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All Journal JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE As-syifaa Jurnal Farmasi BIOEDUSCIENCE Martabe : Jurnal Pengabdian Kepada Masyarakat JPSCR : Journal of Pharmaceutical Science and Clinical Research PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Jurnal Farmamedika (Pharmamedica Journal) Jurnal Pengabdian Harapan Ibu (JPHI) Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Farmagazine Alauddin Journal of Mathematics Education (AJME) Jurnal Kesehatan Masyarakat Mulawarman (JKMM) Jurnal Insan Farmasi Indonesia Jurnal Kesehatan Tambusai Jurnal Farmasi Indonesian Journal of Pharmaceutical Education KESANS : International Journal of Health and Science PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Cerdika: Jurnal Ilmiah Indonesia Jurnal Pengabdian Harapan Ibu (JPHI) Jurnal Multidisiplin Indonesia Radinka Journal of Health Science Jurnal Abdimas Kesehatan Jurnal Akademika Baiturrahim Jambi Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Andriani, Medi
Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi
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Uji Efektivitas Daun Sirih Merah (Piper crocatum) Terhadap Penurunan Kadar Gula Darah Mencit Putih Jantan (Mus musculus) yang Diinduksi Aloksan Andriani, Medi; Putra, Rizki Yulion; Rosyta, Dini Galoh
BIOEDUSCIENCE Vol 8 No 2 (2024): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/13320

Abstract

Background: Hyperglycemia is when blood sugar levels increase excessively from normal sugar levels. High blood sugar levels in the body that exceed normal limits occur when the random blood sugar test value is ≥200 mg/dl and fasting blood sugar is ≥126 mg/dl. One natural ingredient known to lower blood sugar levels is red betel leaf (Piper crocatum). Methods: The method used in this research is the extraction and fractionation of n-hexane, ethyl acetate fraction, n-butanol fraction, and residual water fraction. Results: The results of research that has been carried out by giving fractionated n-butanol is effective in reducing blood sugar levels in male white mice (Mus musculus) that have been induced by alloxan. Conclusions: The positive group was obtained, and the results of administering the n-butanol fraction at a dose of 100 mg/KgBW affected reducing the blood sugar levels of male mice (Mus musculus) which had been induced by alloxan on days 2, 4, and 6, which decreased the most.
SINTESIS SENYAWA DIMETILTIMAH(IV) N-BENZILMETILDITIOKARBAMAT DAN UJI ANTIBAKTERI TERHADAP Salmonella typhi DAN Staphylococcus epidermidis Sanuddin, Mukhlis; Andriani, Medi; Yasril, Farih Rahma
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/fx3d9c23

Abstract

Antibacterial can inhibit growth or kill microorganisms. The purpose of this study is to synthesize and determine the antibacterial activity of the dimethyltin(IV) N-benzylmethylditiocarbamate. The research method used in this study is an experimental method. The compounds characterized using FTIR, 1H-NMR, 13C-NMR, compounds analyzed using FTIR obtained groups (C-H) 2912.51 cm-1, (C-N) 1192.01 cm-1, (C=S) 773.46 cm-1, (Sn-S) 360.69 cm-1, (Sn-C) 561.29 cm-1, (C-C) 1078.21 cm-1, the results of analysis from the 1H-NMR test were obtained 0.6552-0.8861 ppm (CH3), 2.5843-2.6479 ppm (CH2), and 7.0888-7.4345 ppm (Aromatic). The results of the analysis from the 13C-NMR test were obtained 4.1023-7.6992 ppm (CH3), 46.6439 ppm (CH2), 59.9685 ppm (C-N), 127-6009-135.1784 ppm (Caromatic), and 201.4111 (C-S2). Then the antibacterial activity test was carried out by the disc paper method with concentrations of 50 ppm, 60 ppm, and 70 ppm with the results of testing antibacterial activity with a concentration of 70 ppm resulting in the largest inhibitory zone with a strong category in Salmonella typhi 17.81 mm and Staphylococcus epidermidis 21.96 mm with a very strong category. Conclusion The compound dimethyltin(IV) N-benzylmethyldithiokarbate was successfully synthesized and formed a complex compound structure and has activity as an antibacterial agent with a very strong category.
Pemberantasan Stunting dan Penatalaksanaan Permasalahan Kesehatan Masyarakat Cerdas Andriani, Medi; Putri, Kiki Ananda; Maharani, Juliantika; Hidayati, Atriani; Ibriyanti, Silda; Shabirah, Athayyah; Lina, Ade Okta; Cupa Munti, Putri Delina; Sandi, Putri Lara
Jurnal Abdimas Kesehatan (JAK) Vol. 7 No. 1 (2025): Januari
Publisher : Universitas Baiturrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36565/jak.v7i1.768

Abstract

Stunting is a growth and development disorder in children, not only inhibiting physical growth but also other growth processes such as mental, cognitive, and intellectual development. Stunting is caused by long-term malnutrition that can occur from conception to the age of 24 months. In Indonesia, the prevalence of stunting is projected to decrease by 2.8% to 21.6% in 2022. Based on data from the Batanghari Regency Health Office, the number of young children suffering from stunting has increased compared to 2021. The results of the 2022 Indonesian Child Nutrition Survey (SDGBI) revealed that the stunting rate in Batanghari reached 26.3%, making Batanghari Regency the district/city with the highest stunting rate in Jambi Province. The purpose of this study is to increase public understanding of what stunting is, its causes, short-term and long-term risks of stunting, and how to overcome the impact of stunting. The method carried out is direct counseling to the people of Tanjung Putra village, Mersam, Batang Hari. The results obtained are 80% of the people of Tanjung Putra village know about stunting.
PROFIL PENANGANAN SWAMEDIKASI DEMAM ANAK SETELAH ISU PENARIKAN OBAT SIRUP DI DESA PONDOK MEJA TAHUN 2022 Saputri, Ghina Nabilla Dwi; Dewi, Rasmala; Andriani, Medi
Jurnal Farmamedika (Pharmamedika Journal) Vol 10 No 1 (2025): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v10i1.429

Abstract

Demam adalah kondisi dimana suhu tubuh mencapai ≥ 37,5°C. Demam merupakan suatu keadaan gejala yang menandakan bahwa tubuh terinfeksi ringan hingga berat oleh virus, bakteri atau parasit. Swamedikasi adalah upaya masyarakat untuk mengobati dirinya sendiri. Tujuan penelitian ini untuk mengetahui tingkat pengetahuan masyarakat mengenai swamedikasi demam pada anak dan perilaku masyarakat mengenai isu penarikan obat sirup anak oleh BPOM di Desa Pondok Meja. Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross sectional. Sampel dalam penelitian ini adalah ibu di Desa Pondok Meja yang memiliki balita (0 – 5 tahun) atau anak (5 - 11 tahun) dan pernah melakukan swamedikasi demam. Hasil yang diperoleh sebanyak 100% responden berjenis kelamin perempuan dengan rentang usia 30-42 terbanyak yaitu 60%, pendidikan terbanyak SMA 35% dan Pekerjaan terbanyak Ibu Rumah Tangga 58,33%. Kesimpulan penelitian ini dari 120 responden, (97,50%) menggunakan paracetamol untuk obat swamedikasi demam anak, (86,67%) menggunakan obat dengan bentuk sediaan sirup, (73,33%) mengatakan aturan pakai obat adalah 3 x sehari setelah makan, (79,17%) menggunakan thermometer untuk mengetahui bahwa anak sedang demam, (65,83 %) memilih menggunakan air hangat untuk mengompres anak yang sedang demam, (75%) terlebih dulu membaca petunjuk pada kemasan obat sebelum memberikannya kepada anak yang demam, (100%) mengetahui berita penarikan obat sirup oleh BPOM dan (38,33%) mendapatkan informasi melalui televisi, (90,83%) mengetahui penyakit yang diduga sebagai alasan penarikan obat sirup oleh BPOM yaitu Gagal Ginjal Akut, (99,17%) memilih apotek untuk tempat membeli obat swamedikasi, (43,33%) memilih membawa anak ke dokter praktek ketika dalam 3 hari swamedikasi demam anak tidak juga mereda dan (65,83%) tetap menggunakan obat setelah adanya berita penarikan obat sirup oleh BPOM namun dalam bentuk sediaan puyer.
Sub-Acute Toxicity Test of Red Betel Leaves (Piper crocatum) on Liver Function in Male White Mice (Mus musculus) Using SGPT Test Andriani, Medi; Putra, Rizky Yulion; Asnadewi, Veni
BIOEDUSCIENCE Vol 8 No 3 (2024): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/14640

Abstract

Background: This research aims to investigate the sub-acute toxicity of red betel leaves (Piper crocatum) on liver function in male white mice (Mus musculus) using a serum glutamic-pyruvic transaminase (SGPT) test on a clinical photometer instrument. Methods: This research aims to investigate the sub-acute toxicity of red betel leaves (Piper crocatum) on liver function in male white mice (Mus musculus) using a test serum Glutamic Pyruvic Transaminase (SGPT) assay on a clinical photometer instrument. In this study, an experimental method was employed using a randomized block design, with 72 mice serving as research subjects and divided into eight treatment groups. Group 1 was given 0.5% Na CMC, group 2 as a positive control; group 3 was given a comparison of metformin; group 4 was given an extract with a dose of 100 mg/KgBB, group 5 was given the N-Hexane fraction with a dose of 100 mg/KgBB, group 6 was given the Ethyl Acetate fraction with a dose of 100 mg/KgBB, group 7 was given the N-Butanol fraction with a dose of 100 mg/KgBB, group 8 was given the Residual Water Fraction with a dose of 100 mg/KgBB, the treatment was carried out for 2, 4, 6 days, in the SGPT test used was serum. Results: The administration of extracts and fractions to animals did not cause Subacute Toxicity effects on the livers of male white mice. Looking at the SGPT (Serum Glutamic Pyruvic Transaminase) parameters, the activity of which was still within normal conditions, namely 25-200 µ/l. Conclusions: did not show any Subacute Toxicity effects as seen from the activity of the SGPT enzyme in the blood of male white mice (Mus musculus).
Cost-Effective Analysis (AEB) of Antiretroviral (ARV) Use of TLD and TLE in Outpatient HIV Patients Kurniadi Rafindra, Meidi; Andriani, Medi; Dewi, Rasmala
Jurnal Multidisiplin Indonesia Vol. 4 No. 2 (2025): Jurnal Multidisiplin Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jmi.v4i2.2207

Abstract

Antiretroviral treatment is one of the biggest parts of the treatment for people infected with HIV. This study aims to determine the effectiveness of drugs and the cost efficiency of ARV combination drug therapy. The study used a non-experimental research design that was observational to determine the Cost Effectiveness Analysis of 2 combinations of ARVs, namely the combination of TLD (Tenofovir + Lamivudin + Dolutegraph), and the combination of TLE (Tenofovir + Lamivudin + Efavirenz). Data collection was carried out retrospectively from the medical record data of patients who started ARV treatment in the period 2021 to 2023. Total of 189 patients were actively treated as outpatients at VCT polyclinics and 64 who met the inclusion criteria were used as study subjects. The effectiveness of treatment uses the parameters of the Viral Load test results. Treatment is said to be effective if the Viral Load test result is <40 copies/mL. Based on the results of the Viral Load test, the TLD combination was more effective (75.9%) compared to the TLE combination (66.7%). Based on Cost Effective Analysis, the combination of TLD (Tenofovir + Lamivudin + Dolutegrafir) is better with an ACER value of IDR 39,871 compared to the combination of TLE (Tenofovir + Lamivudin + Efavirenz) with an ACER value of IDR 68,599.
The Relationship between the Level of Adherence to Antiretroviral Drugs (ARVs) Use to Viral Load Levels in Outpatient HIV Patients Yulyana, Zahara; Andriani, Medi; Dewi, Rasmala
Jurnal Multidisiplin Indonesia Vol. 4 No. 2 (2025): Jurnal Multidisiplin Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jmi.v4i2.2209

Abstract

Human Immunodeficiency Virus (HIV) is a disease that is contagious to humans so that it can lower the immune system and be susceptible to diseases. Drugs given to treat HIV infection and improve the quality of life of People With HIV/AIDS (ODHA) are antiretrovirals (ARVs). Adherence to taking antiretrovirals is an important factor in the success of therapy and reducing the amount of HIV virus in the body of ODHA, so that a high level of adherence has a fairly good or undetectable viral load result. The purpose of this study is to find out if there is a relationship between compliance with viral load levels. The research method was conducted with a cross sectional design, starting from May to June 2024. The data used are the results of the MMAS-8 questionnaire that has been validated and filled out directly at the Putri Ayu Health Center in Jambi City and the results of the viral voad level laboratory. Sampling with consecutive sampling. The data obtained in the analysis by bivariate analysis used the Cramer's V with a degree of significance of p-value <0.05. The results in this study were obtained by 11 (52.4%) respondents with a high level of compliance so that the results of viral load were not detected, there were 10 respondents with a moderate and low level of compliance so that 8 (38.1%) respondents had a detected viral load result and 2 respondents were not detected. There was a significant relationship with adherence to taking antiretroviral drugs to viral load levels with a result of 0.000 p-value <0.05 or 5%.
Gerakan Masyarakat Peduli Kesehatan Tanggap Penggunaan Obat dan Kosmetik yang Aman Andriani, Medi; Hafsari, Winda Galuh; Putri, Rezky Amelia; Amelda, Mustika Dwi; Almukharomah, Adella; Amelia, Faranita Nur; Oktaniasih, Putri; Oktapiani, Fenti; Kirana, Sahla Tahta; Safitri, Desti Rizkyan
Jurnal Abdimas Kesehatan (JAK) Vol. 7 No. 2 (2025): Juni
Publisher : Universitas Baiturrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36565/jak.v7i2.915

Abstract

Community Service carried out by a group of students in order to advance the welfare of the community and educate the nation's life. This activity was carried out in Mersam Village, Mersam District, Batanghari Regency. It was carried out using the method of providing learning experiences in the form of socialization and counseling that went directly to the community carried out by students and lecturers, carried out within 30 days. The results of several activities that we have carried out are in the activity of checking hypertension and blood sugar health, the results were obtained from 40 people who participated in this activity, who had blood pressure> 120/80 mmHg as many as 6 people, 120 - 129/80 - 84 mmHg as many as 9 people, 130 - 139/85 - 89 as many as 7 people, and> 140/90 mmHg as many as 18 people. And have normal blood sugar levels (>99 mg/dl) as many as 7 people, pre-diabetes (100-180 mg/dl) as many as 21 people, Diabetes (>200 mg/dl) as many as 12 people. This KKN activity has succeeded in increasing the knowledge and participation of Mersam Village residents regarding personal and environmental health, increasing local roles and resources, increasing community independence and welfare as well as knowledge for Mersam Village residents regarding the correct use of drugs and safe cosmetics.
ANALISIS GAMBARAN TERAPI DAN INTERAKSI OBAT PADA PASIEN MIXED ANXIETY AND DEPRESSIVE DISORDER DI RUMAH SAKIT ISLAM ARAFAH KOTA JAMBI TAHUN 2021-2023 Andriani, Medi; Sanuddin, Mukhlis; Umairoh, Sarah
Jurnal Farmasi (Journal of Pharmacy) Vol 14, No 1 (2025)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v14i1.331

Abstract

Mixed Anxiety and Depressive Disorder (MADD) adalah kondisi individu yang mengalami gejala kecemasan dan depresi secara bersamaan, namun tidak memenuhi semua kriteria diagnostik untuk gangguan ansietas dan gangguan depresi. Saat gejala ansietas dan depresi muncul bersamaan akan menyebabkan penurunan fungsi yang signifikan terhadap penderita. Pada tahun 2015, diperkirakan lebih dari 300 juta orang di seluruh dunia menderita depresi dan ansietas. Berdasarkan data Kementerian Kesehatan Republik Indonesia prevalensi depresi di Provinsi Jambi adalah 1,8%. Selama pandemi COVID-19 didapatkan prevalensi ansietas sebanyak 32,2%. Penelitian ini bertujuan untuk menganalisis gambaran terapi dan potensi interaksi obat pada pasien MADD di Rumah Sakit Islam Arafah Kota Jambi. Sampel penelitian merupakan pasien yang didiagnosa MADD pada tahun 2021-2023 berjumlah 153 pasien. Pengambilan data pada penelitian menggunakan metode retrospektif yaitu penelusuran data sekunder rekam medis. Hasil Penelitian menunjukan bahwa resep racikan banyak diresepkan pada tahun 2021-2023 yaitu berturut-turut sebanyak 52%, 52% dan 50%. Golongan obat yang diresepkan pada penderita MADD pada tahun 2021-2023 berupa antidepresan dan benzodiazepine. Golongan obat pada pasien yang memiliki penyakit penyerta paling banyak diresepkan adalah antipsikotik berturut-turut sebanyak 16%, 17% dan 18% dan golongan antihipertensi sebanyak 3% pada tahun 2021-2023. Obat yang paling banyak diresepkan pada tahun 2021-2023 adalah sertraline sebanyak 14%, 14%, 11% dan alprazolam sebanyak 13%,13% dan 15%. Dosis sertraline yang diresepkan yaitu 50 mg dan alprazolam 0,25 mg, 0,5 mg dan 1 mg. Frekuensi sertraline yang diresepkan yaitu 1x perhari dan 2x perhari.  Frekuensi alprazolam yang diresepkan yaitu 1x perhari dan 2x perhari. Kasus interaksi obat paling banyak yaitu pada tingkat moderat (aripiprazole-sertraline) sebanyak 7% dan 8% pada tahun 2021 dan 2022, sementara pada tahun 2023 sebanyak 9% (alprazolam-aripiprazole).
Pola Penggunaan Antibiotik pada Penyakit ISPA di Puskesmas Koto Baru Kota Sungai Penuh Periode 2022-2023 Zhafirah, Wara; Andriani, Medi; Sanuddin, Mukhlis
Jurnal Akademika Baiturrahim Jambi Vol. 14 No. 2 (2025): September
Publisher : Universitas Baiturrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36565/jab.v14i2.957

Abstract

Acute Respiratory Infections (ARI) are among the most common diseases in the community and often require the use of antibiotics for treatment. However, inappropriate use of antibiotics can lead to antibiotic resistance, which is a global health problem. This study aims to analyze the patterns of antibiotic use in ARI patients at Koto Baru Health Center, Sungai Penuh City, during the period 2022-2023. This research is a descriptive study with a retrospective approach. Data were collected from the medical records of patients diagnosed with ARI at Koto Baru Health Center during the period 2022-2023. The information collected included the type of antibiotic used, route of administration, frequency of administration, and rationality. The data were analyzed to identify patterns of antibiotic use and their compliance with existing therapeutic guidelines. The study found that, based on gender, 72% of the patients were female. Based on age, 52% of the patients were 13-33 years old and 68% were 33-53 years old. A total of 87% of the patients did not have any comorbidities. The most commonly used antibiotic was amoxicillin, with 100% appropriate route of administration. The frequency of appropriate antibiotic administration was 84% in patients aged 13-33 years and 91% in patients aged 33-53 years. The rationality of antibiotic use was recorded at 85% in patients aged 13-33 years and 90% in patients aged 33-53 years. This study shows that the use of antibiotics in ARI patients at Koto Baru Health Center generally complies with therapeutic guidelines, especially in terms of the route of administration. However, there are some discrepancies in the frequency and rationality of antibiotic use that need to be addressed. Continuous education and training for medical personnel are necessary to improve the appropriateness of antibiotic use and reduce the risk of resistance
Co-Authors Aan Putra Afdonil Khomarul Fatta Afrida, Erni Aisa Dinda Mitra Al Fadhilah, Shafira Almira Salsabila, Nandita Almukharomah, Adella Amelda, Mustika Dwi Amelia, Faranita Nur Anandita, Nada Anggelia pratiwi Anggita Septia Meriza Apria, Habibah Aprilia Wulandari Armini Hadriyati Armini Hadriyati Asnadewi, Veni Astari, Wita Athayyah Shabirah Aulia Fatihah, Anya Azhari Putri, Nabila Cupa Munti, Putri Delina Dameria Sibuea, Lasma Desi Ambar Sari Dewi Permata Sari Dewi Permata Sari Dewi, Rasmala Dewi, Rasmala Diah Suci Ramadhani Disty Aldila Wicaksono Erinda Rizki Putri Erni Afrida Fatta, Afdonil Khomarul Fitrawati Fitrawati Fitrawati Fitrawati Haerul Afdal Mubarak, Mohd Hafsari, Winda Galuh Hasanah, Rifdatul Hidayati, Atriani Ibriyanti, Silda Indri Meirista Jelly Permatasari Kirana, Sahla Tahta Kurniadi Rafindra, Meidi Lasma Dameria Sibuea Lili Andriani Lina, Ade Okta Maharani, Juliantika Manik, Feranika Martua, Aris Sahat Meriza, Anggita Septia Mohd Haerul Afdal Mubarak Muchtar, Melayusma Nada Anandita Nandita Almira Salsabila Nasril, Siska Emilia Natari, Rifani Bhakti Nike Nur Ahdiyah Nofrida Saswati nofrida saswati, nofrida Nolasari, Raiza novrianti, wulan nur NR. Umil Hasanah.R Oktaniasih, Putri Oktapiani, Fenti Oliyen Madori Ongki Aleksander Opi Zalita , Tricy Parman Permata Sari, Vira Putra, Rizki Yulion Putra, Rizky Yulion Putri Armellia, Sagita Putri, Elfiana Meirela Putri, Erinda Rizki Putri, Kiki Ananda Putri, Rezky Amelia Rahayu, Rajani Sri Raiza Nolasari Rifdatul Hasanah Rizki, Sri Puri Rizky Yulion Rosyta, Dini Galoh Safitri Nada, Lia Safitri, Desti Rizkyan Sagita Putri Armellia Sandi, Putri Lara Santi Perawati Sanuddin, Mukhlis Saputri, Ghina Nabilla Dwi Sepriani Sepriani Sepriani Sepriani, Sepriani Shabirah, Athayyah Siti Nurhaliza Sri Bintang Sahara Mahaputra Kusumanegara Sri Puri Rizki Sutrisno , Deny Syamsul Arifin Ulfa, Zakia Umairoh, Sarah Umil Hasanah.R, NR. Wita Astari WULANDARI, APRILIA Yasril, Farih Rahma Yuli Hidayati Yuliandani, Yuliandani Yulianis Yulianis Yulianis Yulianis Yulianis Yulianis Yulyana, Zahara Yuni Andriani Zhafirah, Wara