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All Journal EKSAKTA: Journal of Sciences and Data Analysis Jurnal Ilmiah Manuntung Dinamisia: Jurnal Pengabdian Kepada Masyarakat JURNAL KESEHATAN PERINTIS Jurnal Ilmu Kefarmasian Indonesia Jurnal Farmagazine Journal of Pharmaceutical and Health Research Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Journal of Experimental and Clinical Pharmacy (JECP) Jurnal IPTEK Bagi Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan International Journal Mathla'ul Anwar of Halal Issues Jurnal Abdi Masyarakat Kita Sciences of Pharmacy Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Journal of Global Pharma Technology Jurnal Pengabdian Pada Masyarakat Jurnal Ilmiah Kesehatan Delima Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Stiani, Sofi Nurmay
STIKes Salsabila Serang
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Journal : EKSAKTA: Journal of Sciences and Data Analysis

 1 
Determination of Total Flavonoid Content and Characterization of Nanoparticles of Kecombrang Leaf Extract (Etlingera elatior (Jack) R.M.Sm.) Hayati, Farida; Sofi Nurmay Stiani; Renditya Ismiyati
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 6, ISSUE 1, April 2025
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/EKSAKTA.vol6.iss1.art4

Abstract

Kecombrang (Etlingera elatior (Jack) R.M.Sm.) is one of Indonesia's potential plants that contain such bioactive compounds as polyphenols, alkaloids, flavonoids, steroids, saponins, and essential oils. This study aims to determine the total flavonoid content of kecombrang leaf extract. It also defines the characteristics of the nanoparticles of kecombrang leaf extract. Kecombrang leaves were extracted through maceration. The determination of the total flavonoid content by spectrophotometry used quercetin as a comparison. The synthesis of nanoparticles used ionic gelation with 0.1% sodium alginate and 0.01% calcium chloride crosslinkers. The characteristic parameters of the nanoparticles of kecombrang leaf extract included the visual, transmittance, adsorption efficiency, particle size distribution, polydispersity index, and zeta potential. The yield value was 46.55%. The total flavonoid content was 88.11 mgQE/g with a regression standard curve Y = 0.1022x + 0.0745 and correlation coefficient (r) = 0.9922. The nanoparticle solution provided a clear visual with a particle size and PI of 108.2 nm and 0.311, a transmittance and adsorption efficiency of 94.76% and 93.76%, and a zeta potential of -36 mV. The total flavonoid content was 88.11 mgQE/g. The nanoparticle solution of kecombrang leaf extract has the characteristics that qualify as a nanoparticle preparation.
Co-Authors Achmad Fudholi Ade Anwar Ade Apriliani Adini, Syilvi Afifah Nur Shobah Agus Sulaeman Alfarizqi, Asep Salman Anwar, Ade Apriliani, Ade Audy Nursifa'atun Aufalya Wibirezkina Aulia, Ayu Cahya, Wulan Chairani, Farahdina Deya Adiby Nabillah Elfrida Ratnawati endah, endah Endi Muchyar Eneng Elda Ernawati Ernawati, Eneng Elda Fahlevy, Muhamad Ichsan Fajrin Noviyanto Fajrin Noviyanto, Fajrin Ferdiyansyah, Ferdiyansyah Fifih Lutfiyah Ghina Annufus Harpan, Andri Hayati, Farida Herawati, Fera Ismiyati, Renditya Junaedi, Candra Kelutur, Faruk Jayanto Kholifah, Eva Kuncoro, Banu Leni Halimatusyadiah Lidiah, Mae Lutfiyah, Fifih Maharani, Zahra Citra Masfuah, Imas Megawati, Sefi Mohammad Rizal Mohammad Rizal, Mohammad Nabillah, Deya Adiby Nasiti, Febriane Dwi Neneng Nasliah Nita Rusdiana S.Farm., M.Sc, Apt Nurani, Agnes Wieanita Nurhikmah, Ihda Nurul Fitri, Nabila Oktaviana Hadi, Agriyaningsih Pratiwi, Linda Rani Pratiwi, Rossi Putri, Nabila Septiani Rahmawida Putri Renditya Ismiyati Renditya Ismiyati Rini Rumantir Rizkiana, Muhammad Dinta Rustiyani, Risa Sabilla, Aliffia Nur Salsabillah, Audy Nursifa'atun Satibi . Seira, Trisya Septina Sumantri, Aulia Shobah, Afifah Nur Siska Purnama Sari Siti Lailatu Zahroh Siti Marina Subchan, Mohamad Suci Nurainun Sudarto, Teguh Sumarlin US Sylvianti Maharani Udin, Baha US, Sumarlin Wibirezkina, Aufalya Yusransyah Yusransyah Yusransyah Yusransyah Yusransyah, Yusransyah