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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Health Notions Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Biomolecular and Health Science Journal Cermin Dunia Kedokteran Cermin Dunia Kedokteran Folia Medica Indonesiana
Trisniartami Setyaningrum
Departemen/ SMF Ilmu Kesehatan Kulit Dan Kelamin, Fakultas Kedokteran Universitas Airlangga/ RSU Dr. Soetomo, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Biomolecular and Health Science Journal

 1 
Distribution Genotype High Risk (HR) And Low Risk (LR) Human Papillomavirus (HPV) at Condyloma Acuminata Gondo Mastutik; Alphania Rahniayu; Dwi Murtiastutik; Afria Arista; Trisniartami Setyaningrum; Nabiha Missaoui; Suhartono Taat Putra
Biomolecular and Health Science Journal Vol. 4 No. 1 (2021): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v4i1.26250

Abstract

Introduction: Condyloma acuminata that is also known as genital warts are one of the most common sexually transmitted that caused by infection of Human papillomavirus (HPV). Persistent infection of Low Risk (LR) or High risk (HR) HPV is a risk factor for progress into benign or malignant cancer. The objective is to analyze distribution of genotype LR-HPV and HR-HPV at condyloma acuminata in anogenital region. Methods: A cross sectional study using were 36 lesions from men and women of condyloma acuminata patients. All subject signed the informed consent and ethic obtained from our institution, number 382/Panke.KKE/V/2016. The specimen was used to histopathological examination and to identified 40 genotypes of HPV using a reverse line blot assay.Results: The All patients were diagnosed as condyloma acuminata, some with focus dysplasia and koilocytosis. All patients were positive for HPV, including LR-HPV were HPV 6, 11, 42, 54, 61, 81,87,89 and HR-HPV were HPV 18, 26, 45, 51, 52, 66, 67, 68B, 69, 82. The single infection of LR-HPV was 44.4%, multiple infection LR/LR-HPV was 13,9% and the multiple infection of LR/HR-HPV was 41.7%. The LR-HPV infected 70,6% and HR-HPV infected 29,4%.  Conclusion: LR-HPV is the major infection of condyloma acuminata, in single infection or multiple infection with HR-HPV. The most common infections were HPV 11, followed by HPV 6, HPV 18, HPV 51, and HPV 82. The determination of genotype of HPV can be used to predict the malignant transformation.
Co-Authors Abdul Karim Ade Fernandes Afif Nurul Hidayati, Afif Nurul Afria Arista Afria Arista Afria Arista, Afria Agatha Anindhita Ayu Ardhaninggar Alarik L., Albertus Alphania Rahniayu Amanda Gracia Manuputty Amira Suryani Rahmatika Anggraeni, Sylvia Arifa Mustika Artaria Tjempakasari, Artaria Asrianti, Nur Ilma Astindari Astindari Astindari Astindari Astindari Astindari, Astindari Aulia Rafikasari Axelia, Presstisa Gifta Bagus Haryo Kusumaputra, Bagus Haryo Budiono Budiono Christina Avanti Cita Rosita Sigit Prakoeswa Cita Rosita SP Damayanti Damayanti - Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Deasy Fetarayani Diah Mira Indramaya Dinar Witasari Dwi Murtiastutik Dyah Ratri Anggarini Dyah Ratri Anggarini, Dyah Ratri Eden Leonita Eva Lydiawati Evy Ervianti Febrina Dewi Pratiwi Gondo Mastutik Hadiwidjaja, Farsha Naufal Hans Lumintang Hans Lumintang, Hans Lumintang,, Hans Hari Sukanto, Hari Hening Laswati Putra Indiastuti, Danti Nur Irmadita Citrashanty Irmadita Citrashanty, Irmadita Irwadi, Irfiansyah Iskandar Zulkarnain Kathrin Kezia Henry Koesandrini, Kinanthi KUSUMASTUTI, ETTY HARY Linda Astari, Linda LINGGA, FEBRINA DEWI PRATIWI Lisa Aditama, Lisa Lutfia Ariska Ramadhani M. Yulianto Listiawan Mappamasing, Hasnikmah Marsudi Hutomo Marsudi Hutomo, Marsudi Maylita Sari Maylita Sari, Maylita Medhi Denisa Alinda, Medhi Denisa Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati, Menul Ayu Nabiha Missaoui Ngesti Kumalasari, Diah Puspowati, Erindah Putri Brillian Betrista Viorizka Qurnianingsih, Ema Rahmadewi Rahmadewi Rahmadewi Rahmatika, Amira Suryani Ramadhina, Anasya Putri Renata Mayangsari Ridha Ramadina Widiatma Riezky Januar Pramitha Rozita Maharani, Dinda Ryski Meilia Novarina Ryski Meilia Novarina Ryski Meilia Novarina, Ryski Meilia Samsriyaningsih Handayani Sawitri Sawitri Sawitri Sawitri Shakti Indraprasta Shakti Indraprasta, Shakti Shelma Maharani Shinta Dewi Rahmadhani Soetojo Suhartono Taat Putra Sulaksanaswastho Suyoso Sunarto, Olivia Awwalin Susanto, Ester Chateline Tasya Wikassa Tengku Riza Zarzani N Widyantari, Septiana Willy Sandhika Yasmin Adzra Nabila Yosi Charly Yuani Setiawati Yuli Wahyu Rahmawati Yuri Widia, Yuri Zada Febrial Effendy Zada Febrial Effendy, Zada Febrial