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All Journal PREPOTIF : Jurnal Kesehatan Masyarakat Green Medical Journal INDONESIAN JOURNAL OF HEALTH Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Fakumi Medical Journal
Andi Sitti Fahirah Arsal
Departemen Farmakologi Fakultas Kedokteran Universitas Muslim Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : Green Medical Journal

 1 
EFEKTIVITAS EKSTRAK DAUN KELOR ( MORINGA OLEIFERA) TERHADAP PENURUNAN KADAR KOLESTEROL TOTAL PADA TIKUS PUTIH ( RATTUS NOVERGICUS) Sri Wahyu; Andi Sitti Fahirah Arsal; Indah Chintya Maharani
Green Medical Journal Vol 1 No 1 (2019): Green Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (632.676 KB) | DOI: 10.33096/gmj.v1i1.24

Abstract

  Pendahuluan: Prevalensi hiperkolesterolemia di Indonesia diperkirakan terus meningkat. Salah satu obat tradisional yang digunakan untuk menurunkan kadar kolesterol darah adalah daun kelor (Moringa oleifera Lam). Penurunan kadar kolesterol setelah pemberian  ekstrak daun kelor ini disebabkan oleh kandungan zat aktif dalam daun kelor seperti flavanoid, tanin saponin dan ?-sitosterol. Tujuan: Untuk mengetahui efektivitas pemberian ekstrak daun kelor terhadap penurunan kadar kolestrol total. Metode: Penelitian ini adalah penelitian analitik dengan menggunakan pre experimental designs dengan metode pendekatan one group pre-test post-test Dengan membandingkan kelompok perlakuan dan kelompok kontrol. Hasil: uji T berpasangan menunjukkan bahwa pada kelompok perlakuan menggunakan ekstrak daun kelor diperoleh sebelum intervensi rerata kadar kolesterol sebesar 307.40 mg/dl dan setelah interval sebesar 209.00 mg/dl. Hasil uji statistik diperoleh nilai p (0.00041) <0.05 yang berarti ada perbedaan rerata kadar kolesterol antara sebelum dan sesudah perlakuan. Begitu pula pada kelompok menggunakan obat simvastatin diperoleh sebelum intervensi rerata kadar kolesterol sebesar 271.20 mg/dl dan setelah interval sebesar 127.40 mg/dl. Hasil uji statistik diperoleh nilai p (0.009) <0.05 yang berarti ada perbedaan rerata kadar kolesterol antara sebelum dan sesudah perlakuan. Kesimpulan: Didapatkan tidak ada perbedaan yang signifikan antara pemberian ekstrak daun kelor dan pemberian obat simvastatin dalam menurunkan kadar kolesterol total darah.
Antibacterial Potency of Black Garlic Extract from Allium sativum on Escherichia coli Harun, Muhammad Alief; Buraena, Sultan; Wello, Eny Arlini; Idrus, Hasta Handayani; Arsal, Andi Sitti Fahirah
Green Medical Journal Vol 3 No 3 December (2021): Green Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/gmj.v3i3.90

Abstract

Background: Diarrhea is still one of the global issues especially in developing countries. Diarrhea can be caused by either an infectious agent or a non-infectious agent. Escherichia coli is one of the infectious agents that is responsible for causing diarrhea. Garlic (Allium sativum) is a plant that has a good antibacterial activity potential because of its organosulfur and phenolic compound. Black garlic is the product of spontaneous fermentation of garlic that has improved its bioactive compounds. Content: Antibacterial potency of black garlic extract on Escherichia coli is shown on the resistance zone that formed where the lowest zone diameter is 9,67 mm while the highest zone is 24 mm. The fermentation of black garlic happened at the temperature of 70-80°C with 75-80% for 28-40 days. Conclusion: Black garlic is shown to exhibit antibacterial activity against bacteria such as Escherichia coli. This fermented product has the potential to be a therapeutic agent for diseases caused by Escherichia coli.
Co-Authors Achmad Imron Ainun Jariah Fahay Aldi Pratama Muktar Amalia Azza Ghassani Amrizal Muchtar Andi Dhedie Prasatia Sam Armanto Makmun Aryanti bamahry Asrini Safitri Buraena, Sultan Darma, Sidrah Darussalam, Andi Husni Esa Faisal Sommeng Fanny Iskandar Fattah, Nurfachanti Febie Irsandi Fendy Dwimartyono Fiscarina Gau, Anugrah Wija Harun, Muhammad Alief Hermiaty Hermiaty Nasruddin Hermiaty Nasruddin Indah Chintya Maharani Indah Lestari Daeng Kanang Irwan, Andi Alamanda Jaya, Rika Dwi Jihan Raihanah Arkam Lisa Yunianti Lisa Yuniarti Lisa Yuniati Lisa Yuniati Muhammad Dali Amiruddin Novia D Kaprawi Nur Khairunnisa Nurelly N Waspodo Nurhikmawati Rachmat Faisal Syamsu Rachmat Faisal Syamsu Rasfayanah Selin Iriana Pasombak Sodiqah, Yani Sri Irmandha Sri Julyani Sri Wahyu Syamsu Rijal Ulfa Namirah Wello, Eny Arlini Wisudawan Wulandari, Mustika Yani Sodiqah Zulfiyah Surdam