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All Journal Publikasi Pendidikan Jurnal Kesehatan Jurnal Aisyah : Jurnal Ilmu Kesehatan Jurnal Pengabdian Kepada Masyarakat Ungu ( Abdi Ke Ungu) Jurnal Ilmiah Wahana Pendidikan JIFI (Jurnal Ilmiah Farmasi Imelda) JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Journal of Innovative and Creativity International Journal of Contemporary Sciences (IJCS)
Suswidiantoro, Vicko
Universitas Aisyah Pringsewu
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Electrical & Electronics Engineering Health Professions Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Standarization of Simplicia and Extracts from Guava leaf (Psidium guajava) Suswidiantoro, Vicko
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 10, No 1 (2025): March
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v10i1.2969

Abstract

The guava leaf (Psidium guajava) is a plant with promise for development as a natural remedy. This work seeks to develop standardization encompassing both specific and non-specific properties of simplicia and extracts. The procedure for establishing standardization parameters pertains to the Indonesian Herbal Pharmacopoeia and General Standard Extracts Parameters.  The organoleptic standardization of simplicia is characterized by a brownish-green hue, a unique aroma, and a bitter taste.  The water content test revealed a result of 50.4%; the free ethanol content; and a total ash content of 4.06%; the extract standardization indicates a viscous green-black extract with a strong odor and a bitter flavor. The leaves of Psidium guajava include tannins, flavonoids, saponins, and terpenoids.  Additional statistics include an extract yield of 20.96%, a moisture content of 40.93%, and a total ash content of 41.18%. The standardization specifications for total ash content and moisture content are not mandated by Media Materia Indonesia or the Republic of Indonesia Drug and Food Control Center)
Uji Efektivitas Antibakteri Ekstrak Daun Sirih Hijau (Piper Betle L.) Terhadap Pertumbuhan Bakteri Staphylococcus Aureus Sucipto, Ajeng Afriliana; Dwiningrum, Riza; Wibowo, Catur Ari; Suswidiantoro, Vicko
Jurnal Ilmiah Wahana Pendidikan Vol 11 No 5.A (2025): Jurnal Ilmiah Wahana Pendidikan 
Publisher : Peneliti.net

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Abstract

This research is at testing the effectiveness of a variable a laboratory experimental research with a disc diffusion method on nutrient agar media with 5 treatments in the form of negative control, positive control, 40% betel leaf extract, 50% betel leaf extract, and 60% betel leaf extract. Data analysis was carried out with the Kruskal Wallis test then continued with the Post Hoc test with the Mann Whitney test. The Kruskal Wallis test results obtained a significance value of 0.020 value (sig) <0.05, so it can be said that there is a significant difference in the average diameter of the inhibition zone between the treatment groups. The Mann Whitney test results show a value (sig) > 0.05 for positive control, concentrations of 40%, 50% and 60% have significant effectiveness against the growth of Staphylococcus aureus bacteria. In this study, 40% concentration has an average value of 18.87 mm with a standard deviation of 2.13 mm, 50% concentration has an average value of 19.75 mm with a standard deviation of 4.58 mm, and 60% concentration has an average value of 19.87 mm and a standard deviation of 2.13 mm which shows that it is included in the strong category. T his shows that green betel leaves (Piper betle L.) can be used as an antibacterial.
Hubungan Tingkat Pengetahuan Masyarakat Terhadap Perilaku Penggunaan Antibiotik Di Desa Setia Bumi Kecamatan Seputih Banyak Kabupaten Lampung Tengah Septiana, Elen; Pratiwi, Mida; Yanti, Erna; Suswidiantoro, Vicko
Jurnal Ilmiah Wahana Pendidikan Vol 11 No 4.D (2025): Jurnal Ilmiah Wahana Pendidikan 
Publisher : Peneliti.net

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Abstract

Meningkatnya jumlah penyakit infeksi membuat antibiotik juga meningkat. Salah satu faktor yaitu kurangnya pengetahuan masyarakat terkait penggunaan antibiotik. Penelitian ini bertujuan untuk mengetahui hubungan antara tingkat pengetahuan masyarakat terhadap perilaku penggunaan antibiotik yang baik dan benar serta menghindari risiko resistensi antibiotik. Jenis penelitian ini deskriptif dengan metode cross sectional menggunakan 19 item pernyataan. Sampel dalam penelitian ini sebesar 98 responden yang berada di Desa Setia Bumi Kecamatan Seputih Banyak Kabupaten Lampung Tengah dan yang memenuhi kriteria inklusi dan eksklusi. Data dianalisis dengan menggunakan uji-t (independen sampel t-test) . Hasil yang diperoleh untuk tingkat pengetahuan kurang 21,4%, cukup 63,3% dan baik 15,3% sedangakan perilaku penggunaan antibiotik kurang 19,4%, cukup 67,3% dan baik 13,3%. Pada hasil bivariat diperoleh signifikan p = 0,000 yang artinya nilai signifikan lebih kecil dari 0,05 (p<0,05) maka dapat disimpulkan bahwa terdapat hubungan antara tingkat pengetahuan dengan perilaku penggunaan antibiotik di Desa Setia Bumi Kecamatan Seputih Banyak Kabupaten Lampung Tengah. Kesimpulan dari penelitian hubungan tingkat pengetahuan masyarakat terhadap perilaku penggunaan antibiotik di Desa Setia Bumi Kecamatan Seputih Banyak Kabupaten Lampung Tengah secara umum atau sebagian besar responden memiliki pengetahuan dan perilaku yang cukup terhadap penggunaan antibiotik.
Pengaruh Penyuluhan Terhadap Tingkat Kepatuhan Penggunaan Obat Pada Pasien Prolanis Hipertensi Di Klinik Shella Medika Saputra, Cahya Agung; Suswidiantoro, Vicko; Dwiningrum, Riza; Putri, Diah Kartika
Jurnal Ilmiah Wahana Pendidikan Vol 11 No 6.B (2025): Jurnal Ilmiah Wahana Pendidikan 
Publisher : Peneliti.net

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Abstract

Hipertensi salah satu penyakit dimana tekanan darah sistolik kurang lebih 140 mmhg dan tekanan darah lebih dari 90 mmHg. Prolanis merupakan inisiatif aktif yang melibatkan peserta, penyedia layanan kesehatan dan BPJS (Badan Penyelenggara Jaminan Sosial) Kesehatan untuk mengobati penyakit kronis dan mencapai kualitas hidup optimal melalui layanan kesehatan. Penelitian ini bertujuan untuk Mengetahui pengaruh penyuluhan terhadap tingkat kepatuhan penggunaan obat pada pasien prolanis hipertensi di Shella Medika. Metode penelitian ini menggunakan quasi eksperimental pre-post test dengan pendekatan Cross-sectional kuantitatf. Penelitian ini menggunakan sebanyak 30 responden. Berdasarkan hasil penelitian pre-test diperoleh tingkat kepatuhan pasien hipertensi di peroleh 87% sehingga perlu dilakukan penyuluhan, setelah dilakukan penyuluhan diperoleh hasil 60% dan di analisis mengggunakan paired sample T-test p-value 0,003 dan terdapat perbedaan dari uji pillcount. Untuk mengetahui kepatauhan responden penelitian ini menggunakan uji pillcount, uji pillcount hasil perhitungan akan diperoleh hasil <80% masuk dalam kategori tidak patuh, dan hasil perhitungan >80% termasuk dalam kategori patuh. Penelitian yang sudah dilakukan dapat disimpulkan bahwa terdapat pengaruh penyuluhan tingkat kepatuhan penggunaan obat hipertensi dan dapat dikatakan bahwa terdapat pengaruh penyuluhan tingkat kepatuhan penggunaan pada pasien hipertensi
Formulasi dan Evaluasi Sediaan Body Scrub Kombinasi Ekstrak Daun Salam (Syzygium polyanthum (Wight.) Walp. dan Beras Putih (Oryza sativa L. ) Sebagai Antioksidan Dwiningrum, Riza; Pratiwi, Mida; Suswidiantoro, Vicko; Amanda, Clarissa Helmavicha
Journal of Innovative and Creativity Vol. 5 No. 2 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i2.2247

Abstract

Body scrub is a cosmetic that acts as an exfoliator, which has the ability to remove dead skin cells and provide protection to the skin from free radical attacks. One of the natural ingredients that can be used as raw material for body scrub is bay leaf (Syzygium polyanthum (Wight.) Walp) and white rice (Oryza sativa L.) with flavonoids, tocopherols, and tocotrienols that act as natural antioxidants. The study purpose was: This study aims to determine the physical quality characteristics and antioxidant activity of bay leaf and white rice extract body scrub preparations using UV-Vis spectrophotometry. Materials and methods. The method used in the study was experimental in the laboratory by making three formulations of body scrub concentrations FI (3%,10%), FII (6%,10%), and FIII (9%,10%). Results: The results of the study stated that the three formulas met the requirements of the physical quality test, but did not meet the protective power test and the preparations had different antioxidant values, where the best formula that had a very strong antioxidant activity value was in formula III with an IC50 value obtained of 45.452, which was included in the very strong category. Conclusions. The research conducted is expected to be an initial reference for further researchers to conduct pharmacological activity tests such as antibacterial or anti-inflammatory in vivo to support the further benefits of the preparations made.
Formulasi Dan Uji Mutu Fisik Sediaan Krim Dari Ekstrak Etanol Daun Sirsak (Annona Muricata Linn) Sebagai Pelembab Kulit Dwiningrum , Riza; Arifah , Linatul; Pratiwi , Mida; Suswidiantoro, Vicko
Journal of Innovative and Creativity Vol. 5 No. 2 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

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Abstract

Kulit kering merupakan kondisi yang sering terjadi akibat menurunnya kadar air dan natural moisturizing factor (NMF) pada permukaan kulit. Salah satu upaya untuk mengatasi permasalahan ini adalah dengan penggunaan pelembab berbahan dasar alami. Daun sirsak (Annona muricata Linn) diketahui memiliki kandungan senyawa bioaktif seperti flavonoid, tanin, dan alkaloid yang berfungsi sebagai antioksidan dan dapat membantu meningkatkan kelembapan kulit. Penelitian ini bertujuan untuk memformulasikan dan mengevaluasi mutu fisik sediaan krim dari ekstrak etanol daun sirsak (Annona muricata Linn) sebagai pelembab kulit. Jenis penelitian ini adalah eksperimental laboratorium. Ekstrak daun sirsak diformulasikan dalam bentuk sediaan krim dengan konsentrasi 10%, 15%, dan 20%, serta dibandingkan dengan kontrol positif (Dorskin) dan kontrol negatif (blanko). Hasil penelitian menunjukkan bahwa seluruh formula krim memiliki mutu fisik yang memenuhi standar, seperti tampilan organoleptis yang stabil, homogenitas merata, pH berada dalam kisaran aman untuk kulit (5,84–6,39), daya sebar optimal (5,3–6,4 cm), daya lekat sesuai standar (3,8–4,9 detik), viskositas stabil (3.400–7.000 cP), dan tidak mengalami perubahan signifikan selama uji stabilitas. Formula dengan konsentrasi 20% ekstrak daun sirsak (F3) menghasilkan rata-rata peningkatan kelembapan kulit sebesar 61,87%, yang merupakan hasil terbaik di antara semua formula. Hasil uji ANOVA menunjukkan adanya perbedaan signifikan antar kelompok konsentrasi (p = 0,000), yang menandakan bahwa peningkatan konsentrasi ekstrak daun sirsak berpengaruh nyata terhadap kelembapan kulit. Disarankan agar ekstrak daun sirsak digunakan dalam konsentrasi optimal sebagai bahan aktif alami dalam sediaan krim pelembab kulit, serta dilakukan uji lanjutan untuk menilai keamanan dan stabilitas jangka panjang.
ESTUTI: Ethnomedicine and Transformation of Ice Cream to Prevent Stunting Using Family Medicinal Plants in Tanggamus Putri, Diah Kartika; Lestari, Fina Aulika; Miftausakina, Taufiki; Nurazizah, Amalia Siti; Saputra, Adi; Suswidiantoro, Vicko; Safutri, Wina
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 10, No 1 (2025): March
Publisher : Universitas Aisyah Pringsewu

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Abstract

The stunting prevalence rate for Lampung Province based on the 2022 SSGI averages 15.2% and Tanggamus Regency is ranked fourth with the highest stunting prevalence, namely 20.4%. This research aims to use TOGA as a spearhead for treating stunting in toddlers using Moringa leaves and ginger rhizomes. Moringa leaves (Moringa Oleifera Lam.) can be used as a potential alternative source of protein and calcium to meet children's nutritional needs. The ESTUTI formulation is divided into 3 formulations with differences in Moringa leaf extract and ginger, namely 25gr/100ml water, 50gr/100ml water, and 75gr/100ml water. Tests in this research include organoleptic tests, hedonic tests and melting point tests. The results show that the most preferred "ESTUTI" formulation is F1 with the formula Moringa leaves: ginger 25gr/100ml water. The combination of ginger and Moringa leaves is rich in nutritional value as an anti-stunting agent which the community responded well to during outreach. So it is hoped that it will be able to provide information on snacks as functional foods that have new qualities and qualities as anti-stunting by utilizing plants that grow abundantly around and developing the community's innovation and entrepreneurship experience.Key words: Curcuma xanthorriza; Ethnomedicine; Formulation; Ice cream; Moringa oleifera Lam; Stunting 
Antioxidant Activity Test of Combination of Butterfly Pea Flower Extract (Clitoria ternatea L.) and Ashoka Leaves (Ixora coccinea L.) Using DPPH Method Safitri, Indah; Suswidiantoro, Vicko; Pratiwi, Mida; Dwiningrum, Riza
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 2 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i2.4084

Abstract

Excess free radicals trigger oxidative stress that accelerates skin aging and increases the risk of degenerative diseases. Efforts to counter it require safe and effective antioxidants based on natural ingredients. Telang flowers (Clitoria ternatea L.) and asoka leaves (Ixora coccinea L.) are known to be rich in flavonoids and phenolates, but data on the effectiveness of the combination of the two are limited. This study aims to assess the antioxidant activity of the mixture of the extracts of the two plants. Ethanol extracts of telang flowers and asoka leaves are prepared, the yield is determined, then phytochemical screening confirms the presence of alkaloids, flavonoids, saponins, and tannins. Anti-radical activity was tested by the DPPH method at three ratios (25 %:75 %, 50 %:50 %, 75 %:25 %) and compared with quercetin (2–10 ppm) as a positive control. The value of IC₅₀ is calculated through linear regression. The 50%:50% mixture showed the highest potency (IC₅₀ = 2.3237 ppm) and was classified as "very strong", close to quercetin (0.7631 ppm) and much better than each of the single extracts reported in the previous study (IC₅₀ telang flower 32.23 ppm; asoka leaf 150.12 ppm). These results indicate a synergy between the two bioactive compounds in simplicia in neutralizing free radicals. Conclusion: the combination of telogen flower–asoka leaf extract has the potential to be developed as a superior natural antioxidant for pharmaceutical or cosmetic products. Further research is recommended to focus on the fractionation of dominant compounds, formulation stability tests, and pre-clinical safety evaluation to in vivo applications.
Antibacterial Activity Test of the Combination of Citronella Leaf Extract (Cymbopogon nardus L.) and Lime Leaf Extract (Citrus aurantifolia Swingle) Against the Growth of Streptococcus mutans Aini, Sarifatul; Safutri, Wina; Suswidiantoro, Vicko
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 2 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i2.4213

Abstract

Dental caries infection is one of the most common dental health problems caused by Streptococcus mutans bacteria. The use of synthetic antibiotics in the treatment of infection risks causing bacterial resistance, so a safer alternative, natural treatment, is needed. Citronella leaves (Cymbopogon Nardus L.) and lime leaves (Citrus aurantifolia Swingle) contain active compounds such as alkaloids, flavonoids, saponins, and tannins that have antibacterial activity. This study aims to determine the effectiveness of the combination of extracts of the two plants against the growth of Streptococcus mutans. The type of research used is laboratory experimental with Completely Randomized Design, consisting of 5 treatments and 4 repetitions. The antibacterial test was carried out by disc diffusion method using a combination concentration of extracts P1 (2.5%: 7.5%), P2 (12.5%: 5%), and P3 18.75%: 2.5%), negative control (distilled water), and positive control (tetracycline). The test results showed that the P3 produced the best inhibition against Streptococcus mutans with an average inhibition zone of (6.02 ± 0.46) mm and fell into the moderate category. Data analysis using the ANOVA test resulted in a significance value of p = 0.000 (p < 0.05), which indicated there were significant differences between treatments. Further tests using Tukey HSD showed that the P3 was significantly different compared to the other treatments. Thus, the combination of citronella and lime leaf extracts is proven to have potential as a natural antibacterial against the growth of Streptococcus mutans bacteria.
ANTIFUNGAL ACTIVITY TEST OF THE COMBINATION OF PAPAYA LEAF (Carica papaya L.) AND BASIL LEAF (Ocimum x africanum Lour) EXTRACTS AGAINST THE GROWTH OF Candida albicans Pratama, Dimas Feriza Pratama; Suswidiantoro, Vicko; Daskar, Annajim; Safutri, Wina
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 2 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i2.4214

Abstract

Fungal infections are common health problems, one of which is caused by Candida albicans. The use of synthetic antifungal agents in treatment can lead to side effects and resistance risks, thus necessitating safer natural alternatives. Papaya leaves (Carica papaya L.) and basil leaves (Ocimum x africanum Lour) are known to contain active compounds such as flavonoids, alkaloids, saponins, steroids, and tannins, which have potential as antifungal agents. The combination of these two plant extracts was used to enhance antifungal effectiveness through possible synergistic effects of their active compounds, with the expectation of yielding a more optimal inhibitory effect against Candida albicans. This study aimed to determine the effectiveness of a combination of papaya and basil leaf extracts in inhibiting the growth of Candida albicans. The research was conducted experimentally using a Completely Randomized Design (CRD) with five treatment groups and four replications. The antifungal activity was tested using the disc diffusion method with extract combinations formulated in 96% ethanol at concentrations of (18.75% : 18.75%), (37.5% : 12.5%), and (56.25% : 6.25%), as well as a negative control (aquadest) and a positive control (ketoconazole 15 μL). One-Way ANOVA analysis showed a significant difference between treatments (p < 0.05). Further analysis using Tukey HSD revealed no statistically significant differences between the three extract combination groups. However, P3 exhibited the highest inhibition zone (4.73 ± 0.91 mm), while P1 showed the lowest (3.45 ± 0.65 mm), and P2 was intermediate (3.98 ± 0.65 mm). All three combinations showed statistically significant differences compared to the negative control (0 mm) and the positive control (6.50 ± 0.83 mm). Thus, although no significant difference was observed between the combination groups, all combinations demonstrated statistically significant antifungal activity against Candida albicans compared to the negative control. In conclusion, the combination of papaya and basil leaf extracts possesses antifungal activity against Candida albicans, although the effectiveness is not yet optimal. Further research is recommended with increased extract concentrations and development into pharmaceutical dosage forms such as gels or ointments as alternative topical antifungal treatments.
Co-Authors Abdul Mun&#039;ím Abdul Mun’im Adi Saputra Aini, Sarifatul Alhauri, M.Syarif Amanda, Clarissa Helmavicha Anggun Fitria Arifah , Linatul Artadevy, Nadhila Fahira Bastian, Arif Alexander Bayu Satriawan, Ahmad Damayanti Abdul Karim, Dewi Daskar, Annajim Deswita, Dwi Diah Kartika Putri Diah Kartika Putri Dimas Thoriq Muhammad Iqbal Dwiningrum , Riza Eka Pratiwi Yunianti Fadia Zahra, Alya Fadlina Chany Saputri Fikriya Ridlawati Gustianing, Defy Humayroh, Suci Iga Mayola Pisacha Islam, Haikal Nur Kaka Widi Rahayu Kartika, Jelita Katika Putri, Diah Khoiri, Ahmad Zul Lestari, Fina Aulika Mayola Pisacha, Iga Mida Pratiwi Mida Pratiwi Miftausakina, Taufiki Muhammad Ridwan Mun'im, Abdul Novita, Riska Reza Nurazizah, Amalia Siti Pisacha, Iga Mayola Pratama, Dimas Feriza Pratama Pratiwi , Mida Puspita, Cici Chandra Putri, Diah Karika Putri, Diah Kartika putri, Salsa della ananta Riza Dwiningrum Riza Dwiningrum Riza Dwiningrum, Riza Rosanti, Afi Sania Safitri, Indah Saputra, Andika Wahyu Saputra, Cahya Agung Sari, Triyani Anggun Sari Sari, Yuhana Satriawan, Ahmad Bayu Selviyana, Eka Septiana, Elen Sucipto, Ajeng Afriliana Sutomo, Ahmad Syaifurrahman, Amir Tanjung, Salsabila Adelia Tias Eka Rahmawati Wibowo, Catur Ari Wina Safutri Wina Safutri Yanti, Erna Yeni Aryanti Zahra, Annisa