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All Journal Pharmascience Acta Pharmaciae Indonesia : Acta Pharm Indo Jurnal Biologi Tropis Journal of Fundamental and Applied Pharmaceutical Science Jurnal IPTEK Bagi Masyarakat Jurnal Ilmiah Bakti Farmasi Journal of Biotechnology and Natural Science Jurnal Ilmiah Kesehatan Delima Parapemikir Jurnal Ilmiah Farmasi Jurnal Medika: Medika Jurnal Farmasi Galenika
Kholifah, Eva
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Peran Apoteker dalam Kepatuhan Penggunaan Tablet Tambah Darah untuk Pencegahan Stunting pada Siswi Pelita Cibitung Yusransyah, Yusransyah; Alfarizqi, Asep Salman; Sudarto, Teguh; Kholifah, Eva; Stiani, Sofi Nurmay; Udin, Baha
Jurnal IPTEK Bagi Masyarakat Vol 4 No 3 (2025)
Publisher : Ali Institute of Research and Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55537/j-ibm.v4i3.1114

Abstract

Anemia in adolescent girls is a significant health issue in Indonesia, with high prevalence and long-term impacts on reproductive health, as well as an increased risk of stunting in their offspring. The Iron Supplementation (TTD) program has been initiated by the government as a stunting prevention effort, yet adherence to TTD consumption among adolescent girls remains low. The role of pharmacists as educators and facilitators in public health programs is crucial in improving TTD consumption adherence. This community service aims to improve adherence to TTD consumption as a stunting prevention measure among female vocational school students through the Anti-Stunting Movement Program at Pelita Cibitung Vocational School in 2024. Activities conducted include interactive education on stunting, anemia, and the importance of TTD consumption, as well as monitoring and evaluating TTD consumption adherence. Evaluation was performed using the Medication Adherence Report Scale (MARS) questionnaire. The evaluation results showed an increase in TTD consumption adherence after education and monitoring through WhatsApp Group. This demonstrates that the active involvement of pharmacists in education and monitoring can improve adherence to TTD consumption in adolescent girls.
PENGARUH EFEK SAMPING OBAT ANTIDIABETES TERHADAP KUALITAS HIDUP PASIEN DIABETES MELLITUS TIPE 2 Insani, Nurul; Nasiah, Nasiah; Kholifah, Eva
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 3 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i3.7130

Abstract

Diabetes melitus merupakan kondisi jangka panjang akibat kerja insulin yang tidak mencukupi atau aktivitas insulin yang tidak adekuat. Penyakit ini berkembang ketika tubuh memproduksi insulin secara berlebihan, sehingga mengganggu fungsi insulin dan menyebabkan sel-sel dalam tubuh menjadi resisten. Penelitian ini bertujuan untuk menganalisis hubungan antar efek samping obat antidiabetes dengan Kualitas Hidup pasien DM. Metode dalam penelitian menggunakan metodologi cross sectional, penelitian observasional dan pengumpulan data kuantitatif. Wawancara langsung dengan responden, kuesioner kualitas hidup dan efek samping digunakan sebagai instrumen dalam pengumpulan data. Subjek penelitian sebanyak 100 pasien DM rawat jalan yang  telah meminum antidiabetik oral serta memenuhi kriteria inklusi dan eksklusi. Hasil penelitian menunjukan dari 100 responden, 17 orang (17,0%) dengan efek samping obat rendah memiliki kualitas hidup yang rendah 12 orang atau (12,0%), sedang 24 (24,0%) dan dengan kualitas hidup tinggi tidak ada. 41 orang (41,0%) dengan efek samping obat sedang memiliki kualitas hidup rendah 24 (24,0%), sedang 17 (17,0%) dan tinggi tidak ada. Sedangkan efek samping yang tinggi sebanyak 42 ( 42,0 %) dengan kualitas hidup rendah sebanyak 15 (15,0%), sedang 27 (27,0%) dan dengan kualitas hidup tinggi tidak ada. Penelitian ini menunjukkan bahwa efek samping yang dialami penderita DM baik ringan, sedang maupun berat sangat signifikan menurunkan kualitas hidup pasien DM.
Uji Antioksidan Kombucha Ekstrak Kunyit dan Seduhan Kunyit Menggunakan Sprektroskopi UV-Vis Nabillah, Deya Adiby; Ismiyati, Renditya; Kholifah, Eva; Endah, Endah; Maulana, Adrian; Asep, Asep
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 3 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i3.8955

Abstract

Radikal bebas yang berasal dari udara, makanan dapat menyebabkan gangguan kesehatan tetapi dapat ditangkal dengan antioksidan. Antioksidan dapat diperoleh dari tanaman dan salah satunya ialah kunyit. Tujuan penelitian ini untuk mengetahui kekuatan aktivitas antioksidan dari ekstrak kunyit. Penelitian dilakukan dengan cara ekstraksi serbuk kunyit yang telah diterminasi dengan metode maserasi menggunakan pelarut etanol serta seduhan, kemudian masing-masing larutan difermentasi menjadi kombucha. Kombucha ekstrak kunyit dan seduhan kunyit dilakukan penapisan fitokimia, selanjutnya dilakukan pengujian aktivitas antioksidan menggunakan metode DPPH serta vitamin C sebagai kontrol positif. Hasil penelitian ini diharapkan mendapatkan kombucha ekstrak kunyit dan seduhan kunyit yang memiliki aktivitas sebagai antioksidan. Berdasarkan hasil penelitian dapat disimpulkan bahwa aktivitas antioksidan dari kombucha ekstrak kunyit dan kombucha kunyit memberikan pengaruh terhadap peningkatan aktivitas antioksidan dengan nilai IC50 masing-masing yang dihasilkan sebesar 46,6 ppm dan 5,25 ppm termasuk dalam kategori antioksidan sangat kuat.
Antibacterial Activity of Jotang Flower Infusion (Acmella paniculata) against Staphylococcus aureus Skania, Pratiwi Cahya; Kholifah, Eva; Agustin, Siti
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7877

Abstract

Among its various uses, the plant Jotang (Acmella paniculata), which is a member of the Asteraceae family, possesses antibacterial and anti-infective properties in its floral section. The majority of diseases are caused by the Streptococcus aureus bacteria. The purpose of this study was to evaluate the antibacterial activity of jotang flower infusion against Streptococcus mutans at doses of 75%, 50%, and 25%. The antibacterial activity was evaluated using the agar diffusion method, with chloramphenicol acting as a positive control. At 25%, 50%, and 75% dosages, the average inhibition zone diameter in the jotang inhibition test was 5.00 mm, 6.00 mm, and 6.06 mm, respectively. Chloramphenicol, the positive control, had a measurement of 9.96 mm. According to the study's results, jotang flower infusion has a somewhat effective antibacterial effect on Streptococcus aureus.
Computational Study of N-Hexane Extract of Jotang Herba (Acmella uliginosa) Nabillah, Deya Adiby; Kholifah, Eva; Ahmaddhani, Surya
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8268

Abstract

The study investigates the in silico toxicity of n-hexane extract from Acmella uliginosa (Jotang) herb, a plant widely used in traditional medicine. In silico methods, such as molecular docking, toxicity prediction, and ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis, were employed to assess the potential harmful effects of the extract’s chemical constituents. The primary aim was to evaluate the safety profile of the extract in terms of cytotoxicity, mutagenicity, and organ toxicity. The study used computational tools like Pre.ADMET to predict various toxicological endpoints based on the molecular properties of the compounds identified in the n-hexane extract. The results suggested that while some compounds exhibited low toxicity risk, others showed potential mutagenic or hepatotoxic effects. This in silico approach provides a rapid and cost-effective method for preliminary toxicity assessment, offering valuable insights for further in vivo or clinical studies. The findings underscore the importance of integrating computational techniques into the safety evaluation of herbal medicines.
Pengaruh Edukasi Terhadap Tingkat Pengetahuan Pengobatan Medis Pada Santri Pondok Pesantren Al-Hikmat Dan Nurul Hikmat Pandeglang Banten Yusransyah, Yusransyah; Lukmanul Hakim, Imam; Kholifah, Eva
JURNAL FARMASI GALENIKA Vol 9 No 2 (2022): Jurnal Farmasi Galenika Vol 9 No 2
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v9i2.219

Abstract

Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan santri pondok pesantren Al-Hikmat dan Nurul Hikmat tentang pengobatan medis sebelum dan setelah diberikan edukasi, serta mengetahui adanya pengaruh pemberian edukasi terhadap tingkat pengetahuan pengobatan medis pada santri pondok pesantren Al-Hikmat dan Nurul Hikmat. Manfaat penelitian ini dapat memberikan gambaran melalui data penelitian yang diperoleh tentang pengaruh pemberian edukasi terhadap peningkatan pengetahuan pengobatan medis pada santri pondok pesantren Al-Hikmat dan Nurul Hikmat. Penelitian ini diharapkan mampu meningkatkan pengetahuan santri pondok pesantren Al-Hikmat dan Nurul Hikmat dalam pengobatan medis. Metode penelitian Pre-Experimental Designs dengan teknik pengumpulan data pretest dan posttest pada santri di pondok pesantren Al-Hikmat dan Nurul Hikmat. Data hasil penelitian di analisis menggunakan program SPSS (kolmogorov-smirnov two sample test dan paired samples t-test). Hasil penelitian menunjukan bahwa tingkat pengetahuan santri bertambah setelah diberikan edukasi. Hal ini dibuktikan dengan hasil uji statistik t-test berpasangan, yang diperoleh nilai p= 0,000 yang mana nilai tersebut kurang dari 0,05.
PENGARUH EDUKASI TERHADAP PENGETAHUAN DAN SIKAP ORANG TUA PADA KASUS SEDIAAN SIRUP OBAT PENURUN DEMAM DI DUA DESA KABUPATEN TANGERANG Insani, Nurul; Aziya, Hasna; R, Asti Yunia; Kholifah, Eva
Parapemikir : Jurnal Ilmiah Farmasi Vol 13, No 2 (2024): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v13i2.6949

Abstract

Education is an educator's effort to convey knowledge or messages to communities, groups or individuals, from not knowing to knowing. Ethylene glycol and Diethylene glycol are alcohols that have toxic properties that can increase mortality and morbidity when their use exceeds the provisions or limits that have been set. This study aims to determine the level of knowledge and attitudes of parents in Kronjo Village and Bakung Village about the case of fever-reducing syrup preparations as the main factor causing atypical progressive acute renal failure in children after being given education. Cross sectional research design with pretest and posttest data collection techniques on parents in Kronjo Village and Bakung Village. The data were then analyzed using an application called SPSS (Kolmogorov-smirnov two sample test and Wilcoxon Sign Rank Test). The results showed that the level of knowledge and attitude of parents in Kronjo Village and Bakung Village had increased after being given education. This is evidenced by the results of data that has been analyzed using the Wilcoxon Sign Rank Test with a p value of 0.000 ≤ 0.05, which means there is a significant difference.  
Tingkat Pengetahuan Karang Taruna Cahaya Mandala dalam Pembuatan Kombucha Bunga Kecombrang di Desa Mandalawangi Kholifah, Eva; Nabillah, Deya Adiby; Suhaemi, Muhamad; Endah, Endah; Ismiyati, Renditya; Anton, Anton; Asep, Asep; Maulana, Balqis; Ahmaddhani, Surya; Nabilah, Syala
Jurnal Medika: Medika Vol. 4 No. 4 (2025)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/gena5b10

Abstract

This community service activity was motivated by the potential of local natural resources in the form of Torch Ginger flowers (Etlingera elatior) in Mandalawangi Village, Pandeglang Regency, which have not been optimally utilized despite their high antioxidant activity and potential to be processed into probiotic kombucha beverages that are beneficial for health and possess economic value. The purpose of this activity was to improve the knowledge and skills of members of the Karang Taruna Cahaya Mandala in producing Torch Ginger flower kombucha as an effort to enhance public health and welfare. The activity was carried out through interactive lectures, hands-on training, and counseling using leaflet media, involving 30 respondents selected based on their active participation in the community. Knowledge evaluation was conducted through pretest and posttest assessments using the Wilcoxon test to analyze significant differences in knowledge levels before and after the activity. The results showed an increase in the knowledge level categorized as “good” from 63% before the training to 90% after the training, with a significance value of p = 0.000 (p<0.05), indicating that the activity was effective in improving participants’ understanding of Torch Gingerflower kombucha production. In addition to increasing health awareness, this activity also contributed positively to community economic empowerment through the development of local value-added products. In conclusion, the training and counseling on Torch Ginger flower kombucha production proved effective in enhancing community knowledge and skills; however, further activities are recommended, including business mentoring and product certification, to ensure the sustainability and broader impact of the program.
Co-Authors Agustian, Lolo Agustin, Siti Ahmaddhani, Surya Alfarizqi, Asep Salman Alfiyah, Siti Alifia A.T, Mohammad Anton Anton Arifah, Mitsalina Fildzah Asep Aziya, Hasna Baha Udin Cahya Skania, Pratiwi endah, endah Fajrin Noviyanto, Fajrin Fitriani, Via Ismiyati, Renditya Kurnia, Nia Marlina Kurniasih, Kholif Sholehah Indra Lukmanul Hakim, Imam Maulana, Adrian Maulana, Balqis Nabilah, Syala Nabillah, Deya Adiby Nasiah Nasiah, Nasiah Nur Insani Nur S, Afifah Perdana Priya Haresmita, Perdana Priya Puspita Septie Dianita, Puspita Septie R, Asti Yunia Rahmah, Syafira Atika Saputra, Ilham Fahmi Setiyawati, Eka Ayu Shobah, Afifah Nur Stiani, Sofi Nurmay Sudarto, Teguh Suhaemi, Muhamad Widianingrum, Lucia Yusransyah, Yusransyah Zahroh, Siti Lailatu