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Media Kedokteran Hewan
Published by Universitas Airlangga
ISSN : 02158930     EISSN : 2775975X     DOI : 10.20473/mkh.v32i1.2021.1-11
Core Subject : Health,
Medicine & Pharmacology Veterinary
Media Kedokteran Hewan (p-ISSN: 0215-8930) (e-ISSN: 2775-975X) (established 1985) publishes all aspects of veterinary science and its related subjects. Media Kedokteran Hewan publishes periodically three times a year (January, May, and September). Media Kedokteran Hewan publishes original articles, review articles, and case studies in Indonesian or English, with an emphasis on novel information of excellent scientific and/or clinical quality, relevant to domestic animal species and biotechnology of veterinary medicine from researchers, lecturers, students, and other practitioners around Indonesia and worldwide.
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Articles 130 Documents
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Effect of the Extract of Dayak Onions (Eleutherine palmifolia) on the Sperm Quality of Mice (Mus musculus) Induced with Monosodium Glutamate Rahmatullah, Aldin Akbar; Sugihartuti, Rahmi; Susilowati, Suherni; Hamid, Iwan Sahrial; Suprayogi, Tri Wahyu; Rachmawati, Kadek; Safitri, Erma; Mustofa, Imam; Mulyati, Sri
Media Kedokteran Hewan Vol. 35 No. 2 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i2.2024.113-122

Abstract

This study aims to determine the effect of the extract of Dayak onions (Eleutherine palmifolia) on the motility, viability, and concentration of spermatozoa in mice (Mus musculus) induced with monosodium glutamate (MSG). This study involved 25 male mice aged 11 weeks and weighing approximately 20 g. The mice were divided into five groups, namely C- (CMC-Na 0.5%), C+ (4 mg/g BW of MSG), T1 (4 mg/g BW of MSG and 30 mg/kg BW of Dayak onion extract), T2 (4 mg/g BW of MSG and 60 mg/kg BW of Dayak onion extract), and T3 (4 mg/g BW of MSG and 120 mg/kg BW of Dayak onion extract). All treatments were administered for 52 days. The results showed no significant differences in the motility and concentration of spermatozoa between the C- (81.50 ± 4.18; 7.21 ± 0.37) and T3 (77 ± 2.74; 7.04 ± 0.13) groups (p < 0.05). In addition, the results showed significant differences in the viability of spermatozoa between the C- (83.30 ± 3.40) and T3 (77.20 ± 4.06) groups. Therefore, it can be concluded that the administration of Dayak onion extracts orally to mice induced with MSG can maintain the motility, viability, and concentration of spermatozoa.
Effect of Fermented Feeds on Weaned Piglets Experimentally Infected with Escherichia coli Karaye, Gloria Pisha; Ola-Fadunsin, Shola David; Tanko, Polycarp Nwunuji; Kudi, Caleb Ayuba
Media Kedokteran Hewan Vol. 35 No. 2 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i2.2024.130-145

Abstract

Sixty large white breed piglets aged between 28 and 35 days were randomly assigned to five replicate groups (Bu1, Bu2, Bd1, Bd2, Bs1, Bs2, Lc1, Lc2, C1, and C2) with six pigs per group. The Bu1 and Bu2 groups were fed with wet and dry basal diets, respectively, supplemented with 0.8 mL (6 x 106 colony-forming units (CFU)) of Lactobacillus isolated from burukutu (beverage made from sorghum grains). The Pg1 and Pg2 groups were fed with wet and dry basal diets, respectively, supplemented with 0.8 mL (6 x 106 CFU/mL) of Lactobacillus isolated from pig hindguts. The Bs1 and Bs2 groups were fed with wet and dry basal diets supplemented with 0.8 mL (6 x 106 CFU/mL) of Bacillus subtilis and Bacillus pumilus, respectively. The Lc1 and Lc2 groups were fed with wet and dry basal diets supplemented with 0.8 mL (6 x 106 CFU/mL) of Lactobacillus acidophilus, respectively. Meanwhile, the C1 and C2 groups as the control groups were fed with wet and dry basal diets, respectively. The treatment and control animals were infected with Escherichia coli at 6 mL (1 x 1010 CFU/mL) orally. Aseptically collected fecal samples from the piglets in each group showed significant bacteriological and pathological differences. This study suggested that Lactobacillus species isolated from burukutu, pig hindguts, and industrial probiotics could inhibit colibacillosis.
A Case Report: Treatment of Anaplasmosis and Ectoparasitic Infestation in Mixed-Breed Golden Retriever Dog Situmorang, Fernando Jose Immanuel Clinton; Suartha, I Nyoman; Jayanti, Putu Devi
Media Kedokteran Hewan Vol. 35 No. 3 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i3.2024.281-293

Abstract

Anaplasmosis is a disease in dogs caused by intracellular gram-negative bacteria belonging to the Anaplasmataceae family. A 6-month-old mixed-breed golden retriever was examined at the Laboratory of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Udayana University, with complaints of itching, tick infestation, weakness, and decreased appetite. The clinical examination revealed pale mucous membranes in the mouth and eye conjunctiva, as well as an infestation of Rhipicephalus ticks on the skin. Routine hematological examination indicated the presence of anemia and thrombocytopenia. Blood smear examination confirmed the presence of Anaplasma sp. Treatment was provided in a causative and supportive manner. Causative therapy involved the administration of doxycycline at a dose of 10 mg/kg body weight orally for twenty-eight days, ivermectin at a dose of 0.2 mg/kg body weight injected subcutaneously every two weeks for four weeks. Supportive therapy included the daily administration of Fufang E'jiao Jiang ®(Dong E Ejiao Co, Ltd., Shandong, China) at 2 ml/day and Sangobion® (PT. Merck Tbk, Jakarta, Indonesia) at  one tablet per day for fourteen days. Treatment with doxycycline, ivermectin, Fufang E'jiao Jiang® (Dong E Ejiao Co, Ltd., Shandong, China), and Sangobion® (PT. Merck Tbk, Jakarta, Indonesia) resulted in a positive outcome for the dog, with improved activity, hair growth, good appetite, and the absence of ticks.
Protective Effect of The Extract of Dayak Onions (Eleutherine palmifolia) on Sertoli and Leydig Cell Necrosis in Mice (Mus Musculus) Induced with Monosodium Glutamate Rahmatullah, Aldin Akbar; Ratnaningtyas, Nurrohmah; Sugihartuti, Rahmi; Susilowati, Suherni; Safitri, Erma; Mulyati, Sri
Media Kedokteran Hewan Vol. 35 No. 2 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i2.2024.87-96

Abstract

This study aims to determine the effect of the extract of Dayak onions (Eleutherine palmifolia) on the number of necrotic Sertoli and Leydig cells in mice (Mus musculus) induced with monosodium glutamate (MSG). This study involved 25 male mice aged 11 weeks and weighing approximately 20 g. The mice were divided into five groups, namely C- (0.5% CMC-Na), C+ (4 mg/g BW of MSG and 0.5% CMC-Na), T1 (4 mg/g BW of MSG and 30 mg/kg BW of Dayak onion extract), T2 (4 mg/g BW of MSG and 60 mg/kg of Dayak onion extract), and T3 (4 mg/g BW of MSG and 120 mg/kg BW of Dayak onion extract). All treatments were administered for 52 days. The mice were euthanized on day 53 of the experiment. Their testicles were removed and used to prepare histological specimens with the H&E staining method. The results showed significant differences (p < 0.05) in the number of necrotic Sertoli and Leydig cells between the C+ group and the T1, T2, and T3 groups with gradually decreasing values. The results suggested that the administration of the extract of Dayak onions can prevent Sertoli and Leydig cell necrosis in mice induced with MSG at an optimal dose of 120 mg/kg BW.
Analysis of Differences in Farmer Income Estimation Between Middlemen and Animeter For Bali Cattle in Jaro Subdistrict, Tabalong Regency, South Kalimantan Aulia Rakhman, Muhammad Andika; Soeharsono; Al-Arif, Moh. Anam; Lukiswanto, Bambang Sektiari; Triakoso, Nusdianto; Ma'ruf, Anwar
Media Kedokteran Hewan Vol. 35 No. 2 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i2.2024.146-156

Abstract

This study investigates differences in farmer income and body weight estimation for male and female Bali cattle in extensive farming in Jaro Subdistrict, Tabalong Regency, South Kalimantan. A random sampling approach was used, involving farmers from nine villages. Statistical analyses revealed a significant difference (p < 0.05) in the body weights of male Bali cattle measured by an animeter compared to those estimated by middlemen. In contrast, no significant difference (p > 0.05) was observed for female Bali cattle. These differences significantly impacted farmer income for male cattle because the income estimated by the animeter exceeded that estimated by the middlemen (p < 0.05). However, no significant difference (p > 0.05) was observed between the two estimation methods for female cattle. In addition, no significant relationship was observed between the estimates made by the middlemen and those made by the animeter for both sexes of Bali cattle. This study used the Monte Carlo simulation to predict demand for male and female Bali cattle in 2024. On average, farmers were able to supply between two and three male Bali cattle and between three to seven female Bali cattle per month. To ensure a steady income, farmers are advised to supply at least one male or female Bali cattle. Moreover, farmer groups are encouraged to compensate for cattle shortages or surpluses, thereby ensuring a stable supply for middlemen and consumers.
Case Report: Ehrlichia ewingii Infection in a Shih Tzu Mix Dog Nazara, Nonitema; Jayanti, Putu Devi; Suartha, I Nyoman
Media Kedokteran Hewan Vol. 35 No. 2 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i2.2024.167-178

Abstract

Ehrlichiosis is a dog disease caused by Ehrlichia, a gram-negative intracellular bacterium, and transmitted by ticks of the genus Rhipicephalus sanguineus. This case report aims to identify the infectious agent and describe the treatment for a case of ehrlichiosis. The examination results showed signs of ehrlichiosis in a male shih tzu mix dog aged three months. The dog had been suffering from itching, weakness, decreased appetite, and tick infestations over the entire body for the past month. The physical examination showed that the dog was limping and had pale oral mucosa. Meanwhile, the routine hematological examination showed signs of neutrophilia, hypochromic microcytic anemia, and thrombocytopenia. In addition, the blood smear examination showed intracytoplasmic bodies in the neutrophils of the dog. Blood tests using the test kit showed a positive result for ehrlichiosis. The dog was diagnosed with ehrlichiosis with a good prognosis. The treatment included doxycycline at a dose of 10 mg/kg BW q24h PO for 28 days, Livron B.plex at a dose of 1 tablet per day PO for 14 days, Fufang Ejiao Jiang at a dose of 1 ml per day PO for 14 days, and Bravecto Spot-on. The condition of the dog improved after seven days of treatment. However, the routine hematological examination on day seven still showed signs of anemia and thrombocytopenia, necessitating continued supportive drugs.
Case Study: Open Pyometra in a Pomeranian Dog at INI Veterinary Service Clinic Kristanto, Dwi; Nur Aini, Dina Wahyu; Willyanto, Iwan; Prasetyo, Dodik; Rickyawan, Nofan
Media Kedokteran Hewan Vol. 35 No. 2 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i2.2024.157-166

Abstract

A five-year-old female Pomeranian dog presented with vomiting, restlessness, decreased appetite, and vaginal discharge. The physical examination revealed yellowish to brownish purulent vaginal discharge with an unpleasant smell. The X-ray image showed an enlarged uterus, while the hematology results revealed hypochromic normocytic anemia, neutrophilia, lymphopenia, and thrombocytopenia. The blood chemistry test results showed abnormalities, including elevated levels of alkaline phosphatase levels (ALP) and cholesterol as well as decreased amylase levels. Based on the anamnesis, clinical findings, physical examination, and supporting examinations, it was concluded that the dog was diagnosed with open cervix pyometra. The dog was treated with oxytocin hormone at a dose of 0.5 IU/kg BW, methylergometrine at a dose of 0.125 mg/dog, enrofloxacin at a dose of 5 mg/kg BW, carprofen at a dose of 2.5 mg/kg BW, cyproheptadine at a dose of 0.5 mg/kg BW, ranitidine at a dose of 3.5 mg/kg BW, ondansetron at a dose of 1 mg/kg BW, glyseryl guaiacolate at a dose of 20 mg/kg BW, ambroxol HCl at a dose of 2 mg/kg BW, Fufang® at adose of  1 ml, Sangobion® at a dose of 100 mg/dog, Maxbiotik® at a dose of 66 mg, and Transfer Factor Plus® at a dose of 20 mg. The treatment resulted in an improvement in the animal's condition as evidenced by the absence of nasal and vaginal discharges and vomiting, as well as a stool consistency of two out of five.
Effect of Coffea canephora Bean Extract on Lead Acetate-Induced Rats Moch. Ilham Riza Fahlefi; Maya Nurwartanti Yunita; Indaka Rachmach Choirunnisa; Farodina Azka Zhafira; Fania Aulia Rahma
Media Kedokteran Hewan Vol. 35 No. 2 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i2.2024.97-104

Abstract

Lead (Pb) is a non-essential heavy metal that is toxic and has no known uses. Most cases of poisoning in livestock are caused by lead poisoning. This study aims to determine the effect of Coffea canephora bean extract as an antioxidant on the heart histopathological features of white rats (Rattus norvegicus) induced by lead acetate. This study used 25 male Wistar rats aged between eight and ten weeks and weighing between 200 and 250 grams. The rats were divided into five treatment groups, namely negative control (C-), positive control (C+), treatment one (T1), treatment two (T2), and treatment three (T3).  The results suggested that the administration of 200 mg/kg BW, 400 mg/kg BW, or 800 mg/kg BW of Coffea canephora bean extract was not effective in improving the heart histopathological features, including cell degeneration, hemorrhage, and necrosis, of rats induced with lead acetate at a dose of 2 mg/kg BW.
Analysis of Swallow Nest Nitrite Levels and Export Volume Projections: A Statistical Approach to Quality Improvement and Global Market Development Kusumawati, Anjung; Kurniawan, Muhammad 'Ahdi
Media Kedokteran Hewan Vol. 35 No. 3 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i3.2024.243-255

Abstract

The global SARS-CoV-2 pandemic is impacting public health and living systems. Edible Bird's Nest (EBN), one of the variants of Swallow's Nest (SBW), is recognized as a medicinal food. The potential of SBW as a therapeutic agent is gaining attention due to its ability to inhibit viral hemagglutination activity. This study provides information on the prediction of SBW demand in the coming year so that it can contribute to determining Indonesia's SBW export performance. Net weight data (tons) of SBW export time series were obtained for 10 years from 2012 to 2022 in 10 countries, namely: Hong Kong, China, Singapore, USA, Vietnam, Canada, Taiwan, Thailand, Japan, and Cambodia, combined with laboratory examination on nitrite levels conducted at the Surabaya Agricultural Quarantine Center, Indonesia. This study shows the minimum limit on nitrite levels in SBW exports and the need for SBW exports in the next four years. One of the requirements for SBW exports is the minimum limit of nitrite levels. The ARIMA method has been implemented to forecast SBW export demand in 10 countries for the next four years. SBW export demand in the next four years is expected to decline. The findings make a significant contribution as a source of information for decision-makers involved in SBW export activities.
Systemic Anti-inflammatory Activity of American Cockroach (Periplaneta americana) Extract: A Molecular Docking Study Aritonang, Erfan Andrianto; Gunanti; Purwono, Rini Madyastuti; Supriyono
Media Kedokteran Hewan Vol. 35 No. 2 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i2.2024.105-112

Abstract

Surgery can trigger systemic inflammatory response syndrome. This study aims to determine the effectiveness of Periplaneta americana cockroach extract as an oral systemic anti-inflammatory agent using molecular docking. The molecular docking method consisted of five steps. The first step was preparing the TNF-α converting enzyme (TACE) receptor as a native ligand, dexamethasone as a control ligand, and three test ligands of Periplaneta americana cockroach extract. The second step was docking preparation. The third step was analyzing Gibbs free energy (∆G) and root mean square deviation (RMSD). The fourth step was docking the test and control ligands with TACE. The fifth step was analyzing ∆G, inhibition constant (Ki), visualization of two- and three-dimensional interactions, percentage of binding site similarity (%BSS), and the rule of five (Ro5) on test ligands. The ∆G results for the native, control, and test ligands 1, 2, and 3 were -12.8, -7.1, -7.7, -6.9, and -9.0 kcal/mol, respectively. The Ki values for the native, control, and test ligands 1, 2, and 3 were 4.091, 6.205, 2.253, 9.521, and 2.507 µM, respectively. The results of the Ro5 analysis suggested that the three test ligands satisfied Lipinski's rule of five. This study concluded that Periplaneta americana cockroach extract is an effective oral systemic anti-inflammatory agent.

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