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All Journal Dentika Dental Journal Jurnal Kesehatan Andalas Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Jurnal Biomedika dan Kesehatan Jurnal Keperawatan dan Fisioterapi (JKF) Jurnal Kesmas dan Gizi (JKG) IJOEP : International Journal of Ecophysiology SCRIPTA SCORE Scientific Medical Journal The International Journal of Tropical Veterinary and Biomedical Research
Widjaja, Sry Suryani
Department Of Biochemistry, Faculty Of Medical, Universitas Sumatera Utara, Medan, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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DNMT1 Level as Biomarker for Early Detection of Nasopharyngeal Carcinoma Raudah Putri Syari; Zulham Yamamoto; Farhat; Sry Suryani Widjaja; Ririe Fachrina Malisie
JURNAL KEPERAWATAN DAN FISIOTERAPI (JKF) Vol. 8 No. 1 (2025): Jurnal Keperawatan dan Fisioterapi (JKF)
Publisher : Fakultas Keperawatan dan Fisioterapi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/qwakjv41

Abstract

Introduction: Nasopharyngeal carcinoma (NPC) is a malignant disease often diagnosed at an advanced stage. Early detection of NPC is necessary to reduce morbidity and mortality of this disease. To date, early detection methods for NPC still have limitations, especially in terms of positive predictive value. Identification of DNA methylation abnormalities has been studied for its role as a marker for early detection of NPC. Objective: This review describes the potential of DNMT1, an enzyme involved in DNA methylation, as a biomarker for early detection of NPC. Methods: We conducted a literature search using PubMed and Google Scholar databases. The keywords used were "nasopharyngeal carcinoma AND DNMT1", nasopharyngeal carcinoma AND early detection, "nasopharyngeal carcinoma AND screening", nasopharyngeal carcinoma OR DNMT1, “DNMT1 OR Carcinoma”, nasopharyngeal carcinoma OR screening, and nasopharyngeal carcinoma OR early detection. Results: Increased DNMT1 expression is associated with global hypermethylation which is part of the early pathogenesis of NPC. LMP1, as an oncoprotein released by EBV, increases DNMT1 expression and activity. Conclusion: High DNMT1 expression in NPC indicates its potential as an early detection method for NPC.
The Tooth Agenesis in Clinical Practice: A review of Case Reports Michael Dany; Ameta Primasari; Ervina Sofyanti; Sry Suryani Widjaja; Thantrira Porntaveetus
Dentika: Dental Journal Vol. 28 No. 1 (2025): Dentika: Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/dentika.v28i1.20149

Abstract

Tooth agenesis (TA) relates to multiple congenital dental disorder and the most prevalent developmental disorders affecting approximately 200 million people globally. The management of TA require interdisciplinary dental approaches. Therefore, this study aimed to conduct a case report evaluation of TA based on population and ethnicity. This scoping reviews based on  Preferred Reporting Items for Systematic Reviews and Meta-Analyses, has been registered in Open Science Framework. Relevant articles were retrieved from Proquest, Science Direct, PubMed, and SpringerLink databases with keywords comprising of ‘Prevalence’ AND ‘Tooth Agenesis’ AND ‘Nonsyndromic or Syndromic’. From 2014 to 2024, there were only five non-syndromic tooth agenesis case reports were included to be reviewed. The review of multiple case reports of tooth agenesis demonstrated significant variability in clinical and radiography evaluation involving inheritance pattern. By early identification in mixed dentition, the comprehensive and individualized treatment approaches are required to address both esthetics and functional outcomes. Further population-based studies of genetic involvement in TA can contribute early detection of malocclusion.   
Effects of Curcuma longa L. on antibody titer and body weight of sheep post vaccination for house and mouth diseases Hasibuan, Anggiriani Mutiara Sari; Widjaja, Sry Suryani; Lubis, Inke Nadia D.
The International Journal of Tropical Veterinary and Biomedical Research Vol 9, No 1 (2024): Vol. 9 (1) May 2024
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/ijtvbr.v9i1.36535

Abstract

Foot and mouth disease (FMD) is an acute and highly contagious viral infectious disease in even/split-hoofed animals and some wild animals. Diseases of the mouth and hoof can cause significant economic losses due to declining production and become an obstacle to the trade in animals and their products. FMD causes much harm to infected animals, one of which is weight loss. Vaccination is the most critical factor in the control of FMD, and the type and quality of vaccines available play an essential role. However, immunomodulators are also needed to increase the immune response to the current FMD vaccine. It is reported that administering Curcuma longa to experimental animals could increase body weight gain and immunity by increasing antibody titers. Therefore, this article will review the immunomodulatory properties of Curcuma longa about FMD infection.
Co-Authors AA, Rizka Aldy Safruddin Rambe Ameta Primasari C, Teguh Denny Rifsal Siregar Dina Arwina Dalimunthe, Dina Arwina EM, Samuel Ervina Sofyanti Farhat Harahap, Desy Aryani Hasibuan, Anggiriani Mutiara Sari Lubis, Inke Nadia D. Lubis, Nenni Dwi Aprianti M. PANDAPOTAN NASUTION Maya Savira Mayasari, Evita Melya Susanti Michael Dany Muhammad Ichwan Nova Eininta Sitepu Paramita, Deryne Anggia Raudah Putri Syari RICA VERA BR TARIGAN Rifqi Hamdani Pasaribu Rina Amelia Ririe F. Malisie Ririe Fachrina Malisie rusdiana Rusdiana Rusdiana Rusmalawaty, Rusmalawaty Samosir, Fauzan Azmi Hasti Habibi Simamora, Rizka Amini Sriwulan, Anyelin Sulviani, Nurul Thantrira Porntaveetus W, Steven Y, Devi Yamamoto, Zulham Yudhistira, Ashri