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Journal : Medula

Physiotherapy for Children with Cerebral Palsy Verizka, Talitha; Berawi, Khairun Nisa; Happy, Terza Aflika; Oktarlina, Rasmi Zakiah; Fiana, Dewi Nur
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1336

Abstract

Cerebral cortex has a motoric area which function in controlling muscle movement. When this area does not develop properly or damaged, cerebral palsy can occur. Cerebral palsy is a disorder of the motoric area of the brain which causes a dysfunction on muscle activities. Eventually, this will lead to limitation of daily activities. Disorder can occur in prenatal, perinatal, or postnatal period. There are four types of cerebral palsy which are spastic, dyskinetic, ataxic, and mixed cerebral palsy. Patient with cerebral palsy experience changes in production of force, balance, and gait as well as a decreased in production of volunteer force. The most dominant sign is balance disorder, but sensoric deficiency could also be seen. In diagnosing cerebral palsy, Levine criteria called POSTER can be used. A child is said to have cerebral palsy when four out of six categories are fulfilled. The aim of treatment of cerebral palsy is to increase functionality, improve capability, and sustain health. Treatment should be done as early as possible and intensive to achieve maximum output. Aside from pharmacological and surgical treatment, mechanic aids, and management of associated medical condition, treatment of cerebral palsy includes physiotherapy. Physiotherapy helps to improve gross motor quality in children with cerebral palsy. Although there are no medicines that can cure cerebral palsy, physiotherapy approach can be done includes re-patterning movement, neurodevelopmental technique (NDT), body weight support treadmill training, atlanto-occipitalisi mobilisation, and standing frame exercise.
Review Literature: Relationship of Food Intake and the Incidence of Dyspepsia Syndrome in Medical Students Napitupulu, Cindy Cecilia Anasthasya; Rahmanisa, Soraya; Happy, Terza Aflika; Sari, Ratna Dewi Puspita
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1443

Abstract

Dyspepsia syndrome is a digestive disorder characterized by symptoms such as epigastric pain, burning, bloating and nausea. In Indonesia, the prevalence is high, with most cases classified as functional dyspepsia. In medical students, poor and irregular diets are common due to academic pressure, busy schedules, and unhealthy lifestyles, which are thought to be the main risk factors for dyspepsia. These habits are further exacerbated by the consumption of unhealthy foods, such as fast food, as well as the habit of eating at irregular times. This study aimed to evaluate the relationship between diet and the incidence of dyspepsia syndrome in medical students in Indonesia through a literature review. A literature search was conducted online using Google Scholar with the keywords “dyspepsia syndrome,” “medical student dyspepsia syndrome,” and “medical student diet.” Of the 635 articles found, 16 were screened based on relevance of content, availability of full text, use of Indonesian language, and time of publication within the last 5 years. Five relevant articles were selected for further review. The review showed a significant association between disordered eating patterns and the incidence of dyspeptic syndrome. Habitual skipping of breakfast, consumption of fast food, eating under stressful conditions, and lack of balanced nutritional intake contributed to the risk of dyspepsia. This conclusion emphasizes the importance of health education on regular diet, stress management, and healthy lifestyle to prevent dyspepsia syndrome and improve the quality of life of medical students.
Peran Flavonoid Sebagai Antiulser dan Antioksidan pada Ulkus Duodenum Zahra, Aulia Jannatuz; Susianti, Susianti; Happy, Terza Aflika; Soleha, Tri Umiana
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1415

Abstract

Duodenal ulcer is a pathological condition characterized by damage to the duodenal mucosa due to an imbalance between protective and aggressive factors, such as gastric acid and pepsin. The primary factors contributing to the development of this ulcer include Helicobacter pylori infection. Additionally, prolonged use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) is also a significant factor in the occurrence of duodenal ulcers, as these drugs inhibit prostaglandin synthesis, which plays a crucial role in mucosal protection. In Indonesia, the prevalence of duodenal ulcers is estimated to be around 11–14%. Flavonoids, as bioactive compounds with antioxidant, anti-inflammatory, and anti-ulcer properties, have been widely studied for their potential in the management of peptic ulcers, including duodenal ulcers. Flavonoids have been shown to inhibit gastric acid secretion, stimulate mucus production, and protect the gastrointestinal mucosa through cytoprotective and antioxidative mechanisms, specifically by inhibiting reactive oxygen species (ROS). Furthermore, flavonoids have the ability to suppress H. pylori growth, thereby contributing to the prevention of ulcer pathogenesis caused by this bacterium. Flavonoids also enhance blood flow to the gastric mucosa and modulate enzymes involved in epithelial defense. Despite these benefits, the main challenges in utilizing flavonoids are their low bioavailability and potential toxicity at high doses. Therefore, further studies are essential to evaluate the efficacy, safety, and formulation optimization of flavonoids to enhance their availability as a natural therapeutic alternative and their application in the clinical treatment of peptic ulcers.
PEMANFAATAN POTENSI ALAMI SEBAGAI ANTIOKSIDAN Happy, Terza Aflika; Septiani, Linda; Graharti, Risti; Andrifianie, Femmy
Medula Vol 15 No 3 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i3.1825

Abstract

Indonesia is one of the world’s most biodiverse countries and possesses a vast potential of medicinal plants as natural therapeutic resources. Many medicinal plants traditionally used by local communities are known to contain secondary metabolites with antioxidant properties. Antioxidants play an essential role in preventing oxidative stress associated with degenerative and infectious diseases. This article aims to review the potential of secondary metabolite compounds from Indonesian medicinal plants as antioxidant agents based on previous studies. This study was conducted using a literature review method by analyzing relevant national and international scientific publications. The results indicate that various medicinal plants, including sweet potato leaves, green tea, roselle, celery, and Peperomia pellucida, contain polyphenolic compounds such as flavonoids, tannins, and phenols, as well as other secondary metabolites including alkaloids, saponins, terpenoids, quinones, coumarins, and anthocyanins. These compounds exhibit antioxidant activity through free radical scavenging, hydrogen atom donation, and inhibition of lipid peroxidation processes. In conclusion, Indonesian medicinal plants demonstrate significant potential as natural sources of antioxidants and offer promising prospects for further development in pharmaceutical and health applications, particularly as raw materials for phytopharmaceutical products and supportive therapies.