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Sanus Medical Journal
Published by Universitas Muhammadiyah Prof. Dr. Hamka
ISSN : -     EISSN : 2745868     DOI : https://doi.org/10.22236/sanus
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Sanus Medical Journal is a peer-reviewed medical and health journal published periodically every six months. Sanus Medical Journal publishes descriptive, analytical, and experimental studies, reviews, systematic reviews, case reports, letters, and editorials in the fields of Medicine, Health, Medical and Health Education, and Islamic Medicine. The scope of Sanus Medical Journal goes beyond the boundaries of discussions in the fields of clinical medicine and health in general, by providing new insights into etiologies, determinants, distribution, management and prevention of diseases in individuals and communities. Sanus Medical Journal attempts to meet the demands of rapid developments in information and medical and health research by committing to reduce the range of online publications to around six weeks after the submission of a manuscript. Articles will be published online in advance, and the printed version included in the next scheduled edition. Sanus Medical Journal will continue to strive to improve its scientific reputation by publishing quality articles reviewed by experts who are highly competent in their respective fields. Sanus Medical Journal greatly appreciates the contributions of authors from related disciplines. Manuscripts can be sent via email to: smjournal@uhamka.ac.id or via the website https://journal.uhamka.ac.id/index.php/smj.
Arjuna Subject : Kedokteran - Farmakologi (Medis)
Articles 89 Documents
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Pengaruh Pemakaian Masker Bedah dan Masker Kain pada Wajah Sutanto, Hans; Saroso, Ade; Setyaningrum, Dyah; Ilona, Florinda
Sanus Medical Journal Vol. 4 No. 2 (2022)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v4i2.10040

Abstract

Background. Face masks are indispensable in preventing the spread of COVID-19 transmission. Face mask use can have beneficial and detrimental effects on a person. In this study, participants' faces were observed before and after wearing surgical and cloth masks for 4 hours per day for five consecutive days. Methods. The research design is experimental. Results. Thirty-two Trisakti University Faculty of Medicine employees aged 26 to 46 years and 18 men and 14 women, participated in this study. Sociodemographic data and facial examination were assessed at the start and end of the study. The research data obtained the results of p = 0.392. Conclusion. There is no significant difference between surgical and cloth masks in terms of acne, skin irritation, and redness.
Emfisema Subkutis sebagai Komplikasi pada Pasien Covid-19 dengan Penggunaan Ventilasi Mekanik Panduwaty, Lira; Trilaksmi, Antin; Cipta, Ferdy
Sanus Medical Journal Vol. 4 No. 2 (2022)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v4i2.10388

Abstract

Background. The incidence of subcutaneous emphysema in patients with severe pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infection has been in the spotlight recently. Subcutaneous emphysema is a rare complication. With the increasing prevalence of subcutaneous emphysema in patients with confirmed coronavirus disease (COVID-19), it is necessary to know what factors can cause this and how to treat it. Case Description. Two patients, a man and a woman aged 50 and 70 years, diagnosed with COVID-19, came to the Emergency Room (IGD) of Bunda Menteng General Hospital, Jakarta, with symptoms of acute respiratory distress syndrome (ARDS). Both patients experienced severe shortness of breath with a respiratory rate above 30 times per minute. Then the two patients were treated in the intensive care Unit (ICU) isolation room and required mechanical ventilation assistance. After 3-4 days of mechanical ventilation treatment, subcutaneous emphysema develops, characterized by subcutaneous crepitus. After chest x-rays were carried out in both patients, the results were subcutaneous emphysema and pneumomediastinum. Several invasive procedures have been performed, such as subcutaneous insertion of an intravenous cannula, mediastinoscopy, and chest tube insertion. Conclusion. Complications of subcutaneous emphysema in COVID-19 patients are rare and require further research to determine the cause, where the infection is still the focus. With this case report, it is hoped that clinicians will pay more attention to the initial clinical findings of subcutaneous emphysema to reduce even more severe complications such as pneumothorax.
Hubungan antara Karakteristik Calon Pengantin Wanita dengan Pengetahuan tentang Kesehatan Reproduksi di Puskesmas Tunjung Kecamatan Randuagung Kabupaten Lumajang Jawa Timur Alya Kirana, Deifa Syaldillah; Sukarya , Wawang Setiawan; Pudyastuti , Erlina
Sanus Medical Journal Vol. 6 No. 1 (2024)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v6i1.10710

Abstract

The maternal mortality rate in Indonesia is still high at 4,400/100,000 births, likewise in Lumajang Regency at 97/100,000 live births. Various factors that influence the high maternal mortality rate include knowledge about reproductive health. In Lumajang Regency there is a regent's regulation about prospective bride and groom must report to the Puskesmas to obtain reproductive health information. Until now, in the coverage area of Tunjung Health Center, Lumajang Regency are not known about the connection between characteristics of the prospective bride and groom with knowledge about reproductive health, this research was conducted to find out. An observational analytic survey with cross sectional approach are used in this research. Fifty research samples were determined by the Lemeshow formula and total sampling technique. Data were collected using questionnaire that was created and validated. The results showed that most of the prospective brides were aged 20 to 35 years (63.64%), while the risk group in terms of age <20 years was 36.36%. Most of education of the bride-to-be is in junior high school (52.73%) and 12.73% are elementary school. The highest income for prospective brides is under 2 million (69.09%) with 14.55% of them earning below 1 million. Sourcemost reproductive health information from teachers (47.27%) and parents (21.82%), the respondent group of prospective brides with less knowledge are only 5.45%. The results of statistical analysis with Pearson chi-square test showed there is a significant relationship between age and the level of knowledge of reproductive health. Keywords: age, education, income, reproductive health
Gambaran Tingkat Kecemasan Pada Penderita Diabetes Melitus Tipe-II di RSUD Pesanggrahan,Jakarta Selatan Winarso, Rizka Suhartini; Darwin, Prasilia; Indriyati, Leli Hesti
Sanus Medical Journal Vol. 6 No. 1 (2024)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v6i1.10714

Abstract

Diabetes Mellitus merupakan suatu penyakit kronis yang disebabkan karena pankreas tidak cukup menghasilkan hormon insulin atau saat tubuh tidak mampu menggunakan insulin yang dihasilkan oleh pankreas. Kecemasan merupakan suatu kondisi aprehensi atau kekhawatiran yang merujuk pada sesuatu hal tidak baik yang akan terjadi. Banyak faktor pemicu kecemasan contohnya kondisi kesehatan, masa depan, pekerjaan, dan hubungan sosial. Penelitian ini dilakukan untuk melihat gambaran tingkat kecemasan pada penderita diabetes mellitus tipe-II. Penelitian ini menggunakan desain penelitian analitik dengan pendekatan cross sectional. Instrumen penelitian yang digunakan adalah dengan kuisioner Zung Self-Rating Anxiety Scale (SAS/ZRAS) yang terdiri dari 20 pertanyaan. Hasil penelitian menyatakan bahwa gambaran tingkat kecemasan berpengaruh pada penderita diabetes mellitus tipe-II dengan nilai likelihood ratio sebesar 0.005 < 0.05. Hasil penelitian menunjukkan bahwa kecemasan tingkat ringan lebih banyak dirasakan pada penderita diabetes melitus tipe-II.
Hubungan Tingginya Nilai ANC (Absolute Neutrophil Count) dengan Kejadian Apendisitis Akut dan Perforasi di RS Islam Jakarta Pondok Kopi Pada Tahun 2018-2020 Amalia, Amirah; Hasan, Fahad; Wahyuni, Ira; El Anshori, Mohamad Riza; Nurusshofa, Zahra
Sanus Medical Journal Vol. 5 No. 1 (2023)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i1.10715

Abstract

Apendisitis adalah kejadian peradangan pada apendiks vermiformis. Penelitian ini melihat hubungan antara tingginya nilai Absolute Neutrophil Count (ANC) dengan kejadian apendisitis akut dan perforasi. Penelitian ini dilakukan menggunakan desain analitik observasional dengan pendekatan cross sectional. Hasil penelitian menyatakan bahwa terdapat hubungan yang signifikan antara tingginya nilai ANC dengan kejadian apendisitis akut dan perforasi dengan nilai p value sebesar 0.000. Juga ditemukan cut off nilai ANC antara apendisitis akut dan perforasi sebesar 9053 sel/µL dengan sensitivitas sebesar 100% dan spesifisitas sebesar 72,6%. Hasil penelitian menyarankan bahwa penghitungan nilai ANC dapat digunakan sebagai pemeriksaan alternatif untuk penegakan diagnosis apendisitis, namun tidak dapat dijadikan sebagai satu-satunya tolak ukur untuk membedakan antara diagnosis apendisitis akut dan perforasi.
Uji Antibakterial dari Ekstrak Etanol Biji Mangga (Mangifera indica L) Terhadap Bakteri Salmonella typphimurium Adinda Octaviani; Zaim, Muhammad; Avissa, Rizkyana
Sanus Medical Journal Vol. 5 No. 1 (2023)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i1.10719

Abstract

Abstrak Bakteri Salmonella sp. adalah bakteri gram negatif yang dapat menyebabkan penyakit demam tifoid. Terapi demam tifoid adalah antibiotik seperti kotrimoksazol, kloramfenikol, dan ampisilin. Namun, menurut Badan Litbang Kesehatan, didapatkan Salmonella sp. menunjukkan resistensi sebesar 71% terhadap kotrimoksazol, 57% terhadap kloramfenikol, dan 42% terhadap ampisilin. Oleh karena itu, dibutuhkan bahan alami alternatif untuk memperoleh senyawa antibakteri baru. Salah satu bahan alam yang dapat digunakan adalah biji mangga. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri terhadap bakteri Salmonella sp dari ekstrak biji mangga (Mangifera indica L). Ekstraksi biji mangga menggunakan metode maserasi dengan pelarut etanol 96% yang dilanjutkan dengan pengujian kandungan fitokimia. Hasil uji fitokimia menunjukkan bahwa ekstrak biji mangga mengandung senyawa alkaloid, saponin, tanin, fenolik, flavonoid, tritepernoid, steroid, dan glikosida. Pada penelitian ini dilakukan uji coba perendaman cakram dengan variasi waktu perendaman cakram di ekstrak selama 5 menit, 15 menit, 6 jam, 12 jam, dan 24 jam. Kemudian dilanjutkan dengan peletakan cakram di medium yang mengandung bakteri Salmonella typhimurium sesuai dengan metode difusi cakram. Dari hasil yang didapat, zona hambat muncul secara optimal pada perendaman cakram selama 24 jam. Oleh karena itu, dilakukan perendaman cakram selama 24 jam pada ujicoba antibakteri dengan konsentrasi ekstrak 2.000 ppm, 10.000 ppm, 50.000 ppm, dan 100.000 ppm. Hasil dari penelitian ini adalah ekstrak biji mangga memiliki aktivitas antibakteri terhadap bakteri Salmonella typhimurium yang dapat terlihat mulai dari konsentrasi ekstrak 50.000 ppm dan 100.000 ppm.
Hubungan Indikasi Tingkat Adiksi Ponsel Pintar Dengan Konsentrasi Belajar Pada Pelajar Sma Jakarta khoirunisa, irbah; Susanto, Joko; Yasiro, Takashi
Sanus Medical Journal Vol. 6 No. 1 (2024)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v6i1.10772

Abstract

Penggunaan ponsel pintar semakin bertambah dikarenakan adanya perkembangan teknologi yang semakin pesat serta sangat mudah diakses dari berbagai golongan umur. Di Indonesia penggunaan ponsel pintar yang terhubung dengan internet sebanyak 95,4%. Penggunaan terus menerus yang menyebabkan gangguan pada kegiatan sehari-hari dapat menyebabkan Adiksi Ponsel Pintar. Pada Pelajar Penggunaan ponsel pintar dapat menganggu konsentrasi belajar yang menyebabkan terganggunya proses belajar mengajar. Penelitian ini menggunakan metode penelitian observasional dengan pendekatan cross sectional pada pelajar SMAN 47 Jakarta. Kuesioner yang digunakan adalah kuesioner Smartphone Addiction Scale Short Version (SAS-SV) dan Learning Consentration yang sudah di translasi ke bahasa Indonesia dan memiliki nilai alpha cornbach 0,911 untuk SAS-SV dan 0.9050 learning consentration Hasil gambaran Tingkat Adiksi Ponsel Pintar dan Konsentrasi Belajar yang selanjutnya akan dilihat hubungannya dengan uji statistik Chi-Square. Berdasarkan hasil penelitian tidak didapatkan hubungan bermakna antara indikasi ponsel pintar dengan konsentrasi belajar siswa (P=0,506).
Monosodium Glutamat (MSG) dan Gambaran Histologis Otak: Implikasi terhadap Pembentukan Otak Mencit Tan, Suriyani; Machrumnizar, Machrumnizar; Yunus Slamet, Muhamad Andanu
Sanus Medical Journal Vol. 5 No. 1 (2023)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i1.11335

Abstract

Abstract BACKGROUND The sodium salt of glutamic acid, monosodium glutamate (MSG), is a white crystalline compound (glutamic acid). MSG was first produced in large quantities in early 1963 by Korea and Japan which then spread to other countries, including Indonesia. The medical profession is concerned about the detrimental consequences of MSG because of its widespread and uncontrolled consumption. The histological differences between the cerebellum of MSG-treated and MSG-free rats are of interest to researchers. METHOD The Post Test-Only Control Group design was used in this study and used data collected for 14 days. This study used 30 male mice of the Swiss Webster type (Mus Musculus) which were reared as pure strains through inbreeding. Mice taken were 8 weeks old weighing 20 – 40 grams and divided into three groups, each consisting of nine mice with one tail in reserve for each group. One group as a control and two groups will receive MSG orally, each at a dose of 3 mg and 8 mg. Termination of mice was carried out by means of dislocation of the cervical vertebrae and continued with preparation of mice brain tissue preparations. Data analysis, which was obtained from observing the histological appearance of the mouse brain, used the Paired-Sample T test in the SPSS (Statistical Product and Service Solutions) version 20.0 for Windows with a significance level of 0.05. RESULTS In this study, there was no difference in the histological appearance of the brain cerebellum of mice in the control group and the administration of 3 mg and 8 mg of MSG. However, there was a greater increase in body weight in mice given 3 mg of MSG compared to the group given 8 mg of MSG and controls, the average weight gain was 2.87 mg. CONCLUSION After observing through a microscope on the brain preparations of control mice, MSG 3 mg and MSG 8 mg, no difference in histological appearance was found. But giving MSG to mice affects weight gain.   Abstrak LATAR BELAKANG Garam natrium dari asam glutamat, monosodium glutamat (MSG), adalah senyawa kristal putih (asam glutamat). MSG pertama kali diproduksi dalam jumlah besar pada awal tahun 1963 oleh Korea dan Jepang yang kemudian menyebar ke negara lain, termasuk Indonesia. Profesi medis prihatin dengan konsekuensi merugikan dari MSG karena konsumsinya yang meluas dan tidak terkendali. Perbedaan histologis antara otak kecil tikus yang diberi MSG dan bebas MSG adalah hal yang menarik untuk diketahui. METODE Desain Post Test-Only Control Group digunakan dalam penelitian ini dan menggunakan data yang terkumpul selama 14 hari. Penelitian ini menggunakan 30 ekor mencit jantan jenis Swiss Webster (Mus Musculus) yang dipelihara sebagai galur murni melalui perkawinan sedarah. Mencit yang diambil berumur 8 minggu dengan berat 20 – 40gram dan dibagi menjadi tiga kelompok, masing-masing terdiri atas sembilan ekor mencit dengan cadangan satu ekor untuk setiap kelompok. Satu kelompok sebagai kontrol dan dua kelompok akan menerima MSG secara oral, masing-masing dengan dosis 3 mg dan 8 mg. Terminasi mencit dilakukan dengan cara dislokasi vertebra servikal dan dilanjutkan pembuatan preparat jaringan otak mencit. Analisis data, yang diperoleh dari pengamatan gambaran histologis otak mencit, menggunakan Paired-Sample T test pada program SPSS (Statistical Product and Service Solutions) versi 20.0 for Windows dengan tingkat kemaknaan 0,05. HASIL Pada penelitan ini tidak ditemukan adanya perbedaan pada gambaran histologis cerebellum otak mencit pada kelompok kontrol dan pemberian MSG 3 mg dan 8 mg. Namun, terdapat peningkatan berat badan lebih banyak pada mencit yang diberikan MSG 3 mg dibandingkan dengan kelompok yang diberikan MSG 8 mg dan kontrol, rata-rata kenaikan berat badan sebesar 2,87 mg. KESIMPULAN Setelah dilakukan pengamatan melalui mikroskop pada preparat otak mencit kontrol, MSG 3 mg dan MSG 8 mg, belum ditemukan perbedaan gambaran histologis. Tetapi pemberian MSG pada mencit mempengaruhi pertambahan berat badan.
Hematological parameters of COVID-19 patients at Jakarta Pondok Kopi Islamic Hospital Sanjaya, Arief Indra; Martalena, Dewi; Maki, Naoki
Sanus Medical Journal Vol. 6 No. 1 (2024)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v6i1.12668

Abstract

Background: The 2019 Corona Virus Disease (Covid-19) has become a pandemic. As of 15 January 2021, 223 countries have been infected, with a total number of 92,262,621 confirmed cases, and 1,995,037 deaths. In Indonesia, as of the same date, there were 896,642 confirmed cases and 25,767 deaths.1 Diagnosis of COVID-19 is based on real-time reverse transcriptase-polymerase chain reaction (RT-PCR) results on oropharyngeal/nasopharyngeal swab samples.2 A basic hematological examination is also conducted on patients with suspected COVID-19. The results of baseline hematological examinations are thought to be a predictor of the patient being infected with COVID-19 before the RT-PCR results are released. The purpose of this study is to identify the hematological parameters of COVID-19 patients at Pondok Kopi Islamic Hospital in Jakarta (RSIJ PK) in order to provide an overview of the hematological parameters that can be used to predict the possibility of a patient being infected with COVID-19. Methods: The study adopted a cross-sectional approach, using the database on COVID-19 patients at Pondok Kopi Islamic Hospital. Data variables were categorized and described by frequency and percentage. Statistical analysis was conducted using the likelihood ratio test and SPSS (statistical package for the social sciences) version 26. Results: The number of research respondents was 250, with 142 males (56.8%). The majority of participants were between the ages of 40 and 59, at 127 (50.8%). Most patients exhibited a moderate level of clinical severity, at 215 (86%). The three most common comorbidities were hypertension in 82 patients (32.8%), diabetes in 68 patients (27.2%), and chronic kidney disease in 27 patients (10.8%). The dominant hematological parameters were normal blood leukocytes in 157 patients (62.8%), increased Neutrophil/Lymphocyte Ratio (NLR) (>3.13) in 148 patients (59.2%), low Absolute Lymphocyte Count (ALC) (<1500/µL) in 133 patients (53.2%), increased C-Reactive Proteins (CRP) (>10 mg/L) in 171 patients (68.4%), and increased d-dimer (>0.5 µg/mL) in 148 patients (59.2%). There was a significant correlation between age (p 0.028), comorbid hypertension (p 0.002), comorbid diabetes (p 0.011), leukocyte levels (p 0.045), and ALC levels (p 0.025), and the severity of the COVID-19 disease. Conclusions: The majority of COVID-19 patients had normal blood leukocyte levels, increased NLR, low ALC, and increased CRP and d-dimer.
Hubungan Aktivitas Fisik Sedenter dengan Siklus Menstruasi Mahasiswi Fakultas Kedokteran UHAMKA Hanifah, Anisa Nabila Hanifah; Sukarya, Wawang Setiawan
Sanus Medical Journal Vol. 5 No. 2 (2023)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i2.14487

Abstract

High intensity physical activity affects Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) while low physical activity that leads to less body movement affects oxidative energy reserves. This study aims to determine the relationship between sedentary physical activity and the menstrual cycle of students of the Faculty of Medicine, Universitas Muhammadiyah Prof. Dr. HAMKA (UHAMKA). The research design was an observational analytic survey with a cross sectional approach. The sample size was determined by the Slovin formula, which was 92 subjects. The results showed that most of the female students (95.65%) with sedentary physical activity, and female students with abnormal menstrual cycle disorders (polymenorrhea) were 31.52% oligomenorrhea 11.96%, hypomenorrhea 64.13%, while hypermenorrhea was only 3.27%. There is no significant relationship between the level of sedentary physical activity with menstrual cycle disorders.

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