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All Journal UNEJ e-Proceeding JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Science and Technology Indonesia Panrita Abdi - Jurnal Pengabdian pada Masyarakat Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat JMM (Jurnal Masyarakat Mandiri) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Pharmaceutical Journal of Indonesia Community Development Journal Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Medical Sains : Jurnal Ilmiah Kefarmasian
Tristiana Erawati Munandar
Departemen Ilmu Kefarmasian, Fakultas Farmasi, Universitas Airlangga, Surabaya
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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PENDIDIKAN KOGNITIF DAN AFEKTIF DAGUSIBU UNTUK PENCEGAHAN RESISTENSI ANTIBIOTIK DI SMA SURABAYA Abhimata Paramanandana; Dini Retnowati; Andang Miatmoko; Dewi Isadiartuti; Sugiyartono1; Mohammad Agus Sjamsur Rijal; Dwi Setiawan; Esti Hendradi; Tutiek Purwanti; Noorma Rosita; Dewi Melani Hariyadi; Tristiana Erawati; Ardhani Dwi Lestari1; Helmy Yusuf; Retno Sari
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 1 (2019): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (620.49 KB) | DOI: 10.32734/abdimastalenta.v4i1.2395

Abstract

Antibiotics are not only used for humans, but also often used for cattle and livestock which are then been consumed by humans. This over prescribed and missed used of antibiotic is a major factor in antibiotic resistance. Antibiotic resistance is a condition where bacteria are unable to be treated with antibiotics. In fact, the use of antibiotics is the first response in curing infectious diseases (by bacteria) and preventing infectious diseases spreading. With antibiotic resistance, preventing infectious diseases by bacteria became harder. This community service activity came up with a slogan "Antibiotic Resistence Awareness Movement" was carried out in Surabaya 10 Public High Schools and Surabaya 17 Public High Schools with 60 students per school using several methods, namely: (a) giving lecture material using LCD projectors ) the implementation of poster making competitions, and (c) poster presentations that have been made that are accompanied by question and answer, and (d) evaluation activities in the form of written tests covering pre-test and post-test. Concerning the results of posters results, poster presentations and improving the results of this posttest can be concluded as a result of an increase in understanding and or knowledge of students of SMA 10 and SMA 17 Surabaya
Molecular Docking of Flavan-3-Ol Compounds from Cocoa Beans Againts Matrix Metalloproteinases (MMPs) as Anti-Photoaging Agents Cindi Dia Annisa; Tristiana Erawati; Widji Soeratri; A'liyatur Rosyidah, M.Si., Ph.D
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 3 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i32025.312-320

Abstract

Background: Premature aging of the skin is an abnormal aging process that is primarily triggered by UV exposure, which leads to increased production of matrix metalloproteinases (MMPs). These enzymes degrade skin collagen. The abundant flavan-3-ol content of cocoa beans has been demonstrated to possess antioxidant properties, thereby serving as a potential agent to impede premature aging. A molecular docking approach can facilitate the prediction of cocoa bean flavan-3-ols' capacity to impede MMP enzyme activity. Objective: This study aims to predict the interaction between cocoa bean flavan-3-ol compounds and MMP enzymes as potential photoaging inhibitors. Methods: Flavan-3-ol compounds from cocoa beans, including (-)-epicatechin, (+)-catechin, procyanidin B1, B2, and C1 were obtained from PubChem and modeled in 3D using ChemDraw 3D software. These compounds were docked into the collagenase (MMP-1), stromelysin (MMP-3), and gelatinase (MMP-9). The docking results were compared to native ligands of the proteins. AutoDock was used for docking, and the results were visualized using Biovia Discovery Studio. Results: Method validation confirmed that all proteins were suitable for docking. The docking results showed negative docking scores for all compounds, with each compound binding at least one amino acid residue similar to native ligands. Procyanidin B2 exhibited the best docking score and the smallest inhibition constant for collagenase and gelatinase 9. Conclusion: Cocoa bean flavan-3-ol compounds can inhibit collagenase, stromelysin, and gelatinase activity. Procyanidin B2 is the most effective compound among those tested. Consequently, further testing may be undertaken to generate supporting evidence for potential utilization of cocoa beans as an active compound in cosmetic formulations.
Formulation, Physical Characterization, and Stability Study of Nanoemulgel Containing Jatropha curcas Leaves Extract Aly, M. Ainun Najib; Pratama, Edo; Shobahah, Jauharotus; Munandar, Tristiana Erawati; Sukardiman
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 3 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i32025.407-413

Abstract

Background: Jatropha curcas extract has been identified as a promising herbal remedy for various skin disorders. However, its application is limited by its low water solubility and poor skin permeability. Nanotechnology-based strategies provide a way to overcome these limitations. Objective: This study aimed to develop a new drug delivery system for J. curcas extract as a topical treatment for skin conditions. Methods: J. curcas extract was obtained through maceration. The system included a Carbopol 940-based gel and a J. curcas extract (JCE 10% w/w) nanoemulsion (NE) created using a high-energy method with an ultrasonic homogenizer. The appearance, pH, viscosity, spreadability, particle size, polydispersity index, and zeta potential of the nanoemulgel were assessed to verify its physical properties. Results: The optimal formulation produced a dark green nanoemulgel with a distinctive leafy smell and a semi-solid texture. Physical characterization of the JCE-NE-gel included a pH of 6.3, particle size of 142.67 nm, polydispersity index of 0.248, zeta potential of -23.23 mV, viscosity of 87.881 cP, and spreadability of 6.13 cm. Stability testing showed no significant differences after accelerated stability testing and thermal cycling. Conclusion: The study demonstrated that J. curcas extract (JCE-NE-gel) was successfully incorporated into a nanoemulgel formulation (F4), showing excellent physical properties and stability.
Edukasi kesehatan melalui webinar tentang swamedikasi obat modern dan tradisional untuk menjamin efektivitas pengobatan Wiwied Ekasari; Retno Widyowati; Andang Miatmoko; Achmad Syahrani; Tristiana Erawati Munandar; Aty Widyawaruyanti; Suciati Suciati
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 2 (2024): June
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i2.22834

Abstract

AbstrakSwamedikasi merupakan salah satu cara masyarakat untuk mengatasi keluhan penyakit yang tergolong ringan. Tren ini semakin meningkat selama pandemi COVID-19 berlangsung seiring dengan adanya berbagai aturan pembatasan yang membuat hampir seluruh lapisan masyarakat membatasi kegiatan di luar rumah. Sangat penting untuk masyarakat memiliki pengetahuan yang memadai, baik tentang obat modern dan tradisional, untuk menjamin efektivitas obat sehingga kesembuhan atau perbaikan kesehatan yang diharapkan dapat tercapai. Berdasar hal tersebut diselenggarakan  pengabdian kepada masyarakat dalam bentuk penyuluhan guna meningkatkan pemahaman masyarakat mengenai swamedikasi obat modern dan tradisional. Penyuluhan berbasis online dengan metode ceramah dan diskusi melalui webinar melibatkan 305 peserta dari berbagai daerah di Indonesia. Penilaian pemahaman masyarakat melalui pre-test sebelum dan post-test setelah materi webinar diberikan. Hasil analisis menunjukkan bahwa tingkat pengetahuan masyarakat umum meningkat signifikan (p < 0,05) yang ditandai dengan nilai rata-rata pre-test sebesar 54,47 dan nilai rata-rata post-test sebesar 74,89. Sama halnya dengan tingkat pengetahuan tenaga kefarmasian juga meningkat signifikan (p < 0,05) dengan nilai rata-rata pre-test sebesar 75,15 dan nilai rata-rata post-test sebesar 86,59. Berdasar hasil tersebut dapat disimpulkan bahwa pengabdian kepada masyarakat ini berpengaruh terhadap tingkat pengetahuan masyarakat umum dan tenaga kefarmasian mengenai obat modern dan tradisional sehingga dapat menjamin efektivitas pengobatan dan didapatkan mutu kesehatan yang maksimal. Kata kunci: COVID-19; kesehatan masyarakat; obat modern; obat tradisional. AbstractSelf-medication is one way for the community to deal with complaints of ailments that are classified as mild. This trend has increased during the COVID-19 pandemic along with various restrictions that have made almost all levels of society restrict activities outside the home. It is very important for the community to have adequate knowledge, both about modern and traditional medicine, to ensure the effectiveness of the drug so that the expected recovery or health improvement can be achieved. Based on this main problem, the author provides community service in the form of counseling to increase public understanding regarding modern and traditional drug self-medication. Online-based counseling using lecture and discussion methods via webinars involved 305 participants from various regions in Indonesia. Assessment of public understanding through pre-test before and post-test after the webinar material was given. The results of the analysis show that the level of knowledge of the general public has increased significantly (p < 0.05) as indicated by the average pre-test score of 54.47 and the average post-test score of 74.89. Likewise, the level of knowledge of pharmaceutical staff also increased significantly (p < 0.05) with an average pre-test score of 75.15 and an average post-test score of 86.59. Based on these results, it can be concluded that this community service influences the level of knowledge of the general public and pharmaceutical staff regarding modern and traditional medicine so that it can guarantee the effectiveness of treatment and obtain maximum health quality. Keywords: COVID-19; public health; modern medicine; traditional medicine.
Drug and cosmetic safety training for cadres of family welfare program Tristiana Erawati; Dewi Melani Hariyadi; Noorma Rosita; Widji Soeratri; Tutiek Purwanti; Hadi Poerwono; Marcellino Rudyanto; Helmy Yusuf; Djoko Agus Purwanto; I Nyoman Wijaya
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol. 9 No. 2 (2024): May 2024
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v9i2.11161

Abstract

In order to increase public understanding and awareness regarding the safety use of drugs and cosmetics, the Community Service Team of the Faculty of Pharmacy, Airlangga University has held community service in Jonggrangan Village, Klaten, Central Java. The community service was carried out on July 31, 2023, with approximately 60 family welfare programs or PKK cadres and health cadres participating through training, presentations, and discussions. The activity began with a pre-test, continued with training, a presentation of the material by three experts, and a discussion, then ended with giving a post-test to the participants. The results of the pre and post-test analysis showed that participants' understanding increased. The results of the analysis of the answers to the 15 questions given showed that the increase in participants' understanding ranged from  2.13-46.02 percent. The impact of these activities on society. The increase in participants' understanding of each topic is not the same depending on the initial understanding. However, the problem is that the level of public understanding after receiving training is still below 50 percent namely on topics about the stages of using cosmetic products and about drug classification. So it is necessary to deepen the material using other strategies (appropriate methods and media).
Co-Authors A'liyatur Rosyidah, M.Si., Ph.D Aly, M. Ainun Najib Andang Miatmoko Ardhani Dwi Lestari1 Aty Widyawaruyanti Bambang Tri Purwanto Cahyono, Definta Anisa Tamara Cindi Dia Annisa Cita Rosita Sigit Prakoeswa Dewi Isadiartuti Dewi Melani Hariyadi Dini Retnowati Diyah, Nuzul Wahyuning Djoko Agus Purwanto Dwi Setiawan Esti Hendradi Esti Rahayuningtyas Eva Syariefah Rachman Fedik Abdul Rantam Fransisca Dita Mayangsari Hadi Poerwono Hamdan, Siti Hartini Hanafi Tanojo Handayani, Rosita Harjono Suko Herra Studiawan I Gusti Ayu Adhi Aryapatni I Nyoman Wijaya Idha Kusumawati Marcellino Rudyanto Maria Lucia Ardhani Dwi Lestari Mohammad Agus Sjamsur Rijal Nisa Qurrota Ayun Noorma Rosita Paramanandana, Abhimata Pradita Fiqlyanur Isna Primadana Pratama, Edo Ressa Marisa Retno Sari Retno Sari Retno Widyowati Ria Hanistya Ria Puspita Rina Mutya Suzliana Safiul Fitria, Nur Indah Sari Retno Sari, Trisiyana Sholika Shobahah, Jauharotus Suciati Suciati Sudjarwo Sudjarwo Sugiyartono, Sugiyartono Sugiyartono1 Sukardiman Suko Hardjono Syahrani, Achmad Tekla Kalalo Tutiek Purwanti Virnanda Syafira Hartatiningrum Widji Soeratri Widji Soeratri Widji Soeratri Wiwied Ekasari Yusuf, Helmy Yusuf, Helmy Yuwono Mochamad Zhihrotulwida, Dzakiya