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Susanti Susanti
Politeknik Bina Husada Kendari
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GAMBARAN KADAR SERUM GLUTAMIC OXALOACETIC TRANSAMINASE (SGOT) PADA PASIEN JANTUNG KORONER Susanti Susanti; Angriani Fusvita; Ani Umar
Jurnal Analis Kesehatan Kendari Vol. 3 No. 2 (2021): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 3 (2) Juni 2021)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v3i2.110

Abstract

ABSTRACT Coronary heart disease is a narrowing of the internal coronary arteries caused by lesions and atherosclerosis and causes damage to blood vessel walls. Coronary heart patients can be ascertained that there is an increase in SGOT levels in the patient's blood. This is because SGOT can increase levels of myocardial infarction. Myocardial infarction is a blockage of blood flow to the heart muscle. This study aims to describe the level of SGOT in coronary heart patients in the Regional General Hospital of Kendari City. This type of research is descriptive with accidental sampling technique with a total sample of 10 people. The examination was carried out using the enzymatic kinetic method. The results of the study were 10 patients with Glutamic Oxaloacetic Transaminase (SGOT) (SGOT) in coronary heart patients, 3 patients with increased levels and 7 patients with normal results. Keywords: Coronary Heart Disease, SGOT ABSTRAK Penyakit jantung koroner adalah penyempitan arteri koroner internal yang disebabkan oleh adanya lesi dan arterosklerosis serta mengakibatkan kerusakan dinding pembuluh darah. Pasien jantung koroner bisa dipastikan terjadi peningkatan kadar SGOT pada darah penderita. Hal ini disebabkan karena SGOT dapat meningkat kadarnya pada infark miokard. Infark miokard merupakan suatu penyumbatan aliran darah ke otot jantung. Penelitian ini bertujuan untuk mengetahui gambaran kadar SGOT pada pasien jantung koroner di Rumah Sakit Umum Daerah Kota Kendari. Jenis penelitian ini adalah deskriptif dengan teknik pengambilan sampel accidental sampling dengan jumlah sampel sebanyak 10 orang. Pemeriksaan dilakukan menggunakan metode kinetik enzimatik.Hasil penelitian kadar Serum Glutamic Oxaloacetic Transaminase (SGOT) pada pasien jantung koroner sebanyak 10 pasien, ditemukan 3 pasien yang kadarnya meningkat dan 7 pasien yang hasilnya normal. Kata Kunci : Penyakit Jantung Koroner, SGOT, Kendari
GAMBARAN RED BLOOD CELL DISTRIBUTION WIDTH (RDW) PADA IBU HAMIL TRIMESTER II DI PUSKESMAS POASIA Sri Aprilianti Idris; Susanti Susanti; Fitrayana Sari
Jurnal Analis Kesehatan Kendari Vol. 3 No. 2 (2021): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 3 (2) Juni 2021)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v3i2.113

Abstract

ABSTRACT Trimester II pregnant women is a pregnant woman with 15 weeks of gestation (week 13 to 27). Trimester II pregnant women often have iron deficiency anemia can affect the examination value of Red Blood Cell Distribution Width (RDW). Red Blood Cell Distribution Width (RDW) is the difference in size or extent of red blood cells. RDW changes are influenced by many factors such as anemia, renal dysfunction or liver dysfunction, hepatic dysfunction, thyroid disease, acute transfusion or chronic inflammation, neurohormonal activation, malnutrition (iron, vitamin B12 and folic acid), ethnicity, bone marrow suppression, and use of some medicines. This study aims to find out the description of Red Blood Cell Distribution Width (RDW) in Trimester II pregnant women at Puskesmas Poasia of Kendari City used analyzer hematology method. The type of this research is descriptive with sampling technique is accidental sampling technique, with the number of samples as much as 15 people. The results of a study of 15 patients of trimester II pregnant women at the Poasia Public Health Center in Kendari City, a normal RDW-SD score of 10 (66.7%) and a high of 5 (33.3%), a normal RDW-CV was 10 ( 66.7%) people and a high of 5 people (33.3%). Keywords : Trimester II pregnant women, Red Blood Cell Distribution Width ABSTRAK Ibu hamil trimester II adalah ibu hamil dengan usia kehamilan 15 minggu (minggu ke-13 hingga ke-27). Ibu hamil trimester II sering kali mengalami anemia defisiensi zat besi yang dapat mempengaruhi nilai pemeriksaan Red Blood Cell Distribution Width (RDW). Red Blood Cell Distribution Width (RDW) adalah perbedaan ukuran atau luas dari sel darah merah. Perubahan RDW dipengaruhi oleh banyak faktor seperti anemia, disfungsi ginjal atau disfungsi hati, penyakit tiroid, tranfusi, akut atau peradangan kronis, aktivasi neurohormonal, malnutrisi (zat besi, vitamin B12 dan asam folat), etnis, tulang depresi sumsum, dan penggunaan beberapa obat. Penelitian ini bertujuan untuk mengetahui Gambaran Red Blood Cell Distribution Width (RDW) pada Ibu Hamil Trimester II di Puskesmas Poasia Kota Kendari, menggunakan metode hematologi analyzer. Jenis penelitian ini adalah deskriptif dengan teknik pengambilan sampel accidental sampling, dengan jumlah sampel sebanyak 15 orang. Hasil penelitian terhadap 15 pasien ibu hamil trimester II di Puskesmas Poasia Kota Kendari diperoleh nilai RDW-SD normal sebanyak 10 (66,7%) orang dan yang tinggi sebanyak 5 orang (33,3%), RDW-CV normal sebanyak 10 (66,7%) orang dan yang tinggi sebanyak 5 orang (33,3%) . Kata Kunci : Ibu Hamil Trimester II, Red Blood Cell Distribution Width
GAMBARAN KETON URINE PADA PASIEN TUBERKULOSIS PARU YANG MENGKONSUMSI OBAT ANTI TUBERKULOSIS (OAT) DI PUSKESMAS LEPOLEPO KOTA KENDARI Susanti susanti; Sernita Sernita
Jurnal Analis Kesehatan Kendari Vol. 4 No. 1 (2021): Jurnal Analis Kesehatan Kendari (JAKK : Vol. 4 (1) Desember 2021)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v4i1.170

Abstract

ABSTRAK Tuberkulosis merupakan infeksi kronis yang disebabkan oleh bakteri Mycobacterim Tuberculosis. Pasien dengan tuberkulosis dapat mengalami penurunan nafsu makan juga muntah oleh karena efek samping obat. Hal ini dapat menyebabkan terbentuknya keton dalam tubuh oleh karena pasokan glukosa yang kurang. Keton dapat digunakan sebagai energi pengganti yang didapat dari metabolisme lemak. Jumlahnya yang berlebih juga akan keluar didalam urin (ketonuria) dan keberadaanya dalam urin bukanlah keadaan yang normal. Tujuan penelitian ini untukmengetahui gambaran keton urin pada pasien tuberkulosis penggun aobat anti tuberkulosis (OAT) di Puskesmas Lepo-Lepo Kota Kendari. Jenis penelitian ini adalah deskriptif dan pengambilan sampel dengan accidental sampling dari bulan Mare-April 2019. Sampel penelitian ini adalah urin sewaktu dan menggunakan metode carik celup pada 30 pasien tuberkulosis yang mengonsumsi obat anti tuberkulosis (OAT). Berdasarkan hasil pemeriksaan dari 30 sampel menunjukan bahwa semua sampel negatif ketonuria. Kata kunci: tuberculosis paru, urinalisis, keton. ABSTRACT Tuberculosis is a chronic infection caused by the bacterium Mycobacterim Tuberculosis. Patients with tuberculosis can experience decreased appetite as well as vomiting due to drug side effects. This can cause the formation of ketone bodies in the body due to lack of glucose supply. Ketones can be used as replacement energy derived from fat metabolism. The excess amount will also come out in the urine (ketonuria) and its presence in the urine is not a normal condition. The purpose of this study was to determine the description of urinary ketones in tuberculosis patients using anti-tuberculosis drugs (OAT) in the Lepo-Lepo Health Center in Kendari City. The type of research is descriptive and sampling with accidental sampling from April to May 2019. The study sample was urine when in 30 tuberculosis patients taking anti-tuberculosis (OAT) drugs. Based on the results of examinations from 30 samples showing that all ketonuria negative samples.Keywords: pulmonary tuberculosis, urinalysis, ketones.
GAMBARAN GLUKOSA URINE DAN KETON URINE PASIEN HIPERTENSI DI RUMAH SAKIT UMUM DAERAH KOTA KENDARI Susanti Susanti; Ani Umar; Ephi Trianti
Jurnal Analis Kesehatan Kendari Vol. 4 No. 2 (2022): Jurnal Analis Kesehatan Kendari (JAKK : Vol. 4 (2) Juni 2022)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v4i2.184

Abstract

Hypertension is an increase in systolic blood pressure of at least 140 mmHg and a diastolic pressure of at least 90 mmHg. Urine is product of is end of system of metabolik released by kidney as remains or discard. Urine glucose is a simple sugar group that still in the urine after passing through various processes in the kidneys. Ketones is a metabolic product of fatty acids and proteins consisting of three compounds namely acetoacic acid, acetone, and beta hydroxybutyrate acid. Urine test can provide information about organabnormalities, but it can also be used to establish the result of treatment especially to monitor the development of disease such as high blood pressure (hypertension). Study aims to determine the description of glucose urine and ketone urine with patient hypertension. This type of research is descriptive by using device "study sectional cross" with sampling technique purposive sampling where the number of samples of 30 people. Based on the results of a study of 30 glucose urine and keton urine in patients hypertension at city general hospital kendari obtained normal urine glucose as many 5 patients (16,7%) and abnormal urine glucose 25 patients (83,3). While, ketone normal as many 30 patients (100%). Keywords : Hypertension, Glucose Urine, Keton Urine
UJI SKRINING ASTO (ANTI STREPTOLISIN O) PADA MANUSIA USIA LANJUT (MANULA) DI PANTI SOSIAL TRESNA WERDHA MINAULA RANOMEETO SULAWESI TENGGARA Susanti Susanti; Angriani Fusvita; Wa Fifi
Jurnal Analis Kesehatan Kendari Vol. 5 No. 1 (2022): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 5 (1) Desember 2022)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v5i1.218

Abstract

Elderly human is a process of growth that is carried out by every human being, which is characterized by a decrease in the body’s ability to adapt to the environment. Elderly human experience a decline in the immune system so that they are susceptible to various disease. Anti Streptolisin O (ASTO) are antibodies to the resulting streptolysin O antigen by bacterium Streptococcus B hemolyticus group A. Examination of Anti Streptolysin O (ASTO) is a blood test that works for to know the antibodies to streptolysin O produced by Streptolysin group A. The purpose of this study is to know the screening test of result anti streptolisin O (ASTO) in elderly human at the Tresna Werdha Minaula Ranomeeto social institution in Southeast Sulawesi,Elderly human samples were 30 samples with the taking technique sample is total sampling with latex test method. Based on the research that has been done can that from 30 samples there were 4 people (13%) positive samples Anti Streptolysin O (ASTO) is characterized by agglutination and 26 (87%) of the anticipated negative streptolysin O (ASTO) negative samples with no agglutination occuring. Key words: Anti Streptolysin O, Agglutination, Elderly Human, Social Institution
GAMBARAN KADAR SERUM GLUTAMIC OXALOACETIC TRANSAMINASE (SGOT) PADA PENDERITA HIV YANG MENGGUNAKAN OBAT ANTIRETROVIRALDI KOTA KENDARI Susanti Susanti; Muh Ilyas Yusuf; wahyu ningsih
Jurnal Analis Kesehatan Kendari Vol. 5 No. 2 (2023): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 5 (2) Juni 2023)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v5i2.252

Abstract

ABSTRACT HIV patients’ need treatment with Antiretroviral (ARV) to reduce the number of HIV viruses in the body so as not to enter the AIDS stage, whereas people with AIDS need ARV treatment to prevent opportunistic infections with their complications. ARV drugs can causes an increase in liver enzymes in HIV patients’ who cause liver damage related to antiretoviral drug-related liver injury (ARLI). HIV starts with an acute infection that cannot be overcome by an adaptive immune response and causes complications or disorders of various organs of the body, one of them is liver. One important complication of HIV infection after pneumia and sepsis. Damage to liver cells will be followed by the removal of enzymes including SGOT and SGPT. This study aims to determine the description of SGOT levels to HIV patients’ who used antiretroviral drugs. The type of this study used descriptive and the technique of sampling used Accidental Sampling with 20 samples. Based on the results of this study of 20 patients, showed that HIV patients’ who has abnormal SGOT levels as much as 7 people(35%) male and 2 people(10%) female. Keywords: Serum Glutamic OxaloaceticTransaminase (SGOT), Human Immunodeficiency Virus (HIV) ABSTRAK Penderita HIV memerlukan pengobatan dengan Antiretroviral (ARV) untuk menurunkan jumlah virus HIV didalam tubuh agar tidak masuk kedalam stadium AIDS, sedangkan pengidap AIDS memerlukan pengobatan ARV untuk mencegah terjadinya infeksi oportunistik dengan berbagai komplikasinya. Obat ARV dapat menyebabkan peningkatan enzim hati pada penderita HIV yang menyebabkan kerusakan hati terkait obat antiretroviral (antiretoviral drug-related liver injury/ ARLI).Penyakit HIV dimulai dengan infeksi akut yang tidak dapat diatasi oleh respon imun adiptif dan menyebabkan komplikas I atau gangguan pada berbagai organ tubuh salah satunya organ hati.Salah satu komplikasi penting dari infeksi HIV setelah pneumia dan sepsis. Kerusakan sel-sel hati akan diikuti oleh pengeluaran enzim-enzim antara lain SGOT dan SGPT. Penelitian ini bertujuan untuk mengetahui gambaran kadar SGOT pada penderita HIV yang menggunakan obat antiretroviral. Jenis penelitian ini adalah penelitian deskriptif dengan teknik pengambilan sampel secara Accidental Sampling dengan jumlah sampel sebanyak 20 sampel. Berdasarkan hasil penelitian terhadap 20 sampel menunjukan bahwa penderita HIV yang memiliki kadar SGOT tidak normal sebanyak 9 orang (45% ), 7 orang (35%) pada jenis kelamin laki-laki dan 2 orang (10%) pada perempuan. Kata Kunci: Serum Glutamic OxaloaceticTransaminase (SGOT), Human Immunodeficiency Virus (HIV)
PROFIL UREUM DAN KREATININ SERUM SEBAGAI INDIKATOR DISFUNGSI GINJAL PADA PENDERITA HIV YANG MENDAPAT TERAPI ANTIRETROVIRAL Susanti Susanti; Sri Aprilianti Idris; Firdayanti Firdayanti
Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Vol 9, No 2 (2025)
Publisher : STIKES Ar-Rum Salatiga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36409/jika.v9i2.263

Abstract

Human Immunodeviciency Virus (HIV) merupakan Retrovirus golongan RNA yang menyerang kekebalan tubuh manusia. Penderita HIV harus memakai obat ARV seumur hidup yang untuk mencegah replikasi virus HIV di dalam tubuh. Efek samping dari penggunaan obat Antiretroviral terjadi toksisitas yang akan menyebabkan terganggunya fungsi ginjal yang ditandai oleh suatu kondisi yang memicu infeksi neoplasma sekunder, dan manifestasi neurologis dari kadar ureum. Penelitian ini dilaksanakan di Laboratorium Kimia Klinik Analis Kesehatan Politeknik Bina Husada Kendari pada bulan April 2019. Tujuan dari penelitian ini adalah untuk mengetahui profil ureum dan kreatinin serum sebagai indikator disfungsi ginjal pada penderita HIV yang mendapat terapi antiretroviral. Jenis Penelitian yang digunakan adalah deskriptif analitik dengan metode pengambilan sampel cross sectional study untuk melakukan pemeriksaan kadar ureum dan kreatinin pada 20 sampel darah penderita HIV/AIDS dengan menggunakan tekhnik pengambilan sampel total sampling serta dianalisis secara statistik menggunakan uji regresi linear sederhana. Hasil penelitian menunjukkan hasil analisis secara statistik menggunakan regresi linear sederhana menunjukkan bahwa nilai yang signifikan p=0,684 (p>0,05) artinya tidak terdapat hubungan antara lama penggunaan obat ART dengan kadar ureum dan kreatinin pada penderita HIV.
Korelasi Indeks Eritrosit Dan Red Cell Distribution Width (RDW) Pada Pasien Gagal Ginjal Kronik di Instalasi Hemodialisa RSUD Bahteramas Bonni Rubak; Susanti; Reymon; Sendy Ramadhany
Jurnal Analis Kesehatan Kendari Vol. 7 No. 2 (2025): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 7 (2) Juni 2025)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v7i2.349

Abstract

Chronic kidney failure (CKD) is a disease condition that progressively occurs with a slow decline in kidney function that cannot return to normal, so that in advanced stages it requires replacement therapy such as hemodialysis. One of the most common complications in patients with CKD is anemia. This anemia is usually caused by reduced production of erythropoietin hormone which causes a shortening of erythrocyte lifespan. To evaluate the characteristics of anemia in chronic kidney failure (CKD) patients, hematological examination of erythrocyte indices, including Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), and Mean Corpuscular Hemoglobin Concentration (MCHC), as well as Red Cell Distribution Width (RDW), are performed. This study aims to determine the correlation between erythrocyte indices (MCV, MCH, and MCHC) and Red Cell Distribution Width (RDW) in CKD patients undergoing hemodialysis at Bahteramas Hospital. The study was conducted descriptively analytically with accidental sampling method of 77 CKD patients. The results of statistical analysis using the chi-square test showed a significant value in the MCV examination and RDW value of 0.000 under the p value <0.05, MCH examination and RDW value found a significant value of 0.000 under the p value <0.05, and MCHC examination and RDW value found a significant value of 0.000 under the p value <0.05. This shows that there is a statistically significant relationship between erythrocyte index and RDW value in CKD patients in the Hemodialysis Installation at Bahteramas Hospital.
Platelet to cholesterol ratio of high density lipoprotein cholesterol is associated with diabetes and comorbidity risk Ani Umar; Firdayanti; Heni Umar; Angriani Fusvita; Susanti; Sri Aprilianti Idris
Gema Lingkungan Kesehatan Vol. 24 No. 2 (2026): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v24i2.452

Abstract

This study aims to analyze the relationship between platelet to HDL cholesterol (Platelet to HDL Ratio / PHR) ratio and the presence of type 2 diabetes mellitus, as well as evaluate the ability of PHR as a predictor of comorbidity risk. Multivariate logistic regression analysis was used to estimate the odds ratio (OR) and 95% CI. The discriminatory ability of the model is evaluated with the receiver operating characteristic curve (ROC), with the area under the curve (AUC) used to measure the model's performance. Sensitivity and specificity. This study used a cross-sectional observational design with 220 participants (110 type 2 diabetes patients and 110 non-diabetic controls) from the Southeast Sulawesi Provincial General Hospital. Samples were selected based on inclusion criteria (age 30–70 years, for the diabetes group) and exclusion (such as anemia or use of anticoagulant drugs). Data were collected through clinical examinations (age, BMI, blood pressure, platelet count, HDL). PHR is calculated as the number of platelets (per μL) divided by HDL levels (mg/dL). Statistical analysis was performed using independent t-test, multivariate logistic regression, and ROC curve with SPSS software (p < 0.05). The results showed that PHR was significantly higher in the diabetes group with comorbidities (mean 5.49±2.10) than in healthy individuals (4.25±2.39; p < 0.001). The ROC curve shows an AUC of 0.70 for PHR in predicting comorbidity risk, better than HDL alone (AUC 0.55). This study shows that platelet-to-HDL ratio (PHR) is proven to be a simple and economical potential biomarker for detecting an association with diabetes and predicting the risk of vascular comorbidities. These findings support the use of PHR in routine clinical practice, especially in developing countries such as Indonesia. This research contributes to the strategy for the early prevention of diabetes complications through easily accessible hematological parameters.
The Correlation Results of Examination of Hemoglobin and The Erythrocyte Index in Patients With Suspected Covid-19 in The Hospital of Kendari City Sri Aprilianti Idris; Firdayanti Firdayanti; Susanti Susanti; Muh. Azdar Setiawan
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 4 No 1 (2022): The future of diagnostic laboratory testing
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v4i1.2105

Abstract

Coronavirus disease 2019 has become a global problem causing hundreds of thousands of deaths worldwide. Haemoglobin is more susceptible to COVID-19 virus attacks. Haemoglobin functions as a carrier of oxygen to organs in the body. When the concentration of haemoglobin in the blood circulation is low, the transport of oxygen to several organs in the body can be disrupted. SARS-CoV-2 interacts with haemoglobin in red blood cells. This interaction causes the virus to break the haemoglobin chain and cause hemolysis. The erythrocyte index which consists of MCV, MCH, and MCHC values ​​is used to indicate the occurrence of anemia in COVID-19 patients. This research method used descriptive analytic with a cross sectional study design. The population of this study was suspected COVID-19 patients with a sample of 27 people. Sampling was carried out using purposive sampling. This study aims to determine the relationship between haemoglobin examination results and erythrocyte index in suspected COVID-19 patients.The instrument in this study used secondary data which included the results of examination of haemoglobin values ​​and erythrocyte index. The results of the test using a parametric statistical approach with the correlation analysis method showed that there was a correlation between the results of the haemoglobin and MCV test (P-value 0.057 > 0.05), while the haemoglobin and MCH test had no correlation (P value 0.777 > 0.05), and there is no correlation between haemoglobin and MCHC examination (P-value 0.372 > 0.05).
Co-Authors Agung Wibawa Mahatva Yodha Alma Dita Harun Angriani Fusvita Angriani Fusvita Ani Umar Balaka, Kemal Idris Bobi Anggriawan Bonni Rubak Ephi Trianti Firda Yanti Firdayanti Firdayanti Firdayanti Firdayanti Fitrayana Sari Heni Umar irin aprilin janhar Jeoun Jung Kemal Idris Balaka Kraichat Tantrakarnapa Muh Ilyas Yusuf Muhammad Ilyas Y Muhammad Sultanul Aulya Nizma Rahmawati Nurmina Nurmina Nurul Afdhaliyah Nurdin Ramadhan Tosepu Reymon, Reymon Sendy Ramadhany Sernita Setiawan, Muhammad Azdar Sri Aprilianti Idris Suci Devianti Ningsih Tuti Dharmawati Wa Fifi wahyu ningsih