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The Effect of Corticosteroid Administration on Maternal Outcomes in Patients with Hellp Syndrome Yulistiani, Yulistiani; Rana, Rana
Eduvest - Journal of Universal Studies Vol. 4 No. 6 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i6.1480

Abstract

HELLP syndrome is a hemolysis syndrome with microangiopathic blood smears, increased liver enzymes, and low platelets in pregnant and postpartum patients. HELLP syndrome may be a complication or progression of severe preeclampsia. The death rate due to HELLP syndrome is relatively high. The use of corticosteroids is expected to increase platelet counts, reduce LDH values, and reduce liver function parameters to speed up the duration of healing and reduce mortality. Corticosteroids inhibit endothelial activation, reduce vascular endothelial injury, increase hepatic blood flow, prevent thrombotic microvascular hemolysis, and reduce platelet consumption. Objective: To evaluate the effectiveness of corticosteroids in patients with HELLP syndrome. Method: This research was conducted using a literature review method by searching articles from Google Scholar, PubMed, and Science Direct. Results: Administration of corticosteroids can increase platelet counts, reduce AST/ALT values, and reduce the need for blood product transfusions. Conclusion: Corticosteroids effectively increase platelet counts in patients with HELLP syndrome.
The Efficacy of Pharmacological and Non-Pharmacological Therapy In Thyroid Storm Patients With Cardiovascular Complications : Literature review Amir, Nur Rezky Rutami; Yulistiani, Yulistiani
Malahayati Nursing Journal Vol 7, No 5 (2025): Volume 7 Nomor 5 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i5.18694

Abstract

ABSTRACT Tyroid storm is a life-threatening with clinical manifestation of thyrotoxicosis can cause other organ dysfuntion such as cardiovascular disorders. Therefore, eary detection using Burch and Wartofsky Point Scale that treatment can be optimally. The purpose of literature review is examine the treatment used thyroid storm with cardiovascular complications and the effectiveness of therapy achieve eutiroid. The research use a qualitative method with a literature review design. Data collected from article, journal using keywords and based on inclusion criteria been used Google Scholar and Science Direct databases. The results of journal screening is five journal with case report design. Pharmacological treatment use thionamides, beta blockers, corticosteroids, and potassium iodide, The efficacy  of therapy depending on the patients complications. Non-Pharmacological therapy plasmapheresis, is used if the patient  is given pharmacological therapy and does not show a response after 48 hours of administration. The efficacy of plasmapheresis shows improved clinical effect and euthyroid state. Keywords: Thyroid storm, Pharmacological, Non-Pharmacological, Eutiroid