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INDONESIA
Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 314 Documents
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SKRINING FITOKIMIA DAN UJI ANTIBAKTERI EKSTRAK ETANOL DAUN HANJUANG MERAH (Cordyline fruticose) TERHADAP BAKTERI Staphylococcus epidermidis Ayuchecaria, Noverda; Sri Martani, Natalia; Kartika Komara, Nisa; Chuchita; Pereiz, Zimon; Oksal, Efriyana
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1683

Abstract

Hanjuang Merah (Cordyline fruticosa) is one of the plants used by the Dayak people as traditional medicine. Red hanjuang is an ornamental plant that is very abundant in Indonesia, but there is still not much research that proves the efficacy of red hanjuang. The aim of this research was to determine the phytochemical screening and antibacterial activity of leaf extract of hanjuang merah (Cordyline fruticose) against the bacteria Staphylococcus epidermidis. The method used in sample extraction was maceration, while in the antibacterial test used the paper strip diffusion method with concentrations of 25%, 50%, 75% and 100%. The yield of ethanol extract of hanjuang merah leaf was 11.35%. There was an increase in the diameter of the inhibition zone with the addition of the concentration of ethanol extract of hanjuang merah leaf. The addition of ethanol extract of hanjuang merah leaf at a concentration of 75% sensitive inhibited the growth of Staphylococcus epidermidis bacteria. Secondary metabolites such as tannins, alkaloids, saponins, flavonoids and quinones found in ethanol extract of hanjuang merah leaves are considered responsible for inhibiting the growth of Staphylococcus epidermidis bacteria.
STUDI ETNOMEDISIN DAN SKRINING FITOKIMIA TUMBUHAN BERKHASIAT OBAT DI WILAYAH KECAMATAN MARTAPURA BARAT Rahimah; Rahmi Muthia; Abdurrahman Sidiq
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1687

Abstract

Pemanfaatan tumbuhan sebagai obat terus berkembang hingga saat ini, khususnya tumbuhan yang ada di Wilayah Kecamatan Martapura Barat. Tujuan dari penelitian ini adalah untuk mengetahui spesies tumbuhan obat, mengetahui hasil skrining fitokimia tumbuhan obat dan untuk mengetahui hubungan kesesuaian efek farmakologi dengan studi empiris tumbuhan obat yang digunakan oleh masyarakat di wilayah tersebut. Jenis penelitian adalah penelitian deskriptif dengan analisis data kualitatif dan kuantitatif. Berdasarkan hasil wawancara yang telah dilakukan terhadap 12 responden, terdapat 10 spesies tanaman obat dengan nama lokal dan nama spesies yaitu pakis (Nephrolepis cardifolia (L) C.Presl), bamban (Donax caneformis), dangkak-dangkak (Hydrolea spinosa), jariangau (Acorus calamus Linn.), karamunting laki (Melastoma malabathricum L.), kumpai serampangan (Eleusine indica), lambai-lambai (Cayratia trifolia L.), lelangsatan (Elephantopus tomentosus L.), linjuang (Cordyline fruticosa (L) A. Chev) dan papisangan (Ludwigia octovalvis (Jacq.) P.H. Raven). Bagian tanaman yang digunakan yaitu daun dan akar. Setelah dibandingkan efek farmakologi dengan studi empiris dapat disimpulkan empat tumbuhan berkesuaian dan enam tumbuhan belum ditemukan publikasi ilmiah untuk penelitian terkait. Frekuensi sitasi tertinggi dalam penelitian ini adalah 91,67% pada tanaman bamban, kumpai serampangan, lambai-lambai dan lelangsatan, sedangkan nilai rasio kesepakatan informan tertinggi pada kategori non degeneratif sebesar 0,88.
PENGARUH PEMBERIAN EDUKASI DENGAN MEDIA VIDEO TERHADAP TINGKAT PENGETAHUAN MASYARAKAT KUIN CERUCUK BANJARMASIN DALAM MENGELOLA OBAT RUSAK DAN KEDALUWARSA Mahrita, Mahrita; Saputera, Mochammad Maulidie Alfiannor; Kurniawan, Guntur
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1688

Abstract

In daily life, people use and store medicines at home for self-medication. Medicines that are stored and not used properly can cause drug damage and drugs to accumulate until the expiration date. The purpose this study was to determine the effect of providing education with video media on knowledge in managing damaged and expired drugs in the Kuin Cerucuk Banjarmasin Village community. This study used a pre-experimental research design with a One Group Pretest Posttest approach. The number of respondents this study were 100 respondents who met the inclusion and exclusion criteria. Data collection used a validated knowledge questionnaire and sampling was done door to door. The results study shows the level of knowledge before being given education with video media, namely the good category 9%, the sufficient category 46% and the less category 45%. While the level of knowledge after being given education with video media 80% good category, 20% sufficient category and 0% lacking category. Based on non-parametric tests using Wilcoxon test, it is known that the p value = 0.000 with a significance level <0.05, which means that there a significant (real) influence between the level of knowledge before and after being given education through video media.
PENGARUH ERITROPOETIN TERHADAP TINGKAT KEBERHASILAN TERAPI ANEMIA PADA PASIEN ANEMIA PADA PASIEN CHRONIC KIDNEY DISEASE DI RSUD ULIN BANJARMASIN Wahyunita, Sari; Kurniawan, Guntur; Maharani, Sonia
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1690

Abstract

Chronic kidney disease (CKD) is kidney damage for more than 3 months. The medical  in hospital  taken was hemodialysis. The aim of this study was to determine the success rate of anemia therapy, the incidence of anemia in CKD patients, and determine the effect of erythropoietin administration on the success rate of anemia therapy in CKD patients at Ulin Hospital, Banjarmasin. This research is a non-experimental research, observational in nature. Data collection was carried out prospectively. The sample used in this study was patient hemoglobin data in medical records that met the inclusion and exclusion criteria. The sample selection method used was total sampling. The measurement of therapeutic success used is the patient's hemoglobin data after being given erythropoietin. The research data obtained is displayed descriptively analytically. The research results of 90 patients with CKD (Chronic Kidney Disease). The results obtained were that 50 patients (55.55%) achieved success in anemia therapy and 40 patients (45.45%) did not achieve success in anemia therapy. The incidence of anemia was 90 patients (100%). Based on the analysis of data obtained, there is an influence of erythropoietin on the success of anemia therapy in Chronic Kidney Disease (CKD) at Ulin Regional Hospital, Banjarmasin.
ANALISIS EFEKTIVITAS BIAYA PENGOBATAN HIPERTENSI PADA PASIEN RAWAT JALAN DI KLINIK NURUL HASANAH TAHUN 2022 Akbar, Depy Oktapian; Yaumil, Fairuz; Apdillah Setiawan, Aldi
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1691

Abstract

Hypertension or high blood pressure is a serious medical condition that significantly increases the risk of heart, brain, kidney and other diseases. Prevalence of the population with high blood pressure is 34.11%. The aim of this research is to determine the cost effectiveness between the use of the antihypertensive drugs amlodipine and candesartan in BPJS outpatient hypertension patients at the Nurul Hasanah Kapuas Clinic in 2022. This research uses the CEA pharmacoeconomic method based on the direct medical cost perspective used, namely health service cost data. The results obtained from this research are that amlodipine therapy is more cost effective than candesartan with an Average Cost Effectiveness Ratio (ACER) value for amlodipine of Rp. 156,441.92 and candesartan Rp. 166,527.78.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL 96% DAUN RAMANIA (Bouea macrophylla Griffith.) DARI DAERAH KALIMANTAN SELATAN DENGAN METODE DPPH Saftia Aryzki; Setia Budi; Yanti
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1692

Abstract

Ramania (Bouea macrophylla Griffith.) is a herbal plant that has antioxidant properties and inhibits free radicals. This research aims to determine the antioxidant potential of ramania leaf ethanol extract by looking at the IC50 value. Ramania leaves were extracted using the maceration method using 70% ethanol solvent. Antioxidant potential is determined using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method by comparing vitamin C which has been proven to have very potent free radical potential. The ramania leaves made had a concentration of 10% and then diluted to a concentration of (20,40,60,80,100) µg/mL. 2 mL of each infusion was taken and reacted with 2 mL of 50 µg/mL DPPH solution in an aluminum-lined test tube for a period of time (30 minutes). The results showed that the IC50 value of the ethanol extract of ramania leaves was 0.8126 ± 78.56387 µg/mL. The IC50 value obtained was compared with the inhibition value of the vitamin C solution made with varying concentrations (2,4,6,8,10) µg/ mL, based on this value, ramania leaf extract from the Sleman area is categorized as very potent so it can be developed as a source of antioxidants from natural ingredients.
HUBUNGAN RIWAYAT KERJA TERHADAP PENGETAHUAN VALIDASI DAN KUALIFIKASI BERDASARKAN CPOTB DI USAHA KECIL OBAT TRADISIONAL PT. X di DAERAH ISTIMEWA YOGYAKARTA Banafsaj, Zakia Irbah; Dwinta, Eliza; Emelda, Emelda; Sarwadhamana, Raden Jaka
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1694

Abstract

Validation and qualification are important activities the pharmaceutical industry to produce quality and safe drugs. Good Manufacturing Practices for Traditional Medicines (CPOTB) is a guideline for the traditional medicine industry to produce medicines with guaranteed quality from validation and qualifications. Employee knowledge in carrying out validation and qualifications in the traditional medicine industry is very necessary to support the production quality assurance process. The aim of the research is to determine the relationship between work history (length of work and work area) on validation knowledge and qualifications based on CPOTB in the small business of traditional medicine PT. X in the Special Region of Yogyakarta. The type of research is descriptive quantitative with a cross sectional method. The research uses primary data from questionnaires of 35 employees who work in the production sector of PT. X. The results showed that there was no work history relationship with employee knowledge of CPOTB, with a p-value of 0.496 (<0.05) in the length of work and a p-value of 0.724 (<0.05) in the work area. From the data it can be concluded that the length of work and employee work area in the production sector are not related to employee knowledge of CPOTB.
EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN KECAPI (Sandoricum koetjape Merr) TERHADAP PERTUMBUHAN BAKTERI Enterococcus faecalis Yusrinie Wasiaturrahmah; Muhammad Rayhan; Deby Kania Tri Putri; Agung Satria Wardhana; Maharani Laillyza Apriasari
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1699

Abstract

Penyebab terbesar kegagalan perawatan saluran akar sebesar 63% disebabkan oleh bakteri Enterococcus faecalis. Bakteri Enterococcus faecalis dapat dieliminasi dengan melakukan irigasi saluran akar. Kandungan zat aktif seperti saponin yang terdapat di dalam daun kecapi (Sandoricum koetjape Merr) terbukti memiliki efek antibakteri. Tujuan mengukur dan menganalisis efektivitas antibakteri ekstrak daun kecapi (Sandoricum koetjape Merr) terhadap pertumbuhan bakteri Enterococcus faecalis. Metode penelitian ini merupakan eksperimen murni (true experimental) dengan post test only with control group design. Penelitian ini terdiri dari 9 kelompok perlakuan, yaitu ekstrak daun kecapi (Sandoricum koetjape Merr) konsentrasi 10%, 20%, 30%, 40%, 50%, 60%, 70%, sodium hipoklorit (NaOCl), dan aquadest dengan 3 kali pengulangan. Data KHM didapatkan dari pengukuran delta Optical Density (OD) dan data uji KBM didapatkan berdasarkan perhitungan jumlah koloni. Berdasarkan nilai rata-rata dan analisis data diketahui KHM terdapat pada konsentrasi ekstrak daun kecapi 10% dan KBM pada konsentrasi 20%. Ekstrak daun kecapi (Sandoricum koetjape Merr) konsentrasi 10%, 20%, 30%, 40%, 50%, 60%, dan 70% memiliki efektivitas antibakteri terhadap pertumbuhan bakteri Enterococcus faecalis.
PERBEDAAN AKTIVITAS ANTIOKSIDAN PADA KOLANG KALING SEGAR DAN KOLANG KALING SERBUK Eka Susanti Hanhadyanaputri; Ariani Hesti Wulan; Indah Sulistyarin; Intan Martha Cahyani
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1704

Abstract

Kolang kaling (Arenga pinnata) is one of the results of the palm tree. The process of processing palm fruit into and fro can affect the quality of the fruit and fro produced.  The purpose of this study was to determine the physico-chemical characteristic, IC 50 value of fresh fruit and fro, the powder was dried in the microwave at low temperature (40oC) for 5 days, medium (53oC) for 4 hours and high (78oC) for 2 hours, and to find out whether there are effect of difference in fresh fruit and fro treatment on antioxidant activity.  Fresh fruit and fro were tested for phytochemical screening and FTIR, physicochemical characteristics and antioxidant, Antioxidant testing used the DPPH (1,1-diphenyl-2-picrylhidrazyl) method. The results of phytochemical screening and FTIR showed the presence of galactomanan compounds.  The antioxidant test results obtained the IC50 value of fresh fruit and fro, the powder was dried in the microwave at low temperature, medium and high respectively 104.8488; 25.2963; 90.0155 and163.4381 ppm. The statistical test results showed a value of 0.000<0.05,  there is a difference IC50 between groups
INKORPORASI MIKROEMULSI EKSTRAK ETANOL AKAR KELAKAI (Stenochlaena Palustris (Burn. F) Bedd.) PADA FORMULASI TONER WAJAH DENGAN VARIASI KONSENTRASI GLISERIN Forestryana, Dyera; Muawiyyah, Walidatun; Indah Sayakti, Putri
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1706

Abstract

The face is one part of the human body that needs to be kept healthy and clean. Efforts can be made to maintain facial cleanliness by using facial toner. The extract of kelakai root has activity as an antioxidant. Incorporation of kelakai root extract microemulsion in the toner formulation will increase the cleaning ability and optimal absorption of active substances. This research aims to obtain an optimum face toner formula. The kelakai roots were macerated with 70% ethanol solvent. The kelakai microemulsion consisted of Tween 80 35% w/v and PEG 400 15% w/v. Incorporation of 2% w/v microemulsion into the toner formula with varying glycerin concentrations of 2%, 3%, 4%, and 5% w/v. Evaluation through stability tests with organoleptic, homogeneity, pH, viscosity, clarity, and density. Organoleptic, homogeneity, and clarity before and after the stability test provide a liquid form, odorless, clear, and homogeneous color. In the pH test, the pH value of the preparation was stable in the pH range of 4.5-6.5. The viscosity of toner preparations is in a range of 1-24.5 cPs. The density stability with a range of 1.003-1.015 gr/mL. The optimum formula, namely F2 with 3% glycerin, provides good toner stability based on physical quality tests.

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