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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 429 Documents
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UJI STABILITAS FISIK LOTION ANTI NYAMUK KOMBINASI MINYAK LAVENDER (Lavandula angustifolia) DAN MINYAK ROSEMARY (Rormarinus officinalis) Sari, Devi Amelia; Ambari, Yani; Ningsih, Arista Wahyu; Rahmawati, Dewi
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1680

Abstract

Lavender essential oil 15% can be used as an anti-mosquito protection power on average 56% at 6 hours. Rosemary has a more fragrant aroma and can make mosquitoes uncomfortable and avoid it. This study aims to determine physical stability of mosquito repellent lotion. Lavender oil mosquito repellent lotion (Lavandula angustifolia) and rosemary oil (Rosmarinus officinalis) made in 3 formulas, namely F1 containing lavender oil (10%), F2 (15%), and F3 (20%), and F1 containing rosemary oil (30%), F2 (25%), and F3 (20%). Mosquito repellent lotion was tested for its physical stability using the cycling test method which included organoleptic, homogeneity, pH, adhesion, and spreadability. In this research, citronella and lavender oils can be formulated into anti-mosquito lotions. The results of physical stability (organoleptic, pH, homogeneity, spreadability and adhesion) using the cycling test method show that the anti-mosquito lotion did not change during storage and the results were in accordance with the expected specifications. It can be concluded that the difference in the concentration of lavender and rosemary essential oils does not affect the stability test of the anti-mosquito lotion preparation.
ANTIHIPERURESEMIA FLAVONOID DARI EKSTRAK ETANOL PELEPAH DAUN NIPAH (Nypa fruticans.Wurmb) Raharjo, Danang; Dwi S, Anita; Ardiyantoro, Bagas
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1681

Abstract

Hyperuresimia or gout in advanced stages causes joint damage (gout), kidney stones and kidney damage. Flavonoids as antioxidants can inhibit the activity of the enzyme xanthine oxidase which causes uric acid not to form. Nypa fruticans or known as nipah is traditionally used in the treatment of asthma, leprosy, tuberculosis, sore throat, liver disease, snake bites, as a pain reliever, as a sedative and carminative. The content of flavonoid compounds in nipah plants includes chlorogenic acid, protocatechuic acid, kaempferol, gallic acid, hydroxybenzoic acid, rutin, quercetin, cinnamic acid, and anthocyanins. The purpose of this study was to isolate flavonoid compounds that have potential as antihyperuresemia from nipah fronds. The research process began with the extraction of nipah leaves using 96% ethanol by maceration, fractionation using liquid-liquid partition method, isolation using centrifugal chromatography (chromatotron) method and structure elucidation using 1HNMR, 13CNMR, FTIR and GC-MS. Antihyperuresemia testing was carried out in-vitro by inhibiting xanthine oxidase enzyme activity. From the results of the study, two flavonoid compounds were successfully isolated including (-) epicatechin, and chamferol. The results of measuring the inhibitory activity of xanthine oxidase enzyme obtained IC50 values of (-) epicatechin and chamferol of 3.543 ppm and 10.383 ppm, respectively.
UJI EFEKTIVITAS DAN STABILITAS HAIR TONIC EKSTRAK BAWANG MERAH (Allium cepa L.) SEBAGAI PERANGSANG PERTUMBUHAN RAMBUT Kartika Sari; Laurensia, Vivi; Bachri, Nurjannah; Mukhsin, Achmad; Indrawati, Teti
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1697

Abstract

External skin protection is one of the functions of hair, hair loss and even baldness are common problems. This condition is caused by two factors, namely genetics and the surrounding environment. Shallots (Allium cepa L.) are tubers that are used as a spice and medicine. The flavonoid and phenol content as antioxidants can rejuvenate and repair damaged hair cells, quercetin and kaempferol increase hair growth and prevent hair loss. This research aims to obtain a hair tonic preparation that has activity as a hair fertilizer and to obtain a hair tonic preparation that has good stability, is safe and efficacious. This research used experimental methods, effectiveness testing with Tanaka and accelerated stability testing. The effectiveness test results of healthy control, negative control, positive control, F2, F3 and F4 on the 21st day showed values respectively 12.8, 12.55, 17. .2, 16.5, 14.45 and 12.2 and stability test pH 5.73-6.82, density 0,990-1,031, brown color, liquid form, aromatic smell. The results showed that the preparation with F2 had the same results as the positive control and had a stable preparation in stability testing for 28 weeks.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETIL ASETAT DAUN KARAMUNTING (MELASTOMA MALABATCHRICUM L.) DENGAN METODE ABTS Muthia, Rahmi; Azhari, Fajar; Bin Jamaludin, Wahyudin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1700

Abstract

Antioxidants are compounds that function to neutralize oxidized compounds by capturing free radicals in the body so that they do not cause disease. Due to the negative effects of synthetic antioxidants, people use other alternatives with natural antioxidants found in plants. Karamunting leaf extract has great antioxidant activity. To determine the secondary metabolite content contained in the ethyl acetate extract of caramunting leaves and determine the IC50 value obtained from the antioxidant activity test of caramunting leaves. Identification of compounds using phytochemical screening methods. This antioxidant test method uses ABTS reagent (2,2-azinobis-3-ethylbenzothiazoline-6-sulfonate) and potassium persulfate which are analyzed with a UV-Vis spectrophotometer. The comparator used was quercetin. The results of phytochemical screening showed that the ethyl acetate extract of caramunting leaves (Melastoma malabathricum L.) contained alkaloids, flavonoids, phenols, saponins and steroids. The results of determining λmax are 745 nm and the operating time measurement results are 38 - 42 minutes. The IC50 values ​​of ethyl acetate extract of caramunting leaves and quercetin were 2.2419 µg/mL and 2.6821 µg/mL respectively. The antioxidant activity of ethyl acetate extract of caramunting leaves is classified as very strong.
DAUN Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz SEBAGAI ANTI-Escherichia coli: STUDI IN SILICO DAN IN VITRO Ramadhan, Hafiz; Forestryana, Dyera; Jamaludin, Wahyudin Bin; Hadi, Ahmad Nur; Raudatunnisa
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1701

Abstract

This research was conducted to determine the potential of phytochemical contents in producing antibacterial activity from 70% ethanol extract of Balik Angin leaves  (Alphitonia incana (Roxb.) Teijsm . & Binn. ex Kurz) against Escherichia coli bacteria in silico and in vitro. In silico assay of 20 compounds contained in Alphitonia species against the DNA gyrase receptor using PLANTs. Anti-E.coli activity assay of Balik Angin leaves macerated with 70% ethanol solvent using the Well diffusion method. In silico studies show that β-Sitosterol, Stigmasterol, Rutin, Kaempferol 3-O-rutinoside, and Zizyphoiside C have binding energies with DNA gyrase that can exceed Ciprofloxacin. The antibacterial assay results at a highest concentration of 26.56 mg/ml can provide an average inhibitory zone diameter of 12.75 ± 0.2 mm with a minimum inhibitory concentration (MIC) of 1.66 mg/ml (5.87 ± 1.5 mm). The 70% ethanol extract of Balik Angin leaves has the potential as an anti-Escherichia coli, supported by the content of phytochemical compounds that can act as DNA gyrase inhibitors.
PENGARUH LABEL HALAL, HARGA DAN KUALITAS PRODUK TERHADAP KEPUTUSAN PEMBELIAN YANG BERDAMPAK PADA MINAT BELI ULANG PRODUK SABUN PEMBERSIH WAJAH X DI JABODETABEK DAN SURABAYA Risetyaningsih, Ayunanda; Yantih, Novi; Derriawan, Derriawan
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1702

Abstract

One of the determining factors in repurchasing a product is the halal factor. Especially for the people of Indonesia is one of the country with the largest Muslim population in the world. Because of this, the government issued Republic of Indonesia Law Number 33 of 2014 concerning Guaranteed Halal Products, that not all products circulating in society are guaranteed to be halal. X facial wash is one of the products that has received a halal certificate and Top Brand Award for 3 consecutive years (2020-2022) in the first place for facial wash category. This study aims to determine whether there is an effect of the halal label, price, and product quality on purchasing decisions and whether there is an impact on repurchasing intention for X facial wash. The method used is descriptive quantitative and collecting data through questionnaires. Data analysis using SEM (Structural Equation Modeling) technique. The number of respondents was 235 people who had purchased and used X Facial Wash product during the last 6 months. Data analysis shows that halal label, price, and product quality have an effect on purchasing decisions, but have no effect on repurchasing. This means the existence of a halal label, affordable prices, and the quality of X facial wash products are the determining factors for consumers to purchase products, but not for repurchasing. The halal label, price and product quality can be used to determine consumers' purchasing decisions, but for repeat purchases, efforts are still needed to dig deeper into the determining factors.
PENGARUH BRAND IMAGE, KUALITAS PRODUK, DAN HARGA TERHADAP KEPUASAN PELANGGAN SERTA DAMPAKNYA PADA PEMBELIAN ULANG Erniati, Tri; Yantih, Novi; Widyastuti, Sri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1703

Abstract

The development of cosmetic products and increasingly fierce competition between brands make it necessary for cosmetic brands to be able to maintain and increase product purchases by customers. This study aims to provide scientific evidence regarding the influence of brand image, product quality, and price on customer satisfaction and its impact on repurchase of cosmetic skin care products. The method used in this research is descriptive quantitative verification. The research sample consisted of 255 respondents and was analyzed using SEM (Structural Equation Modeling) with LISREL software version 10.2. The results showed that brand image and price have a significant effect on customer satisfaction, while product quality has no significant effect on customer satisfaction. Brand image, product quality, price and customer satisfaction have a significant effect on repurchase of cosmetic skin care products. Brand image and price are the main factors that can influence customer satisfaction, while product quality is not the main consideration that influences customer satisfaction for cosmetic skin care products. Brand image, product quality, price and customer satisfaction are important factors that encourage customers to repurchase cosmetic skin care products.
AKTIVITAS ANTIBIOFILM DAN ANTIBAKTERI DAUN BINAHONG (Anredera cordifolia (Ten) Steenis) TERHADAP Pseudomonas aeruginosa Fradine, Chossy; Ismi Rahmawati; Opstaria Saptarini
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1705

Abstract

Plant in Indonesia that has antibacterial activity is binahong (Anredera cordifolia (Ten.) Stennis). Binahong leaf contains flavonoid, saponins, tannins and terpenoids compounds. The purpose of the study are determining the potential of extracts and fractions (n-hexane, ethyl acetate and water) in inhibiting the formation of biofilms, biofilm degradation and the value of P. aeruginosa bacterial MBC and to determining the working location of the most active binahong leaf fraction. Binahong leaf is extracted by using maceration method with ethanol as solvent. Then the viscous extract is fractionated with n-hexane, ethyl acetate and water. Antibiofilm activity test is carried out using a microplate and absorbance readings using a microplate reader at a wavelength of 595 nm. The antibacterial activity test uses the dilution method. The IC50 value of the biofilm inhibition test on the extract, water fraction, ethyl acetate and n-hexane for P.aeruginosa bacteria was 0,94; 1,21; 1,03; 0,78. The EC50 value of the biofilm degradation test on the extract, n-hexane, ethyl acetat, water e for P. aeruginosa bacteria is 10,95; 16,06; 12,35; 5,92. The minimum bactericidal concentration value of binahong leaf water fraction for P. aeruginosa is 512 mg/ml.
STUDI KUALITATIF PERSEPSI APOTEKER DAN KADER KESEHATAN DALAM PEMANTAUAN OBAT ANTI TUBERKULOSIS DI PUSKESMAS MLATI II SLEMAN Nurfadilasari, Ulfa Mustofa; Perwitasari, Dyah Aryani; Ghozali, MT; Supadmi, Woro
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 1 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i1.1714

Abstract

Background: Long-term treatment of tuberculosis can cause side effects that cause concern for patients. The side effects experienced by patients have an impact on treatment compliance and drug withdrawal. Efforts to control drug withdrawal require the role of pharmacists and cadres in monitoring treatment. Objective: to explore the perception of understanding and actions of pharmacists and cadres in monitoring anti-tuberculosis drugs. Method: This study is qualitative study with a case study approach. Participants selection using purposive sampling namely pharmacists, cadres and TB program holders who are involved in monitoring TB treatment. The number of participants was six people. Results: interview transcripts were analyzed thematically using software QSR NVivo 12. We categorized into three themes : drug side effects, medication adherence, and treatment success. Conclusion: pharmacists' understanding and actions in monitoring TB treatment are good. While the cadres' understanding and actions regarding the side effects of drugs are not good enough, the importance of compliance with taking medication and the success of treatment is good
ANALISIS BIAYA DAN RASIONALITAS TERAPI PARU OBSTRUKTIF KRONIK DI RSU ANWAR MEDIKA SIDOARJO Lorensia, Amelia; Jalmav, Marthy Meliana; Yorasaki, Yosy Athaya; Saputra, I Nyoman Dodi; Gitaputri, Putu Aprilya
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 1 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i1.1716

Abstract

COPD is the main cause of death, and is currently the fifth cause of death in the world. COPD patients experience decreased capacity for quality of life, physical disability and increased costs of living. In COPD patients, the use of more than one drug therapy and long-term use can carry the risk of drug-related problems. The aim is to analyze the costs and rationality of treating COPD exacerbations. The research design was retrospective to determine the costs and description of therapy for COPD patients at RSU Anwar Medika Sidoarjo. The variables are real costs, INA-CBGs rates, severity and treatment therapy. The research sample was inpatients with BPJS insurance who were diagnosed with COPD attacks at RSU Anwar Medika Sidoarjo for January 2019-December 2021, using the total sampling method. The data collection by observing research materials including medical records. Data analysis is descriptive for data analysis and the incidence of drug-related problems (MTO), and the Mann-Whitney test to determine significant differences between real hospital costs and INA CBG'S inpatient rates. The number of respondents involved was 81 people. The highest components of direct costs incurred by COPD patients during hospitalization are hotel room costs and the cost of consumable medical materials. There was no difference in real costs compared to the rates INA-CBG's (p=0.158). The total incidence of MTO that occurred was 83 cases consisting of inappropriate drug selection (19.27%), drugs without indications (66.26%), inappropriate drug combinations (4.81%), indications without drugs (2 .40%), too many drugs for  same indication (7.22%).

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