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All Journal Competitor : Jurnal Pendidikan Kepelatihan Olahraga JOURNAL SPORT AREA Riyadhoh : Jurnal Pendidikan Olahraga Journal of Applied Science, Engineering, Technology, and Education Nanggroe: Journal Of Scholarly Service Seminar Nasional Hasil Penelitian LP2M UNM Ininnawa: Jurnal Pengabdian Masyarakat Nanggroe: Journal of Scholarly Service Journal Of Sport Education, Coaching, And Health Abdi Kimia : Jurnal Pengabdian Masyarakat Jurnal Abdi Negeriku Mammiri: Jurnal Pengabdian Masyarakat Cermin Dunia Kedokteran Jurnal Abdi Bangsa
Hammado, Nurussyariah
Sport And Health Science Faculty, Universitas Negeri Makassar, Department Of Neurology Faculty Of Medicine, Hasanuddin University, Makassar, Indonesia
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The effect of fish oil supplementation on fatigue perception following submaximal exercise during the COVID-19 pandemic Hammado, Nurussyariah; Setyagraha, Etno; Rannu, Fadra Naufal
Journal Sport Area Vol 8 No 1 (2023): April
Publisher : UIR Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25299/sportarea.2023.vol8(1).10187

Abstract

The pandemic of COVID-19 has created the "New Normal" lifestyle and limited people to performing their daily activities from home. These changes in turn affect the level of physical activities, including the intention to engage in regular exercise, in most people, subsequently putting them at risk of having negative effects due to being physically inactive. This condition may down regulate the human immune system, making it more vulnerable to various diseases. Oral supplementation of fish oil has been proposed to have benefits for decreasing pro-inflammatory markers induced by exercise. This study aimed to analyze the effect of fish oil supplementation on the degree of fatigue perception following submaximal exercise. Forty-four male college students participated in this non-equivalent pre-posttest experimental research. The participants were supplemented with 2 soft capsules of 1.5 grams of fish oil for 8 weeks. The effect of submaximal exercise was carried out by the sit-up and bleep tests, which were measured before and after 8 weeks of fish oil supplementation. The research procedure was approved by the ethics committee of the Makassar State University research institute. The results showed that there was a strong relationship between the administration of fish oil supplements and the level of fatigue perception following sit-ups and bleep tests (p values of -0.529 and -0.658, respectively) performed during the COVID-19 pandemic. This study concludes that the administration of fish oil supplementation affects the degree of fatigue perception after doing submaximal exercise, especially during the COVID-19 pandemic.
AREDS2 sebagai Strategi Perlindungan Retina Terhadap Penuaan: Tinjauan Pustaka dari Perspektif Gerosains: Tinjauan Pustaka Wilaksono, Bhirau; Elfandari, Enno; Ichsan, Rayhani; Alfiandari, Dhini; Damry, Nurul Muf'idah; Chairul, Andi Makkawaru; Aminuddin, Nurul Mutiah; Nurdin, Novi Safitri; Chandrawati, Aida Ayu; Hammado, Nurussyariah
Cermin Dunia Kedokteran Vol 53 No 08 (2026): Agustus 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i08.2130

Abstract

Introduction: Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss among the elderly population. The Age-Related Eye Disease Study 2 (AREDS2) supplementation was developed as an evidence-based nutraceutical strategy to slow the progression of AMD. This review aims to evaluate the clinical evidence and potential application of AREDS2 as a geroprotective retinal intervention within the framework of precision geromedicine. Methods: A narrative review of recent AREDS and AREDS2 studies was conducted, integrating concepts from geroscience related to retinal aging. Results: The AREDS2 formulation, which replaced beta-carotene with lutein and zeaxanthin, demonstrated an 18% reduction in AMD progression risk without increasing lung cancer risk among smokers. AREDS2 components target key aging pathways, including oxidative stress, mitochondrial dysfunction, chronic inflammation, and dysregulated autophagy. In addition, potential modulation of mTOR and AMPK signaling suggests a role in extending retinal healthspan. Conclusion: AREDS2 represents a promising nutraceutical approach as a retinal gerotherapy within the paradigm of precision geromedicine. Its clinical implications include preventing AMD progression, optimizing visual function in older adults, and enabling integration into precision-based ophthalmologic practice. Further research is warranted to validate the molecular mechanisms and assess the cross-population effectiveness, thereby strengthening its role in broader age-related ocular health interventions.
Co-Authors A. Febi Irawati Alfiandari, Dhini Amran, Muhammad Yunus Bahar, Ashari Bhirau Wilaksono Bismar, Ahmad Rum Chairul, Andi Makkawaru Chandrawati, Aida Ayu Damry, Nurul Muf'idah Elfandari, Enno Fitrisyah, Andi Mega Gafur, Rahmi Guruh Amir Putra Haikm, Hikmad Hammado, Nururrahmah Hanifah, Yusfiah Husnul Herman H, Herman Ichsania, Nurul IRFAN IDRIS Jamaluddin Jamaluddin Kasmad, Rahmat M. Rachmat Kasmad Meryana*, A. Kurnia Bintang**, Muh. Akbar**, Susi Aulina**, Yudy Goysal**, Arifin Limoa*** Mujahidah Yunus Nurdin, Novi Safitri Nurul Athirawanty Afany Nurul Musfira Amahoru Nurul Mutiah Aminuddin Paramita, Diah Astini Putra, Guruh Rahman, Zaina RAMDHANI RAMDHANI Rannu, Fadra Naufal Rasna, Rasna Ratnawati Ratnawati Rayhani Ichsan Ristiana, Evi SAHABUDDIN SAHABUDDIN Saputra, Ricky Sarea, Syahrianti Setyagraha, Etno Sudiadharma, Sudidharma Wilaksono, Bhirau Wuysang, Audry Devisanty Yade Kurnia Yasin, Yade Kurnia Yasin, Yade K Yusminah Hala Yusnaeni Yusuf