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All Journal Alchemy : Journal of Chemistry Jurnal Surya Medika Jurnal Analis Kesehatan Jurnal Biomedika Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Jurnal Peduli Masyarakat Indonesian Journal of Global Health research Jurnal Farmasi LOSARI: Jurnal Pengabdian Kepada Masyarakat Journal of Nursing and Health (JNH) Akper Yakpermas Banyumas An Idea Health Journal Jurnal Kesehatan Kusuma Husada Jurnal Farmasetis Journal of Environment and Sustainability Education GEMASSIKA: Jurnal Pengabdian kepada Masyarakat Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Wimpy, W
Sekolah Tinggi Ilmu Kesehatan Nasional
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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Evaluation of Blood Mercury Levels and Creatinin Levels in Indonesian Traditional Gold Miners in Central Java Wimpy, Wimpy; Widhiyastuti, Endang; Puspitasari, Lala
Indonesian Journal of Global Health Research Vol 6 No 4 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i4.3519

Abstract

Based on the world gold council data in 2024, Indonesia is the eighth largest gold producing country in the world. More than 200 gold mining locations spread throughout Indonesia, but gold mining processes in Indonesia especially in Central Java are still carried out traditionally. The importance of this research is that traditional gold mining can lead to health issues such as mercury poisoning and impaired kidney function wich is characterized by the increased of creatinine levels Purpose : to evaluate the blood mercury levels and creatinine levels in Indonesian traditional gold miners in Central Java. Methods : This research uses a cross-sectional analitycal method. The number of samples in this research was 20 gold miners as respondents using a quota sampling technique. Data on blood mercury level results were obtained by examining blood mercury levels with a mercury analyzer and creatinine levels were obtained by examining serum creatinine with a photometer. The spearman’s rho test is used to test the correlation between blood mercury and creatinine levels. Results : As many as 19 out of 20 respondents had mercury levels of more than 20 µg/L, exceeding the threshold set by NCBI but they all had creatinine levels that were still within normal limits according to the NCBI limits wich is less than 1,2 mg/dL. The results of the Pearson correlation test obtained a sig. value (2 tailed) 0,962 where it can be concluded that there is no correlation between blood mercury levels and creatinine levels in.
Pemberdayaan Masyarakat Melalui Edukasi dan Pemeriksaan Payudara Sendiri (SADARI) sebagai Upaya Pencegahan Dini Kanker Payudara di Desa Bentakan, Baki, Sukoharjo Wimpy; Endang Widhiyastuti; Astri Aditya Wardhani; Yusuf Gesha Kesumawijaya; Nathania Thea Vashty Dwi Andiny; Nur Fadilah; Dewi Kumalasari; Vindy Widya Kusumaning Tyas
LOSARI: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 2 (2026): Agustus 2026
Publisher : LOSARI DIGITAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53860/losari.v8i2.580

Abstract

Breast cancer has the highest incidence among women in Indonesia and remains a leading cause of cancer-related mortality, especially in rural areas with limited health education and low awareness of early detection. This community service program aimed to improve knowledge and skills of Breast Self-Examination (BSE) in Bentakan Village, Sukoharjo. The program involved 26 women of reproductive age and health cadres through education, interactive discussion, and hands-on practice using breast models. Evaluation was conducted using pre-test and post-test with knowledge categorization and paired sample t-test analysis. The results showed a shift in knowledge distribution, where poor knowledge decreased from 61.5% to 0% and good knowledge increased from 0% to 69.2%. Paired sample t-test analysis confirmed a significant increase in knowledge (p < 0.001). This program effectively improved community awareness and skills in early breast cancer detection.
Blood mercury levels and PCR-based GSTP1 and GSTT1 gene profiles in artisanal gold miners: A cross-sectional study Wimpy Wimpy; Yusianti Silviani; Nur Hidayati; Daffina Ramadhani Putri Aribowo; Erni Dwi Septiani; Mohammad Masykuri
Journal of Environment and Sustainability Education Vol. 4 No. 1 (2026)
Publisher : Education and Development Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62672/joease.v4i1.159

Abstract

Mercury (Hg) exposure from artisanal and small-scale gold mining (ASGM) remains a major public health concern, particularly in communities where mercury amalgamation is still widely practiced. Chronic mercury exposure is known to induce oxidative stress and may interfere with detoxification pathways involving glutathione S-transferase enzymes, including GSTP1 and GSTT1. This study aimed to assess blood mercury levels and PCR-based GSTP1 and GSTT1 gene profiles among artisanal gold miners in Central Java. A cross-sectional descriptive study was conducted using whole blood samples from 10 adult males, consisting of 5 artisanal gold miners and 5 non-miner controls. Blood mercury concentrations were measured spectrophotometrically, while GSTP1 and GSTT1 gene profiles were evaluated using polymerase chain reaction (PCR). Blood mercury levels in miners ranged from 20.244 to 67.987 µg/L, exceeding the recommended reference value of <20 µg/L, whereas control subjects showed levels below the threshold. PCR analysis demonstrated expected GSTP1 and GSTT1 bands in all control samples. In contrast, miner samples showed variations in PCR band patterns, including larger than expected amplicons for GSTP1 and absence of GSTT1 amplification in two samples, which may indicate altered gene profiles associated with mercury exposure. In conclusion, artisanal gold miners exhibited elevated blood mercury levels alongside variations in GSTP1 and GSTT1 PCR profiles. Although the small sample size limits definitive genetic interpretation, these findings suggest that combined biomonitoring of mercury burden and detoxification-related gene profiles may provide useful preliminary indicators for assessing susceptibility to mercury exposure in ASGM settings.
Urinary Morphine Detection by Gas Chromatography–Mass Spectrometry for Assessing Methadone Treatment Adherence Wimpy Wimpy; Tantri Daniawaty
An Idea Health Journal Vol 6 No 03 (2026)
Publisher : PT.Mantaya Idea Batara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53690/ihj.v6i03.813

Abstract

Background: Opioid use disorder is a significant public health issue, and adherence to Methadone Maintenance Therapy (MMT) is critical for successful treatment. Self-reported adherence can be biased, so objective laboratory measures are valuable. Urinary morphine detection by Gas Chromatography–Mass Spectrometry (GC-MS) indicates recent illicit opioid use and may signal lower methadone adherence. This study examined the association between GC-MS-confirmed urinary morphine detection and methadone adherence in MMT patients. Methods: This cross-sectional analytical study included 20 MMT patients at the PTRM Clinic of Gambir Public Health Center, selected by quota sampling. Urinary morphine was measured using GC-MS. Treatment adherence was assessed with a modified Morisky Medication Adherence Scale-8 (MMAS-8) and medical records. Data were analyzed using the Fisher–Freeman–Halton Exact Test, with Cramer’s V describing the strength of association. Result: Urinary morphine was detected in 2 participants (10%), while 18 (90%) had results below the detection limit. High, moderate, and low adherence were observed in 65%, 30%, and 5% of participants, respectively. The Fisher–Freeman–Halton Exact Test showed a statistically significant association between urinary morphine detection and methadone adherence categories (p = 0.032). Although Cramer’s V was 0.733, this result should be interpreted with caution due to the small number of positive cases. Conclusion: GC-MS-confirmed urinary morphine detection was significantly associated with lower methadone adherence and may complement behavioral and clinical assessments by providing objective evidence of recent illicit opioid use. These findings are preliminary, and larger multicenter longitudinal studies are needed to confirm their clinical relevance.
Co-Authors Afita Indah Puspitasari. Aminuyati Andika Travel Nasruminalloh Andita, Anung Aprillia Dwi Yanti Ardy Prian Nirwana, Ardy Prian Astri Aditya Wardhani Avicka Clara Yoan Claristya Bayutama, Yudistira Bella Amalia Rizky Wahyudi Cornelia Candra Ayu Prameswari Daffina Ramadhani Putri Aribowo Dewi Kumala Dewi Kumalasari Dewi Saroh Didik Wahyudi Dwi Utami, Hesti Endang Widhiyastuti Enny Listiawati Enny Listiawati Enny Listiawati enny listiawati, enny Erni Dwi Septiani Hendri Hermawan Adinugraha Kadam, Lencana Nurfi’ah Kartika Pertiwi Kusumawardani, Dinda Dwi Lencana Nurfi’ah Kadam Livana PH livana ph Luluk Damayanti Mardiyono Melati Putri Utami Mohammad Masykuri Mulatningtyas, Zevanya Nathania Thea Vashty Dwi Andiny Nur Fadilah Nur Hidayati Nur Hidayati Nurdianto, Sefri Odelia Christiana Utami Oksani, Trifena Wening Oktaviana Puteri Megawati Paramita, Adelia Putri Pramuditha, Zevanya Mulatningtyas Purwati Purwati Puspitasari, Lala Putri, Nonik Restu Putrie Prameswari Ratna Sari Reraska Reraska Reynandar Wilda Muhammad Rhomadona, Rahma Dewi Risnawati, Wahyu Roby Fauzan Samsulaga Safira, lLaurentia Filda Santi Santi Sariningtyas, Rahma Novita Septiani, Erni Dwi Septiyan, Erni Dwi Shafa Sabela Ramadhani Sintia Aisyah Nur Said Stefanus Khrismasagung Trikusumaadi, Stefanus Khrismasagung Suharyanto Suharyanto Tantri Daniawaty Tri Harningsih Tri Harningsih Tri Harningsih Tri Harningsih Tri Harningsih, Tri Trifena Wening Oksani Umi Rahmawati Vindy Widya Kusumaning Tyas Violyn Christiana Wardani, Tatiana Siska Whella Thalitha Larassati Widhiyastuti, Endang Wijayanti Arum Pradita Yaniarty, Setyo Yesti Nanda Sisvitara Yolandita Shintaini Auliya Yusianti Silviani Yusianti Silviani Yusianti Silviani Yusuf Gesha Kesumawijaya Zafira, Azalia Putri