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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Biomedika Mandala of Health : A Scientific Journal Medical and Health Journal Oftalmologi: Jurnal Kesehatan Mata Indonesia Jurnal Widya Medika
Nafiisah, Nafiisah
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Library & Information Science Medicine & Pharmacology Nursing Public Health

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CORRELATIONS OF CADMIUM EXPOSURE WITH THE UREUM AND CREATININE SERUM LEVELS IN BATURADEN ORNAMENTAL PLANT FARMERS Nafiisah, Nafiisah; Laksana, Agung Saprasetya Dwi; Mulyanto, Joko
Biomedika Vol 12, No 2 (2020): Biomedika Agustus 2020
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v12i2.10416

Abstract

ABSTRACT  Baturaden ornamental plant farmers use pesticides and fertilizers containing cadmium to increase growth and plant diseases control. Cadmium is a very toxic heavy metal. Small doses of cadmium exposure in over a long time through respiratory tract, digestion, and skin penetration causes a workload on the kidneys. It resulting kidney damage that characterized by increased ureum and creatinine serum levels. The aimed of this study was determine the correlation of cadmium exposure to kidney function in terms of urea and creatinine serum levels. The research design was an observational analytic approach with cross sectional method. The respondents were 43 farmers. Research data were collected by interviews, measured the  urea and creatinine serum levels, also the cadmium urine levels. Data were analyzed by Spearman test. The results showed that there was a weak significant correlation between cadmium urine to ureum (r= 0.399 and p= 0.008) and creatinine serum levels (r= 0.331 and p= 0.03). We concluded that cadmium exposured correlated with increased ureum and creatinine serum levels.Keywords: Cadmium, Urea Serum Level, Creatinine Serum Level, Ornamental Plant Farmers                                                                                                       ABSTRAK Petani tanaman hias di Baturaden menggunakan pestisida dan pupuk yang mengandung kadmium untuk meningkatkan pertumbuhan dan pengendalian penyakit tanaman. Kadmium adalah logam berat yang sangat beracun. Paparan kadmium dosis kecil dalam jangka waktu yang lama melalui saluran pernafasan, pencernaan, dan penetrasi kulit menyebabkan beban kerja pada ginjal. Hal tersebut mengakibatkan kerusakan ginjal yang ditandai dengan peningkatan kadar ureum dan kreatinin serum. Penelitian ini bertujuan untuk mengetahui hubungan paparan kadmium terhadap fungsi ginjal ditinjau dari kadar ureum dan kreatinin serum. Desain penelitian adalah observasional analitik dengan metode cross sectional. Respondennya sebanyak 43 petani. Pengumpulan data penelitian dilakukan dengan wawancara, pengukuran kadar urea dan kreatinin serum, serta kadar kadmium urin. Data dianalisis dengan uji Spearman. Hasil penelitian menunjukkan bahwa terdapat hubungan bermakna yang lemah antara kadar kadmium urin dengan kadar serum ureum (r= 0,399 dan p= 0,008) dan kreatinin (r= 0,331 dan p= 0,03). Kami menyimpulkan bahwa paparan kadmium berkorelasi dengan peningkatan kadar ureum dan kreatinin serum.Kata Kunci: Kadmium, Kadar Ureum Serum, Kadar Kreatini Serum, Petani Tanaman Hias
THE PREVALENCE OF HYPERTENSION AMONG YOUNG ADULT PATIENTS AT KLINIK SOEDIRMAN PURWOKERTO Sinensis, Rizki Amelia; Wicaksono, Madya Ardi; Nafiisah, Nafiisah; Firinda, Rizma Haidif; Kamal, Isran
Medical and Health Journal Vol 4 No 2 (2025): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2025.4.2.14926

Abstract

Hypertension is a growing public health problem, particularly among young adults. This study aims to determine the prevalence of hypertension among young adult patients at Klinik Soedirman Purwokerto. The study uses a quantitative descriptive design with a sample of all patients aged 18-24 years who accessed healthcare services at the clinic from March to September 2024. The results show that the majority of patients were female (72.51%), with the most frequent age group being 20 years (29.75%). Recorded diagnoses of hypertension included both essential and secondary hypertension, with one case of both types found in a 20-year-old female patient. Risk factors contributing to hypertension in young adults include unhealthy lifestyle factors such as high salt diet, lack of physical activity, alcohol consumption, and smoking habits. These findings indicate the need for more effective preventive programs among young adults, such as promoting healthy lifestyles and routine blood pressure screening. This study can serve as a basis for designing hypertension prevention measures among students, particularly at Jenderal Soedirman University
Skabies di Antara Penyakit Kulit: Studi Prevalensi di Klinik Pratama Soedirman Tahun 2024 Firinda, Rizma Haidif; Wicaksono, Madya Ardi; Sinensis, Rizki Amelia; Nafiisah, Nafiisah; Kusdaryanto, Wahyu Dwi; Ihtiaringtyas, Suci
Jurnal Ilmu Kedokteran Vol 19, No 1 (2025): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v19i1.2025.84-89

Abstract

Scabies is a skin disease caused by infestation of the parasitic mite Sarcoptes scabiei, which penetrates the skin and reproduces by laying eggs. Although often regarded as a common and non-severe condition, scabies is classified as a neglected skin disease on a global scale. This study aims to determine the prevalence of scabies in relation to the total number of skin diseases diagnosed at the Soedirman Primary Outpatient Clinic. A descriptive research method was employed, utilizing patient medical records from March to September 2024. Data were collected based on ICD-10 diagnostic codes, including both scabies and other dermatological conditions. The results showed that there were 13 recorded cases of scabies (5.05%) out of a total of 257 diagnosed skin diseases. This prevalence closely aligns with the national prevalence of scabies in Indonesia. Variations in prevalence may be influenced by social and environmental factors, with higher transmission rates occurring in densely populated areas and among individuals with frequent close contact. Preventive measures include health education, personal hygiene, and improved environmental sanitation.
Karakteristik dan Gambaran Hasil Tajam Penglihatan pada Operasi Pterigium di Rumah Sakit Khusus Mata Purwokerto Tahun 2023 Nafiisah, Nafiisah; Setyawan, Agus
Oftalmologi : Jurnal Kesehatan Mata Indonesia Vol 7 No 1 (2025): Oftalmologi: Jurnal Kesehatan Mata Indonesia
Publisher : Pusat Mata Nasional Rumah Sakit Mata Cicendo Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ojkmi.v7i1.80

Abstract

Pendahuluan: Pterigium adalah pertumbuhan jaringan fibrovaskular pada konjungtiva bulbar yang dapat menyebabkan gangguan penglihatan. Penelitian ini bertujuan untuk mengidentifikasi karakteristik dan hasil tajam penglihatan pascaoperasi pada pasien pterigium di RS Khusus Mata Purwokerto selama tahun 2023. Metode: Penelitian deskriptif retrospektif ini melibatkan 44 pasien yang telah menjalani operasi pterigium. Data yang dianalisis meliputi karakteristik jenis kelamin, usia, lokasi tempat tinggal, pekerjaan, derajat dan lateralisasi pterigium, penyakit penyerta, teknik operasi dan ketajaman penglihatan. Hasil: Hasil menunjukkan mayoritas pasien adalah perempuan berusia 60-74 tahun yang tinggal di pedesaan sebagai ibu rumah tangga. Distribusi antara pterigium unilateral dan bilateral seimbang dengan seluruhnya derajat 4. Sebagian besar pasien memiliki penyakit penyerta seperti hipertensi. Sebanyak 9 pasien mengalami perbaikan tajam penglihatan yang signifikan setelah operasi dengan sebagain besar menggunakan teknik conjunctival autograft. Kesimpulan: Intervensi bedah berperan penting dalam mengatasi gangguan penglihatan yang disebabkan oleh pterigium.
DESCRIPTION OF DISEASES SUFFERED BY MOTHERS AND CHILDREN AT THE AGE OF 0-3 YEARS WITH HEARING LOSS AT MARGONO SOEKARJO PURWOKERTO HOSPITAL Fahrizal, Eky Danu; Kusdaryanto, Wahyu Dwi; Nafiisah, Nafiisah; Agustina, Nenden Nursyamsi; Darmawan, Anton Budhi
Mandala Of Health Vol 17 No 1 (2024): Mandala of Health
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2024.17.1.7908

Abstract

Hearing loss is difficult to detect in infants and children. It can inhibit cognitive, emotional, language, and communication development. Therefore, hearing loss needs to be immediately examined to minimize its impacts. It is essential to recognize the disease suffered by infants and children, especially those with a history of hearing loss during the pranatal, perinatal, and postnatal periods for early examinations. This study aimed to evaluate diseases characteristic suffered by children with hearing loss aged 0-3 years at RSUD Margono Soekarjo, Purwokerto. This research was descriptive, using secondary data. The analysis used was univariate. Hearing loss in children during; the pranatal (15.4%) could be caused by a family history of the disease, TORCH infection, and preeclampsia; during the perinatal (70,3%) could be caused by low birth weight, prematurity, hyperbilirubinemia, and neonatal asphyxia, and; during the postnatal period (14.3%) could be caused by the use of mechanical ventilators and febrile seizures. The disease character in children aged 0-3 years with hearing loss at RSUD Margono Soekarjo Purwokerto are disease during pranatal, perinatal, and postnatal periods
PENGARUH PAPARAN CAHAYA BIRU PADA PERANGKAT DIGITAL TERHADAP KESEHATAN MATA: TINJAUAN LITERATUR Nafiisah, Nafiisah; Setyawan, Agus
Mandala Of Health Vol 17 No 2 (2024): Mandala of Health: a Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2024.17.2.12969

Abstract

Exposure to blue light from digital devices such as smartphones, tablets, and computers has become a major concern for eye health. Blue light, with wavelengths between 400-500 nanometers, can penetrate deeper into the eye and potentially cause retinal damage. This article reviews various studies assessing the impact of blue light on eye health, including the risks of developing computer vision syndrome, myopia, and age-related macular degeneration (AMD). Although the use of blue-blocking lenses has been suggested as a preventive measure, its long-term effectiveness requires further investigation. Other strategies, such as screen time regulation and the use of blue light-reducing software, are also analyzed as part of efforts to mitigate the negative effects of blue light. The findings from this review indicate that while there is potential risk from blue light exposure, more research is needed to develop more effective preventive strategies and to understand its long-term impact on eye health.
PENGARUH PENGGUNAAN BUKU SAKU SEBAGAI MEDIA EDUKASI TERHADAP KEPATUHAN DIET DAN KADAR GULA DARAH PUASA (GDP) PADA PASIEN DIABETES MELITUS TIPE 2 DI KECAMATAN SUMBANG BANYUMAS Burkon, Lily Kusumasita; Nafiisah, Nafiisah; Ernawati, Dwi Arini; Putri, Chilma Al Aini
Mandala Of Health Vol 17 No 2 (2024): Mandala of Health: a Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2024.17.2.12984

Abstract

Background: Indonesia ranks 6th highest with Diabetes mellitus (DM) in the world in 2019. There are complications occur due to DM type 2. To prevent this, fasting blood sugar (GDP) monitoring and patient diet by using pocketbooks as an educational compliance can be carried out. Objective: To identify the effect of using pocketbooks as an educational medium in monitoring dietary compliance and GDP levels of type 2 DM patients in Sumbang. Methodology: Quasi-Experimental method was used with pretest – posttest design on 100 DM Prolanis patients at Puskesmas Sumbang 1 and 2 which were divided into two groups. Both groups were given different education where the treatment group used a pocketbook while the control group was given oral education. Results: In the pretest-posttest data of GDP levels, there were differences in results before and after the intervention in the treatment group (Wilcoxon test, p = 0.000) while the control group gave no difference in results before and after the intervention (Wilcoxon test, p = 0.090). In the pretest – posttest diet adherence data, there were differences in results before and after the intervention in the treatment group (Paired T Test, p = 0.000) while the control group gave no difference in results before and after the intervention (Paired T Test, p = 0.074). The Mann Whitney test and the unpaired T test showed that the two variables had a significant difference (p = 0.000). Conclusion: there is an effect of pocketbook education intervention on GDP levels and dietary compliance of type 2 DM patients in Sumbang District, Banyumas Regency which reduces GDP levels and improves respondents' dietary compliance.
ANTIDIABETIC EFFECT TEST OF CENTELLA ASIATICA EXTRACT IN HYPERCHOLESTEROLEMIA RAT MODELS Nafiisah, Nafiisah; Aini Gumilas, Nur Signa; Harini, Ika Murti
JURNAL WIDYA MEDIKA Vol. 10 No. 2 (2024): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v10i2.6031

Abstract

Introduction: High blood sugar levels can lead to hypercholesterolemia, a condition where cholesterol levels in the blood exceed normal values. The active compounds in Centella asiatica (pegagan) have the potential to act as antidiabetic agents by stimulating insulin production by pancreatic beta cells. Objective: This study aims to determine the effect of Centella asiatica extract on lowering fasting blood glucose (FBG) levels in hypercholesterolemia rat models. Methods: Thirty-two test animals were divided into 4 groups: normal control, negative control, positive control (Simvastatin 1.8 mg/kgBW/day), and treatment (Centella asiatica extract 500 mg/kgBW/day). Hypercholesterolemia was induced using 2% cholesterol and 0.2% cholic acid. FBG measurement was performed after 5 weeks of administration of Centella asiatica extract and Simvastatin. Data analysis used one-way ANOVA and post hoc Bonferroni tests. Results: The mean FBG (mg/dL) in P1=70.85±1.89; P2=151.82±2.91; P3=92.34±1.86; and P4=83.89±2.17. The one-way ANOVA test results showed statistically significant differences (p
Co-Authors Agung Saprasetya Dwi Laksana, Agung Saprasetya Dwi Agus Setyawan Agustina, Nenden Nursyamsi Aini Gumilas, Nur Signa Burkon, Lily Kusumasita Darmawan, Anton Budhi Ernawati, Dwi Arini Fahrizal, Eky Danu Firinda, Rizma Haidif Harini, Ika Murti Ihtiaringtyas, Suci Joko Mulyanto, Joko Kamal, Isran Kusdaryanto, Wahyu Dwi Madya Ardi Wicaksono, Madya Ardi Putri, Chilma Al Aini Sari, Nahwa Aulia Kartika Sinensis, Rizki Amelia