Article Per Year (5 Year)
p-Index From 2021 - 2026
2.63
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Molecular and Cellular Biomedical Sciences (MCBS) Smart Medical Journal Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Jurnal Mandala Pharmacon Indonesia BERDAYA: Jurnal Pendidikan dan Pengabdian Kepada Masyarakat International Journal of Applied Technology Research Tri Dharma Mandiri: Diseminasi dan Hilirisasi Riset Kepada Masyarakat (Jurnal Pengabdian Kepada Masyarakat) TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora International Journal of Economics (IJEC) Sciences of Pharmacy Eduvest - Journal of Universal Studies Riwayat: Educational Journal of History and Humanities Jurnal Informatika: Jurnal Pengembangan IT Folia Medica Indonesiana
Yulistiani Yulistiani, Yulistiani
Mahasiswa Jurusan Perencanaan Wilayah dan Kota, Fakultas Teknik, Universitas Diponegoro
Aerospace Engineering Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences Other

Published : 32 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 32 Documents
Search

 1   2   3   4 
Phosphatidylglycerol study as fetal lung maturation parameter after dexamethasone administration for women at risk of preterm birth Rahmadani, Rizal Umar; Sulistyono, Agus; Yulistiani, Yulistiani; Yahya, Muhammad
Folia Medica Indonesiana Vol. 52, No. 4
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Phosphatidylglycerol is an important indicator of fetal lung maturation, which plays a role in stabilizing surfactant lipoprotein complex. Corticosteroid antenatal can stimulate the synthesis of pulmonary surfactant in infants with preterm birth. The objective of this study is to examine the phosphatidylglycerol levels as fetal lung maturation parameter after dexamethasone administration in women with preterm birth compared to L/S ratio parameter. This study was prospective longitudinal (cohort). The samples were pregnant women with preterm birth risk at 28-34 weeks gestation getting the therapy of antenatal dexamethasone 6 mg IM every 12 hours given 4 times in 48 hours. The samples were 17 patients. Determination of L/S ratio and PG levels was performed by ELISA. The study was conducted from May - November 2015 and reviewed to obtain ethics eligibility permit by the research ethic committees of Dr. Soetomo General Hospital. The results show that the mean value of L/S ratio is 2.28 with a range of 1.35 to 9.06 and the mean of PG level is 1.17 with a range from 0 to 3.79. L/S ratio and PG show no significant relationship between the two of them. Increased levels of PG on the gestational age of 28-32 weeks have not demonstrated clinically significant changes yet. The highest PG level occurs in the gestational age of 32-34 weeks.
Children with Standard Risk Acute Lymphoblastic Leukemia in Induction And Consolidation Phase Amarullah, Adinugraha; Hasmono, Didik; Ugrasena, IGD; Yulistiani, Yulistiani
Folia Medica Indonesiana Vol. 54, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Prednisone has an important role in the therapy of patient with standard risk ALL. Patients with standard risk ALL receiving high dose prednisone as therapy and supraphysiology dose of prednisone are expected to cause suppression in HPA-axis (Hypothalamic Pituitary Adrenal axis). This suppression could reduce immune system in children with ALL and increase infection risk because reduction of cortisol level. In Indonesia, we did not find study about the incident of adrenal suppression after high dose prednisone therapy, especially in induction to consolidation phase ALL patient. The aim of this study was to analyze adrenal suppression after high dose prednisone therapy on children with standard risk acute lymphoblastic leukemia in induction and consolidation phase. This study has received a certificate of Ethical Clearance No. 588/Panke.KKE/X/2016, a longitudinal observational, prospective, non-randomized trial involving children with ALL who received prednisone for 49 days during the induction phase. We collected and compared laboratory result of cortisol level in children with ALL and received prednisone therapy during induction to consolidation phase. Sample was taken at week 0,4,5,6,7,8,10,12 in the course of ALL chemotheraphy Indonesian protocol year 2013. Serum was examined using methods CLIA ADVIA Centaur® XP. Between June 2016 – January 2017, 13 patients (8 males, 5 females) were included in this study. Decrease of cortisol level after prednisone therapy occured in week-10 as much as 53% compared with week-0 (p=0.027). Cortisol level increased 64% of week-12 compared with week-10 (p=0.003). In conclusion, high dose prednisone is not significant to causing adrenal suppression in induction phase of ALL patients, and the reducing cortisol level is reversible.
Analysis of Methyldopa Therapy on sFlt-1 Antiangiogenic Levels in Patients with Severe Preeclampsia Herwati, Teri Wina; Yulistiani, Yulistiani; M, Eddy Zarkaty
Folia Medica Indonesiana Vol. 54, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Methyldopa is the first-line drugs to treat hypertension in pregnancy. It can decrease blood pressure in preeclampsia by affecting a2-adrenoreceptors in central nervous system. However, it could also act by decreasing production of sFlt-1 antiangiogenic protein levels involved in the pathophysiology of hypertention in preeclampsia. The purpose of this study was to analyze methyldopa therapy on sFlt-1 antiangiogenic levels in the plasma of pregnant women with severe preeclampsia at the Obstetric Departement, Haji Hospital, Surabaya. This was a prospective study with observational cross-section study design. The sFlt-1 angiogenic levels were observed before and after (48 hours) methyldopa administration in severe preeclampsia patient with or without complications in the period of August to October 2016. Patient received methyldopa 250 mg or 500 mg, three times a day for clinical indications according a standard protocol. The study was approved by the ethical committee of Haji Hospital, Surabaya. There were 19 patients with preeclampsia who met the inclusion criteria, showed a decrease in the levels of sFlt-1 before and 48 hours after methyldopa therapy. Levels of sFlt-1 before methyldopa therapy in a dose of 250 mg was 10.15±10.00 (2.55-34.70) ng/ml and after therapy 8,37±9,20 (0.72-9.20) ng/ml, with a percentage decrease 17.54%. sFlt-1 levels before methyldopa therapy in a dose of 500 mg was 8.05±7.07 (2.55-20.76) ng/ml, after therapy 4.50±2.90 (2.19-9.95) ng/ml, with a percentage decrease 44.16%. Methyldopa therapy could decrease sFlt-1 levels of antiangiogenic factor in patients with severe preeclampsia.
Methotrexate use is safe in children with acute lymphoblastic leukemia Utomo, Febriansyah Nur; Yulistiani, Yulistiani; Zairina, Nun; Permono, Bambang
Folia Medica Indonesiana Vol. 53, No. 2
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Monitoring level of methotrexate is not only aimed at monitoring effectiveness, but also safety aspects of the administration of high-dose methotrexate because the use of high-dose methotrexate is one of the problems associated with toxicity in various organs. In the use of high-dose methotrexate, measurement of methotrexate is important to identify patients with a high risk of toxicity, particularly nephrotoxicity as well as for dosing guidelines for leucovorin therapy. The aim of this study was to analyze the safety of high-dose methotrexate on kidney function during chemotherapy consolidation phase in children with acute lymphoblastic leukemia. This was a longitudinal, observational prospective study conducted to determine the safety profile of high-dose methotrexate on kidney function during chemotherapy consolidation phase in children with acute lymphoblastic leukemia. Patients who met the inclusion criteria were given high-dose methotrexate according to the 2013 Indonesian ALL Chemotherapy Protocol. Measurement of methotrexate level and kidney function was done 3 times on each cycle of chemotherapy consolidation phase. Measurements were made on the 0, 24 and 48 hours after the first drop of high-dose methotrexate. This study had been reviewed by Ethics Committee of Dr. Soetomo Hospital Surabaya. There were 12 patients who met inclusion criteria and 6 patients among them had finished their chemotherapy consolidation phase completely. There was no significant change in kidney function after the administration of high-dose methotrexate compared to baseline (p>0.05) and there was no significant correlation between serum level of methotrexate versus creatinine clearance. In conclusion, methotrexate was safe to use in children with acute lymphoblastic leukemia.
Analysis of High Dose and Long-Term Prednisone Therapy on Trap 5B Level Change in Children with Steroid Sensitive Nephrotic Syndrome Setyani, Dessy Surya; Qibtiyah, Mariyatul; Asmaningsih, Ninik; Yulistiani, Yulistiani
Folia Medica Indonesiana Vol. 54, No. 2
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Nephrotic syndrome is a condition which is characterized by protein leakage from the blood to the urine through glomeruli. It leads to hypoproteinemia and generalised oedema. Patients with nephrotic syndrome need high dose and long term glucocorticoid such as prednisone. High dose and long term glucocorticoid can increase bone resorption. Biological marker is a valuable tool to evaluate efficacy of therapy. TRAP 5B is a sensitive biological marker for bone resorption because it reflects the number of osteoclasts. TRAP 5B is not affected by renal dysfunction and food. It also has a low diurnal variation than other bone resorption marker. The aim of this study was to analyze the changes of TRAP 5B levels at induction and alternate phase in children with steroid sensitive nephrotic syndrome. This observational prospective study was conducted from May to October 2016. Venous blood samples obtained at 08.00-10.00 am. TRAP5B levels were measured before and after induction phase and after alternate phase using ELISA. Fifteen patients were included in this study (60% boys). Majority of their age was 6 - <12 years and 40% were dependent steroid NS. TRAP 5B serum levels in induction phase increased by 37.41%±56.22%. In alternate phase, TRAP 5B serum levels increased by 28.75%±66.55% compared to the induction phase. However, the level change of both phases were not significant. As a conclusion, TRAP 5B levels increased in induction and alternate phase after high dose and long-term prednisone treatment in nephrotic syndrome.
Analysis of ANC Levels after Filgrastim Therapy in Acute Leukemia Children with Neutropenia Widya, Reta Anggraeni; Nugroho, Susanto; Winarsih, Sri; Yulistiani, Yulistiani
Folia Medica Indonesiana Vol. 55, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cytotoxic chemotherapy suppresses the hematopoietic system, and the most serious hematologic toxicity is neutropenia. This can decrease a risk of infection that causes delays in treatment and reduction of dose intensity, which reduces therapeutic outcome. Filgrastim is used to increase neutrophils level whose therapeutic effect is unknown. The effectiveness of filgrastim is based on the ANC level pre- and post-therapy. This study aimed to analyze the use of filgrastim on ANC level changes in acute leukemia children with neutropenia, and to analyze the patient that achieve ANC level's targeted therapy = 1000 cell/mm3. A prospective observational study with a longitudinal design was conducted from June to October 2016. The inclusion criteria of the study were patients who diagnosed acute leukemia with neutropenia and received filgrastim 10 µg/kgBW for 3, 4, 5 days. Patients' ANC levels were measured before and after filgrastim therapy. This study has been approved its ethical clearance by Dr. Saiful Anwar Hospital, Malang. Data were obtained on the basis of neutropenic episodes, followed by 7 episodes of obtaining filgrastim for 3 days, 1 episode of obtaining filgrastim for 4 days, and 7 episodes of obtaining filgrastim for 5 days. Thus, it consists of 15 episodes. In 3 days, ANC levels increased by 9.5 fold from 381.3 ± 91.8 cell/mm3 to 3984.9 ± 426.8 cell/mm3, but in 5 days, ANC levels decreased by 0.9 fold from 200.9 cell/mm3 ± 98.2 to 189.7 ± 14.2 cell/mm3. Filgrastim was able to increased the ANC levels around nine fold for 3 days of theraphy. There were 53% neutropenia patients who achieved the goal of therapy. Filgrastim therapy with dose 10 µg/kgBW for 3 to 5 days has been able to reach the therapeutic target of 53% in acute leukemia children with neutropenia. The increased levels of ANC maximum was reached on the third day with increased levels of 9.5 fold.
Review : Alirocumab dan Evolocumab sebagai Agen Penurun Lipid Baru Alfatihah, Humaira Izka; Yulistiani, Yulistiani
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.849

Abstract

Angka kematian yang disebabkan oleh penyakit kardiovaskular di seluruh dunia masih relatif tinggi. Salah satu faktor risikonya adalah LDL-C (low density lipoprotein cholesterol), di mana memodifikasi faktor ini diharapkan dapat mencegah kejadian kardiovaskular. Penghambat PCSK9 (proprotein convertase subtilisin/kexin type 9) adalah agen penurun lipid baru dengan mekanisme yang mempertahankan reseptor LDL-C di dalam darah. Untuk meninjau penelitian terbaru mengenai efektivitas dan keamanan agen penghambat PCSK9, Alirocumab dan Evolocumab, serta potensinya dalam menurunkan kadar lipid. Pencarian literatur menggunakan database elektronik PubMed dengan kata kunci ‘Alirocumab’, ‘Evolocumab’, ‘LDL-C’, ‘Kardiovaskular’, ‘Dislipidemia’, dengan kriteria 5 tahun terakhir dan teks lengkap dalam bahasa Inggris. Dari 12 artikel yang telah disaring kemudian akan direview. Nilai LDL-C menurun secara signifikan rata-rata 53% (11%-72%) dengan efek samping yang ringan, seperti nasofaringitis, diare, dan reaksi tempat suntikan. Alirocumab dan Evolocumab disuntikkan secara subkutan setiap 2 minggu atau 4 minggu. Penghambat PCSK9 berbasis antibodi monoklonal dapat menjadi alternatif untuk pencegahan kardiovaskular berisiko tinggi bagi pasien yang memiliki riwayat dosis statin yang dapat ditoleransi atau pasien yang tidak toleran terhadap statin.
Implementasi Program Skrining Kesehatan dan Edukasi Pola Hidup Sehat dalam Upaya Pencegahan Penyakit Tidak Menular Pratama, Muhammad Diva; Marpatmawati, Idhfi; Kusmiati, Meti; Anisa, Anisa; Fadhillah, Jenisa Nadhia; Aulia, Natasya Budi; Yuniartina, Gina; Yulistiani, Yulistiani; Ayuningsih, Nenden Maida; Robbany, Gianova Akhsan; Ningsih, Ernawati
BERDAYA: Jurnal Pendidikan dan Pengabdian Kepada Masyarakat Vol 8 No 2 (2026)
Publisher : LPMP Imperium

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36407/berdaya.v8i2.1816

Abstract

Non-Communicable Diseases (NCDs), including hypertension and diabetes mellitus (DM), are increasingly prevalent health concerns with the potential to cause serious complications, such as visual impairment. Insufficient public awareness regarding early detection of risk factors remains a primary contributor to delayed treatment. The Community Service Program was designed to enhance public knowledge and awareness through educational initiatives and early detection of NCD risk factors and eye health issues. The program was conducted using a participatory, in-person approach that incorporated health education and basic health screenings. The target population comprised residents of RT 03/RW 11 Kampung Sukasukur, with the involvement of local health cadres. Success indicators included community participation rates, the effective execution of screening activities, and the identification of health risk factors. The program achieved active community engagement. Health screenings identified a high prevalence of hypertension (70%), as well as several individuals with elevated uric acid and cholesterol levels. Additionally, two cases of cataracts and multiple instances of eye complaints, such as red eyes, were detected. The program positively influenced public understanding of healthy lifestyles and the importance of early disease detection, while also generating health data for use by health cadres in subsequent interventions.
Peran Caregiver terhadap Kualitas Hidup Pasien Lanjut Usia di Panti Sosial Tresna Werdha Budi Sejahtera I Yulistiani, Yulistiani
TRI DHARMA MANDIRI: Dissemination and Downstreaming of Research to the Community (Journal of Community Engagement) Vol 6 No 1 (2026)
Publisher : SMONAGENES Research Center, Univeritas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jtridharma.2026.006.01.22

Abstract

Pertambahan usia menyebabkan perubahan biologis dan psikososial yang dapat meningkatkan kerentanan lansia terhadap berbagai masalah kesehatan. Kondisi tersebut berpotensi memengaruhi kesejahteraan dan kualitas hidup mereka. Di Indonesia, proporsi penduduk lanjut usia terus menunjukkan tren peningkatan dan mencapai 11,75% pada tahun 2022. Berbagai faktor, baik fisik, emosional, maupun sosial, berkontribusi terhadap perubahan kualitas hidup pada kelompok usia ini. Penelitian ini bertujuan untuk mengevaluasi peran caregiver dalam meningkatkan kualitas hidup lansia di Panti Sosial Tresna Werdha Budi Sejahtera I, Kalimantan Selatan. Studi dilakukan menggunakan pendekatan observasional potong lintang terhadap 46 responden yang memenuhi kriteria penelitian. Pengukuran kualitas hidup dilakukan dengan instrumen WHOQOL-OLD. Hasil penelitian menunjukkan rata-rata skor kualitas hidup lansia sebesar 63,6% (kualitas hidup sedang), dengan domain aktivitas masa lalu, sekarang, masa depan serta domain persahabatan dan cinta kasih memperoleh skor tertinggi (67%), sementara domain kematian tercatat sebagai domain dengan skor terendah (50,7%). Temuan ini mengindikasikan bahwa dukungan sosial dan emosional yang diberikan caregiver berperan dalam mempertahankan kualitas hidup lansia di lingkungan panti. Oleh karena itu, penguatan program pendampingan berbasis caregiver menjadi strategi penting untuk menunjang kesejahteraan lansia di institusi sosial. KATA KUNCI: Kualitas hidup; Lanjut usia; Lansia; Pendamping
Drug Review : Oksitosin dan Misoprostol Pada Postpartum Hemorrhage (PPH) Aghnia Fuadatul Inayah; Yulistiani, Yulistiani; Ratnasari, Ayu; Tyas Angganawati, Rahmadhani; Sulistyono, Agus
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 9 No. 1 (2022)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v9i1.5350

Abstract

Postpartum Hemorrhage (PPH) merupakan penyebab yang sangat penting dari mortalitas dan morbiditas ibu di seluruh dunia. Seluruh pedoman merekomendasikan oksitosin intramuskular sebagai pengobatan uterotonik lini pertama untuk semua perempuan yang melahirkan pada persalinan trimester ketiga. Tujuan penelitian ini untuk membandingkan penggunaan oksitosin dan misoprostol berdasarkan dosis, dan aspek farmasi yang berupa bentuk sediaan, pemberian, stabilitas/penyimpanan dan efek samping umum yang terjadi pada pasien PPH. Studi ini merupakan narrative review yang dilakukan penelusuran pustaka melalui Google Scholar, Pubmed dan Science Direct. Dari hasil pencarian, diperoleh sebanyak 5855 jurnal dan terpilih 40 jurnal yang memenuhi kriteria inklusi. Kriteria inklusi yaitu memenuhi kaidah introduction, method results and discussion dan terbit selama 10 tahun terakhir. Jurnal yang tidak dapat diakses secara lengkap dieksklusi dan diperoleh sebanyak 23 jurnal. Hasil review menunjukkan profilaksis oksitosin mengurangi kehilangan darah dan kejadian PPH tanpa hasil yang merugikan. Penggunaan oksitosin dengan Uniject juga memberikan keuntungan pada penghematan biaya. Akan tetapi, penggunaan oksitosin harus diberikan oleh tenaga profesional. Dengan demikian, dapat disimpulkan pemberian oksitosin lebih diutamakan untuk PPH karena dari efek samping lebih minimal dibandingkan misoprostol.
Co-Authors A.A. Ketut Agung Cahyawan W Aghnia Fuadatul Inayah Agus Sulistyono Alfatihah, Humaira Izka Amarullah, Adinugraha Anggraini, Dian Septi Anisa Anisa Asmaningsih, Ninik Assaidiqi, M. Irfan Aulia, Natasya Budi AYU RATNASARI Ayuningsih, Nenden Maida Bagus PP Suryana, Bagus PP Bambang Permono Berliana, Dini Budi Suprapti Darto Saharso Desantika Wuryana, Desantika Didik Hasmono Dwiyatna, Surya Ekanita Desiani Erwin Saputra Siregar Fadhillah, Jenisa Nadhia Gustaji, F Herni Setyawati Herwati, Teri Wina Hidayatullah, Affan Yuniar Nur Julaeha, Julaeha Juwita, Dina Ratna Karisma, R F M, Eddy Zarkaty Mamo, Hendriette Irene Mariyatul Qibtiyah Markus, Unedo H Marpatmawati, Idhfi Melawati Olevianingrum, Melawati Mellyani, Netty Purnama Sari Meti Kusmiati, Meti Mia Ratwita Andarsini Muhammad Shohib, Muhammad Muhammad Yahya Muzayyanah, Binti Nazori, Nazori Nesimnasi, Reinaldo Erasmus Ningsih, Ernawati Nisriyati Fiddina Nun Zairina, Nun Nur ‘Azah Oktavia, Nur Permanasari, Ayu Ratna Pratama, Muhammad Diva Purwiningtyas, Mida Puspitasari, Hanni Prihhastuti Putra, Oki Nugraha Rahmadani, Rizal Umar Ramadhani, Sylvia Rizki Rana, Rana Rismayanti, Levana Robbany, Gianova Akhsan Rusmiyati, Melly Santi, Bayu Dharma Setyani, Dessy Surya Simbolon, Octaviana Soedarsono Soedarsono Sri Winarsih Styawati, Styawati Suharjono Susanto Nugroho Susilo, Dwi Hari Tyas Angganawati, Rahmadhani Ugrasena, I DG Ugrasena, IGD UMI FATMAWATI Utomo, Febriansyah Nur WAHYU WIBISONO Warni, Asri Indahning Widya, Reta Anggraeni Widya, Reta Anggraeni Wisudani, Nuraida Yuniartina, Gina