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All Journal Dinasti International Journal of Education Management and Social Science Jurnal PORKES Jurnal Buana Farma Jurnal Pengabdian kepada Masyarakat Bina Darma Jurnal Agricultural Biosystem Engineering Arfak Chem: Chemistry Education Journal Jurnal Pengabdian Masyarakat Bangsa Journal of Pharmaceutical and Sciences. Indonesian Journal of Community Development Journal in Teaching and Education Area Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Amelia, Ayu
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EVALUASI KIMIA FISIKA DAN UJI STABILITAS SEDIAAN COLD CREAM YANG MENGANDUNG EKSTRAK ETANOL DAUN CIPLUKAN (Physalis angulata L.) DENGAN 3 JENIS MINYAK Olive, Caprylic Dan Parafin Habibie Deswilyaz Ghiffari; Delladari Mayefis; Amelia, Ayu; Gina Fernanda
Jurnal Ilmiah Manuntung Vol 11 No 1 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v11i1.917

Abstract

Physalis angulata L. (ciplukan) is an annual plant with potential medicinal properties, including pain relief. This study aims to formulate a cold cream containing ciplukan leaf extract and evaluate its physical stability. The leaf extract was obtained by maceration using 96% ethanol and concentrated using a rotary evaporator. Cold cream formulations were prepared with extract concentrations of 0%, 5%, and 10%, utilizing three types of oils (olive, caprylic, and paraffin). Evaluations included organoleptic properties, pH, homogeneity, adhesion, spreadability, viscosity, cream type, and stability, analyzed using One-Way ANOVA. Results showed that all formulations exhibited good physical properties and were classified as oil-in-water (O/W) type creams. pH values ranged from 4 to 6, adhesion times from 1.19 to 4.94 seconds, and spreadability from 4.52 to 5.16 cm, with no significant differences among extract concentrations or oil types (p > 0.05). Increasing the extract concentration from 5% to 10% resulted in a slight decrease in pH, which remained within the safe range, maintained homogeneity, slightly reduced spreadability, and improved physical stability, especially at 10%. The formulation containing 10% ciplukan leaf extract showed the best stability and was well accepted as a cold cream preparation.
Hubungan Status Gizi dan Kekambuhan Tuberkulosis di Balai Besar Kesehatan Paru Masyarakat Surakarta Febriyanti , Eka; Amelia, Ayu; Meilanda , Rastria; Syahputra , Ghalib Syukrillah
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.792

Abstract

Malnutrition can weaken the immune system, thereby increasing the risk of Mycobacterium tuberculosis infection. The aim of this study was to determine the risk of tuberculosis (TB) recurrence associated with the nutritional status of TB patients. This study was conducted at the Surakarta Center for Lung Health in 2017 using a case-control design. The study included 15 individuals in the control group (patients who had been cured of TB) and 15 individuals in the case group (patients who experienced TB recurrence). Inclusion criteria for this study were TB patients aged 18-65 years, both male and female, who had completed the full course of TB treatment, and who had complete data on nutritional status measured through Body Mass Index (BMI) and documented dietary intake in medical records. Patients with metabolic disorders or chronic diseases other than TB that could influence nutritional status were excluded. Data were collected from medical records and analyzed using SPSS version 25. The results showed that patients with poor nutritional status (below the normal BMI) had a significantly higher risk of TB recurrence (p = 0.028). Another finding indicated that patients who had a habit of consuming alcohol also had a higher likelihood of TB recurrence (p = 0.001). The conclusion of this study is that poor nutritional status plays a role in the occurrence of recurrent tuberculosis.
Pengujian aktivitas antimikroba ekstrak daun kersen (Mutingia calabura L.) menggunakan pelarut nades (Natural Deep Eutectic Solvents) dengan metode disc diffusion Marliza, Hesti; Utami, Rury Trisa; Amelia, Ayu; Pratiwi, Reri
Arfak Chem: Chemistry Education Journal Vol. 8 No. 1 (2025): Arfak Chem
Publisher : Universitas Papua, Manokwari, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30862/accej.v8i1.889

Abstract

Antibiotic resistance is one of the significant global health challenges, prompting the search for new antimicrobial compounds from natural sources. One promising plant is cherry leaves (Muntingia calabura L.), which are known to contain flavonoids and other bioactive compounds with antibacterial potential. This study evaluated the antimicrobial activity of cherry leaf extract obtained through Ultrasound-Assisted Extraction (UAE) using Natural Deep Eutectic Solvents (NADES) as extraction solvents. Two types of NADES were used: a mixture of choline chloride: citric acid (1:2) and choline chloride: glycerol (1:2), which offer advantages such as low toxicity, high stability, non-volatility, and environmental friendliness compared to conventional organic solvents. Antimicrobial activity was assessed using the disc diffusion method against Escherichia coli and Staphylococcus aureus. The results showed that the extract using choline chloride: citric acid as solvent produced inhibition zones of 22.5 mm against E. coli and 16.05 mm against S. aureus. In contrast, the extract using choline chloride glycerol exhibited low activity against E. coli (3.41 mm) and was inactive against S. aureus. These findings indicate that combining UAE and citric acid-based NADES is an effective and sustainable approach for extracting bioactive compounds to develop natural antibacterial agents.
Pembuatan Jamu Sebagai Obat Tradisional Bersama Warga Pulau Panjang Kota Batam Ghiffari, Habibie Deswilyaz; Budiasih, Sri; Julianto, Tommy; Hainil, Sri; Gusmali, Desy Maniarti; Amelia, Ayu
Jurnal Pengabdian Masyarakat Bangsa Vol. 3 No. 5 (2025): Juli
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v3i5.2674

Abstract

Indonesia memiliki sekitar 7.000 spesies tumbuhan obat, namun pemanfaatannya belum optimal. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan warga Pulau Panjang, khususnya para ibu, mengenai obat tradisional dan cara pembuatan jamu kunyit asam sebagai alternatif pengobatan kolesterol. Kegiatan dilaksanakan pada 15 Agustus 2024 di SD Negeri 005 Galang dengan metode ceramah, demonstrasi, diskusi, dan sesi tanya jawab. Sebelum kegiatan, dilakukan survei awal untuk mengetahui tingkat pemahaman masyarakat. Hasilnya menunjukkan bahwa masyarakat masih memiliki pemahaman yang rendah terhadap obat tradisional. Sebanyak 25 peserta hadir dan menunjukkan antusiasme tinggi, terlihat dari keaktifan dalam sesi diskusi dan keinginan untuk mencoba membuat jamu sendiri. Demonstrasi dilakukan langsung oleh mahasiswa dari Institut Kesehatan Mitra Bunda Batam dengan dukungan kader setempat. Setelah kegiatan, peserta menunjukkan peningkatan pemahaman terhadap manfaat obat tradisional, khususnya kunyit sebagai penurun kolesterol. Produk jamu yang telah dibuat dibagikan kepada peserta, serta diberikan doorprize sebagai bentuk apresiasi. Kesimpulannya, kegiatan ini berjalan dengan lancar dan efektif dalam memberikan edukasi serta meningkatkan minat masyarakat terhadap penggunaan obat tradisional.
UJI ANTIBAKTERI EKSTRAK BATANG GAHARU (Aquilaria malaccensis) BERBASIS KOLIN KLORIDA:ASAM SITRAT TERHADAP Bacillus cereus dan Shigella dysenteriae Hasan, Nahrul; Marlina, Sri; Amelia, Ayu; Syahputra, Ghalib Syukrillah; Sari, Diani Mega
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1396

Abstract

Infections caused by Bacillus cereus and Shigella dysenteriae are serious health problems as they can lead to gastrointestinal disorders and contribute to the emergence of antibiotic resistance. One potential strategy to overcome this challenge is the discovery of new antibacterial agents derived from natural sources, such as agarwood (Aquilaria malaccensis). This study aimed to evaluate the antibacterial activity of gaharu stem extract using a Natural Deep Eutectic Solvent (NADES) composed of choline chloride and citric acid through the Ultrasound Assisted Extraction (UAE) method. The antibacterial assay was performed using the disc diffusion method with various NADES ratios (1:1, 2:1, 1:2, 1:3, 1:4, and 4:1 g/g), with chloramphenicol as the positive control and 10% DMSO as the negative control. The results indicated that the NADES extract with a 1:4 g/g ratio produced the largest inhibition zones against Bacillus cereus and Shigella dysenteriae. Moreover, the Minimum Inhibitory Concentration (MIC) test showed that the 1:4 NADES extract effectively inhibited bacterial growth at a concentration of 30%. These findings suggest that gaharu stem extract prepared with NADES is a promising, eco-friendly, and potent antibacterial agent.
Co-Authors Adha, Sakinah Nurlaela Ahdiah, Danies Laelatul Delladari Mayefis Fadillah, Ainun Fahrudin Fahrudin Febriyanti , Eka Garniwa, Nanang GHALIB SYUKRILLAH SYAHPUTRA, GHALIB SYUKRILLAH Ghiffari, Habibie Deswilyaz Gina Fernanda Gusmali, Desy Maniarti Gustiawati, Resty Habibie Deswilyaz Ghiffari Hasan, Nahrul Hesti Marliza Ida Ayu Putu Sri Widnyani Julianto, Tommy Kamalia, Annisa Kiska, Nurul Delima Leni Marlina Maulida, Nova Masripah Mayefis, Delladari Meilanda , Rastria Meilanda, Rastria Muhammad Amin N, Yennizar Novi Susanti Pratiwi, Reri Puspita, Asih Purwandari Wahyoe Rachmayanti, Aprilya Sri Ridwan, Ridwan Rushd, Ibnu Ruslan Abdul Gani Sammulia, Suci Fitriani Sandi Asmara Sari, Diani Mega Seandi Taroreh, Bangkit Sidiq, Abdullatif Simarni Siska, Dedi Siska, Dedy Sri Budiasih, Sri Sri Hainil, Sri Sri Marlina, Sri SUDARYANTO SUDARYANTO Suhaera, Suhaera Syahputra , Ghalib Syukrillah Syukrillah, Ghalib Utami, Rury Trisa Yunaspi, Rakhmi Febrina