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URINARY TRACT INFECTION WITH STUNTING AND NON-STUNTING IN RURAL AREA PANDEGLANG, BANTEN, INDONESIA 2021 Wan Nedra; Yulia Suciati; Muhammad Arsyad; Sarah Kemalasari; Khansadhia Hasmaradana Moiindie; Mochamad Alif Ariesando; Nabila Wahyu Salsabilla; Adifa Mazdalifah
Medical Journal of Nusantara Vol. 2 No. 1 (2023): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v2i1.57

Abstract

Urinary Tract Infections (UTIs) are bacterial infection that often occurs in childhood. Its occurrence depends on several predisposing factors and individual immunocompetence. Children with stunting have impaired immune function; therefore, early detection and prompt treatment of associated infections in children with stunting are critical. This study aimed to identify the association between UTI incidence in stunting and non-stunting children in Banten. This cross-sectional study was conducted in Pandeglang Regency, Banten. The subject of this study was 120 children aged 6 to 72 months. Well-nourished children matched for age were selected for the control group. Data was collected by a questionnaire-guided interview, physical examination, and urinalysis examination. Out of 120 respondents, 72 respondents (60%) were categorized as stunting and 26 respondents (21,67%) had UTIs. Out of the respondents who experienced UTIs, 15 respondents (12.5%) were categorized as severely stunted, and 5 respondents (4.17%) were categorized as stunted. There is an association between UTI and stunting.
Nicotine reduces cell viability and induces oxidative stress in human gingival fibroblasts Azmi, Sabrina; Hadi, Restu Syamsul; Kusuma, Indra; Suciati, Yulia; Sari, Wening
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.20-30

Abstract

BackgroundNicotine, as the main component of cigarettes, is known to interfere with the proliferation of human gingival fibroblasts (HGFs) and can trigger oxidative stress. This study aimed to analyze the impact of nicotine on viability, expression of the antioxidant Nrf2, levels of the product of oxidative stress malondialdehyde (MDA), and the migration capacity of HGFs. MethodsAn experimental laboratory study used fibroblasts isolated from healthy human gingiva. The cells were grouped into the non-treatment control group (NTC), the solvent control (SC), and the treatment groups, exposed to nicotine at various concentrations for twenty-four hours. Cell viability was assesed using the cell counting kit-8 (CCK-8), Nrf2 expression was examined using ELISA, MDA level was measured using an MDA kit, and migration capacity was assessed using a scratch assay. Statistical analysis used one-way Anova or Kruskal-Wallis test. A p-value of <0.05 was expressed statistically significant. ResultsThe Cell viability was substantially reduced in the nicotine group compared to the untreated group, accompanied by changes in cell morphology. In contrast, Nrf2 expression increased significantly (p=0.010) in the 5 mM nicotine group compared with the control group. The MDA levels were not significantly distinct across groups (p=0.056). Cell migration was delayed significantly in the 5 mM nicotine group at 72 hours after scratching compared to the control group. ConclusionNicotine decreased HGFs viability and increased Nrf2 expression significantly in a dose-dependent manner. Nicotine at 5 mM concentration did not alter MDA levels but delayed cell migration.
Evaluation of Mortality Risk Factors of COVID-19 in Jakarta Tertiary Hospital During Peak of Second Wave and Predictive Utility of Community RT-PCR Low CT Values Putra, Andika Chandra; Burhan, Erlina; Aufa, Akhdan; Bur, Rika; Pangestu, Hendri; Bahri, Syukrini; Souvriyanti, Elsye; Muchtiar, Mulyadi; Erlina, Andi; Aditama, Tjandra Yoga; Yuliwulandari, Rika; Kusuma, Indra; Suciati, Yulia; Rifqatussaadah, Rifqatussaadah; Jalal, Fasli; Gusnanto, Arief; Utomo, Ahmad Rusdan H
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.133

Abstract

Background: The Delta variant of SARS-CoV-2 led to a surge in COVID-19 cases in Indonesia. This study aimed to assess the demographic profile and mortality rates of hospitalized COVID-19 patients in YARSI referral hospital, Jakarta, comparing pre-Delta and Delta wave periods. The study also investigated whether low CT values in RT-PCR tests indicated heightened viral transmission before the Delta wave surge. Method: A retrospective analysis was conducted on 1,457 COVID-19 patients hospitalized at YARSI (January-August 2021) and 25,279 RT-PCR test results from walk-in patients (April-August 17, 2021). Differences were evaluated using Chi-square or Fisher’s Exact Tests while binary logistic regression was used to assess mortality risk factors. Results: There were increased proportions of pregnant women, patients aged 20-29 and those with coronary artery disease during the Delta wave. This period also showed a significant increase in mortality rates, with the highest seen in patients >60 years old or those with multiple comorbidities. Notably, most of the deceased patients (131 of 139) were unvaccinated. Analysis of RT-PCR data showed rising percentages of positive results with low CT values (below 21 or 15) from April to June. Conclusion: The Delta wave saw a higher risk of hospitalization among young individuals and pregnant women, despite their low mortality risk. The unvaccinated and those with multiple comorbidities faced higher mortality risks. Increases in RT-PCR positivity with low CT values preceded the July COVID-19 case surge.
Kandungan Pewarna Rhodamin B Pada Kerupuk Berwarna Merah yang Beredar di Pasar Tradisional Rawasari Cempaka Putih dan Tinjauannya dalam Pandangan Islam Khairunnisa, Aqillah Munawwarah; Suciati, Yulia; Suseno, Dedy; Roswiem, Anna P.; Qomariyah, Qomariyah; Arsyad, Muhammad
Cerdika: Jurnal Ilmiah Indonesia Vol. 2 No. 9 (2022): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/cerdika.v2i9.428

Abstract

Rhodamin B merupakan zat pewarna berupa kristal yang tidak berbau dan berwarna hijau atau ungu kemerahan yang beredar di pasar untuk industri sebagai zat pewarna tekstil. Tujuan dari penelitian ini ialah untuk mengetahui dan mengidentifikasi ada atau tidaknya zat pewarna sintetis Rhodamin B pada kerupuk berwarna merah yang beredar di Pasar Tradisional Rawasari Cempaka Putih. Penelitian bersifat eksperimental dengan melakukan uji laboratorium secara kualitatif dengan metode kromatofrafi lapis tipis dan uji kuantitatif dengan metode spektrofotometri UV Vis. Pengambilan sampel menggunakan teknik berupa Random Sampling, yaitu cara pengambilan sampel secara acak di Pasar tradisional Rawasari Cempaka Putih. Terdapat kandungan zat pewarna sintetis Rhodamin B pada salah satu sampel kerupuk berwarna merah yang beredar di Pasar Tradisional Rawasari Cempaka Putih.
Kandungan Pewarna Rhodamin B Pada Saus Sambal Dalam Kemasan yang Beredar di Pasar Tradisional Rawasari Cempaka Putih dan Tinjauannya Menurut Pandangan Islam Salsabila, Dindana Caesarea; Suciati, Yulia; Suseno, Dedy; Roswiem, Anna P.; Qomariyah, Qomariyah; Arsyad, Muhammad
Cerdika: Jurnal Ilmiah Indonesia Vol. 2 No. 10 (2022): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/cerdika.v2i10.429

Abstract

The content of harmful dyes such as Rhodamine B in food, especially chili sauce in packaging, can be dangerous. The purpose of this study was to determine and identify the presence or absence of synthetic dye Rhodamin B in packaged chili sauce circulating in the Rawasari Cempaka Putih Traditional Market. This research is an experimental research, namely by conducting qualitative laboratory tests with thin layer chromatography and quantitative with UV-vis spectrophotometer to analyze the presence of Rhodamine B in packaged chili sauce sold in the traditional market of Rawasari Cempaka Putih. The samples used in this study were all types of packaged chili sauce which had striking red color characteristics and were taken randomly from the survey results at the Rawasari Cempaka Putih traditional market with a random sampling determination of the sample. The results showed that the five samples of packaged chili sauce sold at Pasar Rawasari Cempaka Putih had final results which stated that Rhodamine B dye was not detected.