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Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 314 Documents
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FORMULASI DAN EVALUASI SEDIAAN FACIAL WASH EKSTRAK MIMBA (Azadirachta indica A.Juss) Caesa Anjarini, Saniyya; Kurniawari, Darini; Budi, Setia; Audina, Mia
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1519

Abstract

Neem extract is known to have antibacterial activity against acne-causing bacteria. Neem extract is made into facial wash preparations to develop herbal plants into more modern preparations. This study aims to determine the optimal formulation from the results of the physical evaluation and hedonity test and then find out that there are differences from the results of the physical evaluation of neem extract (Azadirachta indica A.Juss) facial wash preparation. The research method used was a pre-experimental laboratory one-shot case study. Physical evaluation tests included organoleptic tests, homogeneity, pH, viscosity, free alkali, foam height/foam stability, free fatty acids and hedonity (favorability test). The results of the research on the organoleptic test obtained optimal results in formula 3 and the results of the homogeneity test obtained a homogeneous preparation. Optimal pH test results in formula 3. Optimal viscosity test results in formula 3. Free alkali test results from the three formulations did not contain free alkali. Optimal foam height/foam stability test results in formula 3. Free fatty acid test results do not meet SNI facial wash standards. The results of the hedonity test showed that formulation 3 was preferred by respondents. The optimal facial wash preparation is formulation 3.
UJI AKTIVITAS ANTIDIARE TABLET EKSTRAK ETANOL DAUN KATUK (Sauropus androgynus L.) Merr. PADA MENCIT PUTIH (Mus musculus) Nurul Fadilah, Nitya; Melinia, Meena; Septiani Agustien, Gina
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1563

Abstract

Diarrhea is a condition in which a person experiences excretion of feces more than 3 times a day accompanied by an increase in volume and dilu­­tion which results in dehydration and even causes death. The aim this study was to determine the antidiarrheal activity of ethanol extract tablets of katuk leaves (Sauropus androgynus L.) Merr. which contains tannins, flavonoids and alkaloids as anti-diarrheal compounds because they can inhibit intestinal motility. This test uses the intestinal transit method which measures the length of the intestine through which the marker passes. The number of mice used was 25 which were divided into 5 groups. The positive control group 1 used loperamide HCl at a dose of 4 mg/kgBW. Group 2 was negative control with tablets without extract, Group 3 with tablet extract 80 mg/kgBW, group 4 tablets with extract dose 160 mg/kgBW and group 4 with tablet extract 320 mg/kgBW. The results of this test show that in formulation 1 it has an activity value of 40.32%, in formulation 2 it is 43.21% and in formulation 3 it is 45.2%. Tablet preparations with the best results were in formulation 3 with an extract dose of 320 mg/kgBW which showed the best results
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN BENALU BATU (Begonia sp) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli Rikha Arliandini; Nur Mahdi; Ani Agustina
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1578

Abstract

Empirically, begonia leaves are used as a treatment for cancer and ulcers.  contains chemical compounds of flavonoids, alkaloids, saponins, tannins and steroids. This study aims to determine the antibacterial activity of ethanol extract of begonia and its effective concentration against Escherichia coli and Staphylococcus aureus bacteria. Extraction with 96% ethanol extract using the maceration method. Phytochemical screening test, antibacterial test using various concentrations of 30%, 50%, 100%, positive control (ciprofloxacin) and negative control (aquadest steril) using the disk diffusion method. The results of the phytochemical screening of begonia extract contain alkaloids, flavonoids and tannins. The results of the antibacterial activity test for Staphylococcus aureus were obtained with an inhibitory zone concentration of 30%, namely 3.75 mm, 50%, namely 4.37 mm, and 100%, namely 4.87 mm. Meanwhile, Escherichia coli bacteria obtained a concentration of 30%, namely 4.37mm, 50%, namely 4.62 mm, and 100% is nm 4.75mm. The diameter of the inhibition zone for the positive control of ciprofloxacin against Staphylococcus aureus bacteria was 40.31mm and Escherichia coli was 44.12mm. The ethanol extract of begonia leaves can inhibit the growth of Staphylococcus aureus bacteria at a concentration of 100% is 4.87mm and Escherichia coli bacteria at a concentration of 100% is 4.75mm
CHARACTERIZATION OF MUNDAR PERICARP (Garcinia forbesii) EXTRACT FROM BANJAR DISTRICT OF INDONESIA Rizki, Muhammad Ikhwan; Triyasmono, Liling; Alfandani, Gina; Hadiah Akbar, Nabila; Khumaira Sari, Anna
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1589

Abstract

The mundar plant (Garcinia forbesii) is a typical fruit of South Kalimantan. The people use mundar empirically as a spice, cosmetic, and medicine. The purpose of this study was to determine the characteristics of mundar extract from Karang Intan and Beruntung Baru districts in Banjar Regency. The collection of plants from two places, plant determination, and extraction with 70% ethanol. The extract was then characterized. The characterization showed that the Garcinia forbesii pericarp extract from both places was dark brown, distinctive odor, sour taste, and thick. Both extracts contained flavonoids, phenolics, tannins, saponins, glycosides, and anthraquinones. The chromatography of both extracts was the same and detected to alpha-mangosten. The extract from Karang Intan district has a yield 59.99%, total phenolic content 0.888%, moisture content 9.78%, total ash content 1.10%, and acid insoluble ash content 0.06%. The extract from Beruntung Baru district has a yield 58.74%, total phenolic content 0.823%, moisture content 9.93%, total ash content 1.59%, and acid insoluble ash content 0.04%. Garcinia forbesii pericarp extracts from from two places have the same organoleptical characteristics, phytochemical compounds, and chromatography patterns. The differences are in yield percentage, total phenolic content, water content, ash content, and acid insoluble ash content.
POTENSI ANTIDIABETIK EKSTRAK ETANOLIK BIJI SALAK (Salacca zalacca) PADA MENCIT PUTIH JANTAN GALUR SWISS (Mus musculus) YANG DIINDUKSI ALOKSAN Rukminingsih, Fef; Maya Octasari, Paulina; Kristi Nadila, Lilis; Aulia Putri, Fayza
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1600

Abstract

Traditional medicine is an alternative treatment for diabetes mellitus. Flavonoids are compounds that have the activity of lowering blood glucose levels. Snake fruit (Salacca zalacca) contains flavonoids. This study aims to determine the antidiabetic potential of snake fruit ethanolic extract (SFEE) on male white Swiss mice. This research is an experimental study that consisted of 2 stages, namely testing the antidiabetic power and testing the hypoglycemia side effects of SFEE. Each stage was tested on 5 treatment groups. The various doses used were 91 mg, 114 mg, and 137 mg of 20g mice. In stage 1, fasting blood sugar checks are carried out on days 0, 3 and 17. Meanwhile, in stage 2, fasting blood sugar checks are carried out on days 1, 7 and 14. The positive control in the stage 1 test was metformin, while the stage 2 test used glibenclamide. The results showed that varying doses of SFEE  91 mg, 114 mg, and 137 mg of 20g mice had antidiabetic power of 62.87%, 68.07%, and 70.98%. The greater the dose of SFEE, the greater its antidiabetic power. However, the larger the dose of SFEE and the longer it is administered, the hypoglycemic effects will occur
POTENTIAL OF CITRUS LEAF EXTRACT (Cymbopogon citratus (DC.) Stapf) AS AN ANTIBACTERIAL INHIBITORY of Staphylococcus epidermidis Karnelasatri, Karnelasatri; Cenwira, Wishia; Andareas, Pangeran; Santoso, Feronia Reni Cyrena
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1601

Abstract

The concerns of antibiotic resistance have increased in recently years, this issue caused by long-term repeated use of antibiotics to treat bacterial illnesses. Lemongrass leaf (Cymbopogon citratus (DC.) Stapf) is one of the natural ingredients that can be used as an alternative antibacterial. The study objective is to determine the antibacterial activity of the ethanol extract of 70% cooking leaves against Staphylococcus epidermidis using diffusion methods. In addition, the Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) of extracts were determined using liquid dilution methods. The results of this study show that extract concentrations of 1,000,000 ppm have a barrier zone in the intermediate category when compared with the positive control, that is, clindamycin. Meanwhile, the MIC value obtained is 1250 ppm, while the MBC value is 5000 ppm. The results of statistical analysis showed that there were no significant differences in the inhibition zone diameter formed between the test concentrations.
ELECTIVE COURSE DEVELOPMENT AND EVALUATION FOR THIRD-YEAR PHARMACY STUDENTS ON PHARMACY HEALTH COACHING IN INDONESIA Alexxander, Alexxander; Puspitasari, Ika; Kristina, Susi Ari; Pratiwi, Restu Dwi
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1603

Abstract

To describe our experiences in developing an elective course for third-year pharmacy students on pharmacy health coaching, as well as to evaluate its effects on students' attitudes, knowledge, and skills. The 3 Co-TEAM models consist of 18 hours of course modules. A multiple-choice and essay quiz was used to assess students' mastery of essential abilities pre and post elective courses. After the last teaching session, students' self-perceived attitude, knowledge, and skills were evaluated through a voluntary survey. Of the 60 students in the third year, only 7 students are willing to voluntarily take the elective course. The development of the curriculum resulted in a course of 3 modules, the duration of each course was 2 hours. Results showed that there was a significant improvement in knowledge overall mean score before and after the course (38.79, SD=7.11 and 81.21, SD=5.34, respectively, p<0.05). The overall mean composite score in the student’s perceived attitudes, knowledge, and skills was increased by 48.35%, 96.43%, 51.91%, respectively; p<0.05. This elective course has proven to be a successful way of educating pharmacy students. We advocate the incorporation of this style of education into the learning process to improve student's learning experiences while still supporting traditional healthcare learning.
ANALISIS KADAR FENOLIK TOTAL DAN FLAVONOID TOTAL EKSTRAK ETANOL KULIT PISANG KEPOK (Musa pradisiaca L) Ariani, Novia; Prihandiwati, Erna; Rahim, Aulia; Milasari, Novi; Fatimah, Nurul
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1614

Abstract

Banana peel is a very large amount of waste material (banana fruit waste). In general, banana peels have not been used optimally. Based on the research results, kepok banana peel contains secondary metabolites in the form of flavonoids, alkaloids, tannins and saponins. This study aims to determine the total phenolic content and total flavonoid content of the ethanol extract of kepok banana skin (Musa pradisiaca L). Extraction was carried out by maceration method with 96% ethanol solvent. Determination of total phenol content used the Folin-Ciocalteu method with gallic acid as comparator compound and the determination of total flavonoid content used the colorimetric method with 10% AlCl3 and 5% acetic acid as reagents. The results showed that kepok banana peel extract had an average total phenolic content of 13.4495 mg GAE/g ± 1.5473206 and an average total flavonoid content of 8.5468 mg QE/g ± 0.947422695.
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN GEL EKSTRAK DAUN BAJAKAH KALALAWIT (Uncaria gambir Roxb.) TERHADAP PROSES PENYEMBUHAN LUKA BAKAR PADA MENCIT PUTIH Ayuchecaria, Noverda; Yohanes Edy Gunawan; Efriyana Oksal; Shesanthi Citrariana
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1635

Abstract

Burns are tissue loss caused by contact with heat sources. Burns will not only cause skin damage, but also affect the entire body system. Bajakah kalalawit contains polyphenolic compounds. This research aims to design a gel preparation formulation that is effective in the healing process of burn wounds in white mice. The preparation was also tested for its physicochemical characteristics including organoleptic test, homogeneity test, pH test, spreadability and stickiness test and irritation test. The results showed that all formulas were homogeneous and no organoleptic changes occurred after 14 days. The pH range of Bajakah gel is 6.16 – 7.46 which meets the skin's pH requirements. The diameter range of spreading power is between 5-7 cm. The adhesion power of formulas 2 and 3 meets the requirements (<4 seconds). The four formulas did not show irritation in the irritation test. The conclusion of this research is that Bajakah kalalawite extract gel with the composition of Formulas 2 and 3 meets the requirements for physical quality characteristic tests including organoleptic, homogeneity, pH, spreadability, adhesive power and irritation test. The diameter of the burn wound showed that there was a significant difference in treatment compared to the negative control group (p<5%).
UJI ANTIBAKTERI BAGIAN MINYAK dan AIR DESTILAT BUNGA KENANGA [Cananga odorata (L.) Hook.F. & Thoms] TERHADAP Staphylococcus epidermidis dan KESETARAANYA PADA TETRASIKLIN HCl Adhe Septa Ryant Agus; Siti Maimunah
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1639

Abstract

Antibacterial tests have been carried out on the oil and water from the distillation of ylang-ylang flowers [Cananga odorata (L.) Hook.F. & Thoms] on the growth of Staphylococcus epidermidis and equivalence to the Tetracycline HCl. using the agar diffusion method and qualitative identification of chemical contents profiles using thin layer chromatography (TLC). For the oil part, there are seven stains in sequences, namely pink, dark green, brown, green blue, red purple, light green, and dark purple, with Rf being 0.13, 0.17, 0.20, 0.38; 0.45, 0.53, and 0.70. Meanwhile, for the water part, three stains formed, namely brown, red, purple, and dark purple, with Rf values of 0.20, 0.45, and 0.70. The equivalent concentration of oil parts for the test solution for the growth of Staphylococcus epidermidis with the reference Tetracycline HCl was 0.563, 0.724, and 0.857ppm. Meanwhile, the equivalent concentration for the water part was 0.413, 0.390 and 0.368ppm. This analysis found that for the oil part of the test solution, there was a significant difference in the inhibitory power of the growth of Staphylococcus epidermidis. At the same time, there was no significant difference in the water. 

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