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INDONESIA
Jurnal Kedokteran Diponegoro
Published by Universitas Diponegoro
ISSN : -     EISSN : 25408844     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.
Arjuna Subject : -
Articles 974 Documents
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INCIDENT OF DRY EYE IN FK UNDIP STUDENTS USING SMARTPHONES Purnomo, Adella Setyo; Wildan, Arief; Rahmi, Fifin Luthfia; Saubig, Arnila Novitasari
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 1 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i1.41988

Abstract

Background: Smartphone use is increasing over time and often causes Dry Eye Syndrome (DES). Dry Eye Syndrome (DES) is a multifactorial disease of the ocular surface characterized by loss of homeostasis and causes various ocular symptoms. The Schirmer test is a measurement of the tears quantity to diagnose DES. Objective: To determine the effect of smartphone use on the results of Schirmer test measurements. Methods: This was a quasi-experimental research with a pre-test and post-test design. The research subjects consisted of 36 students selected based on inclusion and exclusion criteria using consecutive sampling. The experimental group (n=18) used a smartphone for 2 hours by watching the video (film), while the control group (n=18) did not use the smartphone. Schirmer tests were carried out before and after observation for 5 minutes using Schirmer paper strips. Statistical tests used the Shapiro-Wilk test with a meaning value of p ≥ 0,05, Chi-square test, Paired t-test, Wilcoxon test, and Mann-Whitney test with a meaning value of p < 0,05. Results: There was a significant decrease in the Schirmer test results (p = 0,020) by 1,334 ± 0,8937 mm in the experimental group and a non-significant increase (p = 0,582) in the control group by 0,362 ± 0,4086 mm. There was a significant difference in the decrease of Schirmer test results between the experimental group compared to the control group (p = 0,048). Conclusion: The use of smartphones influences the decrease in Schirmer test measurement results.
The Effect of Benson’s Relaxation Therapy on Stress Levels Among Medical Students Diponegoro University Who Were Working on a Thesis Kesuma, Erlangga Hadi; Purwoko, Yosef; Muniroh, Muflihatul; Wardani, Natalia Dewi
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 3 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i3.42108

Abstract

Background: The prevalence of stress in final-year students who were working on a thesis was still quite high. Unmanaged stress could bring a negative impact on the students themselves. Benson’s relaxation therapy was a relaxation that combined deep breathing techniques with faith factor and had been known to reduce stress levels. This relaxation was easy to do, safe, and didn’t require a lot of time and money. Research related to the effect of Benson's relaxation on student stress levels was also still limited. Objective: To analyze the effect of Benson’s relaxation on stress levels in students of the Faculty of Medicine Diponegoro University who were working on a thesis. Methods: Quasi-experimental study with pre-test and post-test design. This research involved 64 final-year medical students and divided into two groups. A consecutive sampling technique was performed. The experimental group (n=32) were instructed to do Benson’s relaxation therapy for 14 days, each day 2 session for 10 minutes, and the control group were instructed to not do any exercise and other relaxation. The stress levels was measured with the Perceived Stress Scale (PSS). Data’s significance was analyzed with paired sample T-test and independent sample T-test. Results: A significant decrease (p<0,001) in stress level before and after Benson relaxation, from 16,34 ± 6,91 to 11,31 ± 4,79. The post-test stress level of the experimental group (11,31 ± 4,79) was significantly (p=0,001) lower than the control group (16,09 ± 5,79). Meanwhile, there were no significant differences on the pre-test stress level between two groups (p=0,781). Conclusion: Benson’s relaxation reduced stress levels in students of the Faculty of Medicine Diponegoro University who were working on a thesis.
The Art of Anti-Snake Venom Administration in Snakebite Grade III Following Viper Snakebite in Developing Country: A Case Report Kinanti, Hapsari; Kusumanegara, Agung
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 5 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i5.43109

Abstract

Snakebite remains a prior Neglected Tropical Disease in the World, especially in South-East Asia. There were many diversities in the management of snake bites based on the different levels of clinician experience. Anti-snake venom remains the mainstay treatment in venomous snakebites, meanwhile, the distribution of anti-snake venom is very sparse. Snakebite is time-limited and could be a life-threatening event. This case report described a delayed anti-snake venom administration in snakebite grade III following a viper snake bite. Tight observation including clinical manifestation and laboratory tests is the foremost thing to do in managing snakebite, due to its unpredictable clinical manifestation. Anti-snake venom dosage must be decided based on the progress of clinical manifestation and laboratory results. 
The Relationship of Energy Adequacy with Nutritional Status of Soccer Athletes of Indonesian Soccer Association Shahab, Fatinah; Zahra, Syarifah; Candra, Aryu
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 1 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i1.40173

Abstract

Background: soccer is a sport that requires a high level of energy. The combination of training and adequate nutrition can make better sport performance. Nutritional status can determine the quality of athlete while competing and reducing the risk of illness and injury. Objective: This study aimed to determine the relationship between energy adequacy levels and the nutritional status of PSIS athletes. Methods: This correlational descriptive used a cross sectional design. Subjects were observed for a 2 months period. A total of 104 soccer athletes participated in thus study. The instrument of this research includes food recall and physical activity checklist for 3 x 24 hours, digital scale, Skinfold Caliper-Thickness and microtoise. Research variables include the level of energy adequacy, body mass index, and percent body fat. Results: The result showed that the energy adequacy level was 101 athletes (97.1%), normal nutritional status was 70 athletes (66.7%) and normal body fat percent was 71 (67.6%). The relationship between the level of energy adequacy and the percentage of body fat in PSIS athletes with a p-value of 0.56 (>0.05) and a correlation with an r value of 19%. The level of energy adequacy has a significant relationship with the percentage of body fat. Conclusion: it is recommended that dietary habit should be planned to improve the performance in sport fields.    
Evaluation of the Quantity and Quality of Antibiotic Use in Inpatient Pediatric Urinary Tract Infection (UTI) Patients at RSUD KRMT Wongsonegoro Semarang Gusa, Putri Heryalien; Annisaa', Eva; Dini, Intan Rahmania Eka
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 3 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i3.41447

Abstract

Background: Antibiotics are the main drug in the treatment of various infectious diseases. The high use of antibiotics can cause bacterial resistance to antibiotics so it is necessary to evaluate antibiotics both in quantity (amount of antibiotics used) and quality (accuracy of antibiotic use).Objective: This study was conducted to determine the quantity and quality of antibiotic use in pediatric urinary tract infection (UTI) patients hospitalized at KRMT Wongsonegoro Hospital Semarang.Methods: This study was a retrospective cross-sectional study. The study materials were medical records of pediatric UTI patients who were hospitalized at KRMT Wongsonegoro Hospital Semarang. Analysis was performed qualitatively using the Gyssens method and quantitatively using the ATC/DDD and DU90% methods.Results: There were 46 prescriptions from 43 pediatric UTI patients. The most commonly used single antibiotic was ceftriaxone (47.73%). Evaluation of the quantity of antibiotic use obtained the total DDD (Defined Daily Dose) value of pediatric UTI patients in the 2019-2022 period was 40.39 DDD/100 patient-days. Antibiotics that fall into the DU90% segment are ceftriaxone and cefotaxime. Evaluation of the quality of antibiotic use obtained 8 of antibiotic use is appropriate/wise.Conclusion: There is still inappropriate antibiotic use in pediatric UTI patients at KRMT Wongsonegoro Hospital in 2019-2022.
The Correlation between Duration and Frequency of Writing Activities on Subjective Complaints of Carpal Tunnel Syndrome Widyaningtyas, Hana; Setiawati, Erna; Kesoema, Tanti Ajoe
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 5 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i5.46140

Abstract

Background: In 2020, lectures were passed online due to the pandemic Covid 19, but now it is offline as before. This method has increased hand duration for writing. Using a hand for long and repetitive duration can affect pathological abnormalities on the nerves that lead to complaints such as soreness, pain, numbness, and weakness. Of these symptoms, 90% refer to a pathological disorder named Carpal Tunnel Syndrome (CTS).Objective: To determine the relationship between writing activities and subjective complaints of CTS using research subjects of students of the Department of Medical Science, Faculty of Medicine, Universitas Diponegoro Semarang Indonesia. Methods: This study is analytical with a crosssectional method. CTS complaints were measured Boston Carpal Tunnel Syndrome Questionnaire(BCTS-Q). Data analysis was performed using univariate analysis and Spearman correlation bivariate analysis. Results: 99 respondents fit the criteria that experience subjective complaints of CTS based on the BCTS-Q; 69.7% mild, 4% moderate, and 1% very severe. There was no correlation between duration (p= 0.852), frequency (p = 0.824), and rest time of writing (p = 0.285) with subjective complaints of CTS. It could be the cause of high subjectivity in interpreting the severity of CTS without a physical examination and difficulty in recalling the time they needed to write in one week. Conclusion: There is no relationship between the duration, frequency, and length of rest time of writing and subjective complaints of CTS.
Effects of Garcinia Mangostana Linn Pericarp Extract and Physical Exercise on Atheroembolic Histopathologic Features Kidney in Wistar Rats with Metabolic Syndrome Perdana, Evangga Yudha; Miranti, Ika Pawitra; Kholis, Fathur Nur; Wijayahadi, Noor; Setiawan, Andreas Arie
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 2 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i2.42578

Abstract

Background: Renal atheroembolism is an under-recognized cause of renal failure. Atheroembolism is caused by cholesterol crystals from ulcerated atherosclerotic plaques and is influenced by inflammation and endothelial dysfunction. The formation of complicated atherosclerotic lesions is a prerequisite for the development of cholesterol crystal emboli. The exact incidence of atheroembolism remains unclear due to frequent underdiagnosis. In a previous report, the rate of embolism in the kidney among patients dying after surgery for acute atherosclerosis of the aorta was 77%. Non-pharmacological therapeutic management (such as diet and physical exercise) is an important factor in preventing and reducing the risk of atherogenesis. Prior research suggests that controlling body weight, primarily through physical exercise, is a critical factor in preventing and reducing the risk of atherogenesis, in addition to medication adherence and other therapeutic management alternatives. Another study found that mice with metabolic syndrome given Garcinia mangostana pericarp can reduce inflammatory cell infiltration, thereby reducing physiological symptoms, metabolic syndrome, liver disorders, and cardiovascular symptoms. The combination of physical exercise and metabolic supplements in the treatment was even able to significantly reduce atheroma plaque area as well as the incidence of plaque rupture, and prolong survival time. Objective: To investigate the effect of Garcinia Mangostana Linn Pericarp administration along with Physical Exercise on the histopathologic features of renal atheroembolism in Wistar rats with metabolic syndrome. Methods: This study is a true experimental study with research subjects in the form of male Rattus norvegicus Wistar rats which were randomly divided into 3 groups. All groups were induced metabolic syndrome through the administration of a diet similar to the "Western" purified atherogenic diet patent Envigo® formulated as a high fat diet (20 - 23% BW; 40 - 45% kcal from fat), saturated fatty acids (SFA >60% of total fatty acids), and drinking tap water ad libitum. However, in group K (no additional treatment), P1 (garcinia pericarp extract 800 mg / kg / day with physical exercise), and P2 (nanoemulsion garcinia pericarp extract 50 mg / kg / time of administration with physical exercise). Results: In the group treated with garcinia pericarp extract 800 mg/kg bw/day with physical exercise and the group with nanoemulsion 50 mg/kg bw/day with physical exercise, there were no fatty streaks, inflammation, and impaired myocyte coherence. There was 0-5% fibrous connective tissue, one layer of foam cell layer and myocyte-lipid, no cholesterol crystal embolism was found. Conclusion: The administration of Garcinia Mangostana Linn pericarp extract and/or nanoemulsion with physical exercise can have an effect on the histopathological picture of the kidneys of Wistar rats with metabolic syndrome, although there was no difference in effect between the two treatments.
Comparison of Intravenous Indocyanine-Green and Inflation-Deflation Method in Lung Segmentectomy: A Meta-Analysis Al Asrory, Haidar Ali Robbani; Imania, Hana
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 4 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i4.44956

Abstract

Background: Inflation-deflation technique had been a conventional method for delineating the intersegmental plane during lung segmentectomy. Over the last decade, the use of icg has shown a significant increase as an alternative method. According to the European Society of Thoracic Surgeons' (ESTS) newly released expert consensus recommendations, Systemic ICG is the preferred method for performing ISP delineation. Objective: This study aimed to determine the safety of intravenous ICG in lung segmentectomy compared to inflation-deflation method. Methods: PubMed, Science direct, and Scilit were systematically reviewed. Studies comparing ICG with inflation-deflation method in lung segmentectomy were included. The main outcome included operation time while blood loss, length of hospital stay, and air leakage event became secondary. Odd Ratio (OR) and Mean Difference (MD) with 95% of Confidence Interval (CI) were applied for dicotomous and continous variable, respectively. Heterogeneity was assessed using Cochrane Q and I statistics, as reviewers also manually tested for heterogeneity with sensitivity analysis. Results: Six studies with a total of 839 patients were retrieved. All of them were retrospective comparative studies, mainly with a diagnosis of pulmonary nodules. Most studies utilized peripheral vein injections of 2.5 mg/mL ICG solution, which had a dosage range of 3–10 mL. Intravenous ICG administration was associated with a noticable operation time [MD = -19.30, 95% CI -28.29 to -10.31, p < 0.00001], length of hospital stay [MD = -0.61; 95% CI -1.16 to -0.06, p = 0.03], as well as a significant OR observed in the number air leakage [OR = 0.39; 95% CI 0.20 to 0.75, p = 0.005]. Meanwhile, there was no significant difference in the amount of bleeding between the inflation-deflation group and the ICG group [MD = -5.18, 95% CI -12.08 to 1.72, p = 0.14]. Conclusion: This meta-analysis has demonstrated statistically that the duration of surgery, length of hospital stay, and the probability of postoperative air leak are significantly lower with the application of ICG in lung segmentectomy.
Factors Associated with The Choice of Place of Delivery in Coastal Communities in The Working Area of Bonegunu Community Health Center North Buton District Hamsah, Sitti Al Aaliatin; Saimin, Juminten; Zainuddin, Asnia
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 2 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i2.41072

Abstract

Background: Delivery assistance by health workers in North Buton District in 2022 was still very low at 89.7% and delivery at non-health facilities was 10.3%. At Puskesmas Bonegunu, the coverage of delivery at health facilities was 61.4%, and delivery at non-health facilities was 38.6%. Purpose: To analyze the factors related to the choice of place of delivery in North Buton Regency. Methods: A cross-sectional study design among 127 respondents. The research sample was taken by using total sampling technique. The research data were analyzed using multiple logistic regression tests. Results: test of the relationship between access and the choice of place of delivery obtained values (p = 0.000), socio-cultural (p = 0.002), family support (p = 0.010), knowledge (p = 0.028), and income (p = 0.000). Conclusion: access, socio-culture, family support, knowledge, and income are related to the choice of place of delivery in the coastal community in the working area of the Bonegunu Health Center 
Correlation between TGF-β Levels and Degree of Wound Healing in Leprosy Ulcer Patients: An Observational Study at dr. Rehatta Regional Hospital Jepara Alfarizi, Rizki; Yuniati, Renni; Mundhofir, Farmaditya Eka Putra; Wijayahadi, Noor; Nindita, Yora
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 3 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i3.44999

Abstract

Background: Ulcers are one form of chronic wounds as one form of complication experienced by leprosy sufferers. In the process of healing wounds such as ulcers, TGF-β has a broad role. Several studies have stated that in chronic wound conditions there is a decrease in TGF-β levels so that the wound is increasingly difficult to heal. This study aims to determine the relationship between TGF-β serum levels and the degree of ulcer wound healing. Methods: This study is an observational analysis study with a cross-sectional design and involved 33 leprosy ulcer patients undergoing treatment at the dr. Rehatta Jepara Hospital in the period March-April 2024. Serum TGF-β levels were measured using the Enzyme-linked immunosorbent assay (ELISA) method while the degree of wound healing was assessed by scoring the Pressure Ulcer Scale for Healing (PUSH). Bivariate analysis using the Spearman Correlation Rank Test. Results: The correlation test between serum TGF-β levels and the degree of wound healing (p = 0.807) and duration of leprosy as covariate (p = 0.96) showed insignificant results. Conclusion: There is no relationship between serum TGF-β levels and the degree of wound healing and duration of leprosy. 

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