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The Avicenna Medical Journal
Published by Universitas Islam Negeri Syarif Hidayatullah Jakarta
ISSN : 27209563     EISSN : 2720 9563     DOI : 10.15408/avicenna.v1i1.15639
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
The Avicenna Medical Journal, the official journal of Faculty of Medicine Universitas Islam Negeri Syarif Hidayatullah Jakarta, presents multidisciplinary scientific papers which describe innovative research spanning the entire spectrum of medical aspects both basic science and clinical aspects. It addresses scientists and researchers to publish novel research that is mechanism-based, hypothesis-driven, and focus on significant issues include, but are not limited to: Basic research and biomedical approach on the disease Clinical research Social and other aspects in the integrated focus on solving medical problems Research may involve either in vitro or in vivo or in silico approaches. The Avicenna Medical Journal receives research articles, review articles, and case reports. Appearing 2 times in a year under peer review, The Avicenna Medical Journal actively participates in solving the medical problem and its related aspects.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 88 Documents
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Reduction in Depressive Symptoms in Patients with Breast Cancer Following Cognitive Behavioral Psychotherapy Intervention Ayunda, Bela Sukma; Sofiya, Sofiya; Sunli, M Iqbal; Palupi, Arini Retno
The Avicenna Medical Journal Vol 5, No 1 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i1.37928

Abstract

Background: Breast cancer, a malignancy in breast tissue has the highest prevalence among women globally. Around 50% breast cancer patients have experienced depression caused by the illness and its treatments, which is alarming due to its effects on the treatment effectiveness and recovery. This study is performed to know the effects of cognitive behavioral therapy in decreasing depressive symptoms in breast cancer patients.Methods:  The researchers followed a structured and systematic approach sourced from seven databases: ScienceDirect, ResearchGate, PubMed, Google Scholar, Biomed Central, Taylor & Francis Online, and Pharmacophore. The keywords used in this study were “Breast cancer” AND “Cognitive Behavioral Therapy” AND “Depression”. The initial search yielded 1.190 journals. After applying the inclusion and exclusion criteria, 11 journals were found that met criteria. The search was limited to randomized controlled trials, assessed using the JBI critical appraisal for risk of bias.Results: The result shows positive outcomes in breast cancer patients with depression comorbidity following the implementation of cognitive behavioral therapy intervention. These positive changes include enhanced problem-solving skills in relation to psychosocial and emotional aspects, improved adaptability to various situations, and decreasing depressive symptoms.Conclusion: Cognitive behavioral therapy is effective in decreasing depressive symptoms in breast cancer patients
The Impact of High Dose Ozone Therapy on Hematological and Biochemical Profiles : An Observational Study Digambiro, Reza Aditya; Parwanto, Edy; Lestari, Indah Widya; Chendrasari, Julian; Setyaningrum, Dyah Ayu Woro; Ilona, Florinda
The Avicenna Medical Journal Vol 5, No 1 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i1.34859

Abstract

Background: Ozone therapy, namely High Dose Ozone Therapy (HDO), has become a versatile medical treatment in several clinical settings. Although it is becoming more well acknowledged, there is still a lack of extensive evidence about the impact of this on hematological and biochemical indicators. This study seeks to address this void by examining the consequences of this phenomenon in a clinical environment.Method: An observational study was done, which followed a structured approach, comprising a total of 100 patients who were selected from the SMC Clinic. Hematological and biochemical indices were evaluated before and after ozone therapy sessions to analyze blood parameters. Two blood samples were obtained at two specific time points: prior to the commencement of the ozone therapy (T0) and after the therapy was finished (T1).Results: Substantial alterations were noted in both hematological and biochemical parameters after the therapy. The hematological changes observed in this study showed a substantial rise in the red blood cell count (p=0.009), hemoglobin levels (p=0.004), and hematocrit (p=0.039), along with a decrease in erythrocyte sedimentation rate (ESR) (p=0.020). Notable biochemical changes were observed, including significant modifications in total plasma protein (TPP) (p=0.008) and lactate levels (p=0.001). Furthermore, there was a noteworthy decrease (p<0.05) in the levels of malondialdehyde (MDA), which is a marker for oxidative stress.Conclusion: HDO exerts a regulatory influence on crucial hematological, biochemical, and oxidative stress factors. These findings indicate that HDO may have therapeutic benefits for treating chronic disorders and cancer. It can improve blood parameters and reduce oxidative stress. The decrease in markers of oxidative stress, such as MDA, suggests a potential reduction in the likelihood of problems associated with oxidative damage in chronic diseases. Nevertheless, additional research is required to validate these findings, investigate their wider therapeutic implications, and comprehend the long-term consequences and safety of HDO therapy.
The Effect of Duration of Use and Hygienity on Microbial Profile of Used Mask Surface Used by Children School in Jakarta Mahrunnisa, Fitria; Suwarsono, Erike Anggraini; Awaliyah, Vina Izzatul
The Avicenna Medical Journal Vol 5, No 1 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i1.34630

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is a respiratory infectious disease caused by the SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) virus. The main medium of transmission of COVID-19 is droplets from the respiratory tract. One way to prevent this is to wear a mask. In the context of good and correct mask use, the duration of mask use is one of the concerns, because a study shows that microbes in the form of potentially harmful bacteria and fungi can be found in the use of masks for a long duration. In addition, dental hygiene is also a factor in the development of microorganisms after wearing a mask. Children aged 0-18 years are vulnerable to contracting Covid-19, especially from family. However, until now there have been no studies conducted to identify the hygiene of masks used by children. The aims of this study is to determine the hygiene profile of masks used by school children by identifying the type, number of microbes and knowing the factors that affect the hygiene of the use of masks by elementary, junior high and high school age children.Methods: This study is a cross-sectional study by conducting interviews and collecting masks that have been worn by elementary school students in Jakarta. The surface of the face side mask was then swabbed and cultured on Nutrient Agar media. Data were analyzed using the Mann Whitney test.Results: The subjects in this study were 62 children with an age range of 7-13 years with the majority being female as many as 34 children (54.84%). This study found that there was no significant difference between the number of colonies based on tooth brushing activities before using a mask and the duration of mask use (p 0.396; p 0.268), while there was a significant difference with dental caries (p 0.041). In addition, there was a significant relationship between the presence of pathogens in the mask and the activity of brushing teeth before using the mask (p 0.027) with an OR value of 3.709 (95% CI 1.288- 10.685), meaning that respondents who did not brush their teeth before using the mask had a 3.709 times chance of having pathogens in the mask they used. Meanwhile, in terms of the presence of pathogens, there was no significant relationship between the presence of pathogens in the mask with dental caries and duration of mask use (p 0.166; p 0.516). The types of bacteria identified were dominated by non-pathogenic bacteria in humans, such as Staphylococcus epidermidis and Staphylococcus aureus. This could have occurred because it was affected by the pH of the skin surface which tends to be acidic, due to the free fatty acids contained in the skin.Conclusion: Dental and oral hygiene using masks is related to the presence of pathogenic microbes in the use of masks to prevent Covid-19 in children.
Factors Affecting Symptoms of Depression and Anxiety among Pregnant Women during COVID-19 Pandemic Syauki, Aqilah Syahrina; Hartati, Hartati; Nurwany, Raissa; Aini, Syarifah
The Avicenna Medical Journal Vol 5, No 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.42114

Abstract

ABSTRACTBackground:  Mental health issues, including anxiety and sadness, are exacerbated by changes in social life. Mood and anxiety disorders, such as depression, may strike pregnant women more often than other women. In light of the current COVID-19 epidemic, this research seeks to determine what variables impact the occurrence of depressive and anxious symptoms in pregnant women.Methods:  This study made use of analytical observational research methods. In the year 2021, primary data was collected from November 1st to the 28th. To collect data, we went to seven different obstetrics clinics and handed out paper questionnaires and online surveys. This study makes use of three distinct measures: the Beck Depression Inventory (BDI), the Fear of COVID-19 Scale (FCV-19S), and the Beck Anxiety Inventory (BAI).Results:  Results showed that out of 308 pregnant women in Palembang, 13.0% had mild depression, 5.2% moderate, and 1.6% severe symptoms. Also, 41.9% of people took part in the study; among them, 31.5% experienced mild to moderate anxiety, 9.1% reported moderate to severe anxiety, and 1.3% reported severe anxiety. In the bivariate analysis, a strong correlation was found between the age of pregnant women and depressive symptoms, a significant association was found between packaging symptoms and abortion history, and a significant association was found between anxiety symptoms and fear related to COVID-19. We found statistically significant connections with all of these variables.Conclusions:  The study's results demonstrated a link between maternal age and depressive symptoms, as well as a history of abortion and anxious symptoms. The research participants also reported higher rates of anxiety and despair when they were afraid of contracting the COVID-19 virus. This highlights the critical need of mental health treatment in this context.
The Differences of Adaptive and Maladaptive Coping Mechanisms on the Intensity of Maternal Pain in the First Stage of Labor Khoirun Nisa, Shofia Maharani; Agustina, Wiwik
The Avicenna Medical Journal Vol 5, No 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.42603

Abstract

Coping mechanisms are strategies that a person uses when facing feelings that make him uncomfortable, such as stress and anxiety. One of the impacts of stress and anxiety can be increased labor pain. The level of coping mechanisms is thought to describe maternal stress and anxiety so that it can be used as a predictor of labor pain. The aim of this study was to determine the differences in the level of coping mechanisms and the intensity of pain in mothers during the first stage of labor. This study used an analytical observational method with a cross-sectional design. Sampling was carried out using purposive sampling. A total of 66 mothers giving birth at PKU Muhammadiyah Delanggu Hospital were included in this research. The results of the Wilcoxon test show that there are differences in adaptive and maladaptive coping mechanisms for first stage labor pain with a p value <0.005 (CI = 95%). The conclusion of this research is that there are differences between adaptive and maladaptive coping mechanisms for first stage labor pain at PKU Muhammadiyah Delanggu Hospital in the period 15 November 2017 to 23 January 2018.
The relationship between conflict with doctors and lack of experience with Death and dying and the level of occupational stress experienced by nurses at Haji Hospital UIN Syarif Hidayatullah Jakarta Agustianti, Erika; Srisantyorini, Triana; Fauziyah, Munaya; Purnamawati, Dewi; Djauharoh, Siti Nur Aisyah
The Avicenna Medical Journal Vol 5, No 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.45001

Abstract

Background and Purpose: This study investigates the relationship between conflict with doctors, lack of experience with Death and dying, and the level of occupational stress among nurses at Haji Hospital UIN Syarif Hidayatullah Jakarta. The aim is to identify contributing factors to workplace stress and inform interventions to improve nurses' well-being and the quality of healthcare services.Methods: A cross-sectional analytical study was conducted involving all 96 nurses at Haji Hospital UIN Syarif Hidayatullah Jakarta. Data was collected using Expanded Nursing Stress Scale (ENSS) to asses hazard psychosocial and Workplace Stress Scale (WSS) to evaluate occupational stress levels through a Google Form. The study examined the association between conflict with doctors and lack of experience with Death and dying (independent variables) and the nurses' reported stress levels (dependent variable).Results: The study revealed a significant association between conflict with doctors and occupational stress (p=0.000), with nurses experiencing conflict being 6.13 times more likely to experience occupational stress (95% CI: 2.337-16.106). A significant relationship was also found between limited experience with Death and dying and occupational stress (p=0.017), with nurses having limited experience facing a 2.07-fold increased risk of occupational stress (95% CI: 1.188-3.612).Conclusion: The occupational stress experienced by nurses at Haji Hospital UIN Syarif Hidayatullah Jakarta is significantly related to conflict with doctors and limited experience in managing Death and dying situations.  
Social Support Build Resilience in Multidrug-Resistant Tuberculosis Patients: A Cross-Sectional Study in MDR-TB Patient Support Group Akbar, Putri Wulan; Rachma, Lailia Nur; Rahmah, Zainabur; Firdaus, Muhammad Iqbal; Nanggali, Bryka Vian
The Avicenna Medical Journal Vol 5, No 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.42615

Abstract

Background: Multidrug-resistant tuberculosis (MDR-TB) patient faces multi-dimensional challenges due to the physical factor, long-term treatment, negative stigma, and psychosocial challenge. Addressing these issues patient requires a resilience. The formation of resilience is influenced by both internal and external factors, including social support. This study purposed to assess the social support impact on resilience in MDR-TB patients. Methods: This study was an observational analytic study with cross sectional design. A total of 33 respondents with MDR-TB confirmed, a member of MDR-TB support group, and under treatment were involved. The social support level was measured using the ISEL-12 (Interpersonal Support Evaluation List) questionnaire, while the level of resilience was assessed using the CD-RISC-25 (Connor-Davidson Resilience Scale). Spearman correlation test in SPSS Ver 24.0 was used to examine the relationship between social support and resilience among patients with MDR-TB. Results: Majority of respondents (17 respondents, 51.6%) have good social support and 23 respondents (69.7%) exhibited a good level of resilience. The Spearman correlation test revealed a significant positive correlation between social support and resilience, with a p-value of 0.030 and a moderate strength correlation coefficient (r) of 0.378. Conclusion: This finding showed that good social support toward MDR-TB patients gives positive impact to patients’ resilience. Thus strengthens the system of social support in support group is important to decrease the psychosocial challenges and help to succeed the treatment.
Overview of the Functions of Ginger Rhizome (Zingiber officinale Roscoe), Black Cumin (Nigella sativa), and Pasak Bumi (Eurycoma longifolia Jack) in Male Infertility Setyaningrum, Dyah Ayu Woro; Anggraini, Kirana
The Avicenna Medical Journal Vol 4, No 2 (2023): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v4i2.32322

Abstract

Background: More than 186 million individuals worldwide from Southeast Asian and African nations are affected by infertility, a common health issue, specifically among men. In Indonesia, the use of "jamu" or herbal preparations derived from a diverse variety of herbal sources remains a widely practiced therapeutic approach. Furthermore, the Research and Development Center of the Indonesian Ministry of Health conducted extensive investigations between 2012 and 2018, including 204 distinct plant species used as stimulants and fertility enhancers. Among the species extensively used by ethnic traditional healers are pasak bumi (Eurycoma longifolia Jack), Pimpinella alpina Kds or Pimpinella pruatjan Molk (purwoceng), ginger rhizome (Zingiber officinale Roscoe), and black cumin (Nigella sativa).Methods: This study was compiled as an overview of ten original articles from PubMed and Google Scholar using keywords related to the effects of ginger rhizome, black cumin, and pasak bumi on male infertility.Results: The three plants were useful for improving sperm parameters by antioxidant activity, and increasing the production of reproductive hormones.Conclusion:These plants had a potential role in treating and protecting male infertility by the antioxidant activities.
Factors Affecting Symptoms of Depression and Anxiety among Pregnant Women during COVID-19 Pandemic Syauki, Aqilah Syahrina; Hartati; Nurwany, Raissa; Aini, Syarifah
The Avicenna Medical Journal Vol. 5 No. 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.42114

Abstract

Background: Changes in social life have a negative impact on mental health, leading to conditions such as depression and anxiety. Pregnant women are particularly vulnerable to mental health disorders, including depression and anxiety. This study aims to identify factors that influence symptoms of depression and anxiety in pregnant women during the COVID-19 pandemic. Methods: Analytic observational research was used in this study. Primary data were collected from November 1 to November 28, 2021. The data collected came from distributing paper questionnaires and online questionnaires at 7 Independent Midwifery Clinics. The measurement instruments used include Beck Anxiety Inventory (BAI), Fear of COVID-19 Scale (FCV-19S), and Beck Depression Inventory (BDI). Results: The results showed that out of 308 pregnant women in Palembang, 13.0% experienced mild depression symptoms, 5.2% experienced moderate depression symptoms, and 1.6% experienced severe depression symptoms. In addition, 41.9% of participants reported anxiety symptoms, which were categorized as mild to moderate anxiety (31.5%), moderate to severe anxiety (9.1%), and severe anxiety (1.3%). There was a significant association found in the bivariate analysis between depressive symptoms and the age maternal women, a significant association of anxiety and depression with abortion history, and a significant association of depressive symptoms and anxiety symptoms with fear related to COVID-19. Conclusions: Research reveals multiple relationships between maternal age and depressive symptoms; between an abortion history and anxiety symptoms; between fear of COVID-19 and the symptoms of depression and anxiety. Counselling in mental health is necessary, especially for pregnant women with high-risk of depression and anxiety.
The Differences of Adaptive and Maladaptive Coping Mechanisms on the Intensity of Maternal Pain in the First Stage of Labor Khoirun Nisa, Shofia Maharani; Agustina, Wiwik
The Avicenna Medical Journal Vol. 5 No. 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.42603

Abstract

Background: Coping mechanisms play a crucial role in managing maternal pain during labor. Understanding the differences between adaptive and maladaptive coping strategies can help improve maternal care and pain management. The aim of this study was to determine the differences in the level of coping mechanisms and the intensity of pain in mothers during the first stage of labor. Methods: A cross-sectional study was conducted on 66 laboring mothers at PKU Muhammadiyah Delanggu Hospital. The intensity of pain was measured using the Visual Analog Scale (VAS), while coping mechanisms were assessed using the Brief COPE Questionnaire. Data analysis was performed using the Wilcoxon test with a significance level of p < 0.005. The results of the Wilcoxon test indicate a significant difference between adaptive and maladaptive coping mechanisms in relation to labor pain intensity (p < 0.005) (CI=95%). Among mothers with mild pain, 76.2% used adaptive coping mechanisms, whereas only 23.8% relied on maladaptive strategies. Similarly, in the moderate pain group, 78.8% used adaptive coping, while 21.2% used maladaptive coping. However, in the severe pain category, the majority (66.7%) used maladaptive coping mechanisms, whereas only 33.3% applied adaptive coping strategies. Results: The study confirms that adaptive coping mechanisms are associated with lower pain intensity during labor, while maladaptive strategies correlate with higher pain levels. Conclusion: These findings highlight the need for healthcare providers to educate and encourage expectant mothers to adopt effective coping strategies to improve maternal comfort and childbirth outcomes. Future research should explore interventions that enhance adaptive coping mechanisms in labor management.

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