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All Journal Jurnal Eksplora Informatika Jurnal Sisfokom (Sistem Informasi dan Komputer) Indonesian Journal of Global Health research Journal of Pharmaceutical and Health Research Cermin Dunia Kedokteran Sewagati Jurnal Penyakit Dalam Indonesia Svāsthya: Trends in General Medicine and Public Health Journal of Medicine and Health Technology Cermin Dunia Kedokteran
Dwinka Syafira Eljatin
Faculty Of Medicine And Health, Institut Teknologi Sepuluh Nopember
Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Ankle Joint Chronic Osteomyelitis: A Case Report and Updated Insights Tika, Fanny Eprilia; Muhammad, Ismail; Eljatin, Dwinka Syafira; Adnyana, I Made Dwi Mertha
Indonesian Journal of Global Health Research Vol 6 No 2 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i2.2902

Abstract

Osteomyelitis is an infectious disease of the musculoskeletal system that can cause inflammation of the bones and joints caused by infectious agents. To date, there has been an increase in Osteomyelitis cases especially in individuals with comorbidities. The aimed of this study was to explore the frequent cases of chronic ankle joint osteomyelitis experienced by the public and provide new insights into the future treatment of this disease. In this study, we report the case of a patient with type 2 diabetes mellitus who developed osteomyelitis due to a wound caused by a scratch on a prickly pandanus leaf mat. A 58-year-old man presented to the emergency room with complaints of sores and pain, accompanied by swelling of the right foot. The wound on the leg oozed pus had an odor, and the patient had difficulty walking and fever for two weeks. Her hemoglobin level was 10 mg/dl, her leukocyte count was 20,040/µL, her current blood sugar level was 323 mg/dL, her 2-hour PP blood sugar level was 415 mg/dL, and her HbA1c level was 12. On foot examination, a CRT of < 2 s was found, and the degree of dorsal pedic artery pulsation was weak. An opaque area was observed in the ankle joint of the right foot, accompanied by a distal 1/3 epi-metaphyseal fracture of the right fibula bone with swelling, a distal 1/3 epiphyseal deformity of the right tibia bone, and a calcaneal spur on X-ray. Trauma and systemic risk factors such as diabetes mellitus were found in the patient, increasing the risk of worsening chronic osteomyelitis. The principles of osteomyelitis management include optimizing the patient's general condition; performing pharmacological debridement, reconstruction, and stabilization; and completing rehabilitation. Recent insights highlight the importance of a multidisciplinary approach, advanced diagnostic tools, antibiotic stewardship, novel therapies, and patient-centered care to improve outcomes for individuals affected by this challenging condition in the future.
Improving the Knowledge and Attitudes of Pulmonary Tuberculosis Prevention in the Probolinggo Community with Counseling and the Use Of Sobat-TB Haykal, Muhammad Nazhif; Eljatin, Dwinka Syafira; Putri, Atina Irani Wira; Karimah, Rumman; Fitriani, Fatimah Nur; Putra, Gumilar Fardhani Ami; Hidayah, Rizka Nurul; Fadhlina, Afia Nuzila; Fatmasari, Hindana; Widodo, Aulia Febrianti; Sakina, Sakina
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.3480

Abstract

Tuberculosis (TB) is a significant global health issue, particularly in Indonesia. The increasing number of TB cases and deaths highlights the need for health education to reduce the incidence of TB and support eradication efforts. Objective: This study aimed to analyze the knowledge and attitudes of the Probolinggo community toward preventing pulmonary TB through counseling and the use of the Sobat-TB. Method: An analytical observational study with a cross-sectional approach was conducted. The knowledge and attitudes of 50 voluntary respondents were measured using a validated and reliable questionnaire before and after health education interventions, which included counseling, educational videos, and an introduction to the Sobat TB app. The data were analyzed descriptively and statistically at the 95% confidence level. Results: In the Puskesmas Kanigaran area, the initial findings showed poor knowledge and attitudes toward TB prevention among respondents. Postintervention, there was a significant improvement: 46 out of 50 respondents had good knowledge, and 48 out of 50 had positive attitudes toward TB prevention. Statistical analysis confirmed a significant relationship between pre- and postintervention knowledge and attitudes (p=0.0001). Conclusions: Enhanced access to information and continuous health education using modern technology are crucial for achieving TB elimination goals.
Evaluation of The Poedji Rochjati Score Card (PRSC) on Digital Platform @hamilku.id Based on The Delphi Method Fadli, Sonny; Wibawa, Adhi Dharma; Eljatin, Dwinka Syafira
Eksplora Informatika Vol 14 No 1 (2024): Jurnal Eksplora Informatika
Publisher : Institut Teknologi dan Bisnis STIKOM Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30864/eksplora.v14i1.1108

Abstract

The number of cases and deaths of mothers and babies in Indonesia is increasing, which is mediated by low-risk detection in early pregnancy, and a lack of knowledge resulting in the dissemination of pregnancy-related information tends to be poorly understood. As a solution to this problem, the purpose of this study was to analyze the effectiveness and usability of the Poedji Rochjati Score Card (PRSC) feature on the @hamilku.id Digital Platform based on the Delphi method. Qualitative research methods with technical observations were carried out online by obstetricians and gynecologists. The main focus of this research was usability testing involving 46 pregnant women who used the application and 9 randomly selected respondents. The assessment and evaluation were guided by the Delphi method, which involved two rounds of testing by six obstetricians and gynecologists. The results were descriptively analyzed. The findings showed that pregnant female respondents aged between 17 and 34 years had a higher education level, were dominated by people without jobs/housewives, were domiciled in Sidoarjo, had undergone antenatal care (ANC) &le; 6 times, and had undergone &ge; 5 pregnancies. According to the PRS, 52.2% of pregnant women were classified as having high-risk pregnancies (HRPs). Based on the evaluation of the application from the usability aspect, 83.3% of the participants stated that the information was comprehensive and that the medical terminology was easy to understand. However, only half of them considered visualization in the form of images or animations to be very helpful in illustrating pregnancy risks. Delphi testing with obstetricians and gynecologists revealed that the digital PRSC features generated positive ratings, indicating that the tool is accurate, informative, easy to understand, and effective at improving the quality of health services. The second round showed an improvement in the quality and relevance of the digital PRSC features, with more diverse feedback from the respondents providing a broader perspective for future research and feature development. As a result, the digital PRSC feature can help individuals precisely and accurately identify pregnancy risks.
Successful Management of High-Risk Pregnancy with TORCH Infection History and Chronic Hypertension Karimah, Rumman; Fadli, Sonny; Eljatin, Dwinka Syafira; Indriastuti, Endah; Sari, Desiana Widityaning; Ridhoi, Ahmad
Journal of Medicine and Health Technology Vol. 1 No. 2 (2024)
Publisher : Direktorat Riset dan Pengabdian Kepada Masyarakat, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j30466865.v1i2.1129

Abstract

A 41-year-old pregnant woman of Javanese ethnicity attended the outpatient clinic of a private hospital, presented with fifth pregnancy and no living children due to a history of ectopic pregnancy, two times IUFD, and one time neonatal death. The patient also had a history of chronic hypertension and asthma. The examination showed positive IgG Toxoplasma and CMV antibody levels. The patient's blood pressure also never touched the normal limit since the beginning of pregnancy. At the end of pregnancy, she had very high blood pressure and proteinuria. According to WHO Maternal Mortality Rate (MMR) is still very high, where two of the five highest causes are infection and hypertension in pregnancy. High risk pregnancies require special attention in monitoring during pregnancy and management. In a history of bad obstetrical history it is necessary to screen for infection which can be done by antibody serology testing. A positive IgG indicates immunity to the virus, if possible it is necessary to check IgG Avidity to determine whether therapy is still needed or can rely on the immune system that has been formed. Chronic hypertension (Systolic Blood Pressure (SBP) > 140 mmHg and / or Diastolic Blood Pressure (DBP) > 90 mmHg since < 20 Weeks Gestational Age (WGA) until 42 days after delivery). First-line Labetalol and Nifedipine or second-line Methyldopa and Hydrochlorothiazide should be considered depending on the condition and gestational age. If there are signs of preeclampsia, termination should be done if possible, along with antihypertensives and anticonvulsants such as MgSO4.
CRISPR-Cas9 Genome Editing Technology for Zoonotic Disease Control in Indonesia: A Comprehensive Review Adnyana, I Made Dwi Mertha; Eljatin, Dwinka Syafira; Sudaryati, Ni Luh Gede; Adiwinoto, Ronald Pratama; Raza, Syed Meesam; da Cruz , Zito Viegas
Journal of Medicine and Health Technology Vol. 1 No. 1 (2024)
Publisher : Direktorat Riset dan Pengabdian Kepada Masyarakat, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j30466865.v1i1.1172

Abstract

The increasing emergence of zoonotic diseases originating from vectors, rodents, mammals, and others has increased the potential for outbreaks of pandemics in the Indonesian territory. Although control and prevention have been implemented, these efforts have not yet revealed a bright spot; therefore, elaboration with advanced CRISPR-Cas9 technology is a way to accelerate efforts to control zoonotic diseases in Indonesia. However, there is limited literature on this topic. This review aims to comprehensively describe, identify, and summarize the application of CRISPR-Cas9 genome-editing technology in zoonotic disease control in Indonesia. Our findings show that CRISPR-Cas9 genome editing technology offers an innovative approach for zoonotic disease control by targeting disease vectors, modifying animal reservoirs, improving disease surveillance, enhancing vaccine development, and exploring traditional medicine candidates and immunotherapy. The high level of precision, efficiency, and versatility in targeting genomes capable of disrupting, damaging, and disrupting the disease transmission cycle in pathogens makes CRISPR-Cas9 highly effective. However, challenges such as off-target impacts, regulatory complexity, and ethical considerations must be overcome with inter- and multidisciplinary collaboration to promote transparency, equity, and public engagement throughout the process of implementing this technology in the field, especially in Indonesia.
Mpox, HIV infection, and genital skin disease: triple burden, threats and challenges from an epidemiological perspective Adnyana, I Made Dwi Mertha; Eljatin, Dwinka Syafira; Maulana, Sidik; Ibrahim, Kusman; Umar, Tungki Pratama; Armini, Luh Nik; Cruz, Zito Viegas da
Svāsthya: Trends in General Medicine and Public Health Vol. 1 No. 1 (2024): July 2024
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v1i1.1

Abstract

The expansion and transformation of Mpox (MPX) disease alongside HIV and genital skin diseases has led to an increase in global morbidity and mortality in a relatively brief period. These diseases have a similar transmission pathway through sexual intercourse (mainly MSM/men-sex with males). This review aims to provide a concise, evidence-based overview of MPX, HIV, and genital skin disease coinfections, and to identify epidemiological threats and challenges. Our investigations revealed that from January 2022 to July 2023, there was a significant increase in the number of MPX cases, which reached a total of 88,600, resulting in 152 deaths across 113 countries. There have been case reports of triple-burden disease in six different areas of the world, with at least 52% of reported cases occurring in men who have had sexual activity with other men, 84.1% of whom do not use condoms and do not take pre-exposure prophylaxis (PrEP). In addition, the highest number of deaths due to co-infection with MPX, HIV infection, and genital skin diseases occurred in vulnerable groups (LGBTQIA2S+), especially in men who had sex with men, up to 90.9%, and experienced an increase in the frequency of triple burden diseases to 104.9%. From an epidemiological standpoint, this condition generates several threats and challenges, including an increasing burden of infectious diseases, an increase in immunocompromised populations, an increase in overlapping risk factors, diagnostic difficulties, an increase in interactions and comorbidities, and relatively complex treatment challenges. To suppress these outbreaks and pandemics, comprehensive control and prevention should be proposed collaboratively, including collaboration with the education sector to conduct better research and investigation using one health in complex settings. Epidemiological modeling can be used in the future to accelerate the control of these diseases.
Co-Authors -, Awalita Abdurahman Abdurrahman Adhi Dharma Wibawa, Adhi Dharma Adnyana , I Made Dwi Mertha Awalita Awalita - Cruz, Zito Viegas da da Cruz , Zito Viegas Djaputra, Edith Maria Fadhlina, Afia Nuzila Fadli, Sonny Fatmasari, Hindana Fitriani, Fatimah Nur Gaby Demitria Agustina Sianturi Galenisa Falinda Santika Haque, Sayidah Aulia Ul Haykal, Muhammad Nazhif Haykal, Muhammad. Najib Hedianto, Tri Hidayah, Rizka Nurul Hutagalung, Muhammad Bayu Zohari Imam Susilo Indriani, Ratri Dwi Indriastuti, Endah Indriastuti, Endah Ismail Muhammad Karimah, Rumman Kusman Ibrahim Luh Nik Armini Mahdi, Faizal Maulana, Sidik Muhamad Frendy Setyawan Muhammad Bayu Zohari Hutagalung Muhammad Bayu Zohari Hutagalung Muhammad Ridho Akbar Eljatin Ni Luh Gede Sudaryati Njoto, Edwin Nugroho Parlindungan, Putra Gelar Putra, Gumilar Fardhani Ami Putri Alief Siswanto Putri, Atina I.W. Putri, Atina Irani Wira Radiansyah, Riva Satya Rangkuti, Rahmah Yasinta Raza, Syed Meesam Ridhoi, Ahmad Ronald Pratama Adiwinoto Sakina Sakina Sakina, Sakina Santika, Galenisa Falinda Sari, Desiana Widityaning Sarie, Vivi Permana Sianturi, Gaby Demitria Agustina Syulthoni, Zain Budi Tika, Fanny Eprilia Umar, Tungki Pratama Vivi Permana Sarie Widodo, Aulia Febrianti Yuri Pamungkas