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INDONESIA
Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 314 Documents
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OPTIMASI KONSENTRASI TEMULAWAK DAN WAKTU PERENDAMAN SEBAGAI PEREDUKSI FORMALIN PADA TAHU MENGGUNAKAN RESPONSE SURFACE METHODOLOGY Gumilar, Anggi; Dewi, Mira Andam; Salsabila, Nabila Hafna
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1746

Abstract

Tofu is a food product that contains high water which causes the shelf life of tofu to be short. Some manufacturers add preservatives to extend its shelf life. However, some rogue manufacturers add prohibited preservatives such as formalin. Formalin reduction can be done using Curcuma xanthorrhiza, which can reduce formalin through saponification mechanism. This research aims to determine the optimal conditions for formalin reduction using curcuma. Tofu samples that have been contacted with formalin were treated by immersion with a solution of curcuma, then reacted with Schiff’s reagent and measured by spectrophotometer UV-Visible at a maximum wavelength of 556 nm. Optimization was carried out using Response Surface Methodology (RSM) with Central Composite Design (CCD) method. Independent variables that were used in this optimization were concentration of curcuma and soaking time. Data analysis of reduced formalin content was carried out using Minitab version 19. RSM equation for optimization of concentration of curcuma (X1) and soaking time (X2) to obtain the maximum value of reduced formalin is y=19,63–1,70X1–0,368X2+0,2034X12+0,00954X22–0,0052X1X2. The optimization results of RSM showed that the optimal condition was at concentration of 8.53% v/v and immersion time of 51.21 minutes, with a predicted amount of reduced formalin of 23.90 µg/g (45,89%).
UJI AKTIVITAS ANTIDIARE INFUSA KACANG PANJANG (Vigna sinensis L.) TERHADAP MENCIT PUTIH (Mus musculus) JANTAN Inderiyani, Inderiyani; Herdaningsih, Sulastri; Pramana, Yoga; Olivia
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1761

Abstract

Diarrhea is a disorder of defecation more than 3 times a day with a liquid stool consistency, which may be accompanied by blood and/or mucus. This plant has the potential to be used as an alternative treatment for diarrhea, one of which is cowpea (Vigna sinensis L.). Cowpea is a plant that has secondary metabolites in the form of flavonoids, sterols and tannins which are thought to have activity as antidiarrheal. This study aims to determine the activity and dose of cowpea as antidiarrheal against male white mice with oleum ricini-induced diarrhea protection. The test was carried out by inducing mice using 0,75 mL of Ricini oleum orally first, 1 hour later given a test solution in the form of 0,5% Na CMC suspension, 0,52 mg/kgBB loperamide test solution, cowpea infusa doses of 1,5 g/kgBB, 3 g/kgBB and 6 g/kgBB. Then observations were made on the weight of diarrhea feces and the diameter of water absorption every 30 minutes for 5 hours. The results showed that cowpea infusa with doses of 1,5 g/kgBB, 3 g/kgBB and 6 g/kgBB had activity as antidiarrheal indicated by a significant difference in the test group against the negative control group (p ≤0.05).
FORMULASI OBAT KUMUR EKSTRAK DAUN BINAHONG DAN KAYU MANIS TERHADAP BAKTERI Streptococcus mutans Rakhmayanti, Regia Desty; Nur Aisiyah, Astri Dewi
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1781

Abstract

Dental caries is a disease in the oral cavity, this disease can be prevented by using mouthwash. Plants that have antibacterial activities include binahong leaves  and cinnamon . This study aims was to determine the quality and antibacterial activity of mouthwash that containing against Streptococcus mutans. Mouthwash preparations was carried out by various concentrations of binahong leaves and cinnamon extract. Preparation F0 is without extract, F1 (6%:3%), F2 (7%:3%), F3 (8%:3%). The organoleptic test results of the mouthwash was clear brown in color and had a distinctive aroma of binahong leaves and cinnamon. The pH test results were F0 6.529±0.16; F1 5.256±0.004; F2 5.333±0.002; and F3 5.373±0.003. The density measurements results were F0 1.0766±0.04852; F1 1.0309±0.00056; F2 1.0317±0.00032; and F3 1.0364±0.00325. The viscosity measurement results were F0 3.170±0.02; F1 3.203±0.02; F2 3.323±0.01; and F3 3.380±0.02. The antibacterial activity test result were F0 0.00 mm; F1 6.39±0.03 mm; F2 7.29±0.06 mm; F3 8.89±0.07 mm; negative control (distilled water) 0.00 mm; and positive control (chlorhexidine 0.2%) 21.35±0.10 mm. The preparation fulfilled the physical quality parameter requirements of mouthwash and has antibacterial activity against Streptococcus mutans.
PERBANDINGAN SIFAT FUNGISTATIK EFEKTIF ANTARA EKSTRAK DAUN Muntingia calabura DAN Strobilanthes crispa TERHADAP Fusarium sp SECARA IN VITRO Hujjatusnaini, Noor; Muh Amin , Astuti; Nirmalasari, Ridha; Mila; Bunga Nur Siammukaromah, Jamalika; Puteri Maharani, Septia; Alia, Rahmah; Alya Meiana, Nurma; Fatimah
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1801

Abstract

Muntingia calabura L. and Strobilanthes crispa are types of plants that contain flavonoids, saponins and tannins The Fusarium sp fungus infect plants, causing disease in plants. This-study aims to determine the-comparison of the effective fungistatic properties of Muntingia calabura L. and Strobilanthes crispa extracts against Fusarium sp in vitro. This research is experimental research, analyzed statistically using the anova-method, after being tested anova with significant results, it is continued with the Tukey-test, and paired-sample-tests . The adaptability of the Fusarium sp fungus in a-petri dish containing NA-medium which was then added with Muntingia calabura L and Strobilanthes crispa extracts with the same concentration, respectively 75%, 80%, 85%, 90%, 95% and the-addition of control(-) (aquadest) and control(+) (amoxilin) ​​which observed for 3-days. Based on the-results of research that have been made, the measurement of the inhibition zone in Muntingia calabura L. extract with 75% treatment was 1.6mm. And Strobilanthes crispa in the 80% treatment had an inhibition zone of 2.5mm. The 2-tailed sig value was 0.758, this means the sig-value is greater than-0.05 (p>0.05). So it-can be concluded that is no significant difference between the fungistatic activity of Muntingia calabura L extract and the fungistatic activity of Strobilanthes crispa extract.
EVALUASI PENGELOLAAN PENYIMPANAN SEDIAAN FARMASI DI GUDANG INSTALASI FARMASI RSIA IBUNDA PELAIHARI Ilahi, fitrah shafran; Tia Nor Aprilia; Abdul Mahmud Yumassik; Amaliyah Wahyuni
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1819

Abstract

Drug storage in hospital pharmacy installations is a guarantee of the feasibility of drugs received by the hospital before being distributed to patients.  pharmaceutical preparations used by the pharmaceutical installation warehouse at RSIA Ibunda Pelaihari based on the quality standards of the Minister of Health regulation number 72 of 2016 concerning service standards in hospitals. The research method uses a qualitative observational method, the research instrument used in data collection is an observational sheet. The results showed that the storage of pharmaceutical preparations in the pharmaceutical installation warehouse of RSIA Ibunda Pelaihari obtained a figure of 92% which was included in the good criteria based on the results of the calculation of the observation sheet carried out in the pharmaceutical installation warehouse of RSIA Ibunda Pelaihari by showing parts that were in accordance with the Permenkes standard number 72 of 2016, namely storage components, storage system, storage method. While as many as 8% that have not met the standards are the storage requirements and storage equipment. The storage of pharmaceutical preparations in the pharmaceutical warehouse of RSIA Ibunda Pelaihari has met the standards of Permenkes number 72 of 2016 with a percentage of 92% which is in the good category.
HUBUNGAN USIA, JENIS KELAMIN DAN TINGKAT PENDIDIKAN ORANG TUA TERHADAP PENGETAHUAN SWAMEDIKASI PEMBERIAN PARACETAMOL PADA ANAK Farmasita, Rizky; Veronica, Arbella
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1838

Abstract

According to the National General Health News about child health, it is known the prevalence of fever  reaches 33.4%. This makes parents need to take an active role in self-medication efforts to treat children who have a fever. This study aims to evaluate the relationship between age, gender, and level of education with knowledge of self-medication in administering paracetamol to children. The non- experimental research method with a cross-sectional design uses a descriptive approach based on questionnaire data. Data were analyzed statistically using the chi-square test. The study was conducted in Depok, the area of Grand Depok City. The population and sample of the study were parents in Grand Depok City, with 196 respondents. The results of the analysis showed that the majority of respondents were aged 40-59 years, female (147 people), educated in high school/vocational school, employed as private employees (98 people), and had one child (91 people). The level of knowledge  of respondents about paracetamol self-medication is good, with 51% knowing the correct dosage. The  conclusion of the study there is no significant relationship between the demographic of parents and knowledge of self-medication.  
EVALUASI PENGGUNAAN ANTIBIOTIK PASIEN PNEUMONIA DENGAN METODE GYSSENS Gemy Nastity Handayany; Dwi Yuliana
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1866

Abstract

The purpose of this study is to determine the rationality of using antibiotics in pneumonia patients with the gyssens method in the inpatient installation of Nene Mallomo Hospital, Sidrap Regency for the 2021 period. This type of research is descriptive research with a quantitative approach conducted retrospectively. The results of the evaluation of the use of antibiotics based on the gyssens method were obtained the use of appropriate / rational antibiotics (category 0) by 14% and irrational use of antibiotics by 86% which were divided into other antibiotics that were more effective (category IVa) by 67%, the use of antibiotics too long (category IIIa) by 5%, the use of antibiotics too short (category IIIb) by 13% and the use of antibiotics not right dose (category IIa) by 1%. In this study, it can be concluded from the category assessed that the use of antibiotics in pneumonia patients at Nene Mallomo Hospital, Sidrap Regency is irrational.
INTERVENSI APOTEKER MENUNJANG PERBAIKAN PERILAKU BEROBAT PENDERITA HIPERTENSI Ariyani, Herda; Akrom; Alfian, Riza
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1896

Abstract

Based on Riskesdas data (2018), the prevalence of hypertension in South Kalimantan was 10.81% or higher in 2020 compared to the national average of 8.8%. High blood pressure can increase the risk of cardiovascular disease when combined with risk factors like obesity, bad eating habits, smoking, and a sedentary lifestyle. A strategy that incorporates the pharmacist's reminders and motivation through the use of short messaging services (SMS) and modified brief counseling is required to help patients behave better when taking drugs in order to achieve therapeutic success. The purpose of the study is to determine how both interventions affected the drug use of street hypertensive patients at X Hospital Banjarmasin. With a Randomized Pre-test – Post-test Control Group Design, the study project is an experimental quota. The prospective data collection was done on road nursing patients. 34 patients (or 50% of the total) were assigned to the treatment group, and 34 individuals (or 50% of the total) were assigned to the control group, after meeting the inclusion criteria of 68 hypertensive patients. Drug-related behavior questionnaires and interviews were used to gather data. Pharmacists who administered both of these programs found that the treatment group's drug behavior score increased significantly (p<0,05).
VALIDASI METODE PENETAPAN KADAR VITAMIN C EKSTRAK DAUN KEMANGI (Ocimum sanctum L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Kurniawati, Evi; Lestari, Tri Puji
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1916

Abstract

Basil leaves (Ocimum sanctum L.) are a type of wild plant that easy to find. Basil is known to be analgesic, antihyperlipid and has antioxidant properties. Besides, basil is also known to treat stomach and liver diseases. Components known to be found in basil plants include flavonoids, alkaloids, saponins, triterpenoids, steroids, tannins, phenols and vitamin C, that is needed by a person to be able to carry out metabolism properly and develop normally. The aim of the research to validate the determination of vitamin C levels from basil leaf extract. The basil leaf filtrate was identified for vitamin C by a color reaction and then the levels were determined by UV-Vis spectrophotometry which was previously validated with the parameters of accuracy, precision, linearity and selectivity. According to the research results, it is known that the accuracy test meets the percent recovery range in the range of 98-102%, the precision test produces an RSD of less than 2%, the linearity test produces a correlation value (r) = 0.9986 and the selectivity test is good. The method for determining vitamin C levels by Uv-Vis spectrophotometry was validated on parameters that met the requirements of 0.0128% w/w.
POLA PERESEPAN OBAT ANTIDIABETIK PADA PASIEN DIABETES MELLITUS TIPE II DI PUSKESMAS PANDAK 1 BANTUL Rissa, Mexsi Mutia; Amallia Rani Wijayanti
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1929

Abstract

Diabetes mellitus in Indonesia is in the top five countries with the most DM sufferers, namely 19.5 million people and this number will increase to 28.6 million people in 2045. If diabetes is not treated properly loss of vision, kidney failure, nerves, limb amputation, and can cause premature death. This study aims to determine the pattern of prescribing for type II diabetes mellitus medication at the Pandak I Bantul Community Health Center for the period 2022. The research methodology used is descriptive observational with retrospective collection of medical record data with a sample of 90 medical records. The results of research on the prescribing pattern for type II diabetes mellitus drugs at the Pandak I Community Health Center consisted of the use of single diabetes mellitus drugs, namely 73.33% of metformin 500 mg, 24.45% of glimepirid 2 mg and 2.22% of glibenclamide 5 mg. The percentages are based on drug class, namely the biguanide group 73.33% and the sulfonylurea group 26.67%. So the pattern of prescribing medication for type II diabetes mellitus at the Pandak I Community Health Center with the single treatment mostly using metformin 500 mg with the biguanide group is 73.33%.

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