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Samitra, Dian
Universitas PGRI Silampari
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Journal : Jurnal Biosilampari: Jurnal Biologi

 1 
PENGARUH AIR REBUSAN DAUN HARENDONG BULU (Clidemia hirta) TERHADAP KADAR GULA DARAH MENCIT (Mus musculus) Okta Malia; Dian Samitra; Eka Lokaria
Jurnal Biosilampari : Jurnal Biologi Vol 3 No 1 (2020): Biosilampari
Publisher : LP4MK STKIP PGRI Lubuklinggau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31540/biosilampari.v3i1.966

Abstract

This study aims to determine the effect of the water boiled leaves of Clidemia hirta on blood sugar levels in Swiss Webster mice (Mus musculus). This research using a completely randomized design research design (CRD) with 5 treatment groups namely; Aquades control group (P0), 3 g sucrose treatment (P1), 3 g sucrose treatment + boiled bristle leaves boiled water at a dose of 0.13 ml/KgBB (P2), 3 g sucrose treatment + boiled bristle leaves boiled water at a dose of 0.26 ml/KgBB (P3), 3 g treatment of sucrose + boiled bristle leaves boiled water at a dose of 0.39 ml/KgBB (P4). Before administration of the extract, mice in the treatment groups P1, P2, P3 & P4 were induced using 3 g of sucrose for 5 days. Then after 5 days for groups P2, P3, and P4 followed by giving boiled water leaves for 7 days. The analysis result of One Way Anova Test shows that Fcount > Ftable (18.86 > 2.51). This shows the boiled water affects the blood sugar levels of male Swiss Webster mice. The concentration of extract at P4 (0.39 ml/KgBB) was more effective in reducing blood sugar levels.
PENGARUH AIR REBUSAN DAUN HARENDONG BULU (Clidemia hirta) TERHADAP KADAR KOLESTROL MENCIT (Mus musculus) Tuginah T; Dian Samitra; Eka Lokaria
Jurnal Biosilampari : Jurnal Biologi Vol 3 No 1 (2020): Biosilampari
Publisher : LP4MK STKIP PGRI Lubuklinggau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31540/biosilampari.v3i1.972

Abstract

This study aims to determine the effect of giving boiled water leaves Clidemia hirta on the levels of male webster swiss mice cholesterol. This type of research is an experimental study using the Completely Randomized Design (CRD) method which consists of 5 treatments with 5 repetitions. The experimental animals in this study were male mice which were divided into 5 groups namely P0 (aquadest), P1 (MDLT + PTU + boiled water 0.13 ml/bb), P2 (MDLT + PTU + boiled water 0.26 ml/bb), P3 (MDLT + PTU + boiled water 0.39 ml/bb), and P4 (Simvastatin 10 mg). The treatment was carried out using the gavage method using a gastric sonde device, giving boiled bristle leaves boiled water in the morning for 7 consecutive days carried out in the morning. Retrieval of blood cholesterol levels data by cutting the tail of mice and the next drop blood on the cholesterol strip Autocheck tool. Based on the results of the Kruskal Wallis test calculation states that Hcount <Htable (4.626 <9.49), it can be concluded that the provision of boiled water leaves of Clidemia hirta does no effect significant in reducing levels of male Swiss Webster mice (Mus musculus) cholesterol levels.
Co-Authors AA Sudharmawan, AA Aji , Nugroho Amelia, Wilda Andri Valen Arisandi, Desy Armi Yuneti Armi Yuneti Arum Setiawan Arum Setiawan Aulia Citra Bayumi, Nasrul Eka Lokaria Endang Suswati Endang Widi Winarni Erma Oktarina Erpita, Rosi Eryani, Rita Febrian, Aldi Ayang Fitria Lestari Hadiwinarto Hadiwinarto Harmoko Harmoko Harmoko Harmoko Harmoko Harmoko Harmoko Harmoko, Harmoko Herawati, Emi Indra Yustian Intan Puspita, Intan Joko Wiryono Joko Wiyono Kusnanto, R Angga Bagus M. Lutfi Firdaus Mahdi, Ibnu Mareta Widiya, Mareta Meti Yunita Miftahusalimah, Pingkan Luthfiyyah Muhammad Kristiawan Nopa Nopiyanti Novita , Dwi Novita Malasari Okta Malia Okta, Nellayuni Verdani Permadi, Adun Permata Sari, Dwi Alia R Angga Bagus Kusnanto Rambat Nur Sasongko Reny Dwi Riastuti Riastuty, Reny Dwi ROSMALINA, EEN Sanjaya S. Sari, Fatma Satinem Sepriyaningsih Sepriyaningsih Sepriyaningsih, Sepriyaningsih Septiana Septiana Septiana Setiawan, Feri Sonia Nopita Sari Sujarwo Sujarwo Tiara Yulisah Tio Gusti Satria Tuginah T Tuhim Setia Ulva Ulva, Tuhim Setia Wardianti, Yunita Yuli Febrianti YULIZAH, YENY Yuni Krisnawati Yuni Krisnawati Zico Fakhrur Rozi