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Immunomodulatory Activity of Xestospongia sp. Ethanolic Extract Towards Interferon-gamma (IFN- γ) and Tumor Necrosis Factor-alpha (TNF-α) Levels in Wistar Male Rats Fristiohady, Adryan; Jumadil; Wahyuni; Malaka, Muh. Hajrul; Harnita, Wa Ode; Sadarun, Baru; Yodha, Agung Wibawa Mahatva; Saripuddin; Purnama, La Ode Muhammad Julian; Sahidin, Idin
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2020.v6.i2.15231

Abstract

Xestospongia sp. is one of marine sponge belongs to demosponges class that mainly found in Southeast Sulawesi and the secondary metabolites contained in Xestospongia sp. suspected to have immunomodulatory activity. A previous study exhibited the immunomodulatory of Xestospongia sp. ethanolic extract (XEE) at dose of 300 and 400 mg/Kg BW by affecting the phagocytic activity of macrophages. Thus, this study aims to investigate the effect of XEE towards interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) at dose of 300 and 400 mg/Kg BW. Wistar male rats are divided into 4 groups (n=6) randomly and treated for 7 days orally each as follow: group I (XEE dose of 300 mg/KgBW); group II (XEE dose of 400 mg/KgBW); group III (0.5% NaCMC); and group IV (commercial phylantii extract). On day 8, animals were infected with Staphylococcus aureus and left for 1 hour. Animals were sacrificed and the blood was drawn by cardiac puncture (3 mL), followed by analyzed under ELISA Kit for IFN-γ and TNF-α. Collected data were analyzed statistically using SPSS®. The IFN-γ levels obtained were 350.113; 392.970; 118.416; and 61.958 ρg/mL, respectively and the TNF-α were 2808; 1308; 778; and 845.5 ρg/mL, respectively. According to results obtained, both doses of XEE are affecting the IFN-γ and TNF-α levels (p<0.05) compared to group III as negative control, and group IV as positive control. As conclusion, XEE of both doses is increasing IFN-γ and TNF-α levels of animals that respond to phagocytic activity
Patterns of Qur'anic Study Approaches for Preventing Radicalism in Singapore Muchtar, M. Ilham; Amin, Saifuddin; Jumadil
QOF Vol. 8 No. 1 (2024)
Publisher : Institut Agama Islam Negeri (IAIN) Keiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30762/qof.v8i1.2184

Abstract

This study explores the paradigms and approaches employed in Quranic studies to mitigate radicalism in Singapore. A qualitative descriptive methodology was utilised to examine the patterns of Quranic study. The primary and secondary data sources comprised the Muslim community in the country, alongside relevant literature including books, journals, and research reports. Data collection methods included interviews, documentation, and observation, with subsequent analysis conducted using qualitative data analysis techniques. The findings reveal that while the Muslim community generally enjoys the freedom of religious practice and access to Islamic educational institutions and organisations, the government has instituted regulations to ensure that Quranic study promotes moderate thought, openness, and interreligious harmony. Although the city provides a conducive environment for Quranic studies, measures are in place to maintain social harmony and prevent potential radicalisation. The Majlis Ugama Islam Singapura (MUIS) mandates requirements for preachers, including obtaining permits, demonstrating speaker competency, ensuring appropriate content, providing security assurance, and securing location permits. MUIS employs three main approaches in Quranic study: 1) categorising preachers based on their knowledge, experience, and skills; 2) using interpretive methods such as thematic, linguistic analysis, historical, and comparative approaches, which are regularly evaluated; and 3) monitoring the content of the material through reporting mechanisms and documentation from the start to the end of activities. The study concludes that the approach to Quranic study in the country plays a significant role in shaping understanding and the application of Islamic teachings, underpinned by the values of moderation and religious tolerance.
Model Ketahanan Pangan Berbasis Peternakan Lokal: Solusi Ketersediaan Daging Tanpa Impor Jumadil
ARMADA : Jurnal Penelitian Multidisiplin Vol. 3 No. 4 (2025): ARMADA : Jurnal Penelitian Multidisplin, April 2025
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/armada.v3i4.1614

Abstract

Ketahanan pangan merupakan isu strategis yang sangat penting bagi kedaulatan suatu negara. Salah satu tantangan utama dalam mewujudkan ketahanan pangan di Indonesia adalah ketergantungan pada impor daging untuk memenuhi kebutuhan konsumsi nasional. Penelitian ini bertujuan untuk merumuskan model ketahanan pangan berbasis peternakan lokal sebagai solusi alternatif dalam menjamin ketersediaan daging secara berkelanjutan tanpa bergantung pada impor. Pendekatan yang digunakan dalam penelitian ini adalah deskriptif-kualitatif dengan metode studi literatur dan analisis data sekunder dari berbagai sumber terpercaya. Hasil penelitian menunjukkan bahwa penguatan peternakan lokal, terutama skala kecil dan menengah, memiliki potensi besar dalam menopang ketersediaan daging nasional. Faktor-faktor kunci yang mendukung keberhasilan model ini meliputi: penguatan kelembagaan peternak, peningkatan akses pembiayaan dan teknologi, dukungan kebijakan pemerintah, serta pengembangan rantai pasok dan pasar yang efisien. Model ketahanan pangan ini juga mengintegrasikan aspek keberlanjutan lingkungan, sosial, dan ekonomi. Dengan optimalisasi potensi sumber daya lokal, pengembangan peternakan berbasis komunitas, dan pemanfaatan teknologi tepat guna, Indonesia dapat meningkatkan produksi daging domestik secara signifikan. Penelitian ini merekomendasikan pembentukan sinergi antara pemerintah, peternak, swasta, dan lembaga riset untuk merealisasikan model peternakan lokal sebagai fondasi ketahanan pangan nasional. Implikasi dari penerapan model ini adalah berkurangnya ketergantungan terhadap impor daging, meningkatnya kesejahteraan peternak lokal, dan terwujudnya kemandirian pangan nasional.
An Investigation of the Student's Reading Comprehension Difficulties at Ma Al - Muslimun NWDI Tegal Meninting, Batulayar, Lombok Barat Jumadil; Sukarni, Sri; Aprionoto
Arus Jurnal Sosial dan Humaniora Vol 4 No 3: Desember (2024)
Publisher : Arden Jaya Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57250/ajsh.v4i3.897

Abstract

The purpose of this study was to determine the most difficult aspects of reading comprehension, especially in descriptive texts experienced by class X students of MA AL Muslimun NWDI Tegal and the factors that cause these difficulties. This study uses a qualitative method, where tests and interviews are used as instruments in data collection. The subjects of this study were class X students of MA AL Muslimun NWDI Tegal Sigi in the 2024/2025 academic year. The test was given to 10 students and consisted of 15 questions divided into five types of questions, namely main ideas, finding references, understanding vocabulary, making conclusions, and detailed information. Then, the researcher interviewed 5 students by giving them 10 questions. The test results showed that the most difficult aspects faced by class X students of MA AL Muslimun NWDI were understanding long sentences, understanding main ideas, understanding grammar, in concluding the contents of vocabulary text readings. While the findings of the interviews, however, indicated that both internal and external variables contributed to students' challenges in comprehending texts. Lack of reading methods, a small vocabulary, and little student motivation are internal issues. The environment of the learner is an example of an external component.
TINDAK TUTUR ILOKUSI, FUNGSI, DAN IMPLIKATURNYA DALAM WACANA IKLAN RESTAURANT DI SENGGIGI Jupri; Jumadil
Jurnal Cahaya Mandalika ISSN 2721-4796 (online) Vol. 4 No. 3 (2023)
Publisher : Institut Penelitian Dan Pengambangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jcm.v4i3.1701

Abstract

Wacana digunakan sebagai media penyampaian pesan, termasuk Wacana Iklan Restoran di daerah Senggigi. Maksud yang dituturkan oleh penutur dapat disampaikan secara tersurat maupun tersirat. Secara pragmatis fungsi tuturan merupakan fungsi yang diacu oleh maksud tuturan di dalam pemakaiannya untuk berkomunikasi. Masalah yang diteliti adalah; jenis tindak tutur ilokusi apa yang terdapat dalam wacana iklan Restaurant Senggigi; fungsi pragmatis tindak tutur ilokusi apa yang terdapat dalam wacana iklan Restaurant Senggigi, dan; apa saja implikatur yang terdapat dalam wacana iklan Restaurant Senggigi. Pendekatan yang digunakan adalah pendekatan teoretis dan metodologis. Pendekatan teoretis yang digunakan adalah pendekatan pragmatik, sedangkan pendekatan metodologis yang digunakan adalah pendekatan kualitatif dan deskriptif. Data yang digunakan adalah penggalan wacana iklan, pengumpulan data metode simak dan teknik catat. Analisis data dengan metode heuristik. Sumber datanya adalah wacana iklan berupa baliho, spanduk, dan poster di Restaurant di daerah Senggigi selama Bulan Desember 2022 sampai Maret 2023. Dari hasil analisis data dalam penelitian ini ditemukan ada tiga tindak tutur, yaitu (1) jenis tindak tutur ilokusi (1) tindak tutur ilokusi asertif, (2) tindak tutur ilokusi ekpresif, (3) tindak tutur ilokusi komisif, (4) tindak tutur ilokusi direktif, dan (5) tindak tutur ilokusi isbati. Fungsi pragmatis tindak tutur ilokusi yang ditemukan (1) tindak tutur asertif menyatakan ada delapan dan fungsi mengklaim ada dua, (2) tindak tutur ekpresif fungsi menyanjung ada enam, (3) tindak tutur komisif fungsi menawarkan ada tiga dan fungsi menjanjikan ada satu, (4) tindak tutur direktif fungsi merekomendasi ada sepuluh, fungsi menyarankan ada lima, dan fungsi mengajak ada empat, dan (5) tindak tutur isbati fungsi memberi nama ada tiga. Implikatur ditemukan implikatur yang memberi pernyataan dan ajakan. Berdasarkan temuan tersebut disimpulkan bahwa terdapat tindak tutur ilokusi beserta fungsi pragmatisnya juga implikatur. Ini berarti Wacana Iklan Restoran Senggigi sebagai salah satu bentuk wacana iklan yang menunjukkan adanya interaksi. Adapun saran yang diberikan (1) calon peneliti khusunya bidang bahasa, hendaknya melakukan penelitian secara menyeluruh serta peneliti pada khususnya guna pengembangan kebahasan lebih lanjut, sehingga maksud dan tujuan dalam bertutur yang disampaikan dapat dimengerti oleh banyak pihak, (2) pembaca, hasil penelitian ini dapat dijadikan sebagai bahan acuan atau rujukan sekaligus penambah wawasan tentang fenomena-fenomena bahasa yang terjadi di masyarakat, dan (3) pembuat wacana iklan persuasif hendaknya menggunakan tindak tutur direktif merekomendasi, untuk merekomendasikan tempat, rasa, harga, dan menu yang disajikan berbeda dengan yang lain.
Pengembangan Ensiklopedia Jamur Makroskopis Sebagai Media Pembelajaran Mardin, Herinda; H. Husain, Ilyas; D. Mamu, Hartono; Jumadil
Jurnal Biogenerasi Vol. 9 No. 1 (2024): Terbit volume 9 nomor 1 tahun 2024
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v9i1.3171

Abstract

The aim of this research is to test the feasibility of developing a macroscopic mushroom encyclopedia as a learning medium. This research is Research and Development (R&D) research. The research procedure adapted the ADDIE development model. The adaptation of the ADDIE model in this research was carried out at the encyclopedia validation stage. The encyclopedia validation test was carried out by two expert validators, namely a material expert validator and a media expert validator. Next, validators are asked to provide a general assessment and suggestions regarding the encyclopedia that has been developed, whether the encyclopedia is valid or invalid. Validation of the macroscopic fungal encyclopedia is in the very feasible category with a percentage of 92% by media expert validators and a percentage of 91% by material expert validators. The results of the validity test show the category is very feasible, which means that the resulting encyclopedia media does not need to be revised and is suitable for testing.
Design of Seaweed Liquid Waste Processing Installation in the Alkali Treatment Process as Recycled Water Based on Physics and Chemistry Akrim, Djusdil; Suparno; Fikruddin, Muh; Jumadil; Anggraini, Nani; Syaiful, Andi Zulfikar; Hamsina; Ridwan
Jurnal Penelitian Pendidikan IPA Vol 10 No 6 (2024): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i6.6312

Abstract

World seaweed production in 2020 published by the Food and Agriculture Organization of the United Nations (FAO), Indonesia was ranked second as the largest seaweed producer with production of 11.8 million tons. The aim of this research is: To analyze the characteristics of seaweed liquid waste at PT. XYZ. To design a seaweed liquid waste processing process at PT. XYZ based on physics-chemistry as recycled water. Methods include analysis and experiments. This method is used to analyze the characteristics of liquid waste and determine the design of the seaweed liquid waste processing process at PT. XYZ. Research results: The characteristics of the seaweed liquid waste produced do not meet the quality standards in Kep.08/Men. LH/2009 concerning Industrial Waste. A physic-chemical based liquid waste processing process with neutralization, filtering and aeration can be used as recycled water in the alkali treatment process.
Study of Urban Growth Center Development Factors and Simulation The Mamminasata Urban Area Rasyidi, Emil Salim; Jumadil; Syafri; Rahman, Rahmawati; Rusneni; Hamsinah; Jibran, Muh. Khalil
Jurnal Penelitian Pendidikan IPA Vol 10 No 4 (2024): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i4.6380

Abstract

Urban growth starts from a center and affects the surrounding areas, this is due to the emergence of additional centers that will each function as growth poles, to study the dynamics related to urban growth center information, several data and extraction and analysis methods are needed. This study examines several methods of extracting information on urban growth centers from Landsat 8 OLI/TIRS in 2013 and 2023 by utilizing the spectral resolution of Landsat imagery in the Mamminasata area, and integrating spatial modeling to simulate the growth centers of the Mamminasata area in the next 10 years (2043). The results of this research classification method show an accuracy rate of 71.48%. The results of the determinant factor test show that the most influential factors are the distance from the center of shops, slope, then the distance from the university, and the distance from the main road in 2013-2023 Mamminasata Urban Area. The results of this variable drive test are then used in spatial simulations using the markov chain simulation method in the LCM module and show an increase in the area of the growth center in the Mamminasata region, for the entire scope of the Mamminasata region, the Makassar City area shows the highest intensity of regional growth centers and becomes the center of growth in the Mamminasata urban area. The planning concept applied to the results of this study is based on resources, geographic location, and factors affecting the growth center.