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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Abdimasa Jurnal Ners Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Science Midwifery Jurnal Promotif Preventif Jurnal Kesehatan Tambusai International Journal of Health, Economics, and Social Sciences (IJHESS) Jurnal EduHealth Jurnal Ilmiah Ilmu Terapan Universitas Jambi Journal of Pharmaceutical and Sciences. Jurnal Etnofarmasi Science: Indonesian Journal of Science Jurnal Ilmu Kesehatan Jurnal Etnofarmasi
Angga Bayu Budiyanto
Universitas Pendidikan Muhammadiyah Sorong
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Hubungan Faktor Sosiodemografis dengan Kepuasan Pasien terhadap Pelayanan Kefarmasian di RSUD Fakfak Salsabilah, Juliandani; Budiyanto, Angga Bayu; Irwandi, Irwandi
Jurnal Promotif Preventif Vol 8 No 6 (2025): Desember 2025: JURNAL PROMOTIF PREVENTIF
Publisher : Fakultas Kesehatan Masyarakat Universitas Pancasakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47650/jpp.v8i6.2360

Abstract

Kepuasan pasien merupakan indikator penting dalam menilai mutu pelayanan rumah sakit. Penelitian ini bertujuan mengetahui hubungan faktor sosiodemografis dengan kepuasan pasien serta membandingkan tingkat kepuasan antara pasien rawat jalan BPJS dan Non-BPJS di RSUD Fakfak. Penelitian menggunakan metode analitik kuantitatif dengan desain cross-sectional. Data dikumpulkan menggunakan kuesioner SERVQUAL dan dianalisis dengan uji Chi-Square serta Mann-Whitney. Jumlah responden sebanyak 376 orang melalui perhitungan OpenEpi. Hasil Chi-Square menunjukkan tidak ada hubungan signifikan antara jenis kelamin, usia, pendidikan, pekerjaan, dan pendapatan dengan kepuasan (p>0,05), namun jarak tempat tinggal dan jenis asuransi berhubungan signifikan (p<0,05). Uji Mann-Whitney menunjukkan perbedaan signifikan antara pasien BPJS dan Non-BPJS (p<0,05), di mana pasien Non-BPJS lebih puas terutama pada dimensi tangible dan empathy
Formulasi dan Uji Aktivitas Antioksidan Sediaan Lip Balm Ekstrak Etanol Biji Alpukat (Persea americana Mill.) dengan Metode DPPH Syahrani, Anggi; Astuti, Ratih Arum; Budiyanto, Angga Bayu
Jurnal Promotif Preventif Vol 8 No 6 (2025): Desember 2025: JURNAL PROMOTIF PREVENTIF
Publisher : Fakultas Kesehatan Masyarakat Universitas Pancasakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47650/jpp.v8i6.2430

Abstract

Antioksidan merupakan senyawa yang mampu menetralkan radikal bebas, yaitu molekul reaktif yang berpotensi menimbulkan kerusakan sel dan memicu stres oksidatif. Biji alpukat (Persea americana Mill.) diketahui mengandung flavonoid, tanin, dan polifenol yang berperan sebagai antioksidan. Penelitian ini bertujuan memformulasikan ekstrak etanol biji alpukat ke dalam sediaan lip balm serta mengkaji sifat fisik dan aktivitas antioksidannya. Ekstrak diperoleh melalui metode maserasi menggunakan etanol 70% dan diformulasikan dalam konsentrasi 2%, 4%, dan 6%. Evaluasi yang dilakukan meliputi uji organoleptik, homogenitas, pH, daya sebar, daya lekat, stabilitas, serta pengujian aktivitas antioksidan dengan metode DPPH pada panjang gelombang 517 nm. Hasil penelitian menunjukkan bahwa seluruh formula memiliki konsistensi semi-solid yang stabil, homogen, pH sekitar 6, serta memenuhi kriteria fisik lip balm tanpa perubahan warna, aroma, atau bentuk selama penyimpanan. Uji aktivitas antioksidan menunjukkan bahwa F1 memiliki aktivitas sangat lemah dengan nilai IC₅₀ (555,64 µg/mL), F2 memiliki aktivitas sedang dengan IC₅₀ (161,32 µg/mL), dan F3 menunjukkan aktivitas kuat dengan IC₅₀ (61,73 µg/mL). Penelitian ini menyimpulkan bahwa ekstrak etanol biji alpukat dapat diformulasikan dengan baik dalam lipbalm, namun aktivitas antioksidannya menurun pada konsentrasi ekstrak yang lebih kecil.
Hubungan Karakteristik Sosiodemografi Terhadap Tingkat Kepuasan Pelayanan Kefarmasian di Apotek X Kota Sorong Diah Wulandari; Angga Bayu Budiyanto; Lukman Hardia
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.53162

Abstract

This study aims to determine the relationship between patient sociodemographic factors (age, gender, education, occupation, income,and travel distance) with satisfaction with pharmaceutical services at Pharmacy X, Sorong City. This study used a quantitative observational approach with a cross-sectional design and involved 181 respondents selected through a total sampling technique inthe period September - October 2025. Data collection was carried out using a questionnaire that had passed validity and reliability tests, and then analyzed using the chi-square. The results of the analysis showed that the variables of gender, age, education, occupation, and travel distance did not show a significant relationship with the level of satisfaction with pharmaceutical services (p> 0.05). Meanwhile, the income variable showed an important relationship with the level of satisfaction (p = 0.01). Overall, the levelof patient satisfaction on the five dimensions of Servqual was in the very satisfied category, especially on the dimensions of appearance, attention, and assurance. These findings illustrate that the quality of pharmaceutical services at Pharmacy X, SorongCity, is already very good, but there are differences in perceptions of satisfaction among patients with different income levels. Theresults of this study are expected to provide input for pharmacies to continuously improve service quality
Antibacterial Effectiveness Test of Wrap Leaf Extract (Smilax rotundifolia) Against Escherichia coli and Propionibacterium acnes Bacteria Heti Aisyah; Irwandi Irwandi; Angga Bayu Budiyanto; A.M. Muslihin
Jurnal Penelitian Pendidikan IPA Vol 11 No 4 (2025): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i4.10699

Abstract

Diarrhea and acne, caused by the bacteria Escherichia coli and Propionibacterium acnes, are common illnesses in children and adults. Antibiotics can overcome bacterial infections, but cases of antibiotic resistance are increasing. This study aims to determine the effect of wrap leaf extract (Smilax rotundifolia) on the growth of P. acnes and E. coli. This research can support microbiology-based science learning that utilizes biodiversity for students. Phytochemical tests showed that the extract contained flavonoids, alkaloids and saponins. The results of antibacterial testing showed that wrap leaf extract was able to inhibit the growth of P. acnes bacteria from concentrations of 10% and 15% with an average inhibition of 5.31 mm and 6.42 mm, and the positive control (Amoxicillin) had an inhibition of 7.26 mm. However, E. coli did not show any inhibition zone. The Mann-Whitney test results showed that the wrapper leaf extract has antibacterial effectiveness by comparing the negative control with a concentration of 10% and 15% and the positive control with a concentration of 10%. There is a difference between the concentration comparison where the Sig.<0.05 value. Then, comparing the positive control with a concentration of 15% produces a Sig.>0.05 value, meaning there is no difference between the two.
Analgesic Activity Test of Carrot (Daucus carota L.) Peel Extract on White Mice Rahayu, Lintang Kumala; Ratih Arum Astuti; Angga Bayu Budiyanto
Jurnal EduHealth Vol. 16 No. 04 (2025): Jurnal EduHealt, Edition October-December , 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pain is an unpleasant experience characterized by potential tissue damage. One plant that has the potential to inhibit pain through its chemical compounds, namely flavonoids and alkaloids, is carrot peel (Daucus carota L.). The purpose of this study was to determine the analgesic activity of carrot peel extract in male mice. Carrot peel was extracted using the maceration method with 96% solvent. This study used 15 mice as test animals, which were divided into 5 treatment groups, namely the negative control group (CMC-Na), the positive control group (Sodium Diclofenac), carrot peel extract 100 mg/kgBW, 150 mg/kgBW, and 200 mg/kgBW. The test was conducted using the tail flick method with an analgesia measuring device. The test was conducted using the tail flick method with an analgesia measuring device. The data obtained were then analyzed using a paired sample t-test. The results showed that the three doses of carrot peel ethanol extract, 100 mg/kgBW, 150 mg/kgBW, and 200 mg/kgBW, did not have analgesic activity in male mice.
Analgesic effectiveness test of kitolod leaf ethanol extract (isotoma longiflora l.) against male white mice (mus musculus) Yanti, Inda Dwi; Budiyanto, Angga Bayu; Hardia, Lukman
Science Midwifery Vol 13 No 6 (2026): February: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i6.2227

Abstract

This study aims to evaluate the analgesic effectiveness of ethanol extract of Kitolod leaves (Isotoma longiflora L.) in male white mice (Mus musculus). Kitolod leaves are traditionally used as herbal remedies for pain, yet scientific evidence regarding their analgesic potential remains limited. This true experimental research employed a pre- and post-test with control group design, involving five groups: negative control (Na-CMC 1%), positive control (diclofenac sodium 50 mg), and three treatment groups administered Kitolod leaf extract at doses of 56 mg/kgBW, 112 mg/kgBW, and 224 mg/kgBW. Extract preparation was carried out using maceration with 96% ethanol, followed by phytochemical screening which confirmed the presence of flavonoids, alkaloids, tannins, and steroids. Analgesic activity was assessed using the tail flick method by measuring latency response to thermal stimuli at intervals of 30, 60, 90, 120, 150, and 180 minutes post-treatment. The results showed that Kitolod leaf extract increased pain response latency, with the 112 mg/kgBW and 224 mg/kgBW doses demonstrating the strongest analgesic effects comparable to diclofenac sodium. Statistical analysis using independent sample t-test and one-way ANOVA indicated significant differences (p < 0.05) between treatment and control groups. These findings suggest that Kitolod leaf ethanol extract possesses promising analgesic properties and may serve as a potential natural alternative for pain management.
EVALUASI POLA PERESEPAN OBAT ANTI HIPERTENSI Di PUSKESMAS Aulia Mifthakul Jannah; Lukman Hardia; Angga Bayu Budiyanto
JURNAL ETNOFARMASI Vol. 1 No. 01 (2023): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v1i01.1722

Abstract

Kriteria pemakaian obat secara rasional meliputi tepat diagnosa, tepat indikasi penyakit, tepat pemilihan obat, tepat pasien, tepat dosis, tepat cara pemakaian, tepat interval waktu pemberian, tepat lama pemberian, serta waspada terhadap efek samping. Evaluasi peresepan obat penting dilakukan untuk mengetahui dan memastikan bahwa pasien telah menerima pengobatan yang sesuai dengan kebutuhan klinisnya, dalam dosis dan jangka waktu yang sesuai, dan dengan biaya terendah. Ketidakrasionalan peresepan masih sering ditemukan terutama di Puskesmas yang merupakan pusat pelayanan kesehatan tingkat 1, dimana obat dan dosis yang diresepkan oleh tenaga medis kurang sesuai akibat ketersediaan obat yang terbatas, dan salah satunya adalah obat hipertensi. Sehingga perlu dilakukan evaluasi pola peresepan obat antihipertensi di Puskesmas Mariat Kabupaten Sorong periode Juli – September 2022. Penelitian ini bertujuan Untuk mengevaluasi pola peresepan obat anti-hipertensi di Puskesmas Mariat Kabupaten Sorong. Penelitian ini menggunakan rekam medis sebanyak 63 resep. Hasil penelitian Evaluasi Peresepan obat Antihipertensi Di Puskesmas Mariat Kabupaten Sorong Periode Juli-September 2022 bahwa tepat obat sebanyak 100% tepat pasien sebanyak 100% tepat dosis sebanyak 100%, tepat interval waktu pemberian sebanyak 88,46%. Obat Antihipertensi yang diberikan kepada pasien adalah terapi kombinasi golongan CCB+ACEI (amlodipin + captopril) dengan persentase yaitu 25% dan selanjutnya monoterapi amlodipin sebanyak 75%, dan captopril sebanyak 0%.
PENETAPAN KADAR SARI LARUT AIR, KADAR SARI LARUT ETANOL DAN IDENTIFIKASI ALKALOID PADA EKSTRAK ETANOL 96% DAUN KERSEN (Muntingia calabura L.) A.M. Muslihin; Angga Bayu Budiyanto
JURNAL ETNOFARMASI Vol. 1 No. 02 (2022): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v1i02.1725

Abstract

Kersen (Muntingia calabura L.) merupakan salah satu jenis tanaman yang tumbuh baik di daerah tropis seperti Indonesia. Pohon kersensangat mudah tumbuh tanpa penanaman khusus seperti tempat terbuka, perbukitan, hingga tepi-tepi jalan. Daun kersen juga memilikiberbagai kandungan seperti senyawa flavonoid, tannin, triterpene, saponin, polifenol yang menunjukkan adanya aktivitas antioksidan. Pada penelitian ini dilakukan penetapan kadar sari pada simplisia daun kersen menggunakan 2 jenis pelarut yaitu air dan etanol 96%dan simplisia sebanyak 5 gram pada masing masing pelarut. Berdasarkan hasil yang didapatkan kadar sari larut etanol mendapatkanhasil sebanyak 0,16% dan kadar sari larut air mendapatkan hasil sebanyak 0,96%. Penelitian ini juga dilakukan identifikasi alkaloid dan hasilnya menunjukkan bahwa Ekstrak Etanol daun Kersen (Muntingia calabura L.) positif mengandung Alkaloid.
PENETAPAN KADAR FENOLIK TOTAL EKSTRAK ETANOL 70% PELEPAH PISANG AMBON (Musa paradisiaca Var. Sapientum) DARI KABUPATEN SORONG, PAPUA BARAT Mohammad Usman Nur; Ratih Arum Astuti; Angga Bayu Budiyanto; Irwandi Irwandi
JURNAL ETNOFARMASI Vol. 1 No. 02 (2022): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v1i02.1727

Abstract

Penelitian terkait pemanfaatan limbah sudah banyak dilakukan, salah satunya pelepah pisang ambon. Ekstrak etanol pelepah pisang ambon terbukti memiliki efek farmakologi salah satunya sebagai penyembuh luka. Untuk mengetahui tingkat keamanan dan efektivitas sediaan ekstrak pelepah pisang ambon, maka perlu dilakukan beberapa uji spesifik dan non spesifik sebagai upaya untuk menjaga kualitas mutu. Penelitian ini bertujuan mengetahui parameter spesifik yaitu penetapan kadar total fenol ekstrak etanol pelepah pisang ambon dari Kabupaten Sorong, Papua Barat. Penelitian ini termasuk jenis penelitian non eksperimental. Metode ekstraksi yang digunakan adalah maserasi dengan pelarut etanol 70%. Uji parameter spesifik berupa kadar fenolik total dengan analisis kualitatif menggunakan uji tabung dan uji KLT serta analisis kuantitatif menggunakan Spektrofotometer UV-Vis masing-masing dengan pereaksi Folin-Ciocalteu. Hasil penelitian parameter spesifik ekstrak etanol pelepah pisang ambon dari kabupaten Sorong, Papua Barat adalah sebagai berikut: hasil uji tabung dan uji KLT menunjukkan bahwa ekstrak etanol pelepah pisang ambon mengandung senyawa fenolik, flavonoid, tanin, dan saponin ; hasil penetapan kadar berupa kadar fenolik total sebesar 15,42 ± 0,159 mg GAE/g ekstrak. Parameter standar umum ekstrak tanaman obat berupa parameter spesifik uji kandungan kimia ekstrak pada penelitian ini secara umum telah memenuhi ketentuan yang ditetapkan oleh Farmakope Herbal Indonesia.
ANALISIS GUGUS FUNGSI SERTA PENETAPAN KADAR TOTAL FLAVONOID DAN ALKALOID PADA EKSTRAK PAKIS MERAH (Stenochlaena palutris) Angga Bayu Budiyanto; Wa Siti Arabiya
JURNAL ETNOFARMASI Vol. 3 No. 01 (2025): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v3i01.1987

Abstract

This study aimed to evaluate the effectiveness of three extraction methods (maceration, soxhletation, and reflux) in obtaining bioactive compounds from Red Fern (Stenochlaena palutris), which is known to have therapeutic potential. The methods used included cold extraction (maceration) and hot extraction (soxhletation, reflux) with ethanol solvent, which was chosen because of its ability to dissolve polar and nonpolar compounds. The maceration method produced the highest yield of 15.4002% with extraction for 72 hours without heating, which maintained the stability of the active compounds. In contrast, the soxhletation and reflux methods produced yields of 2% and 10%, respectively, possibly due to degradation of the active compounds due to heating. Phytochemical screening showed the presence of alkaloids, flavonoids, tannins, saponins, steroids, and terpenoids in the resulting extracts. FTIR assay identified various important functional groups such as hydroxyl (-OH), alkanes, and C-O in all extraction methods. and the determination of the total alkaloid content obtained was 1.066335% while the total flavonoid content obtained was 4.652425%. So from the data it can be seen that the total Flavonoid compound is greater than the Alkaloid compound
Co-Authors A. M. Muslihin Achmad Noerkhaerin Putra Anggraini Palino Anisa, Meilinda Aponno, Alyssa Mileta Astuti, Ratih Arum Aulia Mifthakul Jannah Carmel Josuhua Paulus Diah Wulandari Fabanyo, Syahrul H. Fajar Maulana . Heti Aisyah Heti Aisyah Indah Amelia Rizky Indah Amelia Rizky Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Jannah, Aulia Mifthakul Lukman Hardia M. Yogi Riyantama Isjoni Maulana, Fajar MIFTAHUL JANNAH Mohammad Usman Nur Ngodihu, Muhammad Syafinuddin Almandari Nur Indah Sari Nur ‘Azah Nur, Mohammad Usman nurjanah, sartika wahyu Nurwahyuni Ona Bugis Tehuayo Pasulu, Yusran Timang Pratama, Agus Sangka Rahayu, Lintang Kumala Rahayu, Mellawati Yuningtyas Rohmania, Siti Rossardy, Marzella Dea Salim, Fathiyah Salsabilah, Juliandani Siska Siska Syahrani, Anggi Taran, Kris Theisalexander ulandari, clarista windi Utami, Hikmahtul Putri Wa Siti Arabiya WaOde Suriani Watora, Wahyuni Yanti, Inda Dwi Yuniatri, Nur Khusna yunus, sri ulan dari