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Journal of Pharmaceutical and Sciences.
Published by Universitas Tjut Nyak Dhien
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 654 Documents
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Uji toksisitas buah palem merah (Cyrtostachys renda Blume.) menggunakan metode brine shrimp lethality test (BSLT) method Syamsurizal, Syamsurizal; Utami, Diah Tri; Sutrisno, Sutrisno; Efrini, Emi; Jumardi, Muhammad Ikhsan
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.429

Abstract

The red palm plant (Cyrtostachys renda) is a species of the Areca genus that grows widely in Jambi Province, making it an affordable plant to research for its medicinal properties. The Brine Shrimp Lethality Test (BSLT) is a toxicity test to screen for anticancer bioactive substances, with the test subject being Artemia salina Leach larvae, which are highly sensitive when exposed to toxic substances. The fruit and roots of C. renda were extracted using the maceration method by using a methanol solvent and partitioning using n-hexane, dichloromethane, ethyl acetate, and water. Based on the extract toxicity evaluation results, all extracts were toxic. Meanwhile, C.renda root dichloromethane extract had the highest toxic properties, with an LC50 value of 43.42 ± 0.659 ppm. However, the positive control's toxicity, potassium dichromate, was more toxic, with an LC50 value of 29.93 ± 0.668 ppm. The dichloromethane extract of C. renda roots can potentially be a poisonous agent. Further toxicity tests on cancer cells need to be carried out to be developed as an anticancer agent.
Pemanfaatan daun kelor (Moringa Leifra) dalam fortifikasi pembuatan nugget Matondang , Syaiful Nasri; Asmaq, Nur
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.433

Abstract

The aim of this research was to determine the quality of chicken nuggets by adding moringa leaf flour (Moringa leifra) in the manufacturing process. The materials used in this research were broiler chicken meat, Moringa leaf flour, wheat flour, bread flour, eggs, tapioca flour, shallots, garlic, oil, pepper, salt and other kitchen spices. The method used in this research was an experimental method with a completely randomized non-factorial design with 4 treatments and 4 replications. The parameters tested were Antioxidants, Cholesterol, and Total Bacterial Colonies. The treatments in this study were P0 (without the addition of Moringa leaves); P1 (addition of 5% Moringa leaf flour); P2 (addition of 10% Moringa leaf flour), P3 (Addition of 15% Moringa leaf flour). The results of this study showed that the addition of Moringa leaf flour in making chicken nuggets had a very significant effect (P<0.01) on antioxidant and cholesterol levels.
Aktivitas antioksidan dan uji toksisitas ekstrak kulit batang kayu raru (Cotylelobium lanceolatum Craib) dengan menggunkan metode DPPH dan metode BSLT Rossa, Aliffa; Daulay, Anny Sartika; Ridwanto, Ridwanto; Rahayu, Yayuk Putri
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.436

Abstract

Raru (Corylelobium lanceolatum Craib) is a group of endemic tropical forest plants from the Dipterocarpaceae family in Indonesia. Raru is a term for a group of types of bark added to palm sap, which aims to increase the taste and alcohol content of the drink. People in Sumatra believe that raru bark (Cotylelobium lanceolatum Craib) can be used as an antidiabetic drug. This study aims to determine the antioxidant activity of raru bark, the toxicity activity of raru bark extract, and the secondary metabolites in raru bark. This research was conducted in descriptive was born with a descriptive method. The sample used was raru bark. The research phase included sample preparation, plant identification, simplicial manufacture, antioxidant activity test, DPPH standard stock preparation, blank solution preparation, phytochemical screening, antioxidant activity test based on IC50, Toxicity test, and toxicity activity test based on LC50 value. The result obtained in testing the antioxidant activity of raru bark had an IC50 value of 94.25 µg/mL in the vary strong category. While the result of the probit analysis for the toxicity of raru bark extract using the BSLT method obtained an LC50 value of 350.9942 µg/mL. It is in the toxic category and has the potential to be an anticancer.
Analisis potensi interaksi antar obat pada resep polifarmasi di apotek kota Bandung Aulia, Nazela Constantia Hilyatul; Subarnas, Anas
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.443

Abstract

Problems that can occur in drug prescribing patterns are Drug Related Problems (DRP), which can affect the patient's clinical condition. One type of DRP that often occurs is drug interactions. Drug interactions cause changes in the effect of a drug due to the presence of other drugs taken simultaneously, which will cause a decrease in the therapeutic effect of the drug and increase toxicity in the body. Therefore, drug interactions were identified from general practitioner prescriptions at one of the Bandung City pharmacies. General practitioner prescription data was taken from July-September 2023 at the pharmacy in Bandung City, namely 202 prescriptions, and categorized based on their severity using the website drug, com. The results of this identification showed that 32 prescriptions had interactions between drugs with different levels of severity, showing that 2 prescriptions (6%) had drug interactions of different types. In the majority, 24 prescriptions (75%) had moderate drug-type interactions, and 6 recipes (19%) had minor.
Peran apoteker dalam menangani swamedikasi kasus minor illnes di apotek Burhanudin, Yasmin Ramadania; Gozali , Dolih
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.445

Abstract

Health is a crucial part of life. An individual's level of living is reflected in their state of health. The most important thing to do if the person has health issues at any point is to make every effort to heal through self-medication. Preparing this article is to evaluate how healthy pharmacists perform self-medication and make drug selections to enhance public health. Self-medication is typically used to cure common minor health issues, such as skin infections, worm infections, coughs, influenza, stomach ulcers, dizziness, coughing, diarrhea, and coughing up blood. The research in question was derived from search engine results and examined pharmacists' capacity to prescribe medications for mild ailments. According to the search results in several journals, the overall accuracy rate of recommendations for children experiencing acute diarrhea is 13.09%; for diarrhea, including blood, it is 34.52%; for dyspepsia due to side effects of Diclofenac Sodium, it is 21%; and for dyspepsia without alarm, symptoms is 83%. According to research findings, enhancing pharmacists' capacity to offer drug guidance while facilitating self-medication is crucial.
Analisa Kromatografi Gas Spektrometri Massa dan Gugus Fungsi Ekstrak Metanol Daun Bidara (Ziziphus mauritiana): Analisa Kromatografi Gas Spektrometri Massa dan Gugus Fungsi Ekstrak Metanol Daun Bidara (Ziziphus mauritiana) Widiarti, Leni; Febriani, Husnarika; Dur, Sajaratud; Ningrum, Nurlian Augustin; Nurcahyani, Nadya; Andry, Muhammad
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.449

Abstract

Bidara leaves are a plant that is quite abundant in Medan and has many benefits in the health sector. The aim of this research is to predict the content of secondary metabolite compounds in bidara leaf extract, through qualitative tests by screening using specific reagents, functional group analysis with FT-IR and mass analysis with GC-MS. The screening results showed that the methanol extract of bidara leaves contained alkaloids, flavonoids, tannins, saponins and phenols. Functional group analysis shows that the wavelength area is 3300 cm-1, namely OH absorption, 2700 - 2900 cm-1 shows C-H absorption, 1600 - 1700 cm-1 shows C=O absorption, 1400 - 1450 cm-1 shows C-H absorption, 1365 - 1385 cm-1 shows CH3 bent absorption, and 1000 – 1100 cm-1 shows C-O absorption. The results of mass analysis using GC-MS showed four dominant peaks from the compound, namely Z-5-Methyl-6-heneicosen-11-one, 17-Pentatriacontene, Ethyl iso-allocholate and Pentacosane.
Uji aktivitas antioksidan ekstrak etanol, etil asetat, dan n-heksan akar kayu manis hutan (Cinnamomum Iners) Reinw. EX Nees & T. Nees Blume dengan Metode DPPH Faisal , Hendri; Andry, Muhammad; Winata, Hanafis Sastra; Panjaitan, Yuli Cahyani
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.450

Abstract

Background: Forest cinnamon (Cinnamomum iners) Reinw. Ex Ness & T. Ness Blume has been used traditionally to kill microorganisms, diarrhea and dismonere. Forest cinnamon contains compounds that act as antioxidants, including flavonoids, alkaloids, tannins, and phenolics. The antioxidant effects of vitamin C, E, carotene, and phenolic compounds (especially polyphenols and flavonoids) can potentially reduce the risk of degenerative diseases. Objective: compounds from forest cinnamon roots and determine the yield based on the level of polarity to DPPH with the IC50 value. Method; eksperimental di laboratorium yaitu melakukan percobaan terhadap aktivitas antioksidan dari ekstrak akar kayu manis hutan (Cinnamomum Iners) dengan Metode DPPH (1,1- difenil -2 pikrihidrazil). Penelitian meliputi pengumpulan akar kayu manis hutan, pembuatan ekstrak akar kayu manis hutan, uji skrining fitokimia terhadap akar kayu manis hutan, dan uji antioksidan dari ekstrak akar kayu manis hutan dengan Metode penangkalan radikal bebas DPPH (1,1-difenil –2 pikrihidrazil) menggunakan alat spektrofotometer. Results: The antioxidant activity of the ethanol solvent showed a very strong category, the ethyl acetate solvent showed medium category activity, and the n-hexane solvent showed weak category antioxidant activity. The average IC50 value of ethanol extract was 9.1 ppm, ethyl acetate extract was 77.58 ppm, and n-hexane extract was 185.08. Conclusion: forest cinnamon root (Cinnamomum Iners) Reinw. Ex Ness & T. Ness Blume has strong antioxidant activity in ethanol solvents.
Uji aktivitas antioksidan ekstrak etanol dan sari kulit nanas (Ananas comosus (L) Merr) menggunakan metode radical scavenger Nadia, Syarifah; Julianty, Siti Muliani; Tambunan, Ika Julianti; Fujiko, Muflihah
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.455

Abstract

Inheritance, Indonesian society has been utilizing various plants as traditional medicine for preventive measures and treatment of various diseases. The pineapple plant or (Ananas comosus (L) Merr) is one of the plants that is often used for treatment. Pineapple (Ananas comosus (L) Merr) contains flavonoids and phenolics, which are productive as natural antioxidants. This research was carried out using experimental methods. The research included collecting materials followed by plant identification, phytochemical screening, making ethanol extract from pineapple peel, and testing antioxidant activity using the radical scavenger method using a Visible Spectrophotometer. The results of research on pineapple rind Simplicia (Ananas comosus (L) Merr), ethanol extract, and water juice of nans rind contain chemical compounds of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids and glycosides. Ethanol extract and water juice from pineapple peel have antioxidant activity, which was tested using the radical scavenger method against DPPH (1,1-diphenyl-2-picryhydrazyn) solution. Ethanol extract and water juice from pineapple peel have antioxidant activity, but unlike vitamin C, the antioxidant is categorized as very strong. Meanwhile, the ethanol extract of pineapple peel is categorized as strong, and the water extract of pineapple peel is categorized as medium.
Formulasi body scrub dari kombinasi temu putih (Curcuma zedoaria) dan biji kurma (Phoenix dactylifera) Yuliawati, Yuliawati; Elisma, Elisma; Utami, Diah Tri; Pratiwi, Puspa Dwi
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.456

Abstract

Body scrub is a cosmetic form that removes dead skin cells caused by free radicals from various pollutants and ultraviolet (UV) radiation so skin cells become more accessible to regenerate. White turmeric (Curcuma zedoaria) and date seeds (Phoenix dactylifera) are plants that contain bioactive compounds to maintain and nourish the skin and have antioxidant activity. Besides, date seeds also have the potential as exfoliating agents to facilitate the release of dead skin cells. This study aimed to formulate a body scrub containing ethanol extract of white turmeric rhizome and date seed powder with five types of formulas (K+, K-, F1, F2, F3). This type of research is a true experimental, which includes the formulation and stability test. The stability test was conducted with the Cycling test method in 6 cycles (1 cycle for 2x24 hours) at temperatures of -4oC and 40oC and four months for stability at room temperature. Parameters observed include organolepticity, homogeneity, dispersibility, adhesion, pH, and viscosity. The results showed that this body scrub did not show any change in the organoleptic character, homogeneity, spreadability, adhesion, or pH values that met the requirements of a body scrub preparation. Viscosity met the requirement for stability test for room temperature in four months. This study concludes that the combination of ethanol extract of white turmeric rhizome and date seed powder seeds can be formulated to be a body scrub dosage form.
Analysis of drug management in Pharmacy Installations Colonel Abunjani Bangko Regional General Hospital Maimum, Maimum
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.457

Abstract

Pharmaceutical care in the hospital is one activity that can support good quality. According to the previous observation, in some cases, the adding number of drugs, choosing a less precise drug, emptiness of the drug, and inexpediency between drug planning and consumption. Considering the importance of drug management, then it needs to be browsed all phases of drug management, from the beginning step of selection, procurement (planning and supplying), storage, distribution, and use. The study used descriptive analysis by taking prospective and retrospective data. Data related to drug management is analyzed to use indicator management of drugs. Then, the result is compared with existing standards and research done in another hospital. The results of the interview are also supported by further analysis. Study results indicate that the selection phase has not yet shown efficiency at indicator according to drug with DOEN and formularium. Phase of planning: did not make the drug requirement; on the other hand, the fund allocation is enough to make it. The phase of supplying: The frequency of providing drugs is low, and 15 35% of invoices do not match an order then, and delayed payment is 22 days on average. Storage and distribution show good results. The phase of use, the percentage of drugs prescribed by generic name for hospitalized and ongoing patients 27,1% and 32,3%, the rate of medicines prescribed from formulary for hospitalized 87, 78% and persistent patients 89,95%, percentage usage of antibiotics for hospitalized 12, 57% and 24, 82% for the ongoing patient, percentage usage of injection for hospitalized 47, 26%, the average number of drug per encounter 2, 9 for hospitalization and ongoing patient.

Page 30 of 66 | Total Record : 654

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