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Journal : International Journal of Educational and Life Sciences (IJELS)

Differences in Creatinine and Ureum Levels 2nd Month and 3rd Month in Tuberculosis Patients of OAT Therapy Azizah Krissan Zahra; Fitriani Kahar; Nurul Qomariyah; Anung Sugihantono; Yusriyanto; Irnawati
International Journal of Educational and Life Sciences Vol. 2 No. 7 (2024): July 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59890/ijels.v2i7.2405

Abstract

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. Tuberculosis patients who test positive must undergo therapy using Anti-Tuberculosis Drugs (OAT). Treatment is divided into two phases, namely the intensive phase is carried out for 2 months with the consumption of rifampicin (R), isoniazid (H), pyrazinamide (Z), and etambutol (E) and the advanced phase is carried out for 4 months with isoniazid (H) and rifampicin (R) OAT. To find out the difference in creatinine and urea levels in the 2nd and 3rd months. Typeof research using quantitative with aprospective cohort research design. The sampling technique uses the purposive sampling method with a sample number of 15. Normality and homogeneity tests were carried out,normal distributed results were obtained and the number of samples did not meet the requirements, so the Wilcoxon statistical test was used. A total of 12 respondents (80.0%) experienced a decrease in urea levels from the 2nd month to the 3rd month. There was a differencein creatinine levels at the 2nd and 3rd months with a p-value of 0.026 (p < 0.05), butthere was no difference inthe urea levelsat the 2nd and 3rd months with a p-value of 0.201 (p < 0.05).    
Co-Authors Ainur Rofiq Sofa Aisyah Imroatus Sholehah Alaa, Siti Amilya Maika Fitriani Ana Nihayah Anisah Rifqotul Istiqomah Anung Sugihantono Azizah Krissan Zahra Azmi Ilmagfiroh Binti Novita Sari Budi Santosa Chamariyah Chamariyah Damanhuri Deny Utomo Devi Merlinda Dewi Sri Susanti Djoko Priyatno Dwi Putri Amelia Eka Lestari Eko Naning Sofyanita Erfan Efendi Erlin Waridatul Chusna Faisol Faisol Fitriani Kahar H. Nurul Huda Handayana, I Gusti Ngurah Yudi Harwin Holilah Desyanti Hendra Hendra Hikmah I Wayan Sudiarta Ica Maulina Rifkiyatul Islami Ifadatul Soimah Immatul Hasanah Inge Andriani Andriani Irnawati Iskandar Iskandar Kunsianah - Kurnia Anisya Maharani Kusyairi Laila Safira Laily Nur Aini Lalu Sahrul Hudha Marzuki Marzuki Masnia Mahardi Yanuar Masrifan Djamil Matrissya Hermita Meyriska Frisna Putri Moh. Aminullah Moh. Asif Syahru Romadhon Moh. Zuinurroziqin Muhammad Irpansyah Munadiyas Silmi Octiyani Muruatul Afifah Nor Hasan Nur Muhjah Khoolidah Nur Salam Nurul Hasanah Nurul Hidayah Rahman Rahman Rakhmawati, Fibri Reza Alfian Rika Selvita Berliana Rika Wulandari Ririh Jatmi Wikandari Rita Rahmawati S.Y. Didik Widiyanto Sakhat Maulidah Siti Antika Ririn Pratiwi Siti Maisaroh Siti Zalfa Pratiwi Subijanto Subijanto Susi Rahayu Teguh Budiharjo Trianah Shofiani Ummu Humairah Via Afkarina Wahyu Rahardjo WARDATUL HASANAH Wardatun Nafiah Widyasari, Rina Wirawan, Rahadi Yayah Ikhda Nevia Yuni Puji Widiastuti Yusriyanto Zakifatul Merry Wahyuni Zakiyyah Zakiyyah Zulfatun Naimah