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INDONESIA
Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 314 Documents
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HUBUNGAN KUALITAS HIDUP PASIEN HIPERTENSI DENGAN KARAKTERISTIK DEMOGRAFI MENGGUNAKAN INSTRUMEN EQ-5D DI PUSKESMAS S.PARMAN KOTA BANJARMASIN Yumassik, Abdul Mahmud; Azizah, Nur; Illahi, Fitrah Shafran; Wahyuni, Amaliyah; Aisyah, Noor; Soraya, Soraya
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1932

Abstract

 This disease can affect the patient's quality of life if they do not receive appropriate therapy and risks causing complications which can worsen the patient's quality of life The research method used was observational with a cross sectional design. The population was hipertensive outpatient at the S. Parman Community Health Center for the period March 2023. The sampling technique used consecutive sampling technique to obtain a sample of 84 respondents. The research instrument uses the European Quality of Life 5 Dimensions (EQ5D). Data analysis used the EQ-5D index calculator and chi square test. The results showed that the distribution of respondents' characteristics included female gender (57.14%), age 56-65 (54.76%), high school education (50.00%), housewife occupation (34.52%), long suffering hypertension >5 years (60.71%), comorbidities (50.00%), no history of hypertension (52.38%), and hypertension category level 2 (53.57%). The percentage of good quality of life for hypertensive patients was 91.67%, while the poor quality of life for hypertensive patients was 8.33%. The variables of comorbidities (p-value=0.048) and hypertension category (p-value=0.010) have a significant relationship to the quality of life of hypertensive patients. 
ANALISIS BIAYA PASIEN COVID-19 DI RUMAH SAKIT X KOTA BANJARMASIN Aisyah, Noor Aisyah; Aisyah, Noor; Norhilaliyah, Norhilaliyah; Wahyuni, Amaliyah; Kumalasari, Eka; Yumassik, Abdul Mahmud; Illahi, Fitrah Shafran
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1936

Abstract

COVID -19 is designated as an infectious disease that causes an outbreak and causes a public health emergency. COVID-19 causes death and absorbs significant disease costs. The research aims to determine the average cost of inpatient COVID-19 patients at hospitals in the city of Banjarmasin. This research is a descriptive non-experimental study using observational research methods, data was taken retrospectively to provide an overview of the costs of COVID-19 patients. The research sample is data on costs for inpatient COVID-19 patients in March-April 2020 at Hospital x Banjarmasin City with a sample size of 347 treatment episodes. The research results show that the average cost for a COVID-19 patient per episode of treatment is IDR 13,095,609. The total cost of all episodes of care for hospitalized COVID-19 patients is IDR 4,544,176,469. The first largest cost component that absorbs the most costs is the cost of drugs and medical materials amounting to IDR 1,236,714,000 per component with an average of IDR 3,564,017 per episode of care (27.215%). The second largest cost component is room costs, namely IDR 781,624,400 with an average cost of IDR 2,252,520 per treatment episode (17.20).
SKRINING FITOKIMIA DAN PENGARUH VARIETAS PELARUT TERHADAP KADAR ISOFLAVON RIMPANG TEMULAWAK Dilla, Triani Utami; Emelda, Emelda; Fauzi, rizal
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1945

Abstract

Curcuma Rhizome (Curcuma xanthorriza) is a plant that is usually mixed into herbal concoctions. One of the compounds that play a role is isoflavone. This compound functions as the main antioxidant that prevents radical reactions in lipid oxidation. This research aims to conduct a phytochemical screening of Curcuma Rhizome extract to determine the effect of solvent type on the levels of isoflavone compounds. This research method is true experimental with a post-control design. Data analysis was carried out using statistical tests to see the influence of different solvents on the levels of isoflavone compounds. Based on the results of phytochemical screening, the acetone extract of Curcuma Rhizomes contains flavonoids, steroids, and tannins. However, the results were negative for alkaloid compounds. The hexane extract of Curcuma Rhizomes positively contains alkaloids, flavonoids, steroids, terpenoids, and tannins. negative results for saponin compounds. The isoflavone levels in acetone extract and Curcuma Rhizome extract were 135.32 ppm ±10.73 and 27.72 ppm ±0.86, respectively. Based on the results of the statistical analysis, it shows that there is a significant difference between the isoflavone levels of acetone extract and hexane extract of Curcuma Rhizome (Sig £ 0.05).
FORMULASI SEDIAAN ROLL ON AROMATERAPI KOMBINASI MINYAK ATSIRI KRANGEAN (Litsea cubeba (Lour.) Pers.) DAN MINYAK ATSIRI LAVENDER (Lavandula angustifolia Miller) Chandra, Pra Panca Bayu; Efrilia, Mega; Handayani, Indri Astuti
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1947

Abstract

Krangean and Lavender are natural ingredients producing essential oils. The use of krangean and lavender in the community as perfume ingredients. Krangean essential oil and lavender essential oil contain 1.8 cineol which has potential as aromatherapy. The purpose of the formulation of the Roll on aromatherapy preparation is to determine whether variations in the combination of krangean essential oil and lavender essential oil can affect the test parameters ((organoleptic test, homogeneity test, pH test and favorability test or hedon
POTENSI SUN PROTECTOR FACTOR DAN AKTIVITAS ANTIOKSIDAN SEDIAAN GEL TABIR SURYA ESKTRAK ETANOL DAGING BUAH LABU KUNING (Cucurbita maxima) Indriastuti, Marlina; Meilani, Utari
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1958

Abstract

Yellow Pumpkin (Cucurbita maxima) is a botanical specimen classified within the Cucurbita genus of the Cucurbitaceae family, commonly utilized as a culinary component by the populace of Indonesia. The chemical constituents identified in pumpkins consist of polyphenols, exhibiting the potential to act as agents safeguarding against photodamage owing to their capacity to absorb ultraviolet radiation. The primary objective of this investigation is to establish the Sun Protector Factor (SPF) of sunscreen gels derived from the ethanol extract of pumpkin flesh, alongside evaluating its antioxidative properties. The research methodology employed for this purpose involves the DPPH free radical scavenging technique utilizing UV-Vis Spectrophotometry for quantitative assessments. The gel formulations were devised in three variations, denoted as formula I (15% concentration), formula II (20% concentration), and formula III (25% concentration), with Carbomer 940 serving as an additional ingredient for the base of the preparation. Results from the study indicate that the formulation yielding the highest SPF value was formula III, registering an SPF value of 7.521. Notably, formula III exhibited the most substantial antioxidative activity, positioning it within the moderate efficacy classification.
OPTIMASI DAN FORMULASI SABUN MANDI CAIR UNTUK BAYI DARI MINYAK BUAH ALPUKAT (PERSEA AMERICANA MILL) Yuyun Darma Ayu Ningrum; Widyaningrum, Naniek; Sholeh, Aries Badrus; Aprilianti, Yunita
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1964

Abstract

Halal guarantees are implemented to provide comfort, security and peace of mind for people when using halal products. The active ingredient used in this research is avocado oil (Persea Americana Mill). The formula in this research was determined using the Simple Lattice Design (SLD) method with a True Experimental Laboratory research design. In this research, several tests were carried out on the physical properties of the preparation, namely organoleptic test, pH test, foam stability test, viscosity test and homogeneity test. Based on the recommended simple lattice design (SLD) method, data from 10 evaluation tests of formulation preparations were tested and an optimal formulation was obtained. This formula contains a concentration of 12.5% coconut oil and 17.5% KOH. Overall, the physical evaluation of liquid soap formulations in this study shows that R1, R2, and R3 meet the requirements for baby liquid soap according to established standards. The liquid soap for babies obtained from this research has a characteristic liquid consistency, is yellowish white in color and has a distinctive odor. The achieved pH value, foam stability, viscosity and homogeneity are in accordance with established standards.
FORMULASI SEDIAAN MASKER GEL PEEL OFF DARI EKSTRAK KULIT BUAH PISANG AMBON LUMUT (Musa acuminata Colla) SEBAGAI ANTIOKSIDAN riauwati, Rosa; Nor Latifah; Erlina Fatmasari
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2004

Abstract

Kulit pisang Ambon Lumut mengandung senyawa flavonoid  berpotensisebagai antioksidan. Tujuan penelitian ini membuat  formulasi sediaan masker gel peel off dari ekstrak kulit buah pisang ambon lumut (Musa acuminata Colla)  memiliki aktivitas antioksidan. Basis yang digunakan Carbopol 940, dengan variasi 0,5 %, 0,75 %, dan 1%. Formulamasker gel peel off dibuat penambahan ekstrak kulit buah pisang ambon lumutdiperoleh dari hasil maserasi dengan konsentrasi 0,027 %, 0,082 %, dan 0,138%. evaluasi meliputi organoleptik, pH, homogenitas, Viskositas dan waktu mengering, ujiaktivitas antioksidan dilakukan dengan metode DPPH. Uji kesukaan dilakukan ke respondendengan mengoleskan ke punggung tangan responden. Hasil pembuatan basis yangpaling stabil dengan konsentrasi carbopol 940, sebesar 0,5 %. Hasil evaluasi sediaan yang stabildilihat dari parameter organoleptik, pH, homogenitas, Viskositas, dan waktu mengering selamapenyimpanan 28 hari. Dimana Nilai IC50 Dari ekstrak kulit buah pisang ambon lumut di dapatsebesar 27,467 ppm berdasarkan hasil uji aktivitas antioksidan sediaan masker gel peel off masukdalam katagori kuat dan sangat kuat Baik formula 1, 2, 3 yaitu 53,2 ppm; 44,4 ppm; dan 37,91ppm. Hasil uji kesukaan Masker gel peel off dengan konsentrasi 0,027 % yang paling banyak disukai.
ANALISIS KADAR TIMBAL (Pb) PADA BEDAK PADAT YANG BEREDAR DI BANJARMASIN MENGGUNAKAN METODE SPEKTROFOTOMETRI SERAPAN ATOM Huzaeroh, Anifatu; Lestari, Yulianita Pratiwi Indah; Hayati, Mardia
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2072

Abstract

Pressed powder is a type of cosmetic that is commonly used and its safety must be guaranteed so that it is free from contamination. The aim of this research is to determine the presence of lead (Pb) contamination content in solid powder circulating in Banjarmasin using the absorption spectrophotometry method. atom. The test methods used include qualitative tests using 1 M NaOH reagent and quantitative tests that have been validated using Atomic Absorption Spectrophotometry. The results of the qualitative test showed that the five samples were reactive after being reacted with 1 M NaOH and produced a white precipitate. The method validation test results show that this method has linearity with a value of R=0.9996, LOD=0,019994243 ppm and LOQ=0,06664748 ppm. From the qualitative test, it was found that the five samples were indicated to contain lead, therefore it was continued with quantitative testing. Quantitative test results showed lead levels in samples coded A, B, C, D and E were 3,346 mg/kg; 4,894 mg/kg; 3,920 mg/kg; 3,284 mg/kg; dan 1,829 mg/kg.  It can be concluded that although there is still solid powder that contains lead (Pb), it is still below the safe limit for lead contamination, namely <20 mg/kg.
FORMULASI DAN UJI SIFAT FISIK SEDIAAN KRIM DENGAN VARIASI KONSENTRASI EKSTRAK ETANOL DAUN KELAPA SAWIT (Elaeis guineensis Jack) Idawati, Idawati; Patimah, Raudatul; Ahdyani, Risa
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2073

Abstract

Elaeis guineensis Jack. leaves contain flavonoid compounds which act as antioxidants to protect the body from bad influences that can cause skin damage by free radicals. One of the technological developments to treat that can be assisted by cream preparations. Cream has various advantages, namely that it is easy to spread evenly, easy to clean or wash, practical and works on local tissue, not sticky, especially in o/w creams. The aim of this research was to determine the effect of variations in the concentration of palm oil leaf ethanol extract on the physical properties and antioxidant potential of oil palm leaf ethanol extract cream. Oil palm leaves were extracted using the maceration method using 96% ethanol solvent to produce a thick extract. Palm oil leaf ethanol extract is made in cream dosage form with varying concentrations of palm oil leaf ethanol extract, FI (0.5%), FII (1%), and FIII (1.5%). The cream preparations were tested for physical properties including organoleptic tests, homogeneity, pH, viscosity, stickiness and spreadability. Based on the test results, all cream formulas meet the test requirements for homogeneity, pH, viscosity, adhesion and spreadability according to the requirements for cream preparations for use on the skin.
MOLECULAR DOCKING ANALYSIS AND ADMET PREDICTION Of Caesalpinia sappan COMPOUNDS AS ANTIINFLAMMATORY THROUGH CYCLOOXYGENASE-2 INHIBITION Putri Maisarah, Marisa; Rahmawati; Andika
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2076

Abstract

Selective COX-2 inhibitors have been considered safer treatments than NSAIDs for inflammation from its side effect. Sappanwood was already known for its antiinflammatory activity, but its selectivity towards COX-2 has not been tested. The purpose of this study was to determine the potential activity of compounds in Caesalpinia sappan as anti-inflammatory agents by inhibiting COX-2 and determine their ADMET’s properties through in silico study. Qulified compound from Lipinski’s rule of five evaluation would be continued to the molecular docking using Autodock Tools and ADMET prediction using SwissADME and ADMETLab. Three compounds known to have the best free bond energy (ΔG) values were Caesalpiniaphenol A, Sappankalkon, and Deoxysappanone B with ΔG values respectively (-9.36 ; -9.23 ; -9.02 kcal/mol) and their inhibition constant values of (124.44 ; 172.43 ; 244.75 nM) respectively. Amino acid residues that are known to involve to the formation of hydrogen bonds in ligands are GLN 192 and PHE518. Toxicity results showed that these three compounds were predicted to be neither hepatotoxic nor hERG inhibitors, but 3-deoxysappanone B and sappankalkon was predicted to cause AMES mutagenicity and skin sensitivity. It can be concluded that these third compound has the potential as an inhibitor of the COX-2 enzyme.

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