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All Journal Jurnal Media Gizi Indonesia (MGI) Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Window of Health : Jurnal Kesehatan Al-sihah: The Public Health Science Journal Journal of Islamic Nursing Patria Artha Journal of Nursing Science Journal of Midwifery and Nursing Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal Afiasi : Jurnal Kesehatan Masyarakat Jurnal Ilmiah Kesehatan Diagnosis Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Sinergitas Multidisiplin Ilmu Pengetahuan dan Teknologi (SMIPT) Window of Public Health Journal Journal of Midwifery Care Jurnal Pengabdian kepada Masyarakat Jurnal Pengabdian Masyarakat (ABDIRA) Wal'afiat Hospital Journal Jurnal EduHealth Idea Pengabdian Masyarakat Jurnal Abmas Negeri (JAGRI) An Idea Health Journal Proceedings of the International Conference on Nursing and Health Sciences Journal of Aafiyah Health Research (JAHR) Journal of Muslim Community Health (JMCH) Jurnal Berita Kesehatan Jurnal Pemberdayaan dan Pendidikan Kesehatan Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Jurnal Pengabdian Mandiri Journal of Training and Community Service Adpertisi Jurnal Keperawatan Innovative: Journal Of Social Science Research WAL'AFIAT HOSPITAL JOURNAL Advances in Healthcare Research Jurnal Manajemen Bisnis dan Kesehatan
Andi Asrina
Fakultas Kesehatan Masyarakat, Universitas Muslim Indonesia
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Journal : Advances in Healthcare Research

 1 
Precision Medicine Approaches in Oncology: Current Trends and Future Directions Asrina, Andi
Advances in Healthcare Research Vol. 2 No. 1 (2024): September - February
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v2i1.370

Abstract

Purpose: This study examines the transformative potential of precision medicine in oncology, highlighting advancements in targeted therapies and immunotherapies and addressing both practical and theoretical challenges in clinical implementation. Research Design and Methodology: This study employs a mixed-methods design, integrating quantitative data from a cross-sectional survey of oncologists with qualitative insights from in-depth interviews with key stakeholders. Advanced bioinformatics tools and multi-omics data, including genomics, proteomics, and transcriptomics, are analyzed to identify novel therapeutic targets and biomarkers. Findings and Discussion: The findings demonstrate that precision medicine enhances patient outcomes by tailoring treatments to the genetic and molecular profiles of tumors. Targeted therapies, such as tyrosine kinase and epidermal growth factor receptor inhibitors, exhibit enhanced efficacy and reduced toxicity. Immunotherapy, remarkably immune checkpoint inhibitors, demonstrates significant promise but shows variability in patient responses, underscoring the need for predictive biomarkers. Integrating multi-omics data provides a comprehensive understanding of cancer biology and new therapeutic targets. Challenges include high costs, the need for robust bioinformatics infrastructure, and ethical considerations. Implications: This study highlights the importance of investing in bioinformatics infrastructure, establishing standardized guidelines, and providing training for healthcare providers. Policymakers should develop strategies to reduce the costs of genetic testing and ensure equitable access to precision medicine. Future research should focus on cost-effective genomic testing methods, combination therapies to overcome resistance, and expanding studies to diverse populations to enhance the applicability and accessibility of precision medicine benefits.
Co-Authors ., Arman A. Hanifah Muslimah Abd. Gafur Abd.Hady J Adam Badwi, Adam admin admin Agus, Al Ihksan Aldri Frinaldi Alfina Baharuddin Alwi, Muhammad Khidri Amir, Haeril Amran Razak Andaresta, Ayu Andi Aliani Aliuddin Andi Alim, Andi Andi Dewi Sartika Andi Dindha Batari R. Andi Dindha Batari Ramadhani Andi Hanifah Muslimah Andi Nur Aida Hafdia Andi Nurlinda Andi Ratu Tria Syahrani Andi Ridwan Jalal Andi Tenri Anggraeni, Susanti Dwi Apriana Toding Aris, Arni AR Arlin Adam, Arlin Arman Arman Arman Arman Arman Arman Arni Risqiani Arni Rizqiani Rusydi Arniati Santi Bau Mila Tunnizha Besse Dwy Ayu Paramitha Dai Burhan Bungin Chaeruddin Hasan Dian Indraswati Dwi Islami Amir Rumae Dwi Islami Amir Rumae Dwi Murty Wardani Hermanzah E Ernawati Edy Edy Een Kurnaesih Een Kurnaisih Een Kurnaisih Ella Andayanie Endian, Nurmala Fairus Prihatin Idris Fairuz Prihatin Idris Fardin, Mr. Fatma Afrianty Gobel Fatmah Afrianty Gobel Fila, Ikda Haerati Haerati Haeril Amir Haeruddin Haeruddin Haeruddin Haeruddin Haeruddin, Haeruddin Haeruddin Hamzah, Wardiah Harbia, Harbia Harbia, Harbia Hariani Hariani, Hariani Harismaswati Bahtiar Harismawati Bahtiar Harismawati Bahtiar Harpiana Rahman Hartati Baharuddin Hasnidar Hasriwiani Habo Abbas Hermanzah, Dwi Murty Wardani Hijrah Hijrah Idris, Fairus Prihatin Indah Sari Indri Ardiyanti Saleh Intan Deasy Agmaitry Jayanti, Jayanti Kamilatin, Siska Kasman, Nirmalasari Khaldun, Syamsu Khalid, Sajidah Hardiyanti Laksono Trisnantoro M Mirna M Rizal Payapo Madin, Hermadin Hermadin Maisarah Basarang Marliana Marliana, Marliana Marwono Marwono Marwono, Marwono Masjidi, Iriani Merissa Laora Heryanto Minarti S., Asriani Mira M Radjung Muh. Alif Reski Muh. Arfah Muh. Khidri Alwi Muh. Multazam, Andi Muh. Pasca Rivaldi Muhamad Ikhsan Muhammad Alif Reski Muhammad Asri Muhammad Ikhtiar Muhammad Ikhtiar Muhammad Kidri Alwi Muhd. Firmansyah Multazam, Andi Munifah Yusriah A. Munifah Yusriah Arief N Nurbaya N Nurhaedar J Nunung Aryanti Arsyad Nur Ghani Nur Inda Rahmayani Nur Sri Widyastuti Nur Sri Widyastuti Nur Ulmy Mahmud Nurfadhilah Pratiwi Nurgahayu Nurmalia, Eka Nursafitri, Nadia Nurul Annisa NURUL ANNISA Nurul Azizah Nurwahdaniar Syahrul Nurwahdaniar Syahrul Putri Utami, Putri RATNA SARI Reina Renita Irawan Relawati Relawati Reski Elvinasari Reski, Muhammad Alif Rhadiathul Islamiah Rifdah Mufiidah Rusli Riri Rino Rino Riski Dwiputri A. RR. Ella Evrita Hestiandari S., Ikhram Hardi Safitri, Nadia Nur Sajidah Hardiyanti Khalid Samsualam, Samsualam Septiyanti Septiyanti Septiyanti, Septiyanti Sitti Patimah Soviyati, Evie Sri Astuty Mashuri Sri Nurjianti Srimulyawati, Tia ST Arifah ST. Nurul Izzah Habibarraahman ST. Nurul Izzah Habibarrahman Sudirman Sufatmiaty Sufatmiaty Suharni A. Fachrin Sulymbona, Nurdewi Sumiaty Sumiaty Sundari Sundari Suriah Suriah Sutriani Tahir, Santiani Tawali, Abu Bakar Tria Syahrani, Andi Ratu Umaya, Mira Weli Weli Wildia Nanlohy Wildia Nanlohy William Tasidjawa William Tasidjawa Wulan Lindasari, Sri Yona Septina Yulanda, Anda Yusriani, Yusriani Zulfikar, Andi Muh