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Angga Bayu Budiyanto
Fakultas Sains Terapan Universitas Pendidikan Muhammadiyah Sorong
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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ANALISIS GUGUS FUNGSI SERTA PENETAPAN KADAR TOTAL FLAVONOID DAN ALKALOID PADA EKSTRAK PAKIS MERAH (Stenochlaena palutris) Angga Bayu Budiyanto; Wa Siti Arabiya
JURNAL ETNOFARMASI Vol. 3 No. 01 (2025): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v3i01.1987

Abstract

This study aimed to evaluate the effectiveness of three extraction methods (maceration, soxhletation, and reflux) in obtaining bioactive compounds from Red Fern (Stenochlaena palutris), which is known to have therapeutic potential. The methods used included cold extraction (maceration) and hot extraction (soxhletation, reflux) with ethanol solvent, which was chosen because of its ability to dissolve polar and nonpolar compounds. The maceration method produced the highest yield of 15.4002% with extraction for 72 hours without heating, which maintained the stability of the active compounds. In contrast, the soxhletation and reflux methods produced yields of 2% and 10%, respectively, possibly due to degradation of the active compounds due to heating. Phytochemical screening showed the presence of alkaloids, flavonoids, tannins, saponins, steroids, and terpenoids in the resulting extracts. FTIR assay identified various important functional groups such as hydroxyl (-OH), alkanes, and C-O in all extraction methods. and the determination of the total alkaloid content obtained was 1.066335% while the total flavonoid content obtained was 4.652425%. So from the data it can be seen that the total Flavonoid compound is greater than the Alkaloid compound
Studi Fitokimia Senyawa Aktif Ekstrak Batang Nelambo suon (Rubiaceae) Rossardy, Marzella Dea; Muslihin, A.M.; Watora, Wahyuni; Budiyanto, Angga Bayu; Hardia, Lukman; Irwandi, Irwandi; Aponno, Alyssa Mileta; Utami, Hikmahtul Putri
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1333

Abstract

Background: Papua has high biodiversity with significant potential as a source of traditional medicinal plants, including Nelambo suon (Rubiaceae), which has been empirically used by local communities. However, scientific information regarding the active compounds in its stem bark remains limited. Objective: This study aimed to identify the secondary metabolite groups present in the ethanol extract of Nelambo suon stem bark through phytochemical screening. Methods: The research was conducted experimentally using the maceration method with 80% ethanol as the solvent. The stem bark simplicia was extracted and qualitatively screened for alkaloids, flavonoids, tannins, and saponins using specific reagents. Results: The results showed that the ethanol extract of Nelambo suon stem bark contained alkaloids, flavonoids, tannins, and saponins, indicated by characteristic color changes, precipitate formation, and foam production. Conclusion: These findings suggest that Nelambo suon stem bark is a potential source of bioactive compounds and may be further developed as a herbal medicinal material based on local wisdom.
AKTIVITAS SPF LOTION KOMBINASI EKSTRAK RUMPUT LAUT (EUCHEUMA COTTONI) DAN EKSTRAK LIDAH BUAYA (ALOE VERA) yunus, sri ulan dari; Budiyanto, Angga Bayu; Astuti, Ratih Arum
Jurnal Kesehatan Tambusai Vol. 7 No. 1 (2026): MARET 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v7i1.56520

Abstract

Paparan sinar ultraviolet (UV) yang berlebihan dapat meneyebabkan kerusakan kulit sehingga diperlukan sediaan tabir surya yang aman dan efektif. Rumput laut (Eucheuma cottoni) dan lidah buaya (Aloe vera) memiliki zat bioaktif alami yang bisa melindungi kulit dari sinar matahari. Penelitian ini membuat lotion tabir surya dari campuran ekstrak etanol 95% rumput laut dan 96% lidah buaya. Tujuannya adalah merancang lotion, memeriksa sifat fisik dan ketahanannya, serta mengukur nilai Sun Protection Factor (SPF) secara in vitro. Lotion diformulasikan menjadi tiga formula dengan kadar ekstrak berbeda. Pemeriksaan fisik meliputi uji organoleptik, homogenitas, pH, daya sebar, daya lekat, dan viskositas sebelum serta sesudah uji stabilitas dengan metode cycling test. Analisis statistikmenggunakan uji paired t-test menunjukkan tidak terdapat perbedaan yang signifikan (p > 0,05) pada seluruh parameter fisik, sehingga sediaan dinyatakn stabil. Penentuan nilai SPF dilakukan dengan metode spektrofotometer UV-Vis pada panjang gelombang 290-320 nm dan dianalisis secara deskriptif. Nilai SPF pada formula I 3,1 formula II 4,5 dan formula III 6,21. Hasil menunjukkan Formula III memiliki nilai SPF tertinggi.
Anti-inflammatory Activity Test of Red Pucuk Leaf Extract Against (Syzygium myrtifolium Walp) White Rats (Rattus norvegicus) Tehuayo, Ona Bugis; Angga Bayu Budiyanto; Irwandi, Irwandi
Jurnal EduHealth Vol. 17 No. 01 (2026): Jurnal EduHealt, January-March 2026
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The plant S. myrtifolium Walp, also known as red shoots, is an ornamental plant with characteristic red easy leaves and green old leaves. This plant is known to contain active compounds that have potential as pharmacological agents, especially anti-inflammatory. The purpose of this study was to identify the anti-inflammatory activity of ethanol extract of red shoot leaves (S. myrtifolium Walp) against white rats (Rattus norvegicus) using several dose variations. The population in this study was the red shoots leaf plant (Syzygium myrtifolium Walp) obtained from Mariat Pantai Village, Sorong Regency. While the samples used in this study were red shoot leaves (Syzygium myrtifolium Walp) which were taken fresh green leaves. The results of phytochemical analysis identified the presence of alkaloid, flavonoid, tannin, saponin and phenol compounds. The test data were analyzed using ANOVA method followed by Paired Sample T test and LSD test to determine the presence and absence of differences from before treatment and after treatment. The test results showed that red shoot leaf extract has anti-inflammatory activity against white rats significantly at doses of 200 mg / kg BW, 300 mg / kgBB and 450 mg / kgBB.
Co-Authors A. M. Muslihin Achmad Noerkhaerin Putra Anggraini Palino Anisa, Meilinda Aponno, Alyssa Mileta Astuti, Ratih Arum Aulia Mifthakul Jannah Fabanyo, Syahrul H. Fajar Maulana . Heti Aisyah Heti Aisyah Indah Amelia Rizky Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Jannah, Aulia Mifthakul Lukman Hardia M. Yogi Riyantama Isjoni Maulana, Fajar MIFTAHUL JANNAH Mohammad Usman Nur Ngodihu, Muhammad Syafinuddin Almandari Nur Indah Sari Nur ‘Azah Nur, Mohammad Usman nurjanah, sartika wahyu Nurwahyuni Pasulu, Yusran Timang Pratama, Agus Sangka Rahayu, Lintang Kumala Rahayu, Mellawati Yuningtyas Rizky, Indah Amelia Rohmania, Siti Rossardy, Marzella Dea Salim, Fathiyah Salsabilah, Juliandani Siska Siska Syahrani, Anggi Tehuayo, Ona Bugis ulandari, clarista windi Utami, Hikmahtul Putri Wa Ode Suriani Wa Siti Arabiya Watora, Wahyuni Yanti, Inda Dwi Yuniatri, Nur Khusna yunus, sri ulan dari