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All Journal Jurnal Kesehatan Andalas Gelar : Jurnal Seni Budaya Majalah Kedokteran Andalas Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Penyakit Dalam Indonesia Journal of Educational Research and Humaniora (JERH) Jurnal Sains, Teknologi dan Kesehatan
Efrida Efrida, Efrida
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Arts Humanities Computer Science & IT Education Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Karakteristik Pasien Leukemia Granulositik Kronik Berdasarkan Hasil Direct Coomb’s Test di RSUP Dr. M. Djamil Zahira, Aisyah Dhia; Rofinda, Zelly Dia; Izzah, Amirah Zatil; Efrida, Efrida; Afriant, Rudy; Rahmatini, Rahmatini
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 3 (2024): September 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i3.1314

Abstract

Abstrak Latar Belakang: Leukemia Granulositik Kronik (LGK) merupakan penyakit mieloproliferatif yang ditandai dengan adanya proliferasi seri granulosit tanpa ada gangguan diferensiasi. Direct Coomb’s Test (DCT) digunakan untuk mendekteksi adanya antibodi imun, baik IgG maupun komponen komplemen (umumnya C3d) yang menutupi atau mensensitisasi sel eritrosit. Pemeriksaan coomb’s test pada pasien LGK dilakukan apabila adanya kecurigaan anemia dan terjadinya retikulositosis tanpa ditemukan adanya sumber perdarahan yang jelas. Objektif: Tujuan penelitian ini untuk mengetahui karakteristik pasien LGK berdasarkan hasil direct coomb’s test di RSUP Dr. M.Djamil Padang. Metode: Penelitian deskriptif dilakukan terhadap semua pasien yang didiagnosis LGK yang memiliki hasil direct coomb’s test. Pengambilan sampel dilakukan secara consecutive sampling dengan 30 sampel yang memiliki data berupa usia, jenis kelamin, hasil direct coomb’s test, derajat anemia, hitung retikulosit, dan jenis terapi. Hasil: Penelitian berdasarkan jenis kelamin pada pasien leukemia granulositik kronik didapatkan lebih banyak perempuan yaitu 18 pasien (60%) dan laki-laki 12 pasien (40%) dengan rerata usia 44 tahun. Direct coomb’s test menunjukkan hasil positif pada 21 pasien (70%) dan negatif pada 9 pasien (30%). Anemia berat paling banyak ditemukan pada direct coomb’s test negatif dengan 55,6%. Retikulositosis lebih banyak ditemukan pada hasil direct coomb’s test positif. Kesimpulan: Pasien LGK dengan hasil direct coomb’s test positif lebih banyak ditemukan anemia berat, anemia sedang, dan retikulositosis. Kata kunci: direct coomb’s test, leukemia granulositik kronik, luka sedang
PERBEDAAN HASIL PEMERIKSAAN HEMATOLOGI BERDASARKAN DERAJAT KEPARAHAN PASIEN COVID-19 DI RUMAH SAKIT SEMEN PADANG TAHUN 2021 Puja, Annisa Fitria; Efrida, Efrida; Permana, Hendra; Yulia, Dwi; Welan, Rahmani
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 2 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Juni 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i2.1308

Abstract

Objective: To determine differences in the results of hematological examinations based on the severity of COVID-19 patients at Semen Padang Hospital in 2021. Methods: The type of research was observational analytic with a cross-sectional design. We took secondary data from the medical records of COVID-19 patients. A total of 100 patients were included in this study was conducted at Semen Padang Hospital in January-December 2021. Bivariate analysis used a one-way ANOVA with the Kruskal-Wallis alternative. The results are considered as significant if p <0.05. The significance of the parameters was tested using the Post Hoc Scheffe (p<0.05). Results: From 100 patients found the: 60% Male and 40% female, mean age of 51.95 ± 12.82 years, mild COVID-19 patients 36%, moderate 44%, severe 14%, and critical 6%. The mean hematological parameters were within normal limits. Hemoglobin levels (g/dL) of male patients based on severity (mild, moderate, severe, and critical) were 15,02 ± 1,10, 14,20 ± 1,29, 14,14 ± 1,21, 14,50 ± 1,99 respectively (p<0.05); hemoglobin levels (g/dL) of female patients were 13,73 ± 0,94, 12,96 ± 0,76, 14,20 ± 1,27, 12,16 ±0,47 respectively (p<0,05); leukocyte count (/mm3) were 5600, 5950, 6250, 7850 respectively (p>0.05); absolute neutrophil count (103/µL) were 3.51, 3.79, 4.72, 6.56 respectively (p<0.05); absolute lymphocyte count (103/µL) were 1.67±0.60, 1.42±0.44, 1.14±0.44, 1.14±0.59, 1.06±0.65 respectively (p<0.05); eosinophil count (103/µL) were 0.058, 0.057, 0.031, 0.023 respectively (p>0.05); and platelet count (/mm3) were 251,000 ± 61,077, 229,522 ± 59,900, 173,071 ± 57,596, 133,350 ± 44,724, respectively (p<0.05). Conclusion: The conclusion of this study is that there are differences in hemoglobin levels, absolute neutrophils, absolute lymphocytes, and platelet counts between mild, moderate, severe, and critical COVID-19 patients.
KORELASI INDEKS MASSA TUBUH DENGAN GLUKOSA DARAH PUASA DAN KOLESTEROL PADA SKRINING KESEHATAN TENAGA KEPENDIDIKAN FAKULTAS KEDOKTERAN UNIVERSITAS ANDALAS Ramadhani, Jihan; Yulia, Dwi; Fasrini, Ulya Uti; Efrida, Efrida; Khaira, Fathiyyatul
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 3 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, September 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i3.1758

Abstract

Introduction. Non-communicable diseases as a cause of death in Indonesia are increasing. Hyperglycemia, hyperlipidemia, and obesity are some of the factors that contribute to an increased risk of non-communicable diseases. Education workers are a group of office workers who are at risk of obesity and non-communicable diseases because they have low physical activity. The study aimed to determine a correlation between body mass index with fasting blood glucose levels and total cholesterol levels in the health screening of educational staff faculty of medicine of Andalas University.  Methods. This research was an analytical study with a cross-sectional design using secondary data for the faculty of medicine of Andalas University health screening that was held on September 08, 2021. The tools used in the study were a calibrated glucometer to measure fasting blood glucose and a calibrated auto-check for total cholesterol examination. 37 data met the inclusion and exclusion criteria. Data were processed and analyzed using univariate and bivariate analysis using the Pearson correlation test.  Results. The result showed that the educational staff of the medical faculty of Andalas University are mostly in the late adult category, most are female and most of them are obese. The mean of body mass index is 25.3 kg/m2, the mean of fasting blood glucose level is 126.57 mg/dL and the mean of total cholesterol level is 205, 14 mg/dL. The bivariate analysis results showed no correlation between body mass index and fasting glucose levels (r = 0.316; p = 0.057) and no correlation between body mass index and total cholesterol levels (r = 0.091; p = 0.591). Conclusions. This study concludes that there is no correlation between body mass index with fasting blood glucose levels and total cholesterol levels in the health screening of educational staff faculty of medicine of Andalas University.
Hubungan Antara Jenis Paparan Radiasi Sinar-X dan Masa Kerja Dengan Kadar SGOT, SGPT, Ureum, dan Kreatinin Pada Pekerja Radiasi RSUP Dr. M. Djamil Padang Harahap, Endang Primawaty; Efrida, Efrida
Majalah Kedokteran Andalas Vol. 46 No. 3 (2023): Online Juli 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i4.p560-566.2023

Abstract

Latar Belakang: Interaksi radiasi sinar-X berupa ionisasi dan eksitasi terhadap materi yang dilewatinya,     menyebabkan perubahan DNA, sel, jaringan, dan organ. Jenis paparan (langsung, tidak langsung) dan masa kerja (5 tahun) memengaruhi efek paparan yang terjadi. Tujuan: Mengetahui hubungan antara jenis paparan radiasi sinar-X dan masa kerja dengan kadar SGOT, SGPT, ureum, dan kreatinin pekerja radiasi. Metode: Penelitian analitik rancangan potong lintang 56 pekerja radiasi RSUP Dr. M. Djamil Padang yang melakukan pemeriksaan SGOT, SGPT, ureum, dan kreatinin (Maret 2022). Data dianalisis dengan uji parametrik t tidak berpasangan, bermakna jika p<0,05. Hasil: Subjek penelitian 30 laki-laki (53,6%), 26 perempuan (46,4%), rerata umur 34 tahun (23-55 tahun). Distribusi frekuensi paparan langsung 32(57,1%), tidak langsung 24(42,9%). Kadar SGOT, SGPT, ureum, kreatinin paparan langsung berturut-turut 19,6U/L; 25,5U/L; 28,8mg/dL; 0,8mg/dL, paparan tidak langsung 18,3U/L; 20,9U/L; 27,8mg/dL; 0,8mg/dL. Tidak ditemukan perbedaan bermakna antar 2 kelompok (p>0,05). Pembahasan: Tidak terdapat hubungan paparan radiasi sinar-X dengan kadar SGOT, SGPT, ureum, dan kreatinin disebabkan dosis paparan dalam nilai batas dosis dan penerapan proteksi radiasi sesuai standar. Simpulan: Tidak terdapat perbedaan bermakna kadar SGOT, SGPT, ureum, dan kreatinin antara pekerja radiasi yang terpapar langsung dengan yang tidak terpapar langsung.
Effect of Dadih Probiotics on Malondialdehyde Levels in Diabetic Mellitus Rats With Alloxan Induction Fitriani, Indah; Efrida, Efrida
Majalah Kedokteran Andalas Vol. 46 No. 3 (2023): Online Juli 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i4.p517-525.2023

Abstract

Objective : This research aims to analyze the effect of dadih probiotics on MDA levels in alloxan-induced diabetic rats. Methods : This study used an experimental design with a post-test-only control group. Wistar strain white rat samples were divided into 4 groups. The negative group was not given any treatment, K(+), P1, and P2 were induced by alloxan 150 mg/kg BW on the first day. Groups P1 and P2 were given dadih probiotic doses of 1.87 g/200 gBW and 3.74 g/200 gBW on days 4 to 17. Results : Measurement of MDA levels was carried out on the 18th day. Data were analyzed with One Way Anova and a post-hoc test. The research results are statistically significant if p-value <0.05. The average levels of MDA K- 2.29 nmol/mL, K+ 3.77 nmol/mL, P1 2.97 nmol/mL, and P2 2.53 nmol/mL. Based on statistical tests, there was an effect of dadih probiotics on MDA levels as evidenced by a p-value < 0,05. Conclusion : Dadih probiotic doses of 1.87 g/200gBW and 3.74 g/200gBW can reduce MDA levels in rats.
Leukositosis, Neutrofilia, Radiologi Pneumonia, dan Usia Lanjut sebagai Faktor Risiko Derajat Kritis Pasien COVID-19 di Rumah Sakit Semen Padang : Studi Kasus Kontrol Efrida, Efrida
Majalah Kedokteran Andalas Vol. 46 No. 3 (2023): Supplementary July 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i5.p805-812.2023

Abstract

Latar Belakang: Pandemi Coronavirus Disease 2019 (COVID-19) disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), telah menyebabkan morbiditas dan mortalitas yang tinggi di seluruh dunia. Banyaknya kasus terkonfirmasi di seluruh dunia mendorong pemahaman komprehensif tentang faktor risiko COVID-19, sehingga dapat membantu pencegahan penyakit, perkembangan penyakit, dan hasil yang dapat merugikan pasien. Tujuan: Menganalisis faktor risiko yang berhubungan dengan derajat keparahan penyakit pasien COVID-19 di Rumah Sakit Semen Padang. Metode: Penelitian ini merupakan penelitian analitik observasional dengan pendekatan case-control menggunakan 100 data rekam medis pasien COVID-19 yang dirawat di Rumah Sakit Semen Padang pada tahun 2021. Parameter yang diperiksa berupa komorbid, rontgen foto toraks, dan parameter labor yaitu leukosit, neutrofil, limfosit, RNL, dan D-dimer. Teknik pengambilan sampel adalah consecutive sampling. Analisis bivariat menggunakan uji Chi-Square. Hasil dianggap bermakna jika nilai p<0,05. Hasil: Karakteristik pasien rawatan COVID-19: laki-laki sebanyak 51% dan perempuan 49%, kelompok umur lansia (>60 tahun) sebanyak 45%, 65% pasien memiliki komorbid, 63% pasien memiliki hasil pemeriksaan radiologi pneumonia. Hasil penelitian ini menunjukkan terdapat hubungan antara kelompok umur, hasil pemeriksaan radiologi, jumlah leukosit, dan jumlah neutrofil dengan derajat keparahan pasien COVID-19. Simpulan: Kelompok umur lansia, radiologi pneumonia, leukositosis, dan neutrofilia menjadi faktor risiko pasien COVID-19 derajat kritis di Rumah Sakit Semen Padang tahun 2021.
Sapta Cipta Rasa Tunggal Offering Dance at the 51st Dies Natalis of ISI Surakarta suharji, Suharji; Soemaryatmi, Soemaryatmi; Darmasti, Darmasti; Efrida, Efrida; Sumargono, Sumargono; Sukirman, Sri Ningsih
Gelar: Jurnal Seni Budaya Vol. 20 No. 2 (2022)
Publisher : Institut Seni Indonesia Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33153/glr.v20i2.4591

Abstract

This research is a case study of the performance of the offering dance at the ISI Surakarta 51st Dies Natalis Ceremony (held on July 15th, 2015) by seven dancers. The seven dancers previously acted as leaders of the Senate procession, after the members of the senate sat in their seats, they danced to express the character of Bima so that it could be said that the dance was part of the ceremonial event. The sesaji dance is an expression of Bima's character, which in Javanese collective knowledge is a complex system of symbols. This phenomenon is approached through the constructivism paradigm, especially from the point of view of interpretivism where the methodological mission is to elaborate a reflective events. The research question posed is what constitutes a gift or alms in the Sapta Cipta Rasa Tunggal – title of that dance — as offering dance considering that offerings lexico-etymologically means giving alms or charity. Triangulative data as objects of observation are videos of dance performances via the YouTube platform, interviews with source persons, and library data. The conclusions drawn are: 1) this sesaji dance is a form of mnemonic (kinetic mnemonic) in the form of motion as a tool for reflective memory; 2) offering dance and imitation of the imaginary character in the kind of the Bima containing doxa – knowledge that does not need to be verified – that the ethical attitudes that humans should have are teteg, tatag, teguh, tanggon, and tanggap.
Co-Authors Afsari, Nova Ali, Cindi Aulia Almurdi Almurdi Alzazira, Rara Aulia Amirah Zatil Izzah Andani Eka Putra Bakma, Isphandra Besri, Hanifa Zahra Darmasti, Darmasti Desywar, Desywar Dian Pertiwi Dwitya Elvira, Dwitya Efiariza, Nurul Navela Ellyza Nasrul Ety Yerizel Fathiyyatul Khaira, Fathiyyatul Fitria, Syarifah Tridani Fitrina, Dewi Wahyu Harahap, Endang Primawaty Hasmiwati Hendra Permana Herman, Deddy Husni Husni Indah Fitriani Khairunissa, Ica Lestari, Rahmi Malinda Meinapuri Mulya, Fiona Septi Oktavia, Nanda Prihandani, Tuty Puja, Annisa Fitria Rahmadina, Rahmadina Rahmatini . Ramadhani, Jihan Rismawati Yaswir Rudy Afriant Russilawati, Russilawati Sabebegen, Eka Musmita Sari, Kartika Aulia Siregar, Nazwa Nadira Soemaryatmi Soemaryatmi, Soemaryatmi Suharji Suharji Sukirman, Sri Ningsih Sumargono Trisuliandre, Muhammad Rizki Ulya Uti Fasrini Yulia, Dwi Yulistini, Yulistini Yusri Dianne Jurnalis Zahira, Aisyah Dhia Zelly Dia Rofinda