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INDONESIA
Jurnal Farmasi Galenika
Published by Universitas Bhakti Kencana
ISSN : 24069299     EISSN : 25794469     DOI : https://doi.org/10.70410/jfg
Core Subject : Health,
Medicine & Pharmacology Public Health
The aim of JFG is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences and technology. The scope of the journal is Pharmaceutical sciences, its research and its application. The journal aims to cover the latest outstanding developments in the field of Pharmaceutical science and Technology but not limited to the following branches: Pharmaceutics Pharmaceutical technogy International Regulatory Validation Techniques Industrial Pharmacy Nanotechnology Novel Drug Delivery Systems Quality Control Quality Assurance BioTechnology Bioinformatics Proteomics Biochemistry Pharmacognosy Herbal technology Pharmacology Toxicology Pharmacy Practice Pharmacoinformatics Phytochemistry Pharmaceutical Analysis Chiral Chemistry Synthetic Chemistry Drug Development Clinical Pharmacy Pharmacogenomics Pharmacetical Engineering
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 195 Documents
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Antimicrobial Candidate From Ethanol Extract And Ethyl Acetate Fraction Of Betadin (Jatropha multifida L.) Leaves Which Actively Inhibits Clinical Isolates Of Human Skin Pathogenic Bacteria And Fungi Faroliu, Goldha; Adriani, Nova; Wulandari, Sarah
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.405

Abstract

Betadin leaf (Jatropha multifida L.) is an ornamental plant in Indonesia and is rarely used, but its leaf sap has been reported to accelerate wound healing due to skin infections. This has the potential to be used for the development of new antimicrobial agents. The extraction method was carried out by maceration using 96% ethanol and fractionation with ethyl acetate. Extracts and fractions analyzed for the presence of various phytochemical constituents. Antibacterial assay used disc diffusion (Kirby-Bauer's) method towards Propionibacterium acnes, Staphylococcus epidermidis, Corynebacterium diphtheriae, Microsporum canis and Epidermophyton floccosum. Ethanol extract of Betadin leaves contained Alkaloids, Flavonoids, Phenolics, Steroids, Terpenes, Saponins, while the ethyl acetate fraction contained Alkaloids, Phenolics, Terpenes. J. multifida leaf ethanol extract has strong activity towards Microsporum canis and Epidermophyton floccosum, and has weak activity towards Propionibacterium acnes, Staphylococcus epidermidis, and Corynebacterium diphtheriae. While J. multifida leaf ethyl acetate fraction has strong activity towards Propionibacterium acnes, Microsporum canis and Epidermophyton floccosum, and has weak activity towards Staphylococcus epidermidis, and Corynebacterium diphtheriae. Based on the results of this study can be concluded that both the ethanol extract and the ethyl acetate fraction of Betadin leaves (Jatropha multifida L.) had the ability to inhibit the growth of bacteria and fungi, then can be antimicrobial candidate of herbal medicine
Pengaruh Leaflet Terhadap Pengetahuan Pasien Tentang Dagusibu Obat Antibiotik di Puskesmas Sungai Ulin Fitriah, Rahmayanti; Permatasari, Rr. Ghinaa; Ramadhani, Syahrizal; Sajidah, Ainun
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.411

Abstract

The high use of antibiotics can trigger resistance. Currently, people often make mistakes in obtaining, using, storing and disposing of drugs properly.This is one of the consequences of the lack of accurate information and the very low level of public education. Providing education on the use of antibiotics is important so that patients get maximum drug effectiveness and prevent resistance. This study aims to determine the effect of leaflets on patient knowledge about DAGUSIBU (Get, Use, Store, Discard) antibiotics at Sungai Ulin Public Health Center, Banjarbaru City. The type of research used was a pre-experiment with a one group pretest–post test research design. Sampling used a purposive sampling technique on 87 respondents. The pretest was given before education and the posttest was given 2 weeks after education. From the research results, the average value of the patient's pretest knowledge was 65.99% and the posttest was 87.83%. The statistical test method used was the Wilcoxon Signed Rank Test with an Asymp. Sig 2 tailed result of 0.000. This shows a significance value of <0.05, which means that the alternative hypothesis is accepted, where there is a significant difference in knowledge between before and after the intervention was given through leaflet media.
Pengaruh Ekstrak Daun Landep (Barleria prionitis L.) Terhadap Glukosa Darah Postprandial dan Histopatologi Pankreas Tikus Yang Diinduksi Aloksan Sabrina, Salsa; Amin, Muhammad Saiful; Yety Lindawati , Novena
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.415

Abstract

Indonesia ranks second in diabetes mellitus with 20.4 million sufferers in 2024 and will increase to 28.5 million in 2025. This condition shows the urgency of finding new alternative antidiabetic candidates that can help reduce the number of sufferers. Landep leaves contain flavonoids, saponins, tannins, triterpenoids, and phenolics, which have potential as antidiabetic agents. This study aims to determine the effect of landep leaf extract administration on postprandial blood glucose levels and histopathological improvements in the pancreas in alloxan-induced rats. This experimental study used 25 alloxan-induced rats divided into 5 groups: negative control (CMC-Na 1%), positive control (Metformin 9 mg/200g rat body weight), and landep leaf extract at doses of 100, 200, and 400 mg/kg body weight. Treatment was administered for 14 days. Data analysis was performed using SPSS with ANOVA. The results showed that landep leaf extract at a dose of 400 mg/kg BW had a significant effect on reducing postprandial blood glucose spikes (p=0.634) compared to the positive control metformin, as well as a significant effect on improving the area of the islets of Langerhans (p=0.978) compared to the positive control. Thus, landep leaf extract has an effect on reducing postprandial blood glucose spikes and provides an improvement in the histopathology of the pancreas of alloxan-induced rats.
Formulasi Dan Evaluasi Fisik Lipstik Dari Ekstrak Kulit Umbi Bit (Beta vulgaris L.) Eryani, Mikhania Christiningtyas; Aditama, Agnis Pondineka Ria; Husni, Patihul; Permatasari, Lina Putri
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.417

Abstract

Lipstick is a cosmetic used to add color to the lips. Natural dyes that can be used as a lipstick component are beet (Beta vulgaris L.) skin extract. The skin of beet contains betacyanin which can give color to the lips. This study aims to determine the effect of varying concentrations of beet skin extract on the physical properties of lipstick. There are 3 lipstick formulas used with a 1% (F1), 2% (F2), and 3% (F3) concentration of beet skin extract. The research results show that F1 is pink, F2 is red, and F3 is dark red. The entire formula has even spreadability. The pH values of F1, F2, and F3 are 4.9±0.173, 5±0.3, and 5.3±0, respectively. The melting points of F1, F2, and F3 are 50.66±1.15°C, 52.66±1.15°C, and 53.66±0.58°C, respectively. The conclusion of this study is that variations in the concentration of beet extract affect the color, pH, and melting point of lipstick but do not affect the spreadability of lipstick.
Pengembangan Sediaan Losio Ekstrak Buah Naga Putih Husni, Patihul; Budianto, Muhamad Oke; Baitariza, Ardian; Eryani, Mikhania Christiningtyas; Febryanto, Hery Diar; Januarti, Melinda
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.419

Abstract

White dragon fruit (Hylocereus undatus) is a tropical fruit from a type of cactus plant that contains various powerful antioxidants. The purpose of this study was to obtain the best lotion formula containing extract of white dragon fruit based on physical evaluation. Three lotion formulas (F1, F2, F3) containing 7,5% white dragon fruit extract were prepared in this study. Physical assessment of the lotion preparation included organoleptic tests, homogeneity, pH determination, and viscosity evaluation. The results showed that the preparation was in the form of a liquid and homogeneous lotion with a white color and a rose odor. The pH of the preparation was around 5.2-6.5 with a viscosity between 1200-1800 cps. F3 is the best lotion formula based on physical evaluation during four weeks of storage with a composition of 7.5% white dragon fruit extract, 1% glycerin, 0.05% triethanolamine, 3% liquid paraffin, 0,3% methyl paraben, 2% dimethicone, 2% stearyl alcohol, 1.5% glycerol monostearate, 3% virgin coconut oil, 0.1% disodium edetate, 3% cetyl alcohol, 0.2% titanium dioxide, parfum qs, and aquadest ad 100%.

Page 20 of 20 | Total Record : 195

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