cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Windadari Murni Hartini
Contact Email
garuda@apji.org
Phone
+6288215137076
Journal Mail Official
bagusharinugroho@arikesi.or.id
Editorial Address
Perum Cluster G11 Nomor 17 Jl. Plamongan Indah, Kadungwringin, Pedurungan, Semarang, Provinsi Jawa Tengah, 50195
Location
Kota semarang,
Jawa tengah
INDONESIA
Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 367 Documents
 33   34   35   36   37 
Diagnosis dan Tatalaksana Epistaksis: Tinjauan Literatur Terkini Putri Alvina Sofia Adila Nafsih; Cut Elvira Novita
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2014

Abstract

Epistaxis, or more commonly known as nosebleeds, is one of the most frequently encountered medical emergencies in the field of ENT. Epistaxis is a condition in which blood flows from the nasal cavity. Although often considered a minor disorder, epistaxis can be a sign of a more serious medical condition, especially if it occurs repeatedly or in large amounts. Globally, the prevalence of epistaxis is estimated to be around 21.7%, with a wide range of variation between countries, namely between 3 and 60 cases per 100,000 population per year. This paper aims to review the aspects of diagnosis and management of epistaxis based on the latest literature. The method used in this study was a search and analysis of various scientific publications, guidelines, and relevant current journals. The discussion covers the identification of types and signs of epistaxis, emergency management, and tampon insertion strategies. Understanding the appropriate and rapid diagnosis and management is essential to prevent the condition from worsening.
Evaluasi Aktivitas Farmakologi Simplisia Kopi Arabika (Coffea arabica) pada Berbagai Konsentrasi terhadap Sistem Saraf Otonom dan Sistem Saraf Pusat Anggun Aldiansa; Ilmi Nurashiilah; Nahla Aulia Azis; Nasifa Kayla Putri; Andi Tenriani Awaliyah; Ayu Azkiya; Aulya Nurul Imama R; Hilda Kadir; Muhammad Chairul Anam; Andi Utari Prasetya Ningrum
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2015

Abstract

Arabica coffee (Coffea arabica) contains various bioactive compounds such as caffeine, polyphenols, flavonoids, and alkaloids that have the potential to produce diverse pharmacological effects on both the autonomic and central nervous systems. The variation in its chemical composition is influenced by factors such as cultivar, post-harvest processing, and preparation methods, resulting in biological responses that are dose-dependent and not always linear. This study aimed to evaluate the pharmacological activity of arabica coffee simplicia powder at three concentrations (1%, 2%, and 4%) by observing parasympathomimetic, parasympatholytic, sympathomimetic, sympatholytic, analeptic, central nervous system stimulation and depression, as well as muscle relaxation parameters. The research was conducted using a laboratory experimental design with test animals administered orally according to the designated concentrations. The results showed that some parameters increased at higher concentrations, such as parasympathomimetic activity (51.85%) and central nervous system stimulation (63.74%), while other parameters demonstrated decreasing or biphasic patterns, such as sympatholytic activity, which was high at 1% and 4% but low at 2%, and analeptic activity, which dropped sharply at 2% and increased again at 4%. These response patterns align with literature indicating that caffeine and polyphenols such as chlorogenic acid may interact synergistically or antagonistically, generating complex pharmacological effects through mechanisms involving adenosine modulation, excitatory neurotransmitters, the enteric nervous system, as well as antioxidant and anti-inflammatory pathways. Overall, this study demonstrates that arabica coffee simplicia exhibits multipotential pharmacological activity, with responses strongly influenced by concentration and the composition of its bioactive compounds, thereby providing a basis for further research on the phytopharmaceutical potential of arabica coffee.
Artikel Review : Efektivitas dan Keamanan Berbagai Rute Pemberian Obat Injeksi Suspensi Dila Alvia Rahmasari; Maulina Apriani; Amina Syifa; Dewi Febiyanti; Nurul Islami Ningtiyas; Nabilla Navyani Putry A; Dewi Rahmawati; Dzakiya Zhihrotulwida; M.Fithrul Mubarok
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2036

Abstract

Advances in technology and research in the field of pharmacy have driven innovation in drug formulation and administration methods to improve the effectiveness and safety of therapy. One of the most widely developed dosage forms is suspension injections, which are sterile preparations containing particles of active ingredients that are insoluble in the carrier fluid. This study aims to review the effects of various administration routes, such as intra-articular, intramuscular, and subcutaneous, on the efficacy and safety of suspension injections. The method used is a literature study analyzing various scientific journals from databases published in the last ten years. The results of the review show that the route of administration has a significant effect on the therapeutic effect, where the intra-articular route provides a strong local effect with low systemic risk, the intramuscular route produces long-term effects and is relatively easy to perform, while the subcutaneous route provides stable drug release over a long period of time. Overall, the choice of injection route for suspension injections should be tailored to the characteristics of the drug, the patient's condition, and the therapeutic goals to achieve optimal, safe, and comfortable treatment outcomes for the patient.
Asuhan Kebidanan Berkesinambungan Ny.C 32Th di PMB Nur Ika Rahayu Kota Batam Farah Zahidah Imtinan; Siti Husaidah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2038

Abstract

The goal of continuous midwifery care is to use the SOAP documentation technique to provide comprehensive care to pregnant women up to birth control according to care standards. From May 2 - July 14, 2025, Mrs.C, G2P1A0, 32 years old received continuous midwifery care from pregnancy until get contraception methods, starting at 34 weeks of gestation. The mother complained of back pain during prenatal check-ups. The labor process went smoothly. With the assistance of a midwife, the baby was born on June 10, 2025. Birth weight: 3000 grams; length: 50 cm; head circumference: 34 cm; chest circumference: 33 cm; received Hb0 vaccine two hours after birth, eye ointment, and vitamin K shortly thereafter. The baby did not experience any problems or complaints during the first visit. Mrs. C received four visits during the postpartum period. The mother did not feel anything during the first visit up to the following visits. She continued to breastfeed exclusively, and her vital signs and fundal height returned to normal. The mother used a three-month injectable contraceptive so as not to interfere with the exclusive breastfeeding program. Mrs.C has received continuous midwifery care during pregnancy and contraceptive use, and her health is normal. It is expected that the midwife will be able to provide continuous midwifery care so that in the event of an emergency, it can be immediately identified and promptly handled.
Penggunaan Madu dalam Sediaan Topikal sebagai Pelembap Kulit Ni Kadek Lidia Ayu Aristina; I Gede Made Suradnyana; Ni Made Sukma Sanjiwani
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2044

Abstract

Skin is the body's outermost organ, enveloping all parts of the human body. When the water content in the stratum corneum (SC) drops below 10%, the skin can become scaly, rough, and dry. Honey possesses humectant, emollient, and antioxidant properties, making it an effective moisturizer. The humectant properties of honey stem from its high sugar content, particularly glucose and fructose. These  sugars form hydrogen bonds with water, helping to retain moisture in the skin and thus providing a hydrating effect. Additionally, honey contains vitamin C, alpha hydroxy acids, and flavonoids, which contribute to the elasticity and firmness of the skin. Therefore, it is important to conduct a narrative review on the use of honey as a moisturizer in topical preparations, which can serve as a reference for future research. The literature search for this review was conducted using databases such as Google Scholar, Garuda Journal, MDPI, ResearchGate, and Publish or Perish, employing specific inclusion and exclusion criteria. The findings concluded that honey can be used as a moisturizer in various dosage forms, including body scrubs, anti-aging and moisturizing creams, serums, peel-off gel masks, lip moisturizers, and lip scrubs. The concentration of honey used in these formulations depends on the dosage form, its intended function in the formula (whether as an active substance, humectant, or emollient), and the comparison of honey concentration with other ingredients.
Pemetaan Riset Global Senyawa Fenolik dan Flavonoid dalam Sediaan Dekok (2015-2025): Analisis Bibliometrik dari Etnobotani dan Potensi Antioksidan Dwi Endah Kusumawati; Davia Maulidda Suharno
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2052

Abstract

Decoction is a traditional extraction method rooted in ethnobotany; however, meeting quality standards in modern pharmaceutical research remains a major challenge. This study aims to map global research trends regarding phenolic and flavonoid compounds in decoctions over the 2015–2025 period through bibliometric analysis. Data were retrieved from the Scopus database and analyzed using VOSviewer 1.6.20 software, employing the fractional counting method to ensure a more proportional weighting of keyword relationships. The results indicate a fluctuating trend that significantly increased toward the end of the period, peaking at 78 documents in 2025, with India and China emerging as the primary contributors. Network visualization and research density analysis reveal that the global research focus remains centered on antioxidant capacity (DPPH, TPC, and TFC), while decoction itself occupies a supporting position within the research map. This study concludes that decoction has not yet become a central focus in modern pharmaceutical research but serves primarily as a vehicle for presenting active compounds. There remains a significant gap between traditional decoction use and the application of advanced analytical technologies such as HPLC and antibacterial testing, representing a substantial opportunity for future research to validate the safety and efficacy of decoctions more scientifically and through standardized approaches.
Hubungan Kepatuhan Minum Obat dengan Tekanan Darah pada Pasien Hipertensi: Literatur Review Tasya Aprilia Pubioganda; Oktafany Oktafany; Citra Yuliyanda Pardilawati
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2053

Abstract

Hypertension is a chronic condition that requires long-term management due to its strong association with an increased risk of serious complications when blood pressure is not adequately controlled. One of the key factors influencing the success of hypertension management is patient adherence to antihypertensive medication. However, suboptimal adherence remains a common problem and may lead to poor therapeutic outcomes. This literature review aimed to examine the relationship between adherence to antihypertensive medication and blood pressure control among patients with hypertension. A systematic search of the literature was conducted using the PubMed and Google Scholar databases with relevant keywords combined through Boolean operators. The selected articles were screened based on predefined inclusion and exclusion criteria, including original research articles published within the last ten years, accessible in full text, and addressing the association between medication adherence and blood pressure in hypertensive patients. The findings of the reviewed studies indicate that most articles reported a significant relationship between medication adherence and blood pressure levels. Patients with higher adherence to antihypertensive therapy tended to achieve better blood pressure control compared to those with lower adherence. Although variations in the strength of the reported associations were observed across studies, the overall direction of the relationship was consistent. These results suggest that adherence to antihypertensive medication plays an essential role in achieving optimal blood pressure control. Therefore, this review highlights the importance of continuous efforts to improve patient adherence as part of effective hypertension management strategies aimed at reducing the risk of long-term complications.

Page 37 of 37 | Total Record : 367

 33   34   35   36   37 

Filter by Year

2023 2026


Reset
Filter By Issues
All Issue Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 6 (2025): November: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 5 (2025): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 3 (2025): May: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 2 (2025): March: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2024): Januari : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 6 (2023): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan More Issue