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Wiriansya, Edward Pandu
Universitas Muslim Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Journal : Green Medical Journal

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The Profile of Lung Adenocarcinoma Patients with Positive EGFR Mutation Pandu Wiriansya, Edward; Ainun; Ratu, Puspa; Muhammad Reza Cesarian Noor, Andi
Green Medical Journal Vol 2 No 1 April (2020): Green Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (372.823 KB) | DOI: 10.33096/gmj.v2i1.37

Abstract

Background: The high mortality rate in pulmonary carcinoma is a problem encountered in various countries, including Indonesia. According to WHO, there are 2.09 million people affected by lung cancer and 1.76 million deaths due to lung cancer worldwide. This study was aimed to determine the profile of lung adenocarcinoma patients with positive EGFR mutation. Methods: The study was descriptive study with cross-sectional approach using secondary data obtained from medical records of lung adenocarcinoma patients. Results: The present study revealed that lung adenocarcinoma was found higher in patients with age >40 years old (93.9%) compared to those with age <40 years old. It was also higher in male (66.7%) than in female patients. Most patient with lung adenocarcinoma were at the IIIB stage (42.4%). It was also reported that higher cases was found in patients with history of smoking more than 15 years (42.4%). Hemoptoe was the most reported clinical symptoms in patients with lung adenocarcinoma (87.9%). Lung adenocarcinoma was also observed higher in patients without family history of pulmonary adenocarcinoma (81.8%). Seventeen of 33 EGFR mutations (51.5%) were observed in exon 19 and fourteen (48.5%) were in exon 21. Conclusion: The most common EGFR mutation lung adenocarcinoma was observed in exon 19.
Co-Authors Abdi, Dian Amelia Agung Dirgantara Ahmad Fahd Alifian Ainun Andi Muhammad Luthfi Parewangi Andi Sitti Fahirah Andi Tenri Sanna Andi Tiara Salengke Adam Anggita, Dwi Anna Sari Dewi Arina Fathiyyah Armanto Makmun Arni Isnaini Arfah Asrini Safitri Asrini Safitri Asrini Safitri Dewi Rahman Dian Amelia Abdi Dinda Permatasari, Dinda Dzul Ikram Eka Yanti, Kartini Eny Arlini Wello Febie Irsandy Fendy Dwimartyono Fitrah Ahmad, Izhar Irawaty Djaharuddin Irsandy, Febie Kasim, Sharen Laksmi Wulandari Lisa Yuniaty M. Hamsah Muh Anugrah Ramadhan Muhamad Ilhamsyah Dandung Muhammad Mursyid Muhammad Naufal Zuhair Muhammad Reza Cesarian Noor, Andi Mustafa, Maulana Saggaf Mutmainnah Musa, Inna Nasrudin Andi Mappaware Noor, Andi Muhammad Reza Cesaria Nurfachanti Fattah Prema Hapsari Hidayati Purnamasyani s, Andi Husni Esa Puspa Ratu, Andi Rachmat Faisal Syamsu Rachmat Faisal Syamsu Rahman, Titin Suhartina Rahmawati Rahmawati Rahmawati, Rahmawati Rasfayanah Rasfayanah Ratu, Andi Puspa Ratu, Puspa Santriani Hadi Shofiyah Latief Sidrah Darma Siti Nurisyah Sri Wahyu Sri Wahyuni Gayatri Susilo, Wawan Syamsu Rijal Syamsu Rijal Utami Haerunnisya, Putri Utomo Andi Pangnguriseng wahyuni wahyuni Wulan Purnamasyani Yusriani Mangarengi Yusriani Mangerangi Zulfah Midah Zulfahmidah Zulfitriani Murfat Zulfiyah Surdam