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Journal of Health and Nutrition Research
Published by CV Media Publikasi Cendekia Indonesia
ISSN : -     EISSN : 28299760     DOI : https://doi.org/10.56303/jhnresearch
Core Subject : Health,
Medicine & Pharmacology Nursing Public Health
The Journal of Health and Nutrition Research (ISSN: 2829-9760) is an international peer-reviewed, scientific, and open-access journal managed by Media Publikasi Cendekia Indonesia. Journal of Health and Nutrition Research aims to provide forum exchanges and interfaces between researchers and related practitioners in the field of medicine, health, and nutrition. The journal only accepts articles from original research, review articles, and case study articles. Journal of Health and Nutrition Research is a scientific journal and focuses on medicine, health, and nutrition including: Medical and clinical research, Public health research Nursing research Food and nutrition research, Midwifery research Pharmacy research
Arjuna Subject : Keperawatan - Nutrition and Dietetics
Articles 51 Documents
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Search results for , issue "Vol. 4 No. 3 (2025)" : 51 Documents clear
Procedure-Specific Effectiveness of Warmed Versus Room-Temperature Irrigation Fluids for Preventing Perioperative Hypothermia: A Systematic Review Harlasgunawan, Alia Rahmi; Kosasih, Cecep Eli; Nuraeni, Aan
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.525

Abstract

This study investigates the impact of using warmed irrigation fluid over room-temperature fluid on patient body temperature during surgery, while also exploring the variables that influence its effectiveness. Systematic review following PRISMA guidelines. Comprehensive searches were conducted in PubMed/MEDLINE, Embase, Cochrane Central, and Web of Science (inception to March 2024) using PICO framework-derived search terms. Inclusion criteria: randomized controlled trials (RCTs) and systematic reviews comparing warmed irrigation fluids (≥36°C) versus room temperature in adult surgical patients. Quality assessment used Joanna Briggs Institute (JBI) critical appraisal tools. Data synthesis included descriptive analysis and meta-analysis where appropriate. Ten studies (eight randomized controlled trials and two systematic reviews/meta-analyses) met inclusion criteria, comprising 2,459 participants across various surgical procedures. Overall methodological quality was high (mean JBI score 10.2/11, 93%). Effectiveness analysis revealed that 67% of individual studies (6/9) demonstrated significant benefits, with clear procedure-specific patterns. Arthroscopic shoulder surgery showed the highest success rate (75%, 3/4 studies) with effect sizes of 67–80% reduction in hypothermia incidence when using 37°C irrigation. TURP procedures demonstrated conditional effectiveness (50% success rate) depending on anesthesia type, while laparoscopic surgery showed no benefit (0% success rate) due to competing heat loss mechanisms. Warmed irrigation fluids at 37°C demonstrate procedure-specific effectiveness, with arthroscopic shoulder surgery showing highest success rates (75%) and laparoscopic surgery showing no benefit.
Metabolic Diseases Predictor Analysis Based on Single Nucleotide Polymorphisms and Lifestyle Factors: Preliminary Study in Indonesia Subali, Dionysius; Setiawan, James; Kimberly, Patricia; Dijaya, Rendy; Kartawidjajaputra, Felicia; Antono, Lina; Christos, Revelo Eved; Wibisana, Lenny Mulianie; Shih, Yang-Chia
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.527

Abstract

Type 2 Diabetes Mellitus (T2DM) and cardiovascular disease (CVD) emerged as a cause of high mortality rates in low-middle-income countries, including Indonesia. Understanding predictor variables to the commonly used biomarkers, including lipid profiles and blood glucose levels, can thus be beneficial in disease prevention strategies. To support that, this study aims to analyze the genetic, lifestyle, and disease history variables as predictors towards lipid and blood glucose profiles. The respondent’s data were collected from clinical data, food recall, health history, and genetic profiling. From the results, APOA5 rs662799 is positively correlated with triglyceride (TG) levels. Sugar, fat, fiber, and calorie intake also significantly affect lipid and blood glucose profiles. Exercise conditions such as aerobic and flexibility exercise duration significantly correlated with low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) profiles. Disease history in individuals and families emerged as additional variables associated with the response variables. These findings can serve as a preliminary study for understanding health predictors that can be used to predict incident of metabolic diseases in the Indonesian population.
The Effect of Working Posture on Physical Fatigue Among Textile Workers with Age, Length of Service, and Body Mass Index as Covariates Sumardiyono, Sumardiyono; Suratna, Farhana Syahrotun Nisa; Chahyadhi, Bachtiar; Widjanarti, Maria Paskanita; Wijayanti, Reni; Ulfah, Nur
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.533

Abstract

Physical fatigue among textile workers is caused by non-ergonomic working postures (e.g., prolonged standing) and personal characteristics such as age, length of service, and body mass index (BMI). The objective of the present investigation was to study the effect of working posture on physical fatigue after adjusting for the covariates of age, length of service, and BMI. An analytical cross-sectional study with a quantitative design was applied to 174 Surakarta workers selected by stratified random sampling. Work posture was categorized under standing and sitting, while physical fatigue was measured by the Subjective Self Rating Test (SSRT) questionnaire. ANCOVA via SPSS version 27 software was applied for the analysis, in which age, length of service, and BMI were employed as covariates. The findings indicated that the standing posture was strongly influenced positively on physical fatigue (Partial Eta Squared = 0.547, p < 0.001), and the effect size is large. Significant risk factors were also found to be age (p = 0.012) and BMI (p = 0.035), but the length of service was not significant (p = 0.084). The ANCOVA model also showed excellent predictability values of adjusted R 2 = 0.715, which implied that the model was able to explain 71.5 percent of the physical fatigue. These findings emphasize the importance of posture-based ergonomic interventions to prevent fatigue and improve occupational health in the textile industry
Early Breastfeeding Practices, Energy and Protein Intake, Risk of Stunting in Coastal Areas of Sampang Regency, East Java Province: A Cross-Sectional Study Khomisah, Nuril Alfiatul; Hikmayani, Nur Hafidha; Probandari, Ari Natalia
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.550

Abstract

Stunting remains a significant public health issue in Indonesia, particularly in coastal areas with limited access to nutrition and healthcare services. This study aims to identify early risk factors for stunting in children aged 12–59 months in the coastal areas of Sampang Regency, East Java. The study design employed a cross-sectional approach with a sample size of 250 children, selected randomly in proportion to the population. Data were collected through anthropometric measurements, structured questionnaires, and 24-hour food recalls. Analysis was performed using the chi-square test and simple logistic regression. The results showed a prevalence of stunting of 25,2%. Not getting breast milk in the first two days postpartum (OR=2,447), not getting exclusive breastfeeding for <6 months (OR=2,766), insufficient energy intake (OR=27,695), and insufficient protein intake, which showed the highest risk (OR=192,85), were associated with stunting (p<0,05). In contrast, early initiation of breastfeeding and continued breastfeeding at 12–23 months of age were not significantly associated with stunting. These findings underscore the importance of early nutritional practices and adequate intake of macronutrients, particularly protein, in efforts to prevent stunting. Focused nutritional interventions during the first 1,000 days of life need to be prioritized, including improving maternal education and the quality of children’s food intake.
Nutritional, Physical Activity, and Mental Health Interventions to Enhance Cardiovascular Health: A Scoping Review Elsadai, Elsadai; Trisyani, Yanny; Nuraeni, Aan
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.553

Abstract

Cardiovascular disease (CVD) remains the leading cause of mortality globally and in Indonesia, with rising incidence among younger populations due to modifiable risk factors such as poor diet, physical inactivity, and mental health issues. These lifestyle-related factors are increasingly prevalent, yet interventions addressing them are varied and dispersed across the literature. To explore recent nutritional, physical activity, and mental health interventions for the prevention of cardiovascular disease. This study used a scoping review design. Articles were obtained from six databases, EBSCO-host, CINAHL, PubMed, ScienceDirect, Scopus, Taylor and Francis, and Google Scholar, with the major keywords “dietary”, “physical activity”, “mental health”, “cardiovascular disease”, “prevention”. Inclusion criteria included original studies, in English, published between 2015–2025, and the population reviewed was Adults / General population / High-risk individuals (e.g., aged >30, person with history of CVD). Data extraction followed the PRISMA-ScR guidelines. Twelve articles meeting the inclusion criteria showed intervention of prevention of cardiovascular disease. Physical activities such as walking, yoga, and exercise programs effectively improve cardiovascular health and physical fitness. Nutritional approaches like the Mediterranean diet help reduce cholesterol levels and blood pressure. Mental health practices, including meditation and stress management, contribute to lowering anxiety and blood pressure.  This review emphasizes that integrating regular physical activity, a nutritious diet, and mental health support is essential for effectively preventing cardiovascular disease, with personalized approaches playing a key role in helping individuals maintain these healthy habits.
Proximate and Phytochemical Composition of Bajakah (Spatholobus littoralis Hassk) Extract and its Effect on Fasting Blood Glucose in STZ-HFD-Induced Diabetic Rats Dara, Rizki Wulan; Lisyawati, Shanti; Febrinasari, Ratih Puspita
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.558

Abstract

The rising global prevalence of type 2 diabetes mellitus (T2DM) highlights the urgent need for plant-based therapeutic alternatives. Spatholobus littoralis Hassk, locally known as Bajakah, is a traditional medicinal plant from West Kalimantan, Indonesia, that is widely used by indigenous communities for regulating blood sugar levels. This study aimed to characterize the proximate and phytochemical composition of Bajakah wood extract and evaluate its antidiabetic potential in rats induced with a high-fat diet (HFD) and Streptozotocin (STZ). The extraction was performed using a 70% ethanol maceration method. Proximate analysis revealed low moisture (4.57%), ash (0.54%), total fat (0.81%), and protein (0.41%), with carbohydrates being the most abundant component (6.67%). Phytochemical screening using UV-Vis spectrophotometry identified total phenols (12.98%), flavonoids (1.16%), tannins (1.65%), and saponins (0.13%). The in vivo test on diabetic rats showed that the administration of Bajakah extract at a dose of 150 mg/kg body weight (BW) for 14 days significantly reduced fasting blood glucose levels from 279.46 ± 2.39 mg/dL to 115.62 ± 13.73 mg/dL (P= 0,028), corresponding to a 58,6% reduction. This reduction was greater than that of the positive control group, which was treated with Acarbose. The high content of phenolics and other bioactive compounds is strongly suggested to contribute to the antihyperglycemic effect through antioxidant mechanisms, inhibition of digestive enzymes, and enhancement of insulin sensitivity. This study these findings support the therapeutic potential of Bajakah wood extract from West Kalimantan as a complementary agent for management of T2DM.
The Types of Support That Enhance Body Image in Patients with Breast Cancer: A Scoping Review Christaputri, Silvia Tri Wahyu; Triyanto, Arifin; Tsauroh, Salsabila Fiqrotu; Mulyainuningsih, Wa Ode Saridewi; Effendy, Christantie
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.559

Abstract

Patients with breast cancer often experience dissatisfaction with themselves as a result of the treatment process they undergo, potentially resulting in a negative body image and affecting the effectiveness of treatment and their quality of life. Therefore, support is needed to address this issue. This study aims to identify the types of support that can be provided to improve body image in patients with breast cancer through a scoping review. We conducted a search using five databases, including ScienceDirect, Wiley, Scopus, ClinicalKey, and ProQuest. The inclusion criteria used were English-language articles and original research articles published between January 2020 and May 2025. Review articles, books, and pilot studies were excluded. The screening procedure was conducted in accordance with the PRISMA 2020 guidelines, and article eligibility was assessed by three researchers using the JBI Critical Appraisal Checklist (2020). Ten articles were obtained, indicating that various forms of support can be provided, such as social support (from family, friends, prominent figures, important or special people, and health workers); partner support; psychological support carried out through clinical interventions; and support from groups of fellow breast cancer survivors, but social support from family being the most commonly implemented form. This support helps patients in the process of improving body image that has changed due to the treatment process; however, in practice, the provision of a single type of support cannot stand alone. These findings affirm that providing support to enhance a positive body image in patients requires thorough attention. Further research is expected to explore the effectiveness of each type of support and involve more than one form of support to produce more comprehensive findings.
End-of-Life Acceptance in Hemodialysis Patients: A Conceptual Analysis Wabula, La Rakhmat; Yetti, Krisna; Masfuri, Masfuri; Widyatuti, Widyatuti; Widyawati, Ika Yuni; Septiwi, Cahyu
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.561

Abstract

End-of-life (EOL) acceptance is a crucial but underexplored concept among patients with end-stage renal disease (ESRD) undergoing hemodialysis. This study aimed to analyze and clarify the concept of EOL acceptance in hemodialysis patients using Walker and Avant’s eight-step method. These patients often face progressive physical deterioration and limited life expectancy, making psychological, emotional, and spiritual readiness to confront death a fundamental component of care. However, the term “EOL acceptance” lacks conceptual clarity and consistency in nursing practice. A comprehensive literature review was conducted using PubMed, CINAHL, and Scopus databases, targeting studies published between 2014 and 2024. The keywords used included ‘end-of-life,’ ‘terminal care,’ ‘death acceptance,’ ‘dying acceptance,’ ‘hemodialysis,’ ‘end-stage renal disease,’ and ‘terminal care nursing’. The analysis identified three attributes of EOL acceptance:  psychological readiness to face death, integration of existential and spiritual meaning, and proactive decision-making toward dignified dying. Supporting factors include awareness of terminal illness, therapeutic communication, and psychosocial-spiritual support. The identified consequences are emotional peace, enhanced family preparation, and improved quality of life. This analysis delineates a conceptual framework for EOL acceptance, enabling nurses to assess and support patients facing terminal illness effectively. It also provides a foundational framework for developing assessment tools and nursing interventions to improve person-centered EOL care for individuals with ERSD.
Modulation of GLUT4 and FOXO1 Expression by SH-MSC and Alkaline Water in Experimental Type 2 Diabetes Mellitus Fatmawati, Dian; Putra, Agung; Setiawan, Eko
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.562

Abstract

Type 2 Diabetes Mellitus (T2DM) is a metabolic disorder characterized by insulin resistance, which is associated with the dysregulation of glucose transporter 4 (GLUT4) and forkhead box protein O1 (FOXO1). The secretome from hypoxia-preconditioned mesenchymal stem cells (SH-MSC) and alkaline water have been proposed as potential therapies to modulate these molecular targets and improve glycemic control; however, their combined effects remain unexplored.  Using an experimental post-test-only control group design, this study aimed to assess the possible additive effect of SH-MSC and alkaline water on the expression of GLUT4 and FOXO1 in Wistar rats with type 2 diabetes. Twenty-five male Wistar rats were split into five groups: healthy control (G1), T2DM control (G2), T2DM with metformin (G3), T2DM with SH-MSC (G4), and T2DM with SH-MSC and alkaline water (G5).  Streptozotocin and nicotinamide were utilized to induce T2DM, and qRT-PCR was used to measure the expression of GLUT4 and FOXO1 in pancreatic tissue. One-way ANOVA and a post hoc LSD test were used for statistical analysis. The findings recognized that while GLUT4 expression was decreased, T2DM induction markedly increased fasting blood glucose levels and FOXO1 expression. SH-MSC treatment significantly upregulated GLUT4 and downregulated FOXO1 equated to the control T2DM group, and while the addition of alkaline water showed a further trend of improvement, this difference was not statistically significant. These findings suggest that SH-MSC therapy effectively improves glucose metabolism by modulating GLUT4 and FOXO1 expression, with the potential for alkaline water as an adjunctive therapy in T2DM management
In Vivo Evaluation of Butterfly Pea (Clitoria ternatea) Flower Gel on IL-10 and STAT3 Expression in Thermally Induced Skin Burns Mediana, Mecha Amalia; Hussaana, Atina; Trisnadi, Setyo
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.563

Abstract

Burn injuries caused by thermal exposure trigger oxidative stress and inflammation, largely driven by reactive oxygen species (ROS) and systemic inflammatory response syndrome (SIRS). These mechanisms may disrupt the production of cytokines involved in tissue repair, such as interleukin-10 (IL-10) and signal transducer and activator of transcription 3 (STAT3). Clitoria ternatea L. (butterfly pea) contains potent antioxidant and anti-inflammatory phytochemicals, making it a promising candidate for modulating inflammatory responses and promoting wound healing. This study evaluated the effects of Clitoria ternatea extract gel on IL-10 and STAT3 expression in second-degree burn injuries using a Wistar rat (Rattus norvegicus) model. A post-test only control group design was employed, involving 30 male rats randomly assigned to five groups (G1–G5). Second-degree burns were induced using a 1.8 cm diameter heated metal plate applied to the dorsal skin for 3 seconds after heating for 15 minutes. Treatments with the extract gel were administered topically for seven days. Skin samples were collected 24 hours after the last application and analyzed for IL-10 and STAT3 mRNA expression using qRT-PCR. Data were statistically tested with One-Way ANOVA. The results showed no significant differences in IL-10 expression among all groups. However, STAT3 expression was significantly higher in the groups treated with 5% and 10% Clitoria ternatea extract gel, with the highest observed in the 10% group (6.73 ± 2.94). These findings indicate that while IL-10 remained unaffected, butterfly pea extract gel effectively increased STAT3 expression, suggesting its potential role in modulating regenerative pathways in burn-injured skin

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