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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Abdimasa Jurnal Ners Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Science Midwifery Jurnal Promotif Preventif Jurnal Kesehatan Tambusai International Journal of Health, Economics, and Social Sciences (IJHESS) Jurnal EduHealth Jurnal Ilmiah Ilmu Terapan Universitas Jambi Journal of Pharmaceutical and Sciences. Jurnal Etnofarmasi Science: Indonesian Journal of Science Jurnal Ilmu Kesehatan Jurnal Etnofarmasi
Angga Bayu Budiyanto
Universitas Pendidikan Muhammadiyah Sorong
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Studi Fitokimia Senyawa Aktif Ekstrak Batang Nelambo suon (Rubiaceae) Rossardy, Marzella Dea; Muslihin, A.M.; Watora, Wahyuni; Budiyanto, Angga Bayu; Hardia, Lukman; Irwandi, Irwandi; Aponno, Alyssa Mileta; Utami, Hikmahtul Putri
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1333

Abstract

Background: Papua has high biodiversity with significant potential as a source of traditional medicinal plants, including Nelambo suon (Rubiaceae), which has been empirically used by local communities. However, scientific information regarding the active compounds in its stem bark remains limited. Objective: This study aimed to identify the secondary metabolite groups present in the ethanol extract of Nelambo suon stem bark through phytochemical screening. Methods: The research was conducted experimentally using the maceration method with 80% ethanol as the solvent. The stem bark simplicia was extracted and qualitatively screened for alkaloids, flavonoids, tannins, and saponins using specific reagents. Results: The results showed that the ethanol extract of Nelambo suon stem bark contained alkaloids, flavonoids, tannins, and saponins, indicated by characteristic color changes, precipitate formation, and foam production. Conclusion: These findings suggest that Nelambo suon stem bark is a potential source of bioactive compounds and may be further developed as a herbal medicinal material based on local wisdom.
AKTIVITAS SPF LOTION KOMBINASI EKSTRAK RUMPUT LAUT (EUCHEUMA COTTONI) DAN EKSTRAK LIDAH BUAYA (ALOE VERA) yunus, sri ulan dari; Budiyanto, Angga Bayu; Astuti, Ratih Arum
Jurnal Kesehatan Tambusai Vol. 7 No. 1 (2026): MARET 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v7i1.56520

Abstract

Paparan sinar ultraviolet (UV) yang berlebihan dapat meneyebabkan kerusakan kulit sehingga diperlukan sediaan tabir surya yang aman dan efektif. Rumput laut (Eucheuma cottoni) dan lidah buaya (Aloe vera) memiliki zat bioaktif alami yang bisa melindungi kulit dari sinar matahari. Penelitian ini membuat lotion tabir surya dari campuran ekstrak etanol 95% rumput laut dan 96% lidah buaya. Tujuannya adalah merancang lotion, memeriksa sifat fisik dan ketahanannya, serta mengukur nilai Sun Protection Factor (SPF) secara in vitro. Lotion diformulasikan menjadi tiga formula dengan kadar ekstrak berbeda. Pemeriksaan fisik meliputi uji organoleptik, homogenitas, pH, daya sebar, daya lekat, dan viskositas sebelum serta sesudah uji stabilitas dengan metode cycling test. Analisis statistikmenggunakan uji paired t-test menunjukkan tidak terdapat perbedaan yang signifikan (p > 0,05) pada seluruh parameter fisik, sehingga sediaan dinyatakn stabil. Penentuan nilai SPF dilakukan dengan metode spektrofotometer UV-Vis pada panjang gelombang 290-320 nm dan dianalisis secara deskriptif. Nilai SPF pada formula I 3,1 formula II 4,5 dan formula III 6,21. Hasil menunjukkan Formula III memiliki nilai SPF tertinggi.
Anti-inflammatory Activity Test of Red Pucuk Leaf Extract Against (Syzygium myrtifolium Walp) White Rats (Rattus norvegicus) Ona Bugis Tehuayo; Angga Bayu Budiyanto; Irwandi Irwandi
Jurnal EduHealth Vol. 17 No. 01 (2026): Jurnal EduHealt, January-March 2026
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The plant S. myrtifolium Walp, also known as red shoots, is an ornamental plant with characteristic red easy leaves and green old leaves. This plant is known to contain active compounds that have potential as pharmacological agents, especially anti-inflammatory. The purpose of this study was to identify the anti-inflammatory activity of ethanol extract of red shoot leaves (S. myrtifolium Walp) against white rats (Rattus norvegicus) using several dose variations. The population in this study was the red shoots leaf plant (Syzygium myrtifolium Walp) obtained from Mariat Pantai Village, Sorong Regency. While the samples used in this study were red shoot leaves (Syzygium myrtifolium Walp) which were taken fresh green leaves. The results of phytochemical analysis identified the presence of alkaloid, flavonoid, tannin, saponin and phenol compounds. The test data were analyzed using ANOVA method followed by Paired Sample T test and LSD test to determine the presence and absence of differences from before treatment and after treatment. The test results showed that red shoot leaf extract has anti-inflammatory activity against white rats significantly at doses of 200 mg / kg BW, 300 mg / kgBB and 450 mg / kgBB.
Analis Kualitatif Senyawa Formalin pada Mie Basah Diwarung Bakso Kabupaten Sorong WaOde Suriani; Ratih Arum Astuti; Angga Bayu Budiyanto
Science: Indonesian Journal of Science Vol. 2 No. 1 (2025)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/science.v2i1.263

Abstract

Mie basah merupakan produk makanan yang cukup banyak dikonsumsi oleh masyarakat. Mie basah mengandung kadar air sekitar 52-60%, yang cukup tinggi, sehingga menyebabkan mie tidak bertahan lama dalam penyimpanannya. Hal ini mendorong produsen yang tidak bertanggung jawab untuk menambahkan zat pengawet berbahaya, yaitu formalin, agar mie memiliki masa simpan yang lebih lama.Penelitian ini bertujuan untuk mengetahui ada tidaknya senyawa formalin pada mie basah di wilayah Aimas dan Mariat. Metode yang digunakan dalam penelitian ini adalah analisis kualitatif dengan pereaksi nash. Pengambilan sampel dilakukan dengan metode sampling jenuh karena sampel kurang dari 30. Penelitian ini dilaksanakan di Laboratorium Terpadu Universitas Pendidikan Muhammadiyah Sorong.Hasil penelitian yang dilakukan pada 27 sampel mie basah yang beredar di wilayah Kabupaten Sorong menunjukkan tidak terjadinya perubahan warna pada filtrat sampel yang telah ditambahkan pereaksi nash. Oleh karena itu, dapat ditarik kesimpulan bahwa mie basah yang beredar di wilayah Kabupaten Sorong tidak mengandung formalin. Hal ini menunjukkan bahwa mie basah telah memenuhi syarat mutu SNI 2987:2015.
Evaluasi Manajemen Penyimpanan Obat Berdasarkan Standar Pelayanan Farmasi: Studi Observasional Deskriptif di Rumah Sakit Daerah Kabupaten Sorong Taran, Kris Theisalexander; Budiyanto, Angga Bayu; Irwandi, Irwandi
Jurnal Promotif Preventif Vol 9 No 2 (2026): April 2026: JURNAL PROMOTIF PREVENTIF
Publisher : Fakultas Kesehatan Masyarakat Universitas Pancasakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47650/jpp.v9i2.2610

Abstract

Penyimpanan obat yang memenuhi standar memiliki peranan penting dalam menjamin kualitas serta keselamatan pelayanan kefarmasian di rumah sakit. Penyimpanan yang tidak tepat dapat menyebabkan kerusakan obat dan meningkatkan risiko kesalahan penggunaan. Penelitian ini bertujuan untuk menilai sistem penyimpanan obat di Instalasi Farmasi RSUD Kabupaten Sorong. Metode penelitian yang diterapkan adalah deskriptif observasional dengan teknik pengumpulan data berupa lembar observasi yang berisi indikator penyimpanan sediaan farmasi berdasarkan parameter indicator permenkes nomor 72 tahun 2016 tentang standar pelayanan kefarmasian di rumah sakit. Hasil penelitian menunjukkan secara keseluruhan telah memenuhi standar yang berlaku, termasuk persyaratan penyimpanan obat di gudang 83%, sarana penyimpanan 100%, metode penyimpanan 83,3%, komponen penyimpanan 100% dan kesesuaian penyimpanan obat emergensi 100%.
Efficacy of Akway (Drymis sp.) Bark Extract in Restoring Hemoglobin Levels: A Preclinical Study in a Sodium Nitrite-Induced Anemia Mice Model Lukman Hardia; Fabanyo, Syahrul H.; Budiyanto, Angga Bayu; Muslihin, A. M.; Rossardy, Marzella Dea; Irwandi, Irwandi; Watora, Wahyuni
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 11 No. 1 (2026)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v11i1.44062

Abstract

The high prevalence of anemia prompted us to explore the potential of local herbs in Papua, Indonesia, which is known for its rich natural resources. In this study, we aim to conduct preclinical tests on anemia model test animals to validate the effectiveness of akway bark extract (ABE) as the basis for the development of effective and safe herbal antianemia drugs in the future. This study employs a quantitative analytical approach, utilizing an experimental design with a pre-posttest with a control group design. The research sample used 20 mice test animals, divided into 5 groups consisting of 4 animals each, namely: the control group (positive and negative), and the intervention group using ABE doses of 10, 30, and 50mg/kg. This study was approved by the Health Research Ethics Committee of STIFAR Makassar (Number: 299/EC.1.1.B/III/KEPK/2024). Data analysis showed that a 14-day intervention using ABE was able to increase Hb levels (D% = 52.00±27.13 [ABE dose 10mg/kg]; 49.72±7.86 [ABE dose 50mg/kg] and 42.82±12.75 [ABE dose 30mg/kg]) significantly (p<0.05) when compared with the negative control (D% = 4.54±5.14), but when compared with the positive control (D% = 52.57±10.85) the average increase in Hb levels was not significant (p>0.05). In conclusion, our study showed that mice of the anemia model, intervened using ABE at doses of 10, 30, and 50mg/kg once daily for 14 days, experienced increased Hb levels.
Anthocyanin Compounds from Ethanol Extract of Red Fruit (Pandanus conideus L.): A Functional Group Analysis Indah Amelia Rizky; Angga Bayu Budiyanto; Lukman Hardia
Jurnal Penelitian Pendidikan IPA Vol 10 No 11 (2024): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i11.9321

Abstract

Red Fruit (Pandanus conoideus L.) is a typical Papuan plant that is rich in bioactive compounds such as anthocyanins, which have the potential to act as antioxidants. This research aims to analyze the chemical structure of anthocyanin compounds from red fruit ethanol extract using Fourier Transformed Infrared (FTIR) spectroscopy. FTIR is a spectroscopic tool widely used to characterize or detect functional groups and qualitatively identify compounds in samples. Anthocyanins act as antioxidants and have various biological activities such as preventing cancer, cardiovascular disease, and diabetes. Extraction was carried out using the maceration method using 70% ethanol solvent, and characterization was performed using FTIR in the wave range 4000-450 cm⁻¹. The results of the research that has been carried out show that the ethanol extract of red fruit contains secondary metabolites such as flavonoids, alkaloids, and saponins. The FTIR results of red fruit extract show the presence of functional groups characterized by the presence of the O-H, C-O-C, C-O, and C=C functional groups which are important indicators of the antioxidant properties of anthocyanins. This research confirms the potential of Red Fruit as a natural source of anthocyanins which are useful as antioxidants
Analysis of administrative-pharmaceutical completeness on patient prescriptions at Puskesmas X, Sorong City Carmel Josuhua Paulus; Lukman Hardia; Angga Bayu Budiyanto
Science Midwifery Vol 14 No 2 (2026): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i2.2374

Abstract

Prescription completeness is an important indicator in pharmaceutical services because it is related to therapeutic accuracy and patient safety. Incomplete prescriptions may increase the risk of medication errors during drug preparation and administration. This study aimed to determine the level of administrative and pharmaceutical completeness of patient prescriptions at Puskesmas X, Sorong City. This research used a descriptive observational method with a retrospective approach involving 1,572 patient prescriptions selected using a total sampling technique. The assessment was conducted based on the standards of the Indonesian Ministry of Health Regulation Number 73 of 2016 and Number 58 of 2014. The results showed that all prescriptions (100%) were categorized as incomplete. In the administrative aspect, patient name and prescription date reached 100% completeness, while patient height, doctor’s practice license number, and doctor’s phone number showed 0% completeness. Doctor’s initials/signature were found in 60.8% of prescriptions. In the pharmaceutical aspect, drug name, stability, and compatibility reached 100% completeness, while dosage form and drug strength reached 70.6% and 69.3%, respectively. The study concluded that pharmaceutical completeness was better than administrative completeness; however, prescription writing at Puskesmas X, Sorong Citis still, did not meet pharmaceutical service standards.
Co-Authors A. M. Muslihin Achmad Noerkhaerin Putra Anggraini Palino Anisa, Meilinda Aponno, Alyssa Mileta Astuti, Ratih Arum Aulia Mifthakul Jannah Carmel Josuhua Paulus Diah Wulandari Fabanyo, Syahrul H. Fajar Maulana . Heti Aisyah Heti Aisyah Indah Amelia Rizky Indah Amelia Rizky Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Jannah, Aulia Mifthakul Lukman Hardia M. Yogi Riyantama Isjoni Maulana, Fajar MIFTAHUL JANNAH Mohammad Usman Nur Ngodihu, Muhammad Syafinuddin Almandari Nur Indah Sari Nur ‘Azah Nur, Mohammad Usman nurjanah, sartika wahyu Nurwahyuni Ona Bugis Tehuayo Pasulu, Yusran Timang Pratama, Agus Sangka Rahayu, Lintang Kumala Rahayu, Mellawati Yuningtyas Rohmania, Siti Rossardy, Marzella Dea Salim, Fathiyah Salsabilah, Juliandani Siska Siska Syahrani, Anggi Taran, Kris Theisalexander ulandari, clarista windi Utami, Hikmahtul Putri Wa Siti Arabiya WaOde Suriani Watora, Wahyuni Yanti, Inda Dwi Yuniatri, Nur Khusna yunus, sri ulan dari