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Journal of Pharmaceutical and Sciences.
Published by Universitas Tjut Nyak Dhien
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 654 Documents
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Hubungan komunikasi efektif petugas pendaftaran rawat jalan dengan kepuasan pasien di rumah sakit Advent Medan Rangkuti, Dyna Safitri Rakhelmi; Tarigan, Andini Mentari; Rachelia , Panjaitan Hanyita
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.358

Abstract

Effective communication is conveying thoughts or information from one person to another so that others grasp what the information provider means. Effective communication is required while working with patients; if it is not used effectively, it will disrupt the connection, resulting in patient discontent. This study aimed to investigate the effectiveness of outpatient registration officers' communication associated with patient satisfaction at Advent Hospital Medan 2023. The research method was quantitative, using a cross-sectional approach. The population consisted of all outpatients registered at the Outpatient Patient Registration, including 28,963 respondents. Purposive sampling was utilized in this investigation, with a total sample of 100 respondents. The Chi-Square test used univariate and bivariate data analyses. The results showed that the respect variable had a p-value value of 0,000 <0.05, the empathy variable had a p-value value of 0,000 <0,05, the audible variable had a p-value value of 0.000 <0.05, the clarity variable had a p-value value 0,000 <0.05 and the Humble variable has a P-value value of 0,000 <0.05. According to the findings of this study, respect, empathy, audibility, lucidity, and humble outpatient registration officers are associated with patient happiness. The registration officer advised to develop effective contact with patients to promote patient satisfaction with health services.
Review artikel: Pemanfaatan jaminan kesehatan ibu dan anak dalam pelayanan persalinan di puskesmas kabupaten atau kota di Indonesia Salman, Salman; Hilmi, Indah Laily; Oktavianti, Alfina; Salsabila, Isyana; Lestari, Sepiyani Ayu; Putria, Devy Kasih; Windari, Welly
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.360

Abstract

Universal Health Coverage (UHC) is one of the government's targets in public health services to the Sustainable Development Goals (SDGs). The UHC is a crucial and urgent resolution for all nations to expand health systems with equal access and affordable costs. The program is one of the efforts to lower the maternal and infant mortality rate. As a healthcare provider, public health centers must ensure optimal care and services. Public health centers realize that providing health care refers to the core health efforts program. This research aims to analyze maternal and child health insurance use in maternity services in Public health centers. The analysis uses the study methodology of the literature review library with search engines used in literature searches such as Google Scholar and PubMed with the keywords Birth Assurance, Public Health Centers, Sustainable Development Goals, and Universal Health Coverage. The survey results show that the use of maternity guarantees for the population in Public health centers in terms of efficiency, effectiveness, responsiveness, uniformity, and accuracy still needs to be better achieved. The research identifies differences between people's expectations of quality of health care and the realities experienced, focusing on the various dimensions that make up quality of service. These dimensions include reliability, responsiveness, assurance, empathy, and tangible. The conclusion of this study suggests that services in Public health centers should be continuously improved through capacity improvements, improvements or renovations of infrastructure and systems, as well as some programs with preventive, promotional, and empowerment of the public to UHC.  
Anatomical Therapeutic Chemical / Define Daily Dose antibiotik bronkopneumonia pediatri di RS Roemani Muhammadiyah Maharani Dewi, Rissa; Maprillia , Nanda; Nastiti , Nindita Sari
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.373

Abstract

The increase in repeat hospitalizations after the covid19 pandemic with bronchopneumonia diagnoses in pediatric patients is the first rank. Therapeutic management was associated with the length of hospitalization. Pediatric bronchopneumonia is the case with antibiotic therapy. Current guidelines recommend first-line and alternative options in the management of antibiotic therapy for pneumonia in hospitalized pediatric patients. Empirical broad-spectrum antibiotic therapy for acute infections with consideration of the common etiology of possible pneumococcal involvement The risk of resistance increases with the massive use of antibiotics. The study had an observational descriptive design with retrospective data collection from 280 samples of pediatric patients, aiming to evaluate the use of antibiotics with the ATC/DDD method. Based on empirical selected therapy DDD (Define Daily Dose)/100 patient days, the quantity of antibiotics that are widely used is ceftriaxon 38.36 DDD /100 patient days followed by Cefoperazon sulbactam 3.88 DDD /100 patient days, Cefotaxime 3.77 DDD /100 patient days, Gentamicin 2.57 DDD /100 patient days, Amikacin 1. 70 DDD /100 patient days, Azithromycin 0.76 DDD /100 patient days, Ampicillin Sulbactam 0.50 DDD /100 patient days, Cefixime 0.27 DDD /100 patient days, and Meropenem 0.13 DDD /100 patient days. Drug data included in DU90% are Ceftriaxon, Cefoperzon Sulbactam, Cefotaxime. From the research conducted, the highest DDD/100 patient days value was Ceftriaxon. DDD value indicates high use of antibiotics, does not mean unreasonable use of drugs, so a qualitative review must be done.
Gambaran pemeriksaan tubex dan widal pada pasien suspek tifoid di RSUP. H. Adam Malik Medan tahun 2023 Ginting, Radina Yuni Mahesa; Purba, Sanna Kamisna Royani
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.380

Abstract

Typhoid fever is a disease that attacks the human digestive tract, and it is very closely related to environmental sanitation factors. This disease occurs in Asian countries, namely Indonesia. This disease can spread through contaminated food and drink caused by Salmonella enterica serovar typhi (S.Typhi) and is an infectious disease. Typhoid fever is an infectious disease caused by Salmonella typhi bacteria; it occurs through food and drink, which causes disease spread by food and drink; the germs will continue to grow and spread into the intestinal tract; symptoms include prolonged high fever, fatigue, headaches, nausea, and pain. Stomach, and constipation or diarrhoea. Some patients will experience changes to have a rash; severe cases can cause serious complications or even death. Typhoid fever can be seen through the blood. The design used in this research was quantitative descriptive with a cross-sectional approach. To determine Salmonella typhi bacteria in samples of typhoid fever patients at RSUP.H. Adam Malik. Of the 69 respondents who underwent the Tubex examination, 34 (49.3%) and Widal 35 (50.7%).
Analisis penggunaan antidiabetik dan antihipertensi pada pasien diabetes komorbid hipertensi di Puskesmas Mrebet Melani, Reina; Kurniasih, Khamdiyah Indah; Fauziah, Fauziah
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.382

Abstract

Diabetes Mellitus (DM) is a chronic disease characterised by high blood sugar levels. Diabetes mellitus is considered the "mother disease" because it is the mother of various diseases such as hypertension, heart disease, stroke, kidney failure and blindness. There were 13,117 DM cases in Purbalingga Regency, and 14,035 people were provided services according to procedures. Increased blood glucose levels (hyperglycemia) cause intravascular fluid resistance, which results in an increase in body fluid volume and an increase in peripheral arterial resistance. These two conditions are the basis for hypertension. There is a need for appropriate antidiabetic therapy to treat hypertension comorbid DM disorders. This research was conducted at the Mrebet Community Health Center, Purbalingga Regency, where the results obtained were 55 data on the use of prolanis medication for DM comorbid hypertension patients. In this study, the most common single therapy was metformin (12.7%), then the two most common combinations were glimepiride and acarbose (41.8%), while the three combinations used were metformin, glimepiride and acarbose (12.7%). The most common single antihypertensive was Lisinopril (28.2%), and the most common combination was Lisinopril + Amlodipine (28.2%).
Evaluasi in vitro dan in silico aktivitas toksikologi dan anti proliferasi senyawa fitokimia beberapa ekstrak pelarut dari Zaleya Pentandra L Elsamani, Mohamed O.
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.404

Abstract

Therapeutic plants and herbals are vital superior nutrient resources mainly used in diet and recognised for treating various diseases. The study's main objective is to investigate phytochemicals compounds, antioxidant and antibacterial activities on five Zaleya pentandra extract (ZPE), ethanol, hexane, acetone, ethyl acetate, and methanol for the first time.  Methods: The study was conducted using the HPLC-MS, and measurements were made in three replicates.  Results: The most significant extracts, revealing 13compounds, which appear higher content (417.5±0.44 μg/g and (407.5±0.04 μg/g), value of ZPE in total β-Sitosterol and dioctyl phthalate, respectively, also the total polyphenol content (TPC) was significantly (p≤0.05) higher mainly in acetone (323.06±1.74mg GAE/g), ethyl acetate (220 ± 1.00) mg GAE/g), and hexane herbal extracts (75.2±1.70) mg QE/g) with a significant difference (P≤0.05) in total flavonoid content. Discussion: All investigated bacterial strains had an exceptionally high effect against B. subtilis. A computational analysis qualified a significant drug-likeness feature, including toxicological and pharmacokinetic assessments. ZP acetone extract is an appropriate selection for creating contemporary antibacterial compounds. Conclusions: The current study offers new information on applying ZPE in novel and potentially effective therapeutic agents, its application in the food industry, and the treatment of different diseases.
Analisis literasi kesehatan pasien diabetes melitus tipe 2 dengan terapi oral antidiabetes di puskesmas Surabaya Vidiani , Anak Agung Pradnya Paramitha; Puspitaningrum, Anisa Nova
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.413

Abstract

Introduction: Diabetes mellitus (DM) is a chronic disease requiring long-term therapy. Uncontrolled glucose levels can lead to micro and macrovascular complications as well as therapy failure. Medication adherence is a factor influencing the success of DM therapy. The aim of this study is to understand the adherence to oral antidiabetic drugs (OAD). Methods: This research employs a quantitative approach with a non-experimental cross-sectional design. The sample consists of all type 2 DM patients using OAD therapy at Surabaya Community Health Centers who meet the inclusion and exclusion criteria. Results and Conclusion: The health literacy level of Type 2 Diabetes Mellitus Referral Program patients who received Oral Anti-Diabetes therapy at the Surabaya Community Health Center in this study was 45% with high health literacy and 55% with low health literacy with a percentage of 55%. With the domains of patient attitudes towards health (72.50%), patient understanding of health information (57.50%), social support (22.50%), socio-economic considerations (75.00%), accessing health services (92.50%), 50%), communication with health workers (77.50%), pro-active (17.50%), and using health information (80.00%)
Hubungan stres kerja tenaga kesehatan dengan kualitas pelayanan di UPT Puskesmas Medan Sunggal Fitria, Dilla; Salmira, Cut Saura; Meliala, Sri Agustina
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.414

Abstract

Introduction: The quality of healthcare services hospital staff provides is essential for advancing a hospital as a healthcare service provider. Work-related stress experienced by healthcare workers due to heavy workloads can impact patient care quality. This study examines the relationship between work-related stress among healthcare workers and service quality at UPT Puskesmas Medan Sunggal in 2023. Method: This study employs a quantitative research design with a cross-sectional approach. The population consists of 50 respondents, and a total sampling technique was applied, resulting in a sample size of 50 respondents. Data analysis includes univariate and bivariate analyses. Results: The chi-square statistical test revealed a significant relationship between work-related stress and service quality, with a p-value of 0.006 < α (0.05). This indicates a significant correlation between healthcare workers' stress levels and the quality of services at UPT Puskesmas Medan Sunggal in 2023. Conclusion: There is an important relationship between healthcare workers' stress levels and service quality at UPT Puskesmas Medan Sunggal. Most healthcare workers experience moderate stress (52%), while 66% of respondents express dissatisfaction with the services. The chi-square test confirms a significant association between these variables (p-value 0.006 < 0.05), highlighting the need for effective stress management strategies to improve service quality.
Hubungan status gizi dengan kejadian penularan tuberkulosis dalam keluarga di Desa Batusumur Kecamatan Manonjaya Kabupaten Tasikmalaya Dewi, Candrawati Puspita; Raharjo, Mursid; Adi, Mateus Sakundarno
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.422

Abstract

Tuberculosis is the second infectious disease that causes the most deaths in the world according to WHO. Indonesia is a high TB burden country which currently ranks third in the world, with an incidence of 845.000 or 320/100.000 population with a mortality rate of 98.000 or 40/100.000 population and 3,6/100.000 TB-HIV population. The risk factor that can cause tuberculosis disease is malnutrition. The aim of the study was to determine the relationship between nutritional status and the incidence of tuberculosis transmission in the family. The purpose of this study was to determine the relationship between nutritional status and the incidence of tuberculosis. The research design used cross sectional study. The research was conducted in December 2023 in Batusumur Village, Manonjaya District, Tasikmalaya Regency. The research sample was 39 respondents of tuberculosis patients. Inclusion criteria: patients actively communicate and are easy to talk to, patients live with family members and are still in the initial phase of treatment in the first 2 months. The independent variable was nutritional status. The dependent variable was the incidence of pulmonary tuberculosis transmission in family members. The instrument was an observation sheet. Data were analyzed by chi square test using SPSS. This research applies the principles of confidentiality, useful information and scientific development. The results showed that there was a relationship between nutritional status (p=0,026) and the incidence of tuberculosis transmission in the family. The conclusion is that there is a relationship between nutritional status and the incidence of tuberculosis. Tuberculosis patients and their families can make preventive efforts to prevent tuberculosis transmission.
Gambaran gaya hidup penderita hipertensi di puskesmas Pamolokan Kecamatan Kota Sumenep Kabupaten Sumenep tahun 2023 Ulfa, Nadiyah; Purbowo Sintoro, Henry; Wibowo, Prajogo; Pratama A., Ronald
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.426

Abstract

Hypertension, a widespread global health issue, significantly contributes to the burden of non-communicable diseases. Its escalating prevalence globally and in Indonesia necessitates a comprehensive understanding of associated lifestyle patterns. This study, conducted at Pamolokan Health Center in Sumenep City District, Sumenep Regency, in 2023, focuses on the lifestyles of hypertensive patients. Globally, hypertension affects a substantial portion of the population, impacting public health significantly. In Indonesia, the prevalence of hypertension has steadily risen, prompting a focused examination of contributing factors. Among 85 hypertensive respondents, those aged 36-45 comprised 74.12%, with females constituting 76.67%. Hypertension severity varied, with 55.29% experiencing grade 1 hypertension. The study assessed lifestyle components, revealing 23.53% smoking, 67.06% favouring salty foods, 52.94% consuming fatty foods, 58.82% indulging in coffee, and 35.29% reporting regular physical activity. Understanding the lifestyle patterns of hypertensive patients is crucial for devising targeted interventions. This study's findings illuminate the interplay between age, gender, hypertension severity, and lifestyle choices. Insights contribute to the hypertension management and prevention discourse, emphasising the imperative of tailored public health strategies to address this global health challenge.

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