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Formulation of Nanoemulsion Gel Pogostemon cablin Benth. And Anti-acne Activity Heroweti, Junvidya; Mindiono, Imam Arif; Mahmud, Nurlela; Pradasari, Frisya; Fresiva, Urva; Prihantini, Malinda
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 3 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i3.60143

Abstract

Patchouli oil (Pogostemon cablin Benth.) contains patchouli alcohol, a compound known for its antibacterial properties, including activity against Propionibacterium acnes (Cutibacterium acnes), a key bacterium implicated in the pathogenesis of acne. This study aims to evaluate the anti-acne potential of a nanoemulsion gel formulation of patchouli oil using three different gelling agents: HPMC (F1), Na CMC (F2), and Carbopol 940 (F3). Each formulation was assessed for its physicochemical characteristics, including color, odor, texture, pH, adhesion, spreadability, viscosity, particle size, polydispersity index (PDI), and zeta potential. All formulations appeared milky white, retained the characteristic aroma of patchouli oil, and exhibited a smooth gel texture. Among the three, F1 demonstrated the highest viscosity, while F3 exhibited superior adhesion. The average pH value (6.19 ± 0.23) was within the acceptable range for topical application. In vivo evaluations indicated that F3 exhibited the most significant reduction in erythema and edema, with minimal irritation potential. Additionally, F3 received the highest respondent satisfaction rating (77.6%), indicating better acceptance. Based on these findings, Carbopol 940 is identified as the most suitable gelling agent for the development of a patchouli oil nanoemulsion gel with promising anti-acne efficacy and favorable respondent acceptability.
Sunscreen effectivity and physical characterization of avocado oil in nanoemulsion using isopropyl myristate variations Shabrina, Ayu; Firdausi, Zuhriya Muna; Poerba, Agnes Theresya; Setyani, Diana Anisa; Heroweti, Junvidya
Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.28214

Abstract

Unsaturated fatty acids in avocado oil can help reduce erythema brought on by prolonged UV-B exposure. The effectivity of sunscreen absorption into the skin will be enhanced by the use of isopropyl myristate (IPM) in nanoemulsion. The purpose of this study was to determine the physical characteristics and sunscreen effectiveness of avocado oil nanoemulsion (AVN) modified with IPM. 1% (FI), 3% (FII), and 5% (FIII) IPM variation were used to make AVN with 5% oil. The AVN were tested for physical characteristics such as organoleptic, pH, viscosity, rheology, particle size and polydispersity index (PI). The products were also tested for sunscreen effectivity by in vitro and Minimum Erythemal Dose (MED) method. The data obtained were analyzed statistically. The results showed that the AVN was pale yellow and clear with transmittance percentage were 96%. The rheogram showed that the products were newtonian. The pH values range were from 6.62 to 6.66; viscosity 1.65-1.84 dPa.s; particle size < 17 nm, zeta potential was in range of -30,54±1,72 to -37,85±3,11 and PI < 0.5 for all formula. In vitro SPF values were 16.43 ± 4.50 (FI), 16.27 ± 4.20 (FII) and 17.88 ± 3.20 (FIII) (p >0.05), and categorized as ultra protection. MED value were 12.28 ± 1.34 (FI); 12.51 ± 1.68 (FII); and 13.22 ± 1.84 (FIII) (p< 0.05) and categorized as maximum protection. Isopropyl myristate increased the sunscreen product's MED value without changing its physical characteristics.
Aktivitas Penumbuh Rambut Sediaan Hair Tonik Minyak Esensial Kayu Manis (Cinnamomum burmanii) and Minyak Kelapa Heroweti, Junvidya; Wibowo, Danang Novianto; Khoeriyah, Himatul; Adelia, Ramadhania
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1369

Abstract

Cinnamaldehyde in cinnamon essential oil, lauric acid, myristic acid, and oleic acid in virgin coconut oil (VCO) were used in hair tonic preparations as hair growth agents. This study aimed to evaluate particle size and obtain optimum formulation of the hair tonic preparation and to observe growth activity with various levels of cinnamon essential oil and VCO. This research an experimental with rabbit used 4 test were divided into 6 treatment groups: 1) positive control (Regrou®); 2) normal control (without treatment); 3) negative control (hair tonic basis); 4) F1(1% cinnamon essential oil: 2.5% VCO); 5), F2 (3% cinnamon essential oil : 2.5% VCO); and 6), F3 (5% cinnamon essential oil: 2.5% VCO). The particle size analysis selected in formula 2 that cycle stable during storage, and fall into the microemulsion size range of 20-200 nm and there was no difference cycle because the significance was >0.05. The hair growth activity was determined using Average Growth Daily Gain.(AGD) formula and then.was analyzed.statistically using.One Way Anova. The results showed that had hair growth activity that was not significantly different. However, when compared with the positive control, formula 3 has hair growth activity above the positive control.
Pelatihan Daur Ulang Limbah Organik Dapur Menjadi Eco Enzyme Multiguna di Lingkungan Desa Ngareanak, Singorojo Kabupaten Kendal Prihantini, Malinda; Windriyati, Yulias Ninik; Rochman, M Fatchur; Wibowo, Danang Novianto; Fresiva, Urva; Heroweti, Junvidya; Ikhsan, Muhammad; Sholehah, I Ana; Mahardika, Muhammad Farel; Najibah, Muna Ulya; Wafa, Nurul
Jurnal Vokasi Vol 9, No 3 (2025): November
Publisher : Politeknik Negeri Lhokseumawe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30811/vokasi.v9i3.7870

Abstract

Desa Ngareanak, Singorojo Kabupaten Kendal merupakan salah satu desa yang terletak di dalam area perkebunan yang jauh dari perkotaan. Lokasinya berjarak 28 km dari pusat Kabupaten Kendal dan 35 km dari pusat Kota Semarang. Sebanyak tiga perempat bagian wilayah desa adalah tanah perkebunan milik pemerintah yang terdiri dari ± 43,37% Tanah Perkebunan PTPN IX Merbuh dan ± 30,86% Tanah Perhutani RPH Ngareanak. Warga Desa Ngareanak selama ini membuang sampah organik ke wilayah perkebunan tanpa diolah terlebih dahulu, sehingga berpotensi mencemari lingkungan dan merusak asset pemerintah.  Diperlukan adanya gerakan yang massif dan terstruktur sebagai upaya pengelolaan limbah yang berdayaguna optimal. Pembuatan eco enzyme dapat mengolah sampah organik menjadi larutan yang berdayaguna. Oleh karena itu, kegiatan ini bertujuan untuk memberikan pelatihan daur ulang limbah organik dapur menjadi eco enzyme dalam upaya menjaga kelestarian lingkungan di Desa Ngareanak, Singorojo Kabupaten Kendal. Kegiatan pengabdian dilakukan menggunakan metode participatory action melalui pendekatan partisipatif berkelanjutan untuk pemberdayaan kelompok masyarakat di Desa Ngareanak. Kegiatan dilakukan melalui tiga tahapan yaitu penyampaian materi eco enzyme oleh tim dosen sebagai pembicara, pelatihan pembuatan eco enzyme dengan melibatkan masyarakat, dan evaluasi. Sebanyak 20 peserta dibagi menjadi 4 kelompok dengan setiap kelompok didampingi oleh 2 orang fasilitator dari tim pengabdian. Setiap kelompok membuat 1 wadah eco enzyme di dalam galon bekas air mineral.  Hasil pengabdian berupa empat wadah eco enzyme dengan komposisi dan jenis sampah organik yang berbeda untuk setiap kelompok. Keempat wadah eco enzyme tersebut disimpan oleh masing-masing kelompok untuk melalui masa fermentasi selama minimum dua bulan.
Pemberdayaan Kelompok Fatayat NU di Desa Karimunjawa Melalui Sistem Hidroponik Berbasis IoT Heroweti, Junvidya; Prabowo, Rossi; Wijaya, Akhmad Pandhu; Maulana, Muhamad Amir; Sofiyulloh, Muhammad Wahyu; Pratama, Arvian Randitya; Mas’ud, Muhammad; Wirayudha, Halim; Apriliyani, Dwi Nur Anisa; Shabrina, Ayu
Jurnal Vokasi Vol 9, No 3 (2025): November
Publisher : Politeknik Negeri Lhokseumawe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30811/vokasi.v9i3.7694

Abstract

Desa Karimunjawa, yang terletak di wilayah kepulauan Jawa Tengah, menghadapi tantangan serius dalam ketahanan pangan akibat keterbatasan lahan pertanian, kondisi tanah berpasir dengan nutrisi rendah, serta ketergantungan pada pasokan sayuran dari Jepara yang harganya relatif lebih tinggi. Cuaca ekstrim juga sering mengganggu jalur transportasi, sehingga distribusi pangan tidak menentu. Program pengabdian ini bertujuan meningkatkan kemandirian pangan lokal melalui penerapan budidaya hidroponik yang dipadukan dengan teknologi Internet of Things (IoT). Kegiatan dilaksanakan dengan pendekatan partisipatif, meliputi penguatan kapasitas kelompok Fatayat NU, pelatihan sistem hidroponik, pendampingan teknis, serta implementasi perangkat IoT untuk pemantauan dan pengaturan air serta nutrisi tanaman secara otomatis. Hasil kegiatan menunjukkan bahwa sistem hidroponik berbasis IoT mampu menurunkan konsumsi air hingga 30% dan memperpendek siklus panen, sehingga menghasilkan produksi sayuran yang lebih konsisten. Selain itu, program ini memperkuat kapasitas institusional mitra komunitas, meningkatkan keterampilan anggota, serta membuka peluang ekonomi berbasis pertanian berkelanjutan. Dengan demikian, kegiatan ini memberikan kontribusi nyata dalam mendukung ketahanan pangan sekaligus kemandirian ekonomi masyarakat pesisir seperti Karimunjawa.