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INDONESIA
Jurnal Farmasi dan Sains Indonesia (JFSI)
Published by Sekolah Tinggi Ilmu Farmasi Nusaputera
ISSN : 26219360     EISSN : 26863529     DOI : https://doi.org/10.52216
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Neuroscience
Focus and Scope Jurnal Farmasi & Sains Indonesia is an open-access journal that published twice a year by Sekolah Tinggi Ilmu Farmasi Nusaputera. This journal is a media of research publication on all aspects of pharmaceutical & science that is innovative, creative, original and based on scientific. Articles published in this journal about drug discovery, drug delivery systems and drug development with specific field include: 1. Medicinal chemistry 2. Pharmacology 3. Pharmacokinetics 4. Pharmacodynamics 5. Pharmaceutical analysis 6. Drug delivery systems 7. Pharmaceutical technology 8. Pharmaceutical biotechnology 9. Herbal medicines and active components 10. Clinical evaluation of the medicine
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 244 Documents
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Studi Fitokimia Kulit Nanas: Pengaruh Metode Pengeringan terhadap Kandungan Flavonoid Ekstrak Etanol: Studi Fitokimia Kulit Nanas: Pengaruh Metode Pengeringan terhadap Kandungan Flavonoid Ekstrak Etanol Wahyuningtiastuti, Ananta; Bulu, Atalia Tamo Ina; Priamsari, Margareta Retno; Solichah, Ayu Ina
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p188-195

Abstract

Food waste refers to discarded food materials at the final stage of the food supply chain. One such waste product with potential for utilization in traditional medicine is pineapple peel (Ananas comosus (L.) Merr.), which contains various secondary metabolites, including flavonoids, alkaloids, saponins, and tannins. Among these metabolites, flavonoids are well-known for their antioxidant properties. This study aimed to compare the total flavonoid content in ethanol extracts of pineapple peel subjected to two different drying methods. The drying methods used were sun drying and oven drying at 50 °C. The dried pineapple peels were extracted using 96% ethanol through the Soxhlet extraction method. Phytochemical constituents were identified through colorimetric reactions and Thin Layer Chromatography (TLC). The total flavonoid content was determined colorimetrically using AlCl₃ reagent and measured by UV-Visible spectrophotometry at a wavelength of 439 nm, with quercetin used as the standard. The results indicated that the extract yields from the sun-dried and oven-dried samples were 5.60% and 5.75% (w/w), respectively. TLC analysis revealed Rf values of 0.85, 0.80, and 0.91. The total flavonoid content in the sun-dried sample was 35.44 ± 0.55 mgQE/g, while that in the oven-dried sample was 25.40 ± 0.98 mgQE/g. Statistical analysis using the Independent Sample t-test demonstrated a significant difference in total flavonoid content between the two drying methods.
FORMULASI DAN EVALUASI SEDIAAN SAMPO KOMBINASI EKSTRAK BONGGOL PISANG KEPOK (Musa x paradisiaca L.) dan MINYAK KELAPA (Virgin Coconut Oil) Akbar, Nanda Dwi; Cahyaningrum, Nineeteen Yuliya; Setiyaningsih, Wahyu; Solichah, Ayu Ina; Christina, Odilia Dea
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p176-187

Abstract

Shampoo is a hair care product that is used to clean the hair and scalp.Shampoo containing natural ingredients can be an alternative for healthy scalp and hair.The saponin content in the kepok banana hump (Musa x paradisiaca L.) can function as a foamer and a combination of coconut oil (Virgin coconut oil) as a moisturizer (emollient).This research aims to formulate and evaluate a shampoo preparation containing banana weevil extract (Musa x paradisiaca L.) and coconut oil (Virgin coconut oil) in the shampoo preparation. This research is an experimental research. In this research, the formulation of kepok banana weevil extract (Musa x paradisiaca L.) 4%, 8% and 12% and coconut oil (Virgin coconut oil) concentrations of 10%, 12% and 15% were carried out. Extract yield was carried out using the maceration method using 96% ethanol solvent with a ratio of 1: 7.5. Evaluation of the physical properties of shampoo includes organoleptic observations, pH determination, specific gravity measurement, foam height measurement, viscosity and homogeneity testing.Data analysis was carried out using SPSS. Based on research on kepok banana weevil extract (Musa x paradisiaca L.)a thick, reddish brown colored extract was obtained, with a distinctive slightly sweet aroma with a yield of 11.4445% from 400 grams of dried banana weevil. The results of the phytochemical screening of the thick extract of banana weevils were positive for containing saponin compounds. The test results for shampoo preparations F1, F2 and F3 have a cream to brownish cream color, a liquid texture and a coconut banana smell, homogeneous preparations, pH range 6.72 – 8.23; has a foam height of 1.8 – 2.3 cm; viscosity 216 – 250 dPas and specific gravity 0.9569 – 1.0272 g/mL. The results of analysis using One Way ANOVA showed a p value <0.05 in foam height, pH value and viscosity for the three formulas, there were significant differences.This research shows that the addition of banana weevil extract (Musa x paradisiaca L.) and coconut oil (Virgin coconut oil) affects the characteristics of the shampoo preparation.
PENGARUH TINGKAT PENGETAHUAN DENGAN IMPLEMENTASI PROGRAM DAGUSIBU OBAT ANTIBIOTIK PADA MASYARAKAT DI KABUPATEN JEPARA Arofa, Izanur; Suwarni, Sri; Indrasari, Ferika; Saptawati, Tunik; Gloria, Fransisca
Jurnal Farmasi & Sains Indonesia Vol 3 No 2 (2020)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The relatively high use of antibiotics poses a threat to the emergence and spread of antibiotic resistance, there are now several findings that antibiotics have been used freely by the public. These antibiotics are purchased to treat symptoms of flu, fever, cough, sore throat, headache and other minor pain symptoms with a duration of use of less than five days. The level of education and knowledge of the community is one of the causes of this. The DAGUSIBU program (get, use, store and dispose) is the most important thing because knowledge is one way to be able to use medicine, store, get, and dispose properly. The purpose of the study was to determine the effect of knowledge with the implementation of the DAGUSIBU program for antibiotic drugs in the community in Jepara Regency from January to March 2020. This type of research is associative research with observational methods. Data were taken prospectively with a quantitative approach from an action research questionnaire. The sample used amounted to 500 respondents. The sampling technique used purposive sampling. Data were processed with chi square and Wilcoxon statistical tests using the SPSS program. The results showed that after the treatment of counseling with video and exposure to speakers and the provision of brochures on the dangers of antibiotic resistance, there was an influence on the level of knowledge with the implementation of the antibiotic drug DAGUSIBU program in Jepara Regency. as evidenced by the p value of 0.00
PENETAPAN KADAR VITAMIN C PADA BUAH NANAS KALENG (Ananas comocus L.) DENGAN METODE SPEKTROFOTOMETRI UV-Vis DAN TITRASI IODIMETRI Ruwista, Anista; Sugiyo, Warlan; Mahesa, Sandi
Jurnal Farmasi & Sains Indonesia Vol 4 No 1 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Vitamin C has an important role in the human body, namely carrying out its functions such as in the synthesis of collagen, the formation of carnitine, is involved in cholesterol metabolism, become bile acids, and plays an important role in the formation of the neurotransmitter norepinephrine. Vitamin C intake must be obtained from outside the body because this vitamin cannot be synthesized in the body through the biosynthetic pathway. Pineapple fruit is one of the fruits that contain vitamin C. The purpose of this study was to analyze the levels of vitamin C in canned pineapples for which the result of vitamin C on the AKB value on the packaging label were not known using UV-Vis spectrophotometry and iodimetric titration. The method used in the qualitative analysis of vitamin C is identification by color raction using Fehling A and B reagents and KMnO4 reagent. Quantitative analysis of vitamin C using the UV-Vis spectrophotometry method with a wavelength of 0,0031 % while the results from the iodimetric titration methode obtained an average % of vitamin C levels from canned pineapple samples of 0,050 % w/w.

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