Articles
Effectiveness of Erythropoetin Alpha and Eryhtropoetin Beta in Patients With End-Stage Kidney Disease with Anemia Undergoing Hemodialysis: A Meta-Analysis Study
Sunur, Vincentius William;
Sulistio, Timothy;
Adisyahputra, Vega;
Safira, Vita;
Adiwinoto, Ronald Pratama;
Setyawan, Yuswanto
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.26911/theijmed.2024.9.4.749
Background and Objectives: One of the causes of anemia in ESRD (End Stage Renal Disease) is due to lack of erythropoietin (EPO) production. The use of short-lived ESA preparations such as Erytrhopoietin alpha and Erytrhopoietin beta still differs in opinion about the effectiveness between the two ESA agents. So the purpose of this study is to review the findings from various studies to provide a better understanding of the effectiveness of the use of ESA. Method The results of the study sought were the effectiveness of erythropoietin alpha and erythropoietin beta which were assessed by the hemoglobin levels in the study. This study uses a meta-analysis design in accordance with the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Data search using PUBMED, ResearchGate, and ScienceDirect databases Results A total of 458 studies were identified through database sources. After adjusting for inclusion and exclusion criteria, there were 6 studies to be reviewed in a meta-analysis with a total of 220 patients given erythropoietin alpha therapy and 227 patients given erythropoietin beta therapy. The results of the meta-analysis showed that there was no significant difference in the erythropoietin alpha and erythropoietin beta groups after 1 month of therapy (P = 0.20, MD = 0.16, 95% CI [ -0.57, 1.17], I2 = 0% [P = 0.56]), nor after 3 months of therapy (P = 0.19, MD = -0.27, 95% CI [-0.68, 0.13], I2 = 0%, [P = 0.58]) Conclusions There was no significant difference between the effectiveness of erythropoetin alpha and erythropoetin beta in increasing patients' hemoglobin levels. These two ESA agents are effective in increasing hemoglobin levels in ESRD patients.
Analisis Perbandingan Kadar Hemoglobin dan Eritrosit pada Ibu Hamil Normal dengan Ibu Hamil Kekurangan Energi Kronis (KEK) di Kota Surabaya dan Sumenep
Idarto, Areta;
Siahaan, Salmon Charles;
Lukas, Dwi Lily;
Setyawan, Yuswanto;
Tannus, Ferdinand Aprianto
ANATOMICA MEDICAL JOURNAL | AMJ Vol 7, No 3 (2024)
Publisher : Universitas Muhammadiyah Sumatera Utara
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.30596/amj.v7i3.18905
Menurut data dari Kementerian Kesehatan Indonesia (2020), dari total 4.656.382 ibu hamil di seluruh provinsi Indonesia, sebanyak 451.350 di antaranya memiliki risiko Kekurangan Energi Kronis (KEK), mewakili persentase sebesar 9,7%. Di antara ibu hamil, 59,5% merupakan primigravida yang mengalami KEK, 56% merupakan ibu hamil yang bekerja, dan 88% merupakan ibu hamil dengan usia berisiko (20-35 tahun) yang mengalami KEK. Tujuan: untuk menganalisis antara kadar Hb dan jumlah eritrosit antara ibu hamil normal dan ibu hamil yang mengalami KEK dan korelasi antar variabel. Metode: eksperimental dengan desain penelitian epidemiologi analitik dengan pendekatan cross-sectional, menggunakan teknik non-probability sampling dengan quota dan purposive sampling, dengan jumlah sampel sebanyak 30 orang. Hasil: Analisis penelitian menunjukkan bahwa variabel gravida memiliki distribusi normal pada kedua kelompok ibu hamil normal dan yang mengalami KEK. Data usia dan gravida menunjukkan homogenitas. Terdapat perbedaan yang signifikan dalam kadar Hb dan jumlah eritrosit antara ibu hamil normal dan ibu hamil yang mengalami KEK. Selain itu, terdapat korelasi yang signifikan antara kadar Hb dan jumlah eritrosit. Kesimpulan: terdapat perbedaan yang signifikan dalam kadar Hb dan jumlah eritrosit antara ibu hamil normal dan ibu hamil yang mengalami KEK (nilai p 0,001).Kata Kunci: KEK, Hb, Eritrosit
Hubungan durasi tidur dan penyakit jantung koroner pada pria usia 40 tahun ke atas
Setyawan, Yuswanto
Holistik Jurnal Kesehatan Vol. 19 No. 1 (2025): Volume 19 Nomor 1
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.33024/hjk.v19i1.801
Background: Men aged 40 years and over tend to have difficulty getting enough sleep, this is associated with greater responsibility, hormonal changes, stress levels and overthinking. Unknowingly, sleep duration of less than 8 hours results in various diseases, one of which is coronary heart disease. Purpose: To test the correlation between sleep duration and coronary heart disease in men aged 40 years and over. Method: This study design uses descriptive cross-sectional analysis with the help of SPSS software which will be tested for univariate analysis and spearman correlation test using 107 respondents. The test was conducted with the aim of finding out what symptoms are most dominant and the correlation between variables. Results: The correlation coefficient value of r count 0.611 shows a positive value. So the worse the sleep pattern (≤ 6 hours) the more the incidence of Coronary Heart Disease will increase. Conclusion: Men aged 40 years and over who sleep <6 hours per day can increase the risk of coronary heart disease with the most common symptom being Angina Pectoris or “choking chest” by 85%. The relationship between sleep duration and coronary heart disease is significant. This shows that the lower the sleep duration, the higher the risk of coronary heart disease. Keywords: Coronary Heart Disease; Men Aged 40 Years or Older; Sleep Duration. Pendahuluan: Pria dengan usia 40 tahun keatas cenderung kesulitan mendapatkan tidur yang cukup hal ini dikaitkan dengan tanggung jawab yang lebih besar, perubahan hormonal, tingkat stress dan overthinking. Tanpa disadari durasi tidur yang kurang dari 8 jam mengakibatkan datangnya berbagai macam penyakit salah satunya jantung koroner. Tujuan: Untuk menguji korelasi antara durasi tidur dan penyakit jantung koroner pada pria usia 40 tahun keatas. Metode: Desain penelitian ini menggunakan analisis deskriptif cross sectional dengan bantuan software SPSS yang akan diuji analisis univariat dan uji korelasi spearman dengan menggunakan 107 responden. Uji tersebut dilakukan dengan tujuan mengetahui gejala apa yang paling dominan dan korelasi antar variabel. Hasil: Nilai koefisien korelasi r hitung 0,611 menunjukkan nilai positif. Jadi semakin buruk pola tidur (≤ 6 jam) maka kejadian Penyakit Jantung Koroner akan semakin meningkat. Simpulan: Pria usia 40 tahun keatas yang durasi tidur < 6 jam perhari dapat meningkatkan risiko penyakit jantung koroner dengan gejala yang paling sering dialami yaitu Angina Pectoris atau “dada yang tercekik” sebesar 85%. Hubungan durasi tidur dan penyakit jantung koroner signifikan. Hal ini menunjukkan bahwa semakin berkurang durasi tidur, maka semakin meningkat risiko jantung koroner. Kata Kunci: Durasi Tidur; Jantung Koroner; Pria 40 Tahun Keatas.
CONSUMPTION OF SOFT DRINKS IS ASSOCIATED WITH DIABETES MELLITUS IN TEENAGERS
Setyawan, Yuswanto
HEARTY Vol 13 No 2 (2025): APRIL
Publisher : Fakultas Ilmu Kesehatan, Universitas Ibn Khaldun, Bogor
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.32832/hearty.v13i2.19299
Consumption of drinks containing high sugar causes diabetes mellitus. Diabetes causes insulin resistance, defined as where normal or increased insulin levels result in a weakened biological response. Classically, this refers to impaired sensitivity to insulin-mediated glucose disposal. Research with a cross-sectional model using adolescents as research subjects Regarding soft drinks. The population in this study were adolescents aged 12-24 years according to WHO criteria. The sample used in this study was 118 respondents. The sampling technique used quota sampling. Soft drinks increase the incidence of diabetes mellitus compared to those who do not consume soft drinks, such as Tingling or numbness in the hands and feet, as many as 61.9% of teenager feel these symptoms. Furthermore, teenager also often feel wounds that do not heal as many as 59.3% and Constant fatigue as many as 57.6%. For further researchers, it is hoped that they will examine the eating patterns of adolescents associated with the consumption of carbonated drinks and diabetes mellitus.
Correlation of Seblak Consumption to Hypertension in Generation Z: Korelasi Konsumsi Seblak Terhadap Hipertensi Pada Generasi Z
Setyawan, Yuswanto
Jurnal Ilmiah Kesehatan Vol 17 No 1 (2025): Jurnal Ilmiah Kesehatan
Publisher : Universitas Mohammad Husni Thamrin
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.37012/jik.v17i1.2528
This research aims to find out how spicy eating (seblak) is related to hypertension in generation Z. The research method used was cross-sectional with a descriptive model analyzed using SPSS with the chi-square test and Spearman correlation test. The population is all generation Z who consume seblak in Sidoarjo Regency, a total sample of 100 consisting of 50 women and 50 men. The results of this research are that based on research and analysis carried out on generation Z consumption of seblak and hypertension, it was found that out of 100 people who consumed seblak, 50 men and 50 women related to the tendency to experience hypertension, women were accompanied by the most symptoms, namely dizziness with a percentage of 19-28% and on average generation Z did not know if they had hypertension, the most symptom was heart palpitations with a percentage of 23-28%. This research shows that consuming seblak can increase the risk of hypertension in generation Z, especially women. As a suggestion for further research, it is hoped that research will focus more on UPF foods or ultra-processed foods contained in spicy foods and their impact on generation Z. Keywords: Spicy Food, Hypertension, Generation Z
The Effect of Industrial Noise Exposure on Hypertension Incidence Among Factory Workers in Surabaya
Sholihah, Puput Mar'atus;
Setyawan, Yuswanto
Jurnal Ilmiah Kesehatan Vol 17 No 1 (2025): Jurnal Ilmiah Kesehatan
Publisher : Universitas Mohammad Husni Thamrin
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.37012/jik.v17i1.2647
In Surabaya, as one of Indonesia's industrial centers, many factory workers are exposed to high noise levels daily. However, specific data on the relationship between industrial noise exposure and hypertension incidence among factory workers in Surabaya is still limited. This study aims to assess the association between industrial noise exposure and hypertension among factory workers in Surabaya. This study aims to assess the association between industrial noise exposure and hypertension among factory workers in Surabaya. The collected data were analyzed using appropriate statistical tests, such as the Chi-Square test and Spearman correlation. The Spearman correlation analysis indicates that industrial noise exposure contributes to a 62% increase in the incidence of hypertension among factory workers in Surabaya, particularly affecting women at a higher rate than men. Higher noise levels correlate with a greater risk of developing hypertension. Noise from factory machinery also increases hypertension risks more significantly among female workers and employees over 40 years old, regardless of gender. Keywords; Industrial noise exposure; Hypertension; Factory workers
SARCOPENIA DAN TINGKAT DEPRESI PADA LANSIA DI SURABAYA
Setyawan, Yuswanto
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 1 (2025): APRIL 2025
Publisher : Universitas Pahlawan
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.31004/prepotif.v9i1.43722
Sarcopenia adalah penyakit karena keterbatasan fisik yang dialami lansia yang erat kaitannya dengan resiko jatuh, resiko jatuh ini juga berdampak pada keberlangsungan hidup lansia yang mampu meningkatkan depresi. Dari fenomena diatas rumusan masalah penelitian yaitu apakah Sarcopenia berhubungan dengan depresi pada lansia. Tujuan penelitian ini adalah untuk mengetahui penyebab depresi apa yang banyak dialami lansia yang mengidap Sarcopenia. Kebaruan penelitian ini yaitu lokasi penelitian hanya dilakukan di 1 kota Surabaya. Metode penelitian ini cross sectional deskriptif.. Data diperoleh selama 2 bulan pada bulan januari 2025-februari 2025 yang berlokasi di Surabaya. Sarcopenia tidak hanya berkontribusi terhadap penurunan fungsi fisik tetapi juga terhadap kemungkinan jatuh dan patah tulang yang lebih tinggi. Menurut meta-analisis, prevalensi Sarcopenia pada orang di bawah usia 60 berkisar antara 8 hingga 36% dan pada orang di atas 60 dari 10 hingga 27%; prevalensi Sarcopenia berat ditemukan sekitar 2% dan 9%. Oleh karena itu, identifikasi faktor risiko yang terkait dengan Sarcopenia di antara orang dewasa yang lebih tua dan pengurangan tingkat kejadian Sarcopenia melalui intervensi sangat penting. Populasi adalah lansia di Surabaya. Sampel penelitian yaitu lansia yang menderita penyakit Sarcopenia , sampel didapat menggunakan kuota sampling dengan total 123 responden. Hubungan sarcopenia terhadap tingkat depresi pada lansia di Surabaya memiliki nilai koefisien korelasi r hitung 0.521 tergolong kategori Sedang, dan signifikansi 0.000 lebih kecil dari 0.05. Sarcopenia terbukti secara signifikan berhubungan dengan depresi yang diderita oleh lansia artinya apabila semakin lama dan parah Sarcopenia maka meningkatkan gejala depresi pada lansia di Surabaya.
Gangguan Makan Terkait Dengan Hipoglikemia Pada Wanita Usia 40 Tahun Ke Atas
Setyawan, Yuswanto
An-Nadaa: Jurnal Kesehatan Masyarakat (e-Journal) Vol 12, No 1 (2025): AN-NADAA JURNAL KESEHATAN MASYARAKAT (JUNI)
Publisher : Universitas Islam Kalimantan Muhammad Arsyad Al Banjari Banjarmasin
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.31602/ann.v12i1.18677
Hipoglikemia merupakan komplikasi diabetes. namun gangguan makan dalam pemilihan konsumsi makanan dapat meningkatkan gejala hipoglikemia. Tujuan penelitian ini yaitu menambah literatus khusus tentang hipoglikemia serta gangguan makan. Desain penelitian ini merupakan cross-sectional deskriptif. Variabel dependen yaitu hipoglikemia dan faktor independent adalah Gangguan Makan. Populasi penelitian ini adalah wanita menderita diabetes mellitus 2. Sampel yang digunakan yaitu 105 responden dengan karakteristik berusia 40 tahun keatas dan berdomisili di Jawa Timur. Pada penelitian ini menggunakan kuota sampling, untuk selanjutnya dianalisis menggunakan SPSS terbaru 30 dan menggunakan uji univariat dan uji korelasi spearman. Gangguan makan terbukti secara signifikan berpengaruh pada kejadian hipoglikemia pada wanita usia 40 tahun ke atas. Artinya semakin wanita usia 40 tahun keatas sering mengalami gangguan makan termasuk makan telat, makan tidak 3x, tidak mengonsumsi sayur buah dan protein maka dapat meningkatkan kejadian hipoglikemia sebanyak 49,3%. Saran bagi penelitian selanjutnya dapat menggunakan kuesioner The Yale Food Addiction Scale (YFAS 2.0) sebagai kuesioner. Kata Kunci: Gangguan Makan; Hipoglikemia; Komplikasi Diabetes; Wanita
Relationship between High Fat Diet and Risk of Hyperlipidaemia in Primary School Children in Surabaya
Iriane, Vincentia Maria;
Setyawan, Yuswanto
Jurnal teknologi Kesehatan Borneo Vol 6 No 1 (2025): Jurnal teknologi Kesehatan Borneo
Publisher : POLTEKKES KEMENKES PONTIANAK
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.30602/jtkb.v6i1.407
The prevalence of hyperlipidaemia in children in Indonesia is 84.7%, which is very high. Although the health consequences of overweight in children are still poorly studied compared to adults, overweight in children has been consistently reported as a major risk factor for future metabolic conditions, such as type 2 diabetes mellitus, metabolic syndrome, cardiovascular disease, and some cancers. This study focuses specifically on primary school children only and the research location is in Surabaya. The purpose of this study was to analyse the relationship between the level of fat consumption and blood lipid levels in primary school children. This research method is cross-sectional. In this study, data were collected using the Modified Food Frequency Questionnaire (FFQ) and measurement of total cholesterol, LDL, HDL, and triglyceride levels through blood samples and analysed using chi square test and spearman correlation using SPSS Software. The results found that elementary school children who rarely consume high-fibre foods have a 6x greater risk of hyperlipidemia than in the category of frequent consumption of high-fibre foods. Suggestions for future research are expected to analyse hyperlipidemia in children and be associated with gender in elementary school students in order to know more in-depth differences.
Acute Kidney Injury (AKI) Pasca Primary Coronary Intervention (PCI) pada Pasien STEMI
Gunawan, Erik Jaya;
Isnaini, Isnaini;
Siahaan, Salmon Charles P. T.;
Setyawan, Yuswanto;
Ritunga, Imelda
Nommensen Journal of Medicine Vol 10 No 1 (2024): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
DOI: 10.36655/njm.v10i1.1376
Background: Treating STEMI with PCI not only has a positive impact on patients, but also the risk of complications. A complication that can occur is AKI. The aim of this case report is to increase clinician awareness by analyzing the risk of AKI after PCI in order to reduce patient morbidity and mortality rates. Case: A 58-years old-man, with a history of diabetes mellitus, dyslipidemia, and a previous heart attack, came to the emergency department because of chest pain. The patient experienced STEMI and received fibrinolytic therapy. After 3 days of treatment, the condition worsened and the patient experienced shortness of breath (pulmonary edema). The patient was referred to RSUD Dr. M. Soewandhie Surabaya to undergo PCI. Two days after PCI, there were clinical signs of AKI. The patient was prepared for Renal Replacement Therapy (RRT), but the patient experienced cardiac arrest and was declared dead. Discussion: AKI after PCI involves various complex mechanisms. Several factors that can increase the probability of AKI after PCI in this case are a history of diabetes mellitus, previous decline in kidney function, and pulmonary edema. Technique factors such as transfemoral PCI and the amount of contrast volume used also have an influence on the incidence of AKI after PCI and need to be studied further. Risk factors in patients can be used to determine clinical scores, such as the Mehran, ADVANCIS, or ACEF-MDRD scores to predict the probability of AKI after PCI. Conclusion: AKI after PCI is a frequent complication and calculations using clinical scores can be applied to predict this event.