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All Journal Publikasi Pendidikan Jurnal Kesehatan Jurnal Aisyah : Jurnal Ilmu Kesehatan Jurnal Pengabdian Kepada Masyarakat Ungu ( Abdi Ke Ungu) Jurnal Ilmiah Wahana Pendidikan JIFI (Jurnal Ilmiah Farmasi Imelda) JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Journal of Innovative and Creativity International Journal of Contemporary Sciences (IJCS)
Suswidiantoro, Vicko
Universitas Aisyah Pringsewu
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Electrical & Electronics Engineering Health Professions Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Formulasi Sediaan Lotion Fraksi Etanol Kulit Coklat (Theobroma cacao L) Sebagai Antioksidan Humayroh, Suci; Rosanti, Afi Sania; Putri, Diah Kartika; Suswidiantoro, Vicko
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.3629

Abstract

ABSTRACT Kulit salah satu organ terluar tubuh yang rentan mengalami kerusakan akibat paparan radikal bebas dari sinar ultraviolet dan faktor lingkungan lainnya. Kondisi tersebut dapat memicu kerusakan kulit, penuaan dini hingga kanker kulit, sehingga diperlukan perlindungan kulit dengan senyawa antioksidan. Kulit coklat (Theobroma cacao L) diketahui mengandung flavonoid dan polifenol yang berpotensi sebagai antioksidan alami. Penelitian ini bertujuan untuk memformulasikan sediaan lotion berbasis fraksi etanol kulit coklat serta menilai sifat fisik dan aktivitas antioksidan berdasarkan nilai IC50. Ekstraksi dilakukan melalui metode maserasi menggunakan etanol 96%, dan fraksinasi, kemudian diformulasikan dalam tiga konsentrasi, yaitu F1(0,05gr), F2(0,1gr), dan F3(0,2gr). Evaluasi mutu fisik mencakup uji organoleptik, homogenitas, pH, viskositas, daya sebar, daya lekat, dan daya proteksi, sedangkan uji aktivitas antioksidan menggunakan metode DPPH. Hasil sediaan lotion fraksi etanol kulit coklat memenuhi semua syarat mutu fisik yang tidak memenuhi syarat mutu fisik pada uji proteksi F1&2. Hasil aktivitas antioksidan sediaan lotion fraksi etanol F1 sedang (126,6 ppm), F2 sangat kuat (48,55 ppm), dan F3 sangat kuat (36,67 ppm). Kesimpulan pada penelitian ini menunjukkan hasil bahwa F3 memenuhi semua kriteria mutu fisik sediaan lotion dan memiliki kandungan antioksidan terbaik, Penelitian ini juga menjadi Upaya pemanfaatan limbah kulit coklat (Theobroma cacao L) sebagai bahan baku kosmetik yang ramah lingkungan sehingga dapat menjadi dasar untuk pengembangan produk kosmetik herbal yang efektif dan aman. Kata Kunci: Antioksidan, DPPH, IC50, kulit coklat, lotion ABSTRACT The skin is one of the outermost organs of the body that is vulnerable to damage caused by free radicals from ultraviolet radiation and other environmental factors. Such conditions may trigger skin damage, premature aging, and even skin cancer, thus requiring protection with antioxidant compounds. Cocoa shell (Theobroma cacao L.) contains flavonoids and polyphenols that have potential as natural antioxidants. This study aimed to formulate a lotion preparation based on the ethanol fraction of cocoa shell and to evaluate its physical properties and antioxidant activity based on IC50 values. Extraction was carried out by maceration using 96% ethanol, followed by fractionation, and the fraction was then formulated into three concentrations: F1(0.05gr), F2(0.1gr), and F3(0.2gr). Physical evaluations included organoleptic test, homogeneity, pH, viscosity, spreadability, adhesion, and protection, while antioxidant activity was tested using the DPPH method. The results showed that all lotion formulations met physical quality requirements, except that F1 and F2 did not meet the criteria in the protection test. Antioxidant activity of the ethanol fraction lotion was classified as moderate for F1 (126.6 ppm), and very strong for F2 (48.55 ppm) and F3 (36.67 ppm). In conclusion, F3 fulfilled all physical requirements and had the best antioxidant activity. This study also represents an effort to utilize cocoa shell waste (Theobroma cacao L.) as an eco-friendly cosmetic ingredient and a foundation for the development of safe and effective herbal cosmetic products. Keywords: Antioxidant, DPPH, IC50, cocoa shell, lotion
Hubungan Tingkat Pengetahuan Dan Kepatuhan Pasien Rawat Jalan Tentang Penggunaan Antibiotik Di Rsud Dr. H. Abdul Moeloek Provinsi Lampung Tahun 2025 Khoiri, Ahmad Zul; Suswidiantoro, Vicko; Pratiwi, Mida; Putri, Diah Kartika
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

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Abstract

Penyakit infeksi menjadi masalah kesehatan masyarakat yang penting khususnya di negara berkembang. Pengobatan lini pertama untuk mengatasi masalah tersebut adalah penggunaan antimikroba antara lain antibakteri/antibiotik, antijamur, antivirus, dan antiprotozoal.  Tujuan penelitian ini untuk  menganalisis hubungan antara tingkat pengetahuan dan kepatuhan pasien rawat jalan terhadap penggunaan antibiotik. Studi ini menggunakan  metode penelitian  deskriptif kuantitatif dengan desain cross-sectional. Penelitian ini melibatkan 100 pasien rawat jalan di RSUD Dr. H. Abdul Moeloek Provinsi Lampung yang pernah mengonsumsi antibiotik. Data dikumpulkan melalui kuesioner yang mengukur tingkat pengetahuan dan kepatuhan pasien dalam penggunaan antibiotik. Hasil penelitian menunjukan pasien dengan pengetahuan baik sebanyak 49% responden, pengetahuan cukup sebanyak 37% responden dan pengetahuan rendah sebanyak 14% responden. Pasien dengan kepatuhan tinggi sebanyak 14% responden, kepatuhan sedang sebanyak 23% responden dan kepatuhan rendah sebanyak 63% responden. Uji analisis hubungan pengetahauan dengan kepatuhan pengobatan dengan chi-square menunjukan terdapat hubungan yang signifikat antara tingkat pengetahuan dan kepatuhan pengobatan pada pasien  rawat jalan dengan nilai p-value = 0,004 (p< 0,05).  
The Correlation Between Mothers’ Knowledge Level And Polio Immunization Coverage At Dahlia Integrated Healthcare Center Of Datarajan saputra, adi; Suswidiantoro, Vicko; Aulika Lestari, Fina; Kartika Putri, Diah
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 3 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i3.4306

Abstract

Polio is a dangerous contagious disease that continues to threaten children, with recent cases re-emerging in Indonesia due to low immunization coverage. A lack of maternal knowledge has been identified as one of the main barriers to the success of polio immunization programs. This study aims to analyze the correlation between mothers’ knowledge level and polio immunization coverage among children at Dahlia Integrated Healthcare Center of Datarajan Village. A quantitative cross-sectional study was conducted from February to April 2025 in Datarajan Village of Tanggamus Regency, involving 47 respondents. Data were collected using a questionnaire on mothers’ knowledge and children’s immunization status and analyzed using univariate and bivariate methods. The results showed that most mothers had a “Moderate” level of knowledge (53%), while the majority (91%) of children had received complete polio immunization. Statistical analysis revealed no significant correlation between mothers’ knowledge level and completeness of polio immunization p value 0,071. The high coverage of complete immunization despite varying knowledge levels highlights the important role of reminders provided by local midwives in ensuring immunization completion. Factors such as a child’s illness were cited as reasons for incomplete immunization. In conclusion, no significant correlation was found between mothers’ knowledge level and polio immunization coverage. The completeness of immunization was more strongly influenced by the proactive role of healthcare workers in reminding parents of immunization schedules.
Optimization of Lip balm Formulation Containing Beetroot Extract (Beta Vulgaris L.) With a Combination of Grapeseed oil and Avocado oil Using the Simplex Lattice Design Method ananda, ardini; Rosanti, Afi Sania; Dwiningrum, Riza; Suswidiantoro, Vicko
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 3 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i3.4318

Abstract

Lip balm, as a semi-solid preparation, can be used to moisturize and protect the lips from dryness and chapping. The use of natural colorants and emollients derived from natural sources is considered safer and more environmentally friendly. Beetroot (Beta vulgaris L.) contains betacyanin as a natural pigment, while grapeseed oil and avocado oil provide emollient properties that help moisturize and nourish the lips. This study aimed to optimize the lip balm formulation containing beetroot extract, grapeseed oil, and avocado oil using Design Expert software version 13 through the Simplex Lattice Design (SLD) method. Ten formulations were produced and evaluated for pH, spreadability, and adhesiveness. The results showed that variations in composition affected the physical characteristics of the lip balm. Grapeseed oil improved spreadability, while avocado oil influenced pH and enhanced adhesiveness. The combination of the three ingredients exhibited synergistic and antagonistic interactions on the physical properties depending on the proportion of each component. The optimum formula was obtained in formulation 5, with a composition of 10% beetroot extract, 10% avocado oil, and 5% grapeseed oil, yielding a desirability value of 1.000. Validation results showed good agreement between predicted and experimental data. Statistical validation using the Wilcoxon test and one-sample t-test indicated p-values > 0.05,suggesting no significant differences. Thus, the model was validated and considered reliable for predicting formulation outcomes. This study successfully optimized a natural lip balm formulation with desirable physical properties, highlighting the potential of beetroot extract as asafe natural colorant in combination with emollient oils.
Antibacterial Effectiveness Test on the Combination of Kersen Leaf (Muntingia calabura L.) and Jackfruit Leaf (Artocarpus heterophyllus L.) Extracts Against The Growth of Staphylococcus aureus Bacteria Mahendri, Adelia Citra; Suswidiantoro, Vicko; Pratiwi, Mida; Pisacha , Iga Mayola
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 3 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i3.4366

Abstract

Kersen leaves (Muntingia calabura L.) and jackfruit leaves (Artocarpus heterophyllus L.) are tropical plants that grow in Indonesia. The phytochemical content of kersen leaves and jackfruit leaves include flavonoids, tannins and saponins. Flavonoids have antibacterial properties because they can fight bacteria in several ways. These substances can interfere with the formation of bacterial genetic material (nucleic acids), damage cell membranes that maintain the contents of bacterial cells, and inhibit the processes used by bacteria to produce energy. This study aims to determine the effectiveness of secondary metabolite compounds against the growth of Staphylococcus aureus bacteria contained in kersen leaves and jackfruit leaves. The research method used is experimental. The sample in this study was a combination of 96% ethanol extract of kersen leaves (Muntingia calabura L.) and jackfruit leaves (Artocarpus heterophyllus. L). The yield of extracts obtained in kersen leaves amounted to 32.1% and avocado leaves 25.42%. Phytochemical screening showed that both samples contained secondary metabolites such as flavonoids, tannins and saponins. The combination of kersen leaf and jackfruit leaf extracts at a concentration ratio of 80:50% and has an average inhibition zone with high effectiveness of 11.10 mm which is classified as strong. This shows that there is a difference, the inhibition zone is better than ampicillin in inhibiting Staphylococcus aureus bacteria.
Co-Authors Abdul Mun&#039;ím Abdul Mun’im Adi Saputra Aini, Sarifatul Alhauri, M.Syarif Amanda, Clarissa Helmavicha ananda, ardini Anggun Fitria Arifah , Linatul Artadevy, Nadhila Fahira Aulika Lestari, Fina Bastian, Arif Alexander Bayu Satriawan, Ahmad Damayanti Abdul Karim, Dewi Daskar, Annajim Deswita, Dwi Diah Kartika Putri Diah Kartika Putri Dimas Thoriq Muhammad Iqbal Dwiningrum , Riza Eka Pratiwi Yunianti Fadia Zahra, Alya Fadlina Chany Saputri Fikriya Ridlawati Gustianing, Defy Humayroh, Suci Iga Mayola Pisacha Islam, Haikal Nur Kaka Widi Rahayu Kartika Putri, Diah Kartika, Jelita Katika Putri, Diah Khoiri, Ahmad Zul Lestari, Fina Aulika Mahendri, Adelia Citra Mayola Pisacha, Iga Mida Pratiwi Mida Pratiwi Miftausakina, Taufiki Muhammad Ridwan Mun'im, Abdul Novita, Riska Reza Nurazizah, Amalia Siti Pisacha , Iga Mayola Pisacha, Iga Mayola Pratama, Dimas Feriza Pratama Pratiwi , Mida Puspita, Cici Chandra Putri, Diah Karika Putri, Diah Kartika putri, Salsa della ananta Riza Dwiningrum Riza Dwiningrum Riza Dwiningrum, Riza Rosanti, Afi Sania Safitri, Indah Saputra, Andika Wahyu Saputra, Cahya Agung Sari, Triyani Anggun Sari Sari, Yuhana Satriawan, Ahmad Bayu Selviyana, Eka Septiana, Elen Sucipto, Ajeng Afriliana Sutomo, Ahmad Syaifurrahman, Amir Tanjung, Salsabila Adelia Tias Eka Rahmawati Wibowo, Catur Ari Wina Safutri Wina Safutri Yanti, Erna Yeni Aryanti Zahra, Annisa