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Waras Nurcholis
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INDONESIA
Indonesian Journal of Jamu
Published by Institut Pertanian Bogor
ISSN : 24077178     EISSN : 24077763     DOI : https://www.doi.org/10.29244/jji
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology
Jurnal Jamu Indonesia (JJI) is dedicated to the exchange of information and widespread scientific understanding regarding the development of the world of herbal medicine through the publication of scientific papers. The themes of scientific papers within the scope of JJI include the theme of herbal medicine research from upstream to downstream which is not limited to ethnobotanical research and local knowledge, exploration, conservation, domestication of biological resources related to herbal medicine, variety breeding, development of Good Agricultural and Collection Practices (GACP) for herbal medicine raw materials, development of standards for raw materials and herbal medicine products, development of herbal medicine products, identification of active compounds and their synthesis, working mechanisms for the bioactivity of herbal medicine formulas, social and economic aspects related to the development of herbal medicine.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 163 Documents
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Jamu Kunir Asem: Ethnomedicine Overview by Javanese Herbal Medicine Formers in Yogyakarta Kurniawan, Febri Yuda; Jalil, Muhamad; Purwantoro, Aziz; Daryono, Budi Setiadi; Purnomo
Jurnal Jamu Indonesia Vol. 6 No. 1 (2021): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v6i1.211

Abstract

Kunir asem is one of the traditional drinks that still survive in Javanese society. The young generation needs to be introduced to the heritage of traditional herbal medicine, so that its existence is maintained. Some people judge that herbal medicine is an ancient traditional drink and does not keep up with the times. The objectives of this study are: (1) Explain the study of etnobotany which make up turmeric acid; (2) Explain how the principle of the benefits of kunir asem is based on the understanding of the seller of herbs in the Province of Yogyakarta. This study uses a qualitative method. The research data was taken with documentation, interviews, and documentation. The research data were analyzed by qualitative descriptive. The conclusion of this study is that biopharmaca plants in kunir asem are turmeric and tamarind, and some are added spices in the form of brown sugar, lemongrass, cardamom, cloves, kedawung, lime, and cinnamon. Herb sellers reveal that kunir asem can promote haids, facilitate digestion, reduce stomach acid, as an antibiotic, fresh body, and eliminate acne.
Antioxidant and Sunscreen Activity from Nanoparticles Extract of Temulawak Rhizome (Curcuma Xanthorrhiza Roxb.) And Formulation in The Form of A Cream Anarisa Budiati; Deni Rahmat; Zahirah Alwiyah
Jurnal Jamu Indonesia Vol. 6 No. 2 (2021): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v6i2.212

Abstract

Temulawak (Curcuma xanthorrhiza Roxb.) is a medicinal plant for the raw material of traditional medicine in Indonesia. Temulawak can be a source of antioxidants and natural sunscreen because of its curcumin content. This study was conducted to determine antioxidant and sunscreen activity on Curcuma rhizome extract and nanoparticles extract and making cream preparations. Extraction using the maceration methods with 96% ethanol solvent, concentrated with a rotary evaporator and the thick extract of Curcuma rhizome was made into nanoparticles by ionic gelation methods. Spray drying methods dried the nanosuspension of Curcuma rhizome extract. The nanoparticles formed were evaluated for particle size, zeta potential and particle morphology. The dry powder nanoparticles and extract of Curcuma rhizome were tested for antioxidant activity by DPPH (2,2-diphenyl-1-picrylhydrazyl) methods and sunscreen using a UV-Vis spectrophotometer at λ = 290-340 nm. The antioxidant activity showed the IC50 value of the Curcuma rhizome extract was 78.30 μg/mL and nanoextract was 116.51 μg/mL. The sunscreen testing result showed that the SPF (Sun Protective Factor) value of Curcuma rhizome extract at a concentration of 0,012% was 14.14 and nanoextracts at a concentration of 0.04% was 7.73. Curcuma rhizome extract has relatively strong antioxidant activity, while the nanoextract was moderate. The sunscreen activity of Curcuma rhizome extract and nanoextract has maximum protection and extra protection.
Effervescent Granule Formulation Combination of Coleus amboinicus Leaves Extract and Tamarindus indica Pulp Extract Erni Rustiani; Ulfa Nur Awinda
Jurnal Jamu Indonesia Vol. 7 No. 1 (2022): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v7i1.214

Abstract

Coleus amboinicus and Tamarindus indica effectively decrease glucose in the blood with work mechanisms by reducing oxidative stress in the body. Flavonoid contains in these plants was thought to play a role as anti-diabetes. This study made an effervescent granule preparation from a mixture of Coleus amboinicus leaf extract and Tamarind (Tamarindus indica) pulp, with additional ingredients of citric acid, tartaric acid, and sodium bicarbonate. The effervescence reaction masked the extract's unpleasant taste. The three effervescent granule formulas manufacture using a dry granulation method. Each formula used a different amount of acid and base. Effervescent granule testing includes organoleptic, flow rate, angle of repose, froth height, froth time, and hedonic test. The granule quality test results show that the best effervescent granule is formula 1, which contains 7% citric acid, 14% tartaric acid, and 25% sodium bicarbonate. Formula 1 had the best high froth 0.5 cm and 2 minute 18 seconds froth time and preferred by the panelists based on aroma and taste.
RETRACTION NOTICE TO: Uji Aktivitas Ekstrak Bunga Telang (Clitoria ternatea L.) Sebagai Agen Anti-Katarak Eny Kusrini; Dewi Tristantini; Ni’matul Izza
Jurnal Jamu Indonesia Vol. 5 No. 3 (2020): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v5i3.225

Abstract

​Artikel dengan judul Uji Aktivitas Ekstrak Bunga Telang (Clitoria ternatea L.) Sebagai Agen Anti-Katarak telah dilakukan pencabutan dari Jurnal Jamu Indonesia Vol. 2 No. 1 (2017), pada tautan daring http://jamu.journal.ipb.ac.id/index.php/JJI/article/view/28.Pencabutan artikel dilakukan karena permintaan author.Pemberitahuan pencabutan dari artikel tersebut dapat ditemukan pada http://jamu.journal.ipb.ac.id/index.php/JJI/article/view/225.
Ethno-Pharmaceutical Study of Medicinal Plants for Care and Treatment of Wounds in Indonesia: Systematic Data Search and Preclinical Review Kusumo, Djati Wulan; Erlita Layina Sulistiyowati; Habibatur Rohmah; Nailus Amany Melinda
Jurnal Jamu Indonesia Vol. 8 No. 1 (2023): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v8i1.232

Abstract

Ethnopharmacy study is an approach used to explore local knowledge of a particular community in the use of medicinal plants. This article discusses treatment methods and medicinal plants used for the treatment and care of wounds in several regions in Indonesia. In addition, this study is also useful to find out drugs from natural ingredients related to their bioactivity. The method used is literature study, while the data used are articles, databases and textbooks published from 2011-2021. Literature information searches are carried out using electronic search engines for articles and research journals published on several sites, such as Google, Pubmed, NCBI, Elsevier, and others. The results of the data obtained concluded that there were 27 types of plant species that were used traditionally and 15 who have already undergone preclinical testing for wound treatment and care.
Saponin Pada Bawang Putih Lokal Indonesia dan Potensi Biologinya (Saponins in Indonesian Local Garlic and Their Biological Potential) Balqis; Betty Lukiati; Mohammad Amin; Agus Muji Santoso; Jeni; Widodo
Jurnal Jamu Indonesia Vol. 7 No. 2 (2022): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v7i2.234

Abstract

This study aims to determine the various kinds of compounds from the saponin group found in local Indonesian garlic and map the biological potential of these compounds, especially the potential in the health sector. Saponins are a group of compounds characterized by the presence of foam. Saponins have various benefits both in the health, agriculture, animal husbandry, and also in the food and cosmetic industries. Fifteen compounds from the saponin group were identified from local Indonesian garlic obtained from West Papua, using Liquid Chromatography Mass Spectrometry (LCMS) and validated based on their similarity with the NCBI PubChem database. Saponin compounds in local Papuan garlic, then, their biological potential was mapped using the PASS Server and showed that there were seventeen kinds of biological potential in the saponin compound group from Indonesian local garlic. The three most dominant potencies are as anticancer, antifungal, and hypolipemic. Based on this research, it can be concluded that Indonesian local garlic has great potential to be developed and applied in the health sector, especially as an anticancer related to the saponin content in tubers.
Comparison of Antibacterial Activities of Ethanol and Methanol Extracts of Early Flower Leaves (Clitoria Ternatea L.) against Escherichia Coli ESBL (Extended Spectrum Beta Lactamase) Susi Rahmawati; Abdul, Ahwan; Fadilah Qonitah
Jurnal Jamu Indonesia Vol. 7 No. 2 (2022): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v7i2.237

Abstract

Inappropriate use of antibiotics can lead to bacterial resistance. Extended Spectrum Beta Lactamase (ESBL) is a bacterium that is resistant to beta-lactam antibiotics such as penicillins, cephalosporins and monobactams. One example of this bacterium is Escherichia coli which can cause a number of diseases such as urinary tract infections, respiratory infections, sepsis and meningitis. The leaves of the telang flower (Clitoria ternatea L.) contain a number of compounds that have antibacterial activity which are expected to be an alternative for the treatment of infections caused by ESBL Escherichia coli. This study aims to determine the antibacterial activity of ethanol and methanol extract of telang flower leaves against Escherichia coli ESBL and to compare the activities of the two extracts. The test method is experimental, namely measuring the antibacterial activity of the extract using the disk diffusion method. The results of the phytochemical screening test conducted showed that the extract tested positive contained flavonoids, alkaloids, phenolics, saponins, tannins and terpenoids. The results of the research related to the antimicrobial activity of the concentrations of 25%, 50% and 100% methanol extract produced inhibition zone diameters of 7.4 mm, 7.8 mm and 8.1 mm, while the ethanol extracts were 7.3 mm, 7.4 mm. , 7.9 mm. The positive control used, namely gentamicin, produced an inhibition zone of 9.8 mm. These results indicate that the methanol and ethanol extract of telang flower leaves affected the growth of Escherichia coli ESBL and there was a difference in the antibacterial activity of the two extracts based on statistical analysis with the Anova test with p value <0.05.
Uji Ekstrak Alkohol Daun Mengkudu (Morinda Citrifolia L) terhadap Konsentrasi Kreatinin dan Ureum Tikus Putih Jantan (Rattus Norvegicus) Nefropati Diabetes Tandi, Joni; R, Yana Novika; Lakiu, Debora Rislianti; Magfira; Dewi, Niluh Puspita
Jurnal Jamu Indonesia Vol. 8 No. 1 (2023): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v8i1.241

Abstract

Diabetic nephropathy is one of the microvascular complications of diabetes mellitus (DM). One of the clinical signs of diabetic nephropathy is an increase in urea and creatinine levels. The use of medicinal plants containing antioxidants is one of the therapeutic strategies to prevent complications of DM. The noni plant (Morinda citrifolia L), especially the leaves, contains active substances that have the potential as antioxidants to be used as supportive therapy for DM. This study aims to identify the content of active substances in noni leaf extract and determine the potential of noni leaf extract to reduce creatinine, and urea levels in diabetic nephropathy rats. Noni leaf extract was obtained by maceration using 96% ethanol, and animal models of diabetic nephropathy were obtained by induction of streptozotocin 40 mg/kg BW. The test animals were divided into six groups, namely normal control, negative control, positive control, treatment 1, 2, and 3, each given extract doses of 250, 500, and 750 mg/kg BW. The results indicated the presence of flavonoids, alkaloids, steroids, saponins, and tannins in the noni leaf extract. Giving noni leaf extract can reduce, urea and creatinine levels significantly compared to negative controls. In conclusion, noni leaf extract can potentially prevent complications of diabetic nephropathy with an effective dose of 250 mg/kg BW.
Estrogenic Effects of Kebar Grass (Biopyhtum Petersianum) in 96% Ethanol Extract and Various Solvent Fractions Mulyati Effendi; Yulianita; Herlina, Nina; Nurhikmah, Wilda
Jurnal Jamu Indonesia Vol. 7 No. 2 (2022): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v7i2.244

Abstract

This study aimed to compare antioxidant, antibacterial and toxicity tests of various types of kesambi tree bark extract (Schleichera oleosa (Lour) Oken). The research stages included extraction of kesambi stem skin from Mancak Serang sub-district with multilevel maceration techniques using 3 solvents: Methanol, n-hexane, and ethyl acetate. The extract was then tested for antioxidant activity, antibacterial, and toxicity. The results of antioxidant testing using the DPPH method, antibacterial with agar diffusion method, and toxicity test with BSLT method, the results showed that ethyl acetate extract had better antioxidant activity (IC50 7,723 ppm.) compared to extract of methanol (IC50 7,801 ppm), and n-hexane extract (IC50 8,568 ppm). Antibacterial activity showed the ability to inhibit the growth of Streptococcus aureus compared to Escherichia coli at a concentration of 10000 ppm, and the results of the toxicity test showed that ethyl acetate extract had better activity (LC50 305,17 ppm) than n-hexane extract (LC50 374, 96 ppm) and methanol extract (LC50 431,26 ppm).
The effect of Material to Solvent Ratio to The Flavonoid Content and Free Radical Scavenging Activity of Extract of Morinda Citrifolia L Leaves Ramayani, Septiana Laksmi; Fitria Rohmawati; Yasmine Savira Rahmadani
Jurnal Jamu Indonesia Vol. 7 No. 2 (2022): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v7i2.245

Abstract

The flavonoid compound in Noni leaves (Morinda citrifolia) are efficacious as free radical scavengers. This research aimed to know the influence of the ratio of materials and a solvent (M:S=1:10; M:S=1:15; M:S=1:20) on the flavonoid content and free radical scavenging activity of extract of noni leaves. Extraction was carried out using the Microwave Assisted Extraction method and the free radical scavenging activity were determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH). The results showed that the material-solvent ratio had a significant effect on the yield, total flavonoid content, and free radical scavenging activity. The material to solvent ratio 1: 20 resulted in the highest yield, total flavonoid content, and free radical scavenging activity compared to other solvent-solvent ratios.

Page 10 of 17 | Total Record : 163

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