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All Journal Health Science Journal of Indonesia PUJANGGA: Jurnal Bahasa dan Sastra Jurnal Masharif al-Syariah: Jurnal Ekonomi dan Perbankan Syariah Jurnal Ilmiah AL-Jauhari Jurnal Studi Islam dan Interdisipliner Eksakta : Berkala Ilmiah Bidang MIPA Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Akrab Juara : Jurnal Ilmu-ilmu Sosial Indian Journal of Forensic Medicine & Toxicology JKMM Dimensi Matematika : Jurnal Pendidikan dan Pembelajaran Matematika Jurnal Rekayasa Sipil (e-journal) YASIN: Jurnal Pendidikan dan Sosial Budaya Jurnal Pengabdian Masyarakat Waradin Jurnal Pengabdian Masyarakat Indonesia Sejahtera Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran Perspektif: Jurnal Pendidikan dan Ilmu Bahasa IJAE
Fadilah Fadilah
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Other

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Connecting the Dots: Transcriptomic Approaches and Relationship between Myocardial Infarction and Breast Cancer Miftahul Khair Akbar; Fadilah Fadilah; Arief Aulia Rahman
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 25 No. 01 (2024): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol25-iss01/478

Abstract

Myocardial infarction, resulting from coronary blood vessel blockage, inflicts lasting damage on the heart muscle. Meanwhile, breast cancer ranks among the most diagnosed cancers, causing millions of deaths annually. Mouse model research suggests that myocardial infarction induces systemic changes, fostering cross-disease communication that expedites breast cancer. Using GEO2R for transcriptomic analysis, Cytoscape for protein-protein interaction (PPI), and EnrichR for enrichment analysis, we explored the myocardial infarction-breast cancer relationship with datasets from GEO. We identified 3,300 differentially expressed genes, including 6 commonly upregulated and 18 commonly downregulated genes. PPI and enrichment analyses revealed RAD51 genes associated with homologous recombination pathways (P-value 0.02032). Additionally, 4 genes (RAD51, KIF4A, DTL, and DLGAP5) were linked to CD105+ endothelial cells (P-value 0.00002216), connecting myocardial infarction and breast cancer. Nevertheless, further testing is needed for accurate results and to support this study's transcriptomic analysis.
Penguatan Kerukunan antar Umat Beragama Pasca Konflik di Tanjungbalai Sumatera Utara Abdul Gani Jamora Nasution; Silvana Bayu; Risma Handayani; Tia Anggraini Silalahi; Tivany Ramadhani; Fadilah Fadilah
YASIN Vol 2 No 6 (2022): YASIN: Jurnal Pendidikan dan Sosial Budaya
Publisher : Lembaga Yasin AlSys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/yasin.v2i6.739

Abstract

The Unitary State of the Republic of Indonesia (NKRI) has various ethnicities, races, and religions. Likewise the diversity that exists in the city of Tanjungbalai, the people of Tanjungbalai have a population of 108,202 people, and in Asahan Regency a population of 884,594 people. They live side by side with various other ethnic groups, such as the Toba Batak, Mandailing, Minangkabau, and Javanese. The majority of the population of the city of Tanjungbalai adhere to Islam, up to 84.67 people, the rest adhere to Protestant Christianity, Buddhism and Catholicism. But behind that, there were many disparities between religions that ended in riots. This study uses a descriptive qualitative approach. The qualitative research method is a research method that places more emphasis on aspects of understanding in depth on a problem rather than looking at problems for generalization research. In strengthening inter-religious harmony in Tanjungbalai, there have been several steps taken by both the government and religious leaders, both Islamic and Chinese leaders. This step also aims to make the people of Tanjungbalai a harmonious and more peaceful society in carrying out their daily lives.
Co-Authors Abdul Bashit Al Fikri Abdul Gani Jamora Nasution Amelia Rika Fadillah Anita Anggraeni Anna Surgean Veterini Arifin Seweng Arnawati Arnawati Awaluddin, Rizki Azizah Rachmawati Bambang Suprapto Candra Pratama Cindy ApriliaEkaPrasanty Darmawansyah Darmawansyah Debby Desmarini Diana Romdhoningsih Dopa Lista Fahisatul Jannah Fathurrohim Fathurrohim Feriawan Tan Fiza Asri Fauziah Habibah Hera Damayanti Khairunisa Khairunisa Luluk Yunaini Mafruroh Mafruroh Malika Diah Puspita Sari Miftahul Khair Akbar Mohammad Ali Muhammad Ali Murdani Abdullah Novia Dewi Nur'asiah Nur'asiah Nursaidah Ahmad Puji Sari R. Bilqis Bunga Nirwana Rachmat Setiyadi Rahman, Arief Aulia Rahmawati Andayani Ridwan Tohopi Riskia Putri Risma Handayani Rizki Amalia Rizki Amalia Roni Priyanda Rosdiana Dwiyanti Sakti Hutabarat Saniati Saniati Santi Tri Wijayanti Silvana Bayu Sisi Anoli Putri Siti Khaerunnisa Sofy Meilaini Sumarta Dinata Susanti Susanti Tia Anggraini Silalahi Tivany Ramadhani Tiwi Tamara Tri Agina Sapira Usiono Usiono Winda Amelia Putri Yuani Setiawati