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All Journal E-Jurnal Medika Udayana BioWallacea Journal of Biological Research Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Gema Lingkungan Kesehatan Jurnal Abdi dan Dedikasi kepada Masyarakat Indonesia Jurnal Analis Kesehatan Kendari
Susanti Susanti
Politeknik Bina Husada Kendari
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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GAMBARAN GLUKOSA URINE DAN KETON URINE PASIEN HIPERTENSI DI RUMAH SAKIT UMUM DAERAH KOTA KENDARI Susanti Susanti; Ani Umar; Ephi Trianti
Jurnal Analis Kesehatan Kendari Vol. 4 No. 2 (2022): Jurnal Analis Kesehatan Kendari (JAKK : Vol. 4 (2) Juni 2022)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v4i2.184

Abstract

Hypertension is an increase in systolic blood pressure of at least 140 mmHg and a diastolic pressure of at least 90 mmHg. Urine is product of is end of system of metabolik released by kidney as remains or discard. Urine glucose is a simple sugar group that still in the urine after passing through various processes in the kidneys. Ketones is a metabolic product of fatty acids and proteins consisting of three compounds namely acetoacic acid, acetone, and beta hydroxybutyrate acid. Urine test can provide information about organabnormalities, but it can also be used to establish the result of treatment especially to monitor the development of disease such as high blood pressure (hypertension). Study aims to determine the description of glucose urine and ketone urine with patient hypertension. This type of research is descriptive by using device "study sectional cross" with sampling technique purposive sampling where the number of samples of 30 people. Based on the results of a study of 30 glucose urine and keton urine in patients hypertension at city general hospital kendari obtained normal urine glucose as many 5 patients (16,7%) and abnormal urine glucose 25 patients (83,3). While, ketone normal as many 30 patients (100%). Keywords : Hypertension, Glucose Urine, Keton Urine
UJI SKRINING ASTO (ANTI STREPTOLISIN O) PADA MANUSIA USIA LANJUT (MANULA) DI PANTI SOSIAL TRESNA WERDHA MINAULA RANOMEETO SULAWESI TENGGARA Susanti Susanti; Angriani Fusvita; Wa Fifi
Jurnal Analis Kesehatan Kendari Vol. 5 No. 1 (2022): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 5 (1) Desember 2022)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v5i1.218

Abstract

Elderly human is a process of growth that is carried out by every human being, which is characterized by a decrease in the body’s ability to adapt to the environment. Elderly human experience a decline in the immune system so that they are susceptible to various disease. Anti Streptolisin O (ASTO) are antibodies to the resulting streptolysin O antigen by bacterium Streptococcus B hemolyticus group A. Examination of Anti Streptolysin O (ASTO) is a blood test that works for to know the antibodies to streptolysin O produced by Streptolysin group A. The purpose of this study is to know the screening test of result anti streptolisin O (ASTO) in elderly human at the Tresna Werdha Minaula Ranomeeto social institution in Southeast Sulawesi,Elderly human samples were 30 samples with the taking technique sample is total sampling with latex test method. Based on the research that has been done can that from 30 samples there were 4 people (13%) positive samples Anti Streptolysin O (ASTO) is characterized by agglutination and 26 (87%) of the anticipated negative streptolysin O (ASTO) negative samples with no agglutination occuring. Key words: Anti Streptolysin O, Agglutination, Elderly Human, Social Institution
GAMBARAN KADAR SERUM GLUTAMIC OXALOACETIC TRANSAMINASE (SGOT) PADA PENDERITA HIV YANG MENGGUNAKAN OBAT ANTIRETROVIRALDI KOTA KENDARI Susanti Susanti; Muh Ilyas Yusuf; wahyu ningsih
Jurnal Analis Kesehatan Kendari Vol. 5 No. 2 (2023): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 5 (2) Juni 2023)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v5i2.252

Abstract

ABSTRACT HIV patients’ need treatment with Antiretroviral (ARV) to reduce the number of HIV viruses in the body so as not to enter the AIDS stage, whereas people with AIDS need ARV treatment to prevent opportunistic infections with their complications. ARV drugs can causes an increase in liver enzymes in HIV patients’ who cause liver damage related to antiretoviral drug-related liver injury (ARLI). HIV starts with an acute infection that cannot be overcome by an adaptive immune response and causes complications or disorders of various organs of the body, one of them is liver. One important complication of HIV infection after pneumia and sepsis. Damage to liver cells will be followed by the removal of enzymes including SGOT and SGPT. This study aims to determine the description of SGOT levels to HIV patients’ who used antiretroviral drugs. The type of this study used descriptive and the technique of sampling used Accidental Sampling with 20 samples. Based on the results of this study of 20 patients, showed that HIV patients’ who has abnormal SGOT levels as much as 7 people(35%) male and 2 people(10%) female. Keywords: Serum Glutamic OxaloaceticTransaminase (SGOT), Human Immunodeficiency Virus (HIV) ABSTRAK Penderita HIV memerlukan pengobatan dengan Antiretroviral (ARV) untuk menurunkan jumlah virus HIV didalam tubuh agar tidak masuk kedalam stadium AIDS, sedangkan pengidap AIDS memerlukan pengobatan ARV untuk mencegah terjadinya infeksi oportunistik dengan berbagai komplikasinya. Obat ARV dapat menyebabkan peningkatan enzim hati pada penderita HIV yang menyebabkan kerusakan hati terkait obat antiretroviral (antiretoviral drug-related liver injury/ ARLI).Penyakit HIV dimulai dengan infeksi akut yang tidak dapat diatasi oleh respon imun adiptif dan menyebabkan komplikas I atau gangguan pada berbagai organ tubuh salah satunya organ hati.Salah satu komplikasi penting dari infeksi HIV setelah pneumia dan sepsis. Kerusakan sel-sel hati akan diikuti oleh pengeluaran enzim-enzim antara lain SGOT dan SGPT. Penelitian ini bertujuan untuk mengetahui gambaran kadar SGOT pada penderita HIV yang menggunakan obat antiretroviral. Jenis penelitian ini adalah penelitian deskriptif dengan teknik pengambilan sampel secara Accidental Sampling dengan jumlah sampel sebanyak 20 sampel. Berdasarkan hasil penelitian terhadap 20 sampel menunjukan bahwa penderita HIV yang memiliki kadar SGOT tidak normal sebanyak 9 orang (45% ), 7 orang (35%) pada jenis kelamin laki-laki dan 2 orang (10%) pada perempuan. Kata Kunci: Serum Glutamic OxaloaceticTransaminase (SGOT), Human Immunodeficiency Virus (HIV)
PROFIL UREUM DAN KREATININ SERUM SEBAGAI INDIKATOR DISFUNGSI GINJAL PADA PENDERITA HIV YANG MENDAPAT TERAPI ANTIRETROVIRAL Susanti Susanti; Sri Aprilianti Idris; Firdayanti Firdayanti
Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Vol 9, No 2 (2025)
Publisher : STIKES Ar-Rum Salatiga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36409/jika.v9i2.263

Abstract

Human Immunodeviciency Virus (HIV) merupakan Retrovirus golongan RNA yang menyerang kekebalan tubuh manusia. Penderita HIV harus memakai obat ARV seumur hidup yang untuk mencegah replikasi virus HIV di dalam tubuh. Efek samping dari penggunaan obat Antiretroviral terjadi toksisitas yang akan menyebabkan terganggunya fungsi ginjal yang ditandai oleh suatu kondisi yang memicu infeksi neoplasma sekunder, dan manifestasi neurologis dari kadar ureum. Penelitian ini dilaksanakan di Laboratorium Kimia Klinik Analis Kesehatan Politeknik Bina Husada Kendari pada bulan April 2019. Tujuan dari penelitian ini adalah untuk mengetahui profil ureum dan kreatinin serum sebagai indikator disfungsi ginjal pada penderita HIV yang mendapat terapi antiretroviral. Jenis Penelitian yang digunakan adalah deskriptif analitik dengan metode pengambilan sampel cross sectional study untuk melakukan pemeriksaan kadar ureum dan kreatinin pada 20 sampel darah penderita HIV/AIDS dengan menggunakan tekhnik pengambilan sampel total sampling serta dianalisis secara statistik menggunakan uji regresi linear sederhana. Hasil penelitian menunjukkan hasil analisis secara statistik menggunakan regresi linear sederhana menunjukkan bahwa nilai yang signifikan p=0,684 (p>0,05) artinya tidak terdapat hubungan antara lama penggunaan obat ART dengan kadar ureum dan kreatinin pada penderita HIV.
Korelasi Indeks Eritrosit Dan Red Cell Distribution Width (RDW) Pada Pasien Gagal Ginjal Kronik di Instalasi Hemodialisa RSUD Bahteramas Bonni Rubak; Susanti; Reymon; Sendy Ramadhany
Jurnal Analis Kesehatan Kendari Vol. 7 No. 2 (2025): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 7 (2) Juni 2025)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v7i2.349

Abstract

Chronic kidney failure (CKD) is a disease condition that progressively occurs with a slow decline in kidney function that cannot return to normal, so that in advanced stages it requires replacement therapy such as hemodialysis. One of the most common complications in patients with CKD is anemia. This anemia is usually caused by reduced production of erythropoietin hormone which causes a shortening of erythrocyte lifespan. To evaluate the characteristics of anemia in chronic kidney failure (CKD) patients, hematological examination of erythrocyte indices, including Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), and Mean Corpuscular Hemoglobin Concentration (MCHC), as well as Red Cell Distribution Width (RDW), are performed. This study aims to determine the correlation between erythrocyte indices (MCV, MCH, and MCHC) and Red Cell Distribution Width (RDW) in CKD patients undergoing hemodialysis at Bahteramas Hospital. The study was conducted descriptively analytically with accidental sampling method of 77 CKD patients. The results of statistical analysis using the chi-square test showed a significant value in the MCV examination and RDW value of 0.000 under the p value <0.05, MCH examination and RDW value found a significant value of 0.000 under the p value <0.05, and MCHC examination and RDW value found a significant value of 0.000 under the p value <0.05. This shows that there is a statistically significant relationship between erythrocyte index and RDW value in CKD patients in the Hemodialysis Installation at Bahteramas Hospital.
Education on the Dangers of Environmental Chemical Exposure and Urine Protein Examination as Risk Factors for Impaired Renal Function Among Students at SDN 6 Kendari Yanti, Firda; Umar, Ani; Jung, Jeoun; Tantrakarnapa, Kraichat; Idris, Sri Aprilianti; Susanti, Susanti; Setiawan, Muhammad Azdar; Aulya, Muhammad Sultanul; Balaka, Kemal Idris; Tosepu, Ramadhan; Dharmawati, Tuti; Fusvita, Angriani; Yodha, Agung Wibawa Mahatva
Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Community Engagement) Vol 12, No 1 (2026): Maret
Publisher : Direktorat Pengabdian kepada Masyarakat Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpkm.103358

Abstract

This community service activity aimed to improve primary school students’ knowledge regarding environmental chemical exposure and kidney health while introducing a simple renal screening approach as an educational awareness tool. The program was conducted in 2023 at Sekolah Dasar Negeri 6 Kendari and involved 30 grade 5 and grade 6 students selected using accidental sampling. The activities consisted of interactive, age-appropriate education sessions and preliminary screening using urine protein dipstick testing, together with serum urea and creatinine measurements. Knowledge scores increased from a mean of 3.13 (SD 1.93) before the education sessions to 8.83 (SD 1.02) after the sessions (p < 0.001), indicating substantial short-term improvement in understanding. Most participants had negative urine protein findings, with a small proportion showing low-level positivity, whereas biochemical values were generally within expected ranges. The screening results are presented descriptively to support awareness and should not be interpreted as a clinical diagnosis or as evidence of impaired renal function. Overall, the activity demonstrates the feasibility of integrating school-based health education with simple screening to promote awareness and engagement, providing a practical model for community health promotion while avoiding overstatement of clinical implications.
Platelet to cholesterol ratio of high density lipoprotein cholesterol is associated with diabetes and comorbidity risk Ani Umar; Firdayanti; Heni Umar; Angriani Fusvita; Susanti; Sri Aprilianti Idris
Gema Lingkungan Kesehatan Vol. 24 No. 2 (2026): Gema Lingkungan Kesehatan (on progress)
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v24i2.452

Abstract

This study aims to analyze the relationship between platelet to HDL cholesterol (Platelet to HDL Ratio / PHR) ratio and the presence of type 2 diabetes mellitus, as well as evaluate the ability of PHR as a predictor of comorbidity risk. Multivariate logistic regression analysis was used to estimate the odds ratio (OR) and 95% CI. The discriminatory ability of the model is evaluated with the receiver operating characteristic curve (ROC), with the area under the curve (AUC) used to measure the model's performance. Sensitivity and specificity. This study used a cross-sectional observational design with 220 participants (110 type 2 diabetes patients and 110 non-diabetic controls) from the Southeast Sulawesi Provincial General Hospital. Samples were selected based on inclusion criteria (age 30–70 years, for the diabetes group) and exclusion (such as anemia or use of anticoagulant drugs). Data were collected through clinical examinations (age, BMI, blood pressure, platelet count, HDL). PHR is calculated as the number of platelets (per μL) divided by HDL levels (mg/dL). Statistical analysis was performed using independent t-test, multivariate logistic regression, and ROC curve with SPSS software (p < 0.05). The results showed that PHR was significantly higher in the diabetes group with comorbidities (mean 5.49±2.10) than in healthy individuals (4.25±2.39; p < 0.001). The ROC curve shows an AUC of 0.70 for PHR in predicting comorbidity risk, better than HDL alone (AUC 0.55). This study shows that platelet-to-HDL ratio (PHR) is proven to be a simple and economical potential biomarker for detecting an association with diabetes and predicting the risk of vascular comorbidities. These findings support the use of PHR in routine clinical practice, especially in developing countries such as Indonesia. This research contributes to the strategy for the early prevention of diabetes complications through easily accessible hematological parameters.
Co-Authors Alma Dita Harun Angriani Fusvita Ani Umar Aulya, Muhammad Sultanul Balaka, Kemal Idris Bobi Anggriawan Bonni Rubak Dharmawati, Tuti Ephi Trianti Firda yanti, Firda Firdayanti Firdayanti Firdayanti Fitrayana Sari Fusvita, Angriani Heni Umar Idris, Sri Aprilianti irin aprilin janhar Jung, Jeoun Muh Ilyas Yusuf Muh. Azdar Setiawan Muhammad Ilyas Y Nizma Rahmawati Nurul Afdhaliyah Nurdin Ramadhan Tosepu Reymon Sendy Ramadhany Sernita Sernita Sernita Sernita Setiawan, Muhammad Azdar Sri Aprilianti Idris Sri Aprilianti Idris Sri Aprilianti Idris Suci Devianti Ningsih Tantrakarnapa, Kraichat Umar, Ani Wa Fifi wahyu ningsih Yodha, Agung Wibawa Mahatva