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All Journal Jurnal Ilmu Manajemen Jurnal Teknik Kimia USU Biology, Medicine, & Natural Product Chemistry MPI (Media Pharmaceutica Indonesiana) ALCHEMY Jurnal Penelitian Kimia Jurnal Ilmiah Manajemen "E M O R" JAB (Jurnal Akuntansi & Bisnis) Stability: Journal of Management and Business CARADDE: Jurnal Pengabdian Kepada Masyarakat JPSCR : Journal of Pharmaceutical Science and Clinical Research FITOFARMAKA: Jurnal Ilmiah Farmasi Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Analis Farmasi Oetoesan-Hindia: Telaah Pemikiran Kebangsaan Community Empowerment Advance Sustainable Science, Engineering and Technology (ASSET) Bioscientia Medicina : Journal of Biomedicine and Translational Research JAF (Jurnal Analis Farmasi) Jurnal Ilmu Manajemen SEMINAR NASIONAL PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT SWAGATI: Journal of Community Service Jurnal Sains dan Kesehatan Advance Sustainable Science, Engineering and Technology (ASSET) Berita Biologi
Marlina, Dian
Universitas Setia Budi
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Journal : Advance Sustainable Science, Engineering and Technology (ASSET)

 1 
The Effect of Storage Conditions on the Absorption Profile of 2% Lydocaine Hydrochloridum Injection by UV-Vis Spectrophotometry Dian Marlina; Sephia Febriyanti; Arsyeni Destra Anarchy Arsyandi; Nur Anggreini Dwi Sasangka
Advance Sustainable Science Engineering and Technology Vol 5, No 1 (2023): November-April
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/asset.v5i1.14937

Abstract

Lidocaine HCl injection is a sterile product that is easily contaminated when opened. The temperature and humidity in the injection storage conditions also affect the quality of the drug when viewed from the UV-Vis spectrophotometric absorption value. The aimed of this study is to find out how the effect of storage conditions on the absorption profile of 2% lydocaine HCl injection by UV-Vis spectrophotometry. The study used 27 ampoules of 2% lidocaine HCl injection and was qualitatively analyzed using UV-Vis spectrophotometry. The study lasted for 14 days by first storing the injections in storage conditions at room temperature (25-27℃), cold temperatures (5-10℃), and exposed to Ultraviolet light (380 nm). Based on the results of laboratory tests, the most suitable storage condition used for storing lidocaine HCl injection was cold storage (5-10℃) because there was no shift in the maximum wavelength as occurred during the 14th day of UV exposure storage.
Hydrogen bonding investigation of poly(3-hydroxybutyrate) / glycol chitosan blends studied by infrared and terahertz spectroscopies Marlina, Dian; Sato, Harumi
Advance Sustainable Science, Engineering and Technology Vol 1, No 1 (2019): May-October
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/asset.v1i1.4879

Abstract

Poly(3-hydroxybutyrate) (PHB)/glycol chitosan (GC) polymer blend was developed as one of the new biopolymer materials. Effects of different PHB / GC concentrations were analysed as a function of the blend compositions by using Fourier transform infrared (FTIR) and terahertz (THz) spectroscopies to investigate the changes in the higher-order structure and bonding of hydrogen. The higher-order structure and hydrogen bonding monitored in this study include the crystalline structure and (C=O…H-C) hydrogen bonding of PHB. The FTIR and THz spectra showed that PHB's higher-order structure transforms into the less-order structure by adding GC without altering the crystalline structure and PHB's intramolecular (C = O ... H-C) hydrogen bonding with increasing GC concentration. Because of the addition of GC, the intensity ratio of THz bands figure out the crystalline dynamics of PHB, the helical structure deformation occurs first followed by the weakening of intramolecular (C = O ... H-C) hydrogen bonding within PHB-PHB molecules. Keywords: Chitosan, higher-order structure, hydrogen bonding, low-frequency vibrational spectroscopy
Co-Authors 12.520.20.206 Shinta Ratnawati, 12.520.20.206 Achmad Solechan Amanda, Nathasya Gracya Anak Agung Istri Sri Wiadnyani Anang Kuncoro Rachmad Setiawan Anggraini, Natasya Dila Putri Aris Tri Jaka Harjanta, Aris Tri Arsyeni Destra Anarchy Arsyandi Asiyah, Siti Dwi Bambang Agus Herlambang, Bambang Desi Purwaningsih Febrian Murti Dewanto Fitrianingsih, Sri Ghani Nurfiana Fadma Sari Gunawan Pamudji Widodo Haryo Kusumo Haryo Kusumo Iswandi Iswandi Jason Merari Peranginangin Kusumo, Haryo Lumbantungkup, Gebi Evelin mayang, anissa Mega Novita Mega Novita Misnovita, Ghina Salsabila Nilawati, Anita Novitarini Nur Anggreini Dwi Sasangka Nurfiana Rachmawati Pramukantoro, Ganet Eko Prasetyanto, Panji Kusuma Priyanto, Widodo Purwaningsih, Avianti Eka Dewi Aditya Puspitasari, Ismi Putri, Cinthiya Ekwinta Rahayuningsih, Dwinata Rahmadita, Ivony Reny Pratiwi Reny Pratiwi Rifki Hermana Ryan Werytama Saputra Santi Kartika Dewi, Lensa Erliana Saputra, Ryan Werytama Sato, Harumi Senowarsito, Senowarsito Sephia Febriyanti Setyaningsih, Widiastuti Siti Aisiyah Siwi, Andini Prabandaru Supriyono Supriyono Supriyono Supriyono Sutomo Sutomo Vivin Nopiyanti Widiastuti Setyaningsih Yunitha, Emmellia