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The Avicenna Medical Journal
Published by Universitas Islam Negeri Syarif Hidayatullah Jakarta
ISSN : 27209563     EISSN : 2720 9563     DOI : 10.15408/avicenna.v1i1.15639
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
The Avicenna Medical Journal, the official journal of Faculty of Medicine Universitas Islam Negeri Syarif Hidayatullah Jakarta, presents multidisciplinary scientific papers which describe innovative research spanning the entire spectrum of medical aspects both basic science and clinical aspects. It addresses scientists and researchers to publish novel research that is mechanism-based, hypothesis-driven, and focus on significant issues include, but are not limited to: Basic research and biomedical approach on the disease Clinical research Social and other aspects in the integrated focus on solving medical problems Research may involve either in vitro or in vivo or in silico approaches. The Avicenna Medical Journal receives research articles, review articles, and case reports. Appearing 2 times in a year under peer review, The Avicenna Medical Journal actively participates in solving the medical problem and its related aspects.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 88 Documents
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Occupational Stress in Nurses at Hajj Hospital UIN Syarif Hidayatullah Jakarta: The Role of Conflict with Doctor and Death Exposure Agustianti, Erika; Srisantyorini, Triana; Fauziyah, Munaya; Purnamawati, Dewi; Djauharoh, Siti Nur Aisyah
The Avicenna Medical Journal Vol. 5 No. 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.45001

Abstract

Background: In the demanding healthcare environment, both nurses and doctors are at high risk of experiencing stress, with nurses being particularly vulnerable to various psychosocial hazards. This risk also applies to nurses at Hajj Hospital UIN Syarif Hidayatullah Jakarta, especially following organizational changes and nurse rationalization implemented since 2024. The aim is to identify contributing factors to occupational stress and inform interventions to improve nurses' well-being and the quality of healthcare services. Methods: A cross-sectional analytical study was conducted involving all 96 nurses at Hajj Hospital UIN Syarif Hidayatullah Jakarta. Data was collected using Expanded Nursing Stress Scale (ENSS) to asses hazard psychosocial and Workplace Stress Scale (WSS) to evaluate occupational stress levels through a Google Form. The study examined the association between conflict with doctors and lack of experience with End of life (independent variables) and the nurses' reported stress levels (dependent variable). Results: The study revealed a significant association between conflict with doctors and occupational stress (p=0.000), with nurses experiencing conflict being 6.13 times more likely to experience occupational stress (95% CI: 2.337-16.106). A significant relationship was also found between limited experience with End of life and occupational stress (p=0.017), with nurses having limited experience facing a 2.07-fold increased risk of occupational stress (95% CI: 1.188-3.612). Conclusion: The occupational stress experienced by nurses at Hajj Hospital UIN Syarif Hidayatullah Jakarta is significantly related to conflict with doctors and limited experience in managing End of life situations.
Can Spirituality Protect Medical Students from Psychological Distress? Evidence from a Descriptive-Analytical Study Tjakradidjaja, Francisca A.; Dwiyanti, Sophie
The Avicenna Medical Journal Vol. 6 No. 1 (2025): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v6i1.45195

Abstract

Background: Heightened psychological distress is commonly reported among medical students due to academic pressure, multiple assessments, disrupted sleep, and a competitive learning environment. This study investigates the role of spirituality as a potential protective factor for mental health among first-year medical students. Methods: A descriptive-analytical design was employed, involving 115 students who completed a demographic questionnaire, the Daily Spiritual Experiences Scale (DSE), and the General Health Questionnaire-12 (GHQ-12). Results: A total of 92 valid responses were obtained, resulting in an 80% response rate. Respondents were predominantly female (n = 61, 66.3%), with most aged 18 years (n = 59, 64.1%). Regarding Qur’anic memorization, 43.5% had memorized only a few short chapters, 40.2% had memorized 1-5 juz, and 4.3% had memorized 26-30 juz. Mental health screening indicated that 46.7% had a positive mental state, while 53.3% were categorized as having a negative mental state. Notably, 80.4% of students (n = 74) reported limited levels of spirituality. Statistical analysis revealed a strong positive correlation between spirituality and mental health (r = 0.99; p = 0.00). Conclusion: These findings suggest that higher spiritual engagement may buffer psychological distress and that integrating spiritual approaches into medical education could help mitigate psychological distress in early training stages.
Characteristics of Dermatological and Venereological Diseases in Outpatients at Fatmawati Hospital From 2022 to 2024 Prastiwi, Meiuta Hening; Sujudi, Yufanti
The Avicenna Medical Journal Vol. 6 No. 1 (2025): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v6i1.45414

Abstract

Background: This research aimed to assess the characteristics and prevalence of dermatological and venereological diseases among outpatients at Fatmawati Hospital in Jakarta during the 2022-2024 period. Methods: A retrospective descriptive approach was employed, utilizing the total sampling method. Results: The findings reveal a consistent pattern in the ten most common diseases over the three-year period, including Dermatitis (31.22%), Morbus Hansen (17.03%), Psoriasis (11.70%), Acne Vulgaris (6.86%), Condyloma Acuminata (6.80%), Vitiligo (6.83%), Scabies (5.77%), Syphilis (5.17%), Tinea (4.73%), and Seborrheic Keratosis (3.87%). Conclusion: The research highlights the importance of Fatmawati Hospital as a key teaching institution for both general practitioners and specialists, due to the high number of dermatological and venereological cases observed during the research period. The presence of cases that could be managed at lower-level healthcare facilities also underscores the need for more effective referral systems.
Body Image and Exercise Habits: A Study on UIN Jakarta Female Medical Students (2020-2022) Shafiya, Wilda; Fadhilah, Marita; Suri, Auliyani Andam; Lutfie, Syarief Hasan; Kunarisasi, Sity; Adril, Muhammad Alif
The Avicenna Medical Journal Vol. 5 No. 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.45796

Abstract

Background: Body image refers to an individual's perception of their physical appearance, which may influence self-confidence and exercise habits. During adolescence and early adulthood, significant physical and psychological changes often result in body dissatisfaction, potentially affecting patterns of physical activity. Exercise is a structured form of physical activity intended to promote health and maintain physical fitness. This study aimed to examine the relationship between body image and exercise habits among female medical students. Methods: A quantitative analytic study with a cross-sectional design was conducted involving 100 female medical students in the academic phase (class of 2020–2022) at the Faculty of Medicine, UIN Jakarta. Participants were selected using random sampling. Data on body image and exercise habits were collected using validated questionnaires and analyzed using the chi-square test. Results: The analysis revealed a statistically significant negative association between body image and exercise habits (p = 0.006; p < 0.05). Students with a negative body image were more likely to engage in frequent exercise compared to those with a positive body image. Conclusion: Body image significantly influences exercise habits among medical students. A better understanding of this relationship may support the development of health promotion strategies that foster consistent exercise routines without reinforcing negative body perceptions.
Distinguish Between Perforation or Coronary Cameral Fistula: A Rare Findings during Percutaneous Coronary Intervention Laksono, Sidhi; Angkasa, Irwan Surya; Zheng, Tonni; Hosana, Cliffian; Nurbaeti, Putri; Nokik Stujanna, Endin
The Avicenna Medical Journal Vol. 6 No. 1 (2025): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v6i1.45801

Abstract

Introduction: Coronary cameral fistula (CCFs) is a connection between the coronary arteries and a chamber of the heart. Most of it is accidentally found on coronary angiography. This case report discusses a patient with symptoms in whom CCF was incidentally found on CAG. Case presentation: A 49-year-old male patient came to our hospital to undergo an elective standby coronary angiogram. No plaque was found in the LM and LCx; however, a chronic total occlusion (CTO) in the medial LAD was found, as well as 60% tubular stenosis in the proximal and 75% tubular stenosis in the distal RCA. Drug eluting stent was placed up to 20 atm in mid-distal LAD. However, we found contrast-dye extravasation that emptied directly into the heart chamber from the distal LAD. There’s no any signs of pericardial effusion from the bedside echo thus reinforcing the diagnosis of CCFs. Discussion: CCFs represent rare cardiovascular anomalies characterized by abnormal connections between coronary arteries and cardiac chambers or major vessels. Conclussion: Bedside echocardiography is a rapid modality to differentiate perforation from CCFs and can be performed intra-PCI. Management such as transcatheter closure or surgical ligation, can be performed with their own indications.
A Comparative Study of Academic Performance in Myopic Students With and Without Vision Correction Erfira, Erfira; Febriandriani, Dini; Farida, Nida; Mahrunnisa, Fitria; Ulfah Irawati, Nur Bebi; Hermawati, Luluk; Usman, Muhammad
The Avicenna Medical Journal Vol. 6 No. 1 (2025): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v6i1.46768

Abstract

Background: Vision is the primary way people get information and is crucial for the learning process. The World Health Organization (WHO) reports that 285 million people worldwide are visually impaired, with 42% of cases due to uncorrected refractive errors. School-age children are highly vulnerable to refractive errors, with myopia (nearsightedness) being the most common. A decrease in visual function due to myopia interferes with tasks requiring far vision, such as reading the blackboard, which can negatively impact academic performance. This study aims to compare the academic performance of patients with corrected and uncorrected myopia. Methods: This was a cross-sectional analytic study of 5th-grade elementary school students with myopia in Jakarta during 2023. Data collected included the students' average mid-semester exam scores and their myopia status, determined by visual acuity examinations. Results: Out of 106 respondents, 34% (36 people) had corrected myopia and 66% (70 people) had uncorrected myopia with 35 (33%) respondents having academic performance results below the passing grade. Bivariate analysis of the data using the Chi-square test yielded a p-value of 0.010 (p < 0.05). Conclusion: There is a significant relationship between academic performance results and the incidence of myopia.
The Effect of Empathy on Patient Satisfaction in Hemodialysis Services: A SERVQUAL-Based Cross-Sectional Study Zhafira, Dinnisa Haura; Mimanda, Yona; Maikel , Mahesa Paranadipa; Widyastuti, Tri Nisa
The Avicenna Medical Journal Vol. 5 No. 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.46874

Abstract

Background: Empathy is a fundamental aspect of healthcare service quality and plays a vital role in influencing patient satisfaction, especially in long-term, high-contact treatments such as hemodialysis. Despite its importance, limited research in Indonesia has specifically explored the impact of empathy on patient satisfaction in hemodialysis settings. This study aims to evaluate the effect of empathy on patient satisfaction among individuals receiving hemodialysis at Jakarta Hajj Hospital using the SERVQUAL framework. Methods: A quantitative, cross-sectional study was conducted at Jakarta Hajj Hospital between November and December 2022, involving 118 hemodialysis patients selected through consecutive sampling. Data were collected using a structured questionnaire adapted from the KKP-2017 and SERVQUAL instruments. Statistical analysis included descriptive statistics, followed by assumption tests (normality, linearity, and heteroscedasticity), and simple linear regression using SPSS version 26. Results: The mean empathy score was 3.47 ± 0.63. Simple linear regression indicated that empathy had a statistically significant effect on patient satisfaction (B = 0.701, SE = 0.084, 95% CI [0.535–0.868], β = 0.613, R² = 0.375, p < 0.001). The fitted model was: Patient Satisfaction = 13.24 + 0.701(Empathy). Conclusion: Empathy significantly contributes to patient satisfaction in hemodialysis services. Strengthening empathetic communication and patient-provider relationships may enhance service quality and overall patient experiences in chronic care environments.
Social Support Build Resilience in Multidrug-Resistant Tuberculosis Patients: A Cross-Sectional Study in MDR-TB Patient Support Group Akbar, Putri Wulan; Rachma, Lailia Nur; Rahmah, Zainabur; Firdaus, Mohammad Iqbal; Nanggali, Bryka Vian
The Avicenna Medical Journal Vol. 5 No. 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.46875

Abstract

Background: Multidrug-resistant tuberculosis (MDR-TB) patient faces multi-dimensional challenges due to the physical factor, long-term treatment, negative stigma, and psychosocial challenge. Addressing these issues patient requires a resilience. The formation of resilience is influenced by both internal and external factors, including social support. This study purposed to assess the social support impact on resilience in MDR-TB patients. Methods: This study was an observational analytic study with cross sectional design. A total of 33 respondents with MDR-TB confirmed, a member of MDR-TB support group, and under treatment were involved. The social support level was measured using the ISEL-12 (Interpersonal Support Evaluation List) questionnaire, while the level of resilience was assessed using the CD-RISC-25 (Connor-Davidson Resilience Scale). Spearman correlation test in SPSS Ver 24.0 was used to examine the relationship between social support and resilience among patients with MDR-TB. Results: Majority of respondents (17 respondents, 51.6%) have good social support and 23 respondents (69.7%) exhibited a good level of resilience. The Spearman correlation test revealed a significant positive correlation between social support and resilience, with a p-value of 0.030 and a moderate strength correlation coefficient (r) of 0.378. Conclusion: This finding showed that good social support toward MDR-TB patients gives positive impact to patients’ resilience. Thus strengthens the system of social support in support group is important to decrease the psychosocial challenges and help to succeed the treatment.
Balb/C Mice Optimization as Triple Negative Breast Cancer ModelWith 4T1 Cells and 4T1 Cells 3D Culture Inoculation Methods Zafrullah, Umar Farooq; Mubarika Haryana, Sofia; Nugrahaningsih, Dwi Aris Agung; Satriyo, Pamungkas Bagus; Rocca, Matteo
The Avicenna Medical Journal Vol. 6 No. 1 (2025): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v6i1.46877

Abstract

Background: Triple Negative breast cancer (TNBC) is a subtype of breast cancer with negative expression of Progesterone Receptor (PR), Estrogen Receptor (ER), and Human Epidermal growth factor Receptor 2 (HER-2). Among other types of breast cancer, TNBC has a high rate of malignancy and recurrence, invasive, distant metastases, and resistance to conventional therapy. An optimal TNBC model is needed for drug discovery research in targeted therapy. However, optimizing the TNBC animal model by inoculating the 4T1 tumor cell line has a number of challenges and it is quite hard to be developed, especially in Indonesia. Methods: This quasi-experiment study used 28 Balb/c mice divided into four groups (7 mice respectively), group A (injected with basal medium), group B (injected with 4T1 cell), group C (injected with 4T1 cell + Geltrex), and group D (injected with 3D Culture 4T1 cell + Geltrex). After being injected, mice were followed up for 35 days. Once a week they had to be observed by measuring body weight and tumor volume. After 35 days, mice were sacrificed. Liver, lung, brain, and mammary gland were analyzed histopathologically with Hematoxylin-eosin (HE). Chi-square statistical analysis was done to compare intergroups. Results: Histopathologically, there was a group that found positive samples of Invasive Ductal Carcinoma (IDC)-like with a percentage of 28. 57% (2 out of 7), namely group C. Meanwhile, group B and D did not find any positive samples of TNBC, but in the mammary tissue, there was inflammation and epithelial hyperplasia. No distant metastases were found in the liver, lungs, and brain, however, there was inflammation in these secondary organs. Statistically, there was no significant difference between treatment groups with p-value = 0.41. Conclusion: The 4T1 cell inoculation method can produce IDC-like on HE with an incidence of 28.75% (2 of 7 individuals) in group C.
Time-Dependent Secretion of IFN-γ, TNF-α, Perforin, and Granzyme-B in CTL-Conditioned Medium from Colorectal Cancer Patient Ibrahim, Sugeng; Putra, Agung; Hidayah, Nurul; Khan, Ahmed Faheem; Nugraha, Dendi Krisna
The Avicenna Medical Journal Vol. 6 No. 1 (2025): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v6i1.46889

Abstract

Background: Cytotoxic T lymphocytes (CTLs) are key effectors of adaptive immunity, exerting their functions through the release of pro-inflammatory cytokines and cytotoxic molecules. Conditioned medium (CM) derived from CTLs has emerged as a potential cell-free immunotherapeutic strategy; however, the temporal dynamics of its secreted mediators remain poorly defined. Methods: Human CTLs were isolated, activated, and cultured in vitro. CM was harvested at defined intervals (days 5, 10, and 15). Concentrations of interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), perforin, and granzyme-B were quantified by enzyme-linked immunosorbent assay (ELISA). Temporal secretion profiles were evaluated using ANOVA with post-hoc analysis. Results: IFN-γ and TNF-α exhibited peak secretion at day 5, followed by a decline at later time points. In contrast, perforin and granzyme-B increased progressively, reaching maximal levels at day 15. All four mediators demonstrated significant time-dependent variation (p < 0.05). Conclusion: CTL-derived CM displays distinct time-dependent secretion patterns, with cytokines predominating during early activation and cytotoxic molecules dominating later phases. These findings underscore the importance of optimizing CM collection timing to maximize its immunomodulatory and therapeutic potential, and provide a rationale for further translational development of CTL-CM in immunotherapy.

Page 7 of 9 | Total Record : 88

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