ini adalah penelitian analitik kuantitatif dengan desain quasi-eksperimental yang dilakukan di lingkungan Fakultas Kedokteran Universitas Padjadjaran pada bulan Oktober 2016–Juli 2017. Subjek penelitian merupakan telur nyamuk yang ada pada larutan yang diletakkan pada 25 titik untuk setiap larutan. Analisis dengan Uji Kruskal-Wallis yang dilanjutkan dengan Uji Dunn. Hasil penelitian dengan Uji Kruskal-Wallis menunjukkan perbedaan efektivitas tiap-tiap larutan (p<0,05). Berdasar atas hasil Uji Dunn, perbedaan yang paling signifikan terdapat pada larutan serutan kayu dengan larutan sampah sayur dan larutan serutan kayu dengan jerami jagung (p<0,05). Simpulan, terdapat perbedaan efektivitas larutan penarik nyamuk dan larutan yang menarik nyamuk paling banyak untuk bertelur adalah larutan jerami jagung.

Arbovirus Detection of Adult Female Aedes aegypti for Dengue Surveillance: a Cohort Study in Bandung City, Indonesia Faridah, Lia; Ekawardhani, Savira; Fauziah, Nisa; Djati, Imam Damar; Putra, Ramadhani Eka; Watanabe, Kozo
Global Medical & Health Communication (GMHC) Vol 11, No 3 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i3.12749

Dengue surveillance is an important activity to prevent dengue outbreaks. This activity becomes a significant challenge for the region with limited logistic capabilities. Developing a simple mathematical model to predict the possibility of dengue incidence provides a reliable early warning system. This study compared the correlation between vector (adult female Aedes aegypti) and arbovirus detection on a vector to dengue incidence, which generalized linear mixed models tested. The incidence of adult female Aedes aegypti and dengue fever cases were interpolated through third-power inverse distance weighting (IDW). A spatial correlation between female Aedes aegypti incidence and dengue incidence was obtained from polynomial regression. Collection sites were 16 villages in Bandung city, one of the significant dengue endemic areas in January–December 2017. A total of 8,402 mosquitoes of Aedes aegypti, Aedes albopictus, and Culex sp., with 17% belonging to Aedes aegypti as the subject of the dengue virus (DENV) infection test. Data analysis only showed a weak correlation between the numbers of adult female Aedes aegypti and dengue incidence. On the other hand, there is no correlation between positive dengue infection of vector and dengue incidence. This study highlights the importance of constant arbovirus surveillance and integrated surveillance methods on all possible dengue vectors to develop an early warning system for dengue incidence.

Stakeholder Insights on Malaria Elimination Strategies in Pangandaran, West Java: a Qualitative Analysis Faridah, Lia; Fauziah, Nisa; Adams, Fayyaza Faiz; Mufida, Hasna; Akbar, Muhamad Lazuardi; Salsabila, Pricillia Laurenza; Rufinus, Wilbert Bernardi; Virajati, Abimanyu Athallah; Angga, Anggisti Nurdinda Chaerany Putri; Mahira, Khansa; Zahra, Ridha Beta
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13483

Indonesia has launched a determined effort to eliminate malaria by 2023, focusing on Java and Bali. Despite these efforts, Pangandaran in Java still faces malaria cases. This study aims to meticulously delve into the intricacies of the malaria elimination program's implementation while conducting a comprehensive evaluation of its effectiveness. Structured interviews were conducted with key stakeholders responsible for the malaria program in Pangandaran to extract invaluable insights. The study, carried out in November 2022, followed qualitative research with narrative analysis to reveal nuanced narratives from the participants. Findings from this rigorous analysis revealed a harmonious alignment between the malaria control program in Pangandaran and the Indonesian Ministry of Health guidelines. The strategy to combat malaria vectors in Pangandaran included mosquito net distribution, strategic larvicide application, and educational campaigns like Malaria Awareness Society (MASAMA). The expectation is that the current effective control program will resonate within the Pangandaran community, ultimately leading to the realization of the 2023 elimination target.

Cytotoxicity Effect of Aqueous Propolis Extract of Geniotrigona thoracica Sumatrans on Colo-201 Colon Cancer Cell Line and Senescence Colo-201 Colon Cancer Cell Line Induced by Low-dose Doxorubicin Latama, Zahra Nabila; Achadiyani, Achadiyani; Kamilah, Mutiara Mila; Putra, Ramadhani Eka; Kinasih, Ida; Faridah, Lia; Ekawardhani, Savira
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13760

Propolis, a resinous compound honeybees produce, demonstrates an extensive spectrum of powerful biological properties. However, the anti-cancer activity of propolis derived from Geniotrigona thoracica Sumatrans has yet to be reported. Thus, we sought to investigate the cytotoxicity of aqueous propolis extracts from Geniotrigona thoracica Sumatrans against Colo-201 colon cancer cell line and senescence Colo-201 colon cancer cell line induced by low-dose doxorubicin. This study was conducted at the Parasitology Laboratory of Human, Safety, and Environment, Universitas Padjadjaran Bandung from January to May 2024. This study assessed cell viability using the WST-1 test. Non-induced Colo-201 cells were treated with an aqueous extract of propolis (AEP) 100 ppm, or 5-fluorouracil (5-FU) 5 mg/ml as the positive control or water as a vehicle on untreated control. Colo-201 senescence was induced by doxorubicin 0.1 µM for three days. Doxorubicin-induced Colo-201 senescence was then treated with AEP 100 ppm, with 5-FU 5 mg/ml as the positive control, or with the combination of AEP 100 ppm and 5-FU 5 mg/ml, or water as a vehicle on untreated control. The data were analyzed using SPSS version 25.0, a one-way ANOVA, and Tukey’s post hoc test. The results showed that AEP has cancer-killing effects on Colo-201 cells and Colo-201 senescent cells induced by low-dose doxorubicin. AEP-treated Colo-201 cells and Colo-201 senescent cells induced by low-dose doxorubicin viability were significantly reduced to 37.15% and 13.72%, respectively, although slightly higher than those of the 5-FU-treated one at this concentration. There was also a decrease in the cancer-killing effect of 5-FU from 88.55% in non-induced Colo-201 cells to 41.5% in the doxorubicin-induced Colo-201 senescence model. In conclusion, aqueous extract of propolis from Geniotrigona thoracica Sumatrans showed cancer-killing-effects both on the Colo-201 colon cancer cell line and senescence Colo-201 colon cancer cell line induced by low-dose doxorubicin.

Promotion of Crypt-like Structures in Intestinal Organoid Development through the Addition of Graphene Oxide in Cell-based Assays Sulaksono, Haura Labibah Salsabil; Kamilah, Mutiara Mila; Faridah, Lia; Joni, I Made; Watanabe, Kozo; Ekawardhani, Savira
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.13386

The intestinal organoid represents a miniature organ that can mimic functional physiology and pathology. However, there are several challenges to developing the organoid system, such as the limited survival of cells. Based on theory, matrix addition is a factor that can support survival in cells. As a result, graphene oxide (GO) addition is used in this study. As an artificial matrix, GO has been successfully shown to encourage good cell behavior and is well known for having good biocompatibility. Herein, we fabricate GO characterized with FT-IR and PSA. Crypt-like structures (CLS) are isolated from small intestinal mice in GO addition as a matrix. The gene expression and cell viability of CLS are investigated. RT-PCR examined the gene expression in CLS, while cell viability of CLS was carried out using the staining method. This study was conducted at FiNder U-CoE and Parasitology Laboratory of HSE Universitas Padjadjaran Bandung during February and December 2023. Our results show that Vil-1 as an identity for cells in the intestinal epithelium has been expressed in CLS primary significantly higher than intestinal tissue (p=0.01). However, identifying Lgr5 in CSL isolates is tricky. Thes in the crypt may be limited. Besides that, cell viability of CLS with GO addition can be maintained for four days. The GO addition as a matrix may provide support to maintain CLS. These findings are promising as cell-based assays for developing organoid models.

Community Participation and Mosquito Breeding Sites in Cimahi City: Current Conditions and Challenges in Dengue Fever Control Faridah, Lia; Angga, Anggisti Nurdinda Chaerany Putri; Fauziah, Nisa; Jaya, I Gede Nyoman Mindra
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14241

In 2021, Cimahi City recorded the 5th highest dengue fever (DF) cases among 27 districts/cities in West Java. Efforts to control DF have been going on for several decades, with one strategy being to involve community participation in eliminating mosquito breeding sites. This research evaluated community participation in Cimahi city by identifying mosquito breeding locations inside and outside the home. Samples were taken from 15 sub-districts in Cimahi city. The research population involved houses in 15 sub-districts, with a total sample of 1,560 houses representing each sub-district. Larval sampling was carried out in various water reservoirs, both natural and artificial, around residential areas. The successfully taken larvae were then identified and counted in the laboratory. The research showed that the most dominant mosquito breeding place was in bucket-type containers, namely 130 units (3.2%). Entomological data produced a free larva index (FLI) of 79.23%, a house index (HI) of 20.7%, a container index (CI) of 8.07%, and a Breteau index (BI) of 20.5%. This finding indicated a lack of community involvement in preventing vector-borne diseases by eliminating breeding sites. Cimahi city still had the potential to spread vector-borne diseases.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14138

Co-Authors Achadiyani Adams, Fayyaza Faiz Adelina Siagian Adrizain, Riyadi Agnes Kurniawan Agoes, Ridad Agrianfanny, Yukan Niko Ainul Yaqin Akbar, Muhamad Lazuardi Albert, Christian Amirul Mukminin Angga, Anggisti Nurdinda Chaerany Putri Ardini Raksanegara Arie Galih Mohamad Asep Sofyan Astri Gloria Larwuy Bashari, Muhammad Hasan Chin Annrie Eidwina Chin Annrie Eidwina, Chin Annrie Cica Lavemita Dicky Bagus Pratama Dida Akhmad Gurnida Dida Akhmad Gurnida, Dida Dini Oktaviani Djati, Imam Damar Dwi Agustian Dwi Agustian Elsa, Zahratul Eva Nuriyah, Eva Fahmy Fathurrohman Fauzah, Nisa Fauziah, Nisa Fauziah, Nisa Gaga Irawan Nugraha H. Uun Sumardi H. Uun Sumardi, H. Uun Hadyana Sukandar Hadyana Sukandar Hakiki, Nadhira Permata Hamda, Muhammad Ersyad Hazel Faras Alhafiz Heni Djuhaeni Hesti Lina Wiraswati I Gede Nyoman Mindra Jaya I Made Joni Ida Kinasih Ika Puspa Sari Ita Krissanti Jontari Hutagalung Jontari Hutagalung Kamilah, Mutiara Mila Khotibul Umam Komathi Palani Komathi Palani, Komathi Latama, Zahra Nabila Leonita, Inggrid Mahira, Khansa Meita Dhamayanti Meita Dhamayanti Meri Alex Sandra Mufida, Hasna Muhammad Ersyad Hamda Muhammad Saifuddin B. S. Arif Nadhira Permata Hakiki Naufal Fakhri Nugraha Naufal Fakhri Nugraha Neneng Syarifah Syafei, Neneng Syarifah Nisa Fauziah Octoviani, Fanny Anggraeni PUTRI, RAFIKA Radiah Baizura Ramadhani Eka Putra raudatul jannah Reyhan Luthfierza Fauzan Riyadi Adrizain Rufinus, Wilbert Bernardi Safri Ishmayana Salma Nur Raidah Salsabila, Pricillia Laurenza Sarasati Windria Savira Ekawardhani Shabarni Gaffar -, Shabarni Gaffar Shabrinna, Hanif Sri Yusnita Irda Sari Sri Yusnita Irda Sari, Sri Yusnita Irda Sulaksono, Haura Labibah Salsabil Sunarjati Sudigdoadi Syafrizal Saragih Titik Respati Uun Sumardi Uun Sumardi, Uun Virajati, Abimanyu Athallah Watanabe, Kozo Yasfira Aradella Yeni Wahyuni Hartati Yudith Setiati Ermaya Yuliarni, Dinda Zahra, Ridha Beta Zahratul Elsa

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